M. Manolson

发表

STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)-ATPase subunit Vph1p.

B. Taillon, B. Roberts, B. Wu, 1994, The Journal of biological chemistry.

Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae

K. Becherer, R. Wright, M. Manolson, 1991, Molecular and cellular biology.

Evolution of the vacuolar H+-ATPase: implications for the origin of eukaryotes.

Masasuke Yoshida, J. Gogarten, T. Date, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells

Eunice E. Cho, G. Giaever, M. Minden, 2015, Apoptosis.

Increased expression of activating factors in large osteoclasts could explain their excessive activity in osteolytic diseases

J. Heersche, M. Manolson, A. Gramoun, 2007, Journal of cellular biochemistry.

Function of the COOH-terminal Domain of Vph1p in Activity and Assembly of the Yeast V-ATPase*

M. Manolson, M. Forgac, X. Leng, 1998, The Journal of Biological Chemistry.

The plant vacuolar Na+/H+ antiport.

E. Blumwald, M. P. Apse, M. Manolson, 1994, Symposia of the Society for Experimental Biology.

Fibronectin inhibits osteoclastogenesis while enhancing osteoclast activity via nitric oxide and interleukin‐1β‐mediated signaling pathways

J. Heersche, M. Manolson, J. Sodek, 2010, Journal of cellular biochemistry.

IL‐1α and IL‐1β have different effects on formation and activity of large osteoclasts

J. Heersche, M. Manolson, Diana P Trebec-Reynolds, 2010, Journal of cellular biochemistry.

Bone matrix proteins and extracellular acidification: Potential co‐regulators of osteoclast morphology

S. Grinstein, O. Rotstein, T. Nordström, 2010, Journal of cellular biochemistry.

Regulation of Cytoplasmic pH in Osteoclasts

S. Grinstein, G. Brisseau, O. Rotstein, 1995, The Journal of Biological Chemistry.

A Novel Model System for Characterization of Phagosomal Maturation, Acidification, and Intracellular Collagen Degradation in Fibroblasts*

G. Downey, C. McCulloch, M. Manolson, 2000, The Journal of Biological Chemistry.

Purification of active human vacuolar H+-ATPase in native lipid-containing nanodiscs

Yeqi Yao, M. Manolson, S. Wilkens, 2021, The Journal of biological chemistry.

Interleukin-1 Increases Vacuolar-type H-ATPase Activity in Murine Peritoneal Macrophages (*)

S. Grinstein, G. Brisseau, O. Rotstein, 1996, The Journal of Biological Chemistry.

Methylglyoxal Inhibits the Binding Step of Collagen Phagocytosis*

C. Simmons, C. McCulloch, M. Manolson, 2007, Journal of Biological Chemistry.

Protein kinase C activation accelerates proton extrusion by vacuolar‐type H+‐ATPases in murine peritoneal macrophages

S. Grinstein, G. Brisseau, O. Rotstein, 1994, FEBS letters.

N‐linked glycosylation of a subunit isoforms is critical for vertebrate vacuolar H+‐ATPase (V‐ATPase) biosynthesis

R. Reithmeier, Yeqi Yao, M. Manolson, 2018, Journal of cellular biochemistry.

N‐Linked Glycosylation Is Required for Vacuolar H+‐ATPase (V‐ATPase) a4 Subunit Stability, Assembly, and Cell Surface Expression

R. Reithmeier, Yeqi Yao, M. Manolson, 2016, Journal of cellular biochemistry.

Isolation and Characterization of PEP3,

K. Becherer, T. Wright, M. Manolson, 2022 .

VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy

J. Rilstone, C. Ackerley, I. Nishino, 2013, Acta Neuropathologica.

The R740S mutation in the V‐ATPase a3 subunit results in osteoclast apoptosis and defective early‐stage autophagy

J. Aubin, M. Manolson, Noelle Ochotny, 2013, Journal of cellular biochemistry.

The R740S mutation in the V‐ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis

J. Aubin, M. Manolson, Valentin Jaumouillé, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Alternative Mechanisms of Vacuolar Acidification in H+-ATPase-deficient Yeast*

S. Grinstein, N. Demaurex, M. Manolson, 1999, The Journal of Biological Chemistry.

Mouse FLRT2 Interacts with the Extracellular and Intracellular Regions of FGFR2

M. Manolson, S. Gong, K. Wei, 2011, Journal of dental research.

Evidence That the NH2 Terminus of Vph1p, an Integral Subunit of the V0 Sector of the Yeast V-ATPase, Interacts Directly with the Vma1p and Vma13p Subunits of the V1Sector*

M. Manolson, C. Landolt-Marticorena, Judy Correa, 2000, The Journal of Biological Chemistry.

Dynamic measurement of the pH of the Golgi complex in living cells using retrograde transport of the verotoxin receptor

S. Grinstein, C. Lingwood, M. Manolson, 1996, The Journal of cell biology.

Effects of Vitaxin®, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro

S. Dixon, S. Sims, J. Heersche, 2007, Journal of cellular biochemistry.

Chronic Extracellular Acidosis Induces Plasmalemmal Vacuolar Type H+ ATPase Activity in Osteoclasts*

S. Grinstein, G. Brisseau, O. Rotstein, 1997, The Journal of Biological Chemistry.

Isolation and characterization of PEP5, a gene essential for vacuolar biogenesis in Saccharomyces cerevisiae.

