I. Lentacker

发表

Crucial factors and emerging concepts in ultrasound-triggered drug delivery.

S. D. De Smedt, B. Geers, Heleen Dewitte, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis

U. Himmelreich, A. Liston, C. Gysemans, 2019, iScience.

mRNA in cancer immunotherapy: beyond a source of antigen

K. Breckpot, Heleen Dewitte, I. Lentacker, 2021, Molecular Cancer.

Broadening the Message: A Nanovaccine Co-loaded with Messenger RNA and α-GalCer Induces Antitumor Immunity through Conventional and Natural Killer T Cells.

S. van Calenbergh, S. D. De Smedt, K. Breckpot, 2019, ACS nano.

Three decades of messenger RNA vaccine development

S. Smedt, S. D. De Smedt, Heleen Dewitte, 2019, Nano Today.

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

C. Heirman, K. Thielemans, C. Goyvaerts, 2016, Molecular therapy. Nucleic acids.

Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound.

E. Stride, O. De Wever, M. Versluis, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles.

R. Vandenbroucke, S. D. De Smedt, J. Demeester, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells.

Kevin Braeckmans, Ranhua Xiong, Ine De Cock, 2014, ACS nano.

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

C. Bachert, B. Schepens, X. Saelens, 2020, Molecular therapy. Nucleic acids.

In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications.

E. Stride, M. Versluis, C. Coussios, 2016, Biomicrofluidics.

Ultrasound responsive doxorubicin-loaded microbubbles; towards an easy applicable drug delivery platform.

S. D. De Smedt, J. Demeester, N. Sanders, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Drug loaded microbubble design for ultrasound triggered delivery

Niek N. Sanders, Stefaan C. De Smedt, Ine Lentacker, 2009 .

Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery

E. Stride, K. Hynynen, M. O’Reilly, 2020, Ultrasound in medicine & biology.

Sonoprinting of nanoparticle-loaded microbubbles: Unraveling the multi-timescale mechanism.

K. Braeckmans, S. D. De Smedt, T. Brans, 2019, Biomaterials.

Design and evaluation of drug loaded microbubbles for ultrasound guided cancer therapy

I. Lentacker, 2009 .

The Role of Ultrasound-Driven Microbubble Dynamics in Drug Delivery: From Microbubble Fundamentals to Clinical Translation.

M. Versluis, S. D. De Smedt, I. Lentacker, 2019, Langmuir : the ACS journal of surfaces and colloids.

Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis.

K. Braeckmans, S. D. De Smedt, N. de Jong, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Non-spherical oscillations drive the ultrasound-mediated release from targeted microbubbles

M. Versluis, F. Mastik, N. de Jong, 2018, Communications Physics.

Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer.

S. D. De Smedt, J. Demeester, N. Sanders, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon.

C. Heirman, K. Thielemans, C. Goyvaerts, 2016, Molecular therapy. Nucleic acids.

Enhancing Nucleic Acid Delivery with Ultrasound and Microbubbles.

S. D. De Smedt, Heleen Dewitte, I. Lentacker, 2019, Methods in molecular biology.

Enhancing nucleic acid delivery with ultrasound and microbubbles.

S. D. De Smedt, N. Sanders, B. Geers, 2013, Methods in molecular biology.

Evaluation of Liposome-Loaded Microbubbles as a Theranostic Tool in a Murine Collagen-Induced Arthritis Model

C. Vanhove, M. Versluis, S. D. De Smedt, 2022, Scientia Pharmaceutica.

Ultrasound exposure of lipoplex loaded microbubbles facilitates direct cytoplasmic entry of the lipoplexes.

R. Vandenbroucke, S. D. De Smedt, J. Demeester, 2009, Molecular pharmaceutics.

Microbubbles which bind and protect DNA against nucleases.

S. D. De Smedt, J. Demeester, N. Sanders, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Sonoprinting in 3D: liposome-loaded microbubbles and ultrasound promote drug delivery in tumor spheroids

M. Versluis, N. Rivron, S. Gac, 2020 .

Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles.

S. Meairs, S. D. De Smedt, J. Demeester, 2011, Molecular pharmaceutics.

Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery.

O. De Wever, S. D. De Smedt, J. Demeester, 2013, Small.

Fluorine MR Imaging Probes Dynamic Migratory Profiles of Perfluorocarbon-Loaded Dendritic Cells After Streptozotocin-Induced Inflammation

U. Himmelreich, C. Gysemans, S. D. De Smedt, 2022, Molecular Imaging and Biology.

Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB Opening.

M. Hennerici, S. Meairs, M. Fatar, 2014, Annals of neurosciences.

Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening

M. Hennerici, S. Meairs, M. Fatar, 2013, Molecular therapy. Nucleic acids.

Immunopeptidomics-based design of highly effective mRNA vaccine formulations against Listeria monocytogenes

L. Martens, F. Impens, I. Lentacker, 2022, bioRxiv.

Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model

U. Himmelreich, C. Gysemans, B. Manshian, 2019, Magnetic Resonance Materials in Physics, Biology and Medicine.

Theranostic mRNA-loaded Microbubbles in the Lymphatics of Dogs: Implications for Drug Delivery

L. Duchateau, K. Vanderperren, J. Saunders, 2015, Theranostics.

The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy.

S. D. De Smedt, C. Heirman, K. Thielemans, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Lipoplex‐Loaded Microbubbles for Gene Delivery: A Trojan Horse Controlled by Ultrasound

S. Smedt, J. Demeester, N. Sanders, 2007 .

Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes

L. Martens, F. Impens, I. Lentacker, 2022, Nature Communications.

Electronic Supplementary Material Tri-modal In Vivo Imaging of Pancreatic Islets Transplanted Subcutaneously in Mice Journal: Molecular Imaging and Biology

U. Himmelreich, B. Manshian, S. Soenen, 2018 .

Understanding ultrasound induced sonoporation: definitions and underlying mechanisms.

C T W Moonen, C. Moonen, R. Deckers, 2014, Advanced drug delivery reviews.

Physical transfection technologies for macrophages and dendritic cells in immunotherapy

K. Braeckmans, S. D. De Smedt, I. Lentacker, 2020, Expert opinion on drug delivery.

Sonoprinting promotes drug delivery with liposome-loaded microbubbles and ultrasound

M. Versluis, I. Lentacker, G. Lajoinie, 2019, The Journal of the Acoustical Society of America.

Opening doors with ultrasound and microbubbles: beating biological barriers to promote drug delivery.

S. D. De Smedt, I. Lentacker, G. Lajoinie, 2021, Advanced drug delivery reviews.

Biocompatible Lipid‐Coated Persistent Luminescent Nanoparticles for In Vivo Imaging of Dendritic Cell Migration

C. Vanhove, K. Braeckmans, D. Poelman, 2019, Particle & Particle Systems Characterization.

Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells.

C. Vanhove, O. De Wever, K. Braeckmans, 2021, Biomaterials science.

Photoporation with Biodegradable Polydopamine Nanosensitizers Enables Safe and Efficient Delivery of mRNA in Human T Cells

K. Braeckmans, S. D. De Smedt, T. Brans, 2021, Advanced Functional Materials.

Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells.

K. Braeckmans, R. De Rycke, M. Lamkanfi, 2021, Nanoscale.

The dawn of mRNA vaccines: The COVID-19 case

S. D. De Smedt, Heleen Dewitte, I. Lentacker, 2021, Journal of Controlled Release.

Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer.

K. Remaut, I. Lentacker, W. Ceelen, 2022, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Co‐delivery of nucleoside‐modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA

C. Vanhove, M. V. Van Bockstal, S. D. De Smedt, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro.

R. Vandenbroucke, C. Libert, S. D. De Smedt, 2014, Journal of controlled release : official journal of the Controlled Release Society.

mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells.

R. Vandenbroucke, C. Libert, S. D. De Smedt, 2011, Biomaterials.

Tri-modal In vivo Imaging of Pancreatic Islets Transplanted Subcutaneously in Mice

U. Himmelreich, B. Manshian, S. Soenen, 2018, Molecular Imaging and Biology.

Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and ¹⁹F-MRI tracking of dendritic cells.

Sayuan Liang, Uwe Himmelreich, Stefaan C De Smedt, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA.

Stefaan C De Smedt, Ine Lentacker, R. Vandenbroucke, 2006, Langmuir : the ACS journal of surfaces and colloids.

Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment

S. Smedt, K. Breckpot, Heleen Dewitte, 2014 .

The ReNAissanCe of mRNA-based cancer therapy

C. Heirman, K. Thielemans, K. Breckpot, 2015, Expert review of vaccines.

Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across

S. D. De Smedt, K. Remaut, N. Sanders, 2021, Advanced Drug Delivery Reviews.

Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved.

Stefaan C De Smedt, Ine Lentacker, S. D. De Smedt, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Microvascular Injury and Perfusion Changes Induced by Ultrasound and Microbubbles in a Machine-Perfused Pig Liver.

I. Lentacker, M. Averkiou, M. Izamis, 2016, Ultrasound in medicine & biology.

Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

T. De Beer, P. Cullis, S. D. De Smedt, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Self-assembled liposome-loaded microbubbles: The missing link for safe and efficient ultrasound triggered drug-delivery.

Stephen Meairs, Stefaan C De Smedt, Ine Lentacker, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Tumor cell killing efficiency of doxorubicin loaded microbubbles after ultrasound exposure.

S. D. De Smedt, J. Demeester, N. Sanders, 2010, Journal of controlled release : official journal of the Controlled Release Society.

mRNA in cancer immunotherapy: beyond a source of antigen

K. Breckpot, Heleen Dewitte, I. Lentacker, 2021, Molecular cancer.

Can Ultrasound Solve the Transport Barrier of the Neural Retina?

R. Vandenbroucke, S. Smedt, J. Demeester, 2008, Pharmaceutical Research.

New strategies for nucleic acid delivery to conquer cellular and nuclear membranes.

R. Vandenbroucke, S. D. De Smedt, J. Demeester, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles.

M. Versluis, S. D. De Smedt, I. Lentacker, 2016, Biomaterials.

Acoustical properties of individual liposome-loaded microbubbles.

Nico de Jong, Telli Faez, Michel Versluis, 2012, Ultrasound in medicine & biology.

Dynamic Fluorescence Microscopy of Cellular Uptake of Intercalating Model Drugs by Ultrasound-Activated Microbubbles

C. Moonen, R. Deckers, C. Bos, 2017, Molecular Imaging and Biology.

Doxorubicin liposome-loaded microbubbles for contrast imaging and ultrasound-triggered drug delivery

A. Novell, J. Escoffre, A. Bouakaz, 2013, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

Non-spherical oscillations drive the ultrasound-mediated release from targeted microbubbles

M. Versluis, F. Mastik, N. de Jong, 2018, Communications Physics.

Ultrasound assisted drug delivery. Preface.

C. Moonen, I. Lentacker, 2014, Advanced drug delivery reviews.

Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium

D. Peer, G. Van Isterdael, S. D. De Smedt, 2023, Nature Nanotechnology.

mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells.

R. Vandenbroucke, C. Libert, S. D. De Smedt, 2011, Biomaterials.

Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening

M. Hennerici, S. Meairs, M. Fatar, 2013, Molecular therapy. Nucleic acids.

Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis.

K. Braeckmans, S. D. De Smedt, N. de Jong, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

N. Devoogdt, Y. De Vlaeminck, C. Goyvaerts, 2023, Theranostics.

Dependence of sonoporation efficiency on microbubble size: An in vitro monodisperse microbubble study.

S. D. De Smedt, I. Lentacker, T. Segers, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Considerations on the design of lipid-based mRNA vaccines against cancer.

I. Lentacker, Rein Verbeke, Sofie Meulewaeter, 2023, Journal of molecular biology.

Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.

R. De Rycke, K. Bracke, K. Raemdonck, 2024, Nano letters.

Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics.

G. Berx, K. Braeckmans, S. D. De Smedt, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Optimizing high-intensity focused ultrasound-induced immunogenic cell-death using passive cavitation mapping as a monitoring tool.

I. Lentacker, G. Lajoinie, Y. Engelen, 2024, Journal of controlled release : official journal of the Controlled Release Society.