R. Wright, C. Woolford, M. Manolson, 1990, Genetics.

The V–ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice

A. Flenniken, J. Rossant, J. Aubin, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Nitric oxide in human gingival crevicular fluid after orthodontic force application.

M. Manolson, S. Suri, S. Gong, 2014, Archives of oral biology.

Expression of nitric oxide synthases in orthodontic tooth movement.

M. Manolson, D. Nilforoushan, 2009, The Angle orthodontist.

Molecular markers of early orthodontic tooth movement.

C. Simmons, M. Manolson, P. J. Brooks, 2009, The Angle orthodontist.

The V-ATPase a3 Subunit: Structure, Function and Therapeutic Potential of an Essential Biomolecule in Osteoclastic Bone Resorption

R. Zirngibl, M. Manolson, A. Chu, 2021, International journal of molecular sciences.

Photoaffinity labeling and characterization of the cloned purine-cytosine transport system in Saccharomyces cerevisiae.

M. Chevallier, M. Manolson, R. Schmidt, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Evolution of vacuolar H+-ATPases: immunological relationships of the nucleotide-binding subunits

D. Apps, M. Manolson, R. J. Poole, 1989 .

Regulation of vacuolar H(+)-ATPase in microglia by RANKL.

M. Manolson, L. Holliday, Noelle Ochotny, 2009, Biochemical and biophysical research communications.

The relative contribution of cysteine proteinases and matrix metalloproteinases to the resorption process in osteoclasts derived from long bone and scapula.

M. Manolson, J. Heersche, S. Shorey, 2004, Bone.

Evidence for a conserved 95-120 kDa subunit associated with and essential for activity of V-ATPases.

M. Manolson, D. Proteau, E. W. Jones, 1992, The Journal of experimental biology.

8‐azidoadenine: a photoaffinity label for the purine transport system in saccharomyces cerevisiae

K. Angelides, M. Manolson, R. J. Poole, 1981, FEBS letters.

Novel c.G630A TCIRG1 mutation causes aberrant splicing resulting in an unusually mild form of autosomal recessive osteopetrosis

R. Zirngibl, Yeqi Yao, R. Mendoza-Londono, 2019, Journal of cellular biochemistry.

Molecular mechanisms of cutis laxa– and distal renal tubular acidosis–causing mutations in V-ATPase a subunits, ATP6V0A2 and ATP6V0A4

R. Reithmeier, Yeqi Yao, M. Manolson, 2018, The Journal of Biological Chemistry.

The a3 Isoform of the 100-kDa V-ATPase Subunit Is Highly but Differentially Expressed in Large (≥10 Nuclei) and Small (≤5 Nuclei) Osteoclasts*

Yeqi Yao, J. Heersche, Hesheng Yu, 2003, Journal of Biological Chemistry.

Proton transport and phosphorylation of tonoplast polypeptides from zucchini are stimulated by the phospholipid platelet-activating factor.

G. Martiny-Baron, D. Hecker, M. Manolson, 1992, Plant physiology.

Site-directed Mutagenesis of the 100-kDa Subunit (Vph1p) of the Yeast Vacuolar (H+)-ATPase*

M. Manolson, Qing Liu, M. Forgac, 1996, The Journal of Biological Chemistry.

Advances in understanding N-glycosylation structure, function, and regulation in health and disease.

M. Manolson, S. Esmail, 2021, European journal of cell biology.

Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro Osteoclast Differentiation in Arthritis study.

S. M. Sims, Lukasz Kurgan, S. Dixon, 2013, Arthritis and rheumatism.

Controlled bone formation using ultrasound-triggered release of BMP-2 from liposomes.

Ross Williams, P. Burns, M. Manolson, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Identification of 3-O-(4-benzoyl)benzoyladenosine 5'-triphosphate- and N,N'-dicyclohexylcarbodiimide-binding subunits of a higher plant H+-translocating tonoplast ATPase.

P. A. Rea, M. Manolson, R. J. Poole, 1985, The Journal of biological chemistry.

Satisfaction and Awareness of Systemic Psoriasis Treatments: A National Survey Comparing Biologic and Nonbiologic Users

M. Manolson, B. Barankin, V. Sandhu, 2019, Journal of cutaneous medicine and surgery.

Nitric oxide enhances osteoclastogenesis possibly by mediating cell fusion.

M. Glogauer, M. Manolson, A. Gramoun, 2009, Nitric oxide : biology and chemistry.

The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase.

D. Botstein, J. Mulholland, B. Roberts, 1992, The Journal of biological chemistry.

Benzo[a]pyrene inhibits osteoclastogenesis by affecting RANKL-induced activation of NF-kappaB.

Howard C. Tenenbaum, M. Manolson, I. Voronov, 2008, Biochemical pharmacology.

The Vacuolar Proton ATPase (V-ATPase): Regulation and Therapeutic Targeting

M. Manolson, N. Kartner, 2016 .

V-ATPase subunit interactions: the long road to therapeutic targeting.

M. Manolson, N. Kartner, 2012, Current protein & peptide science.

Saccharomyces cerevisiae . required for vacuolar biogenesis in Isolation and characterization of PEP 3 , a gene

K. Becherer, M. Manolson, E. W. Jones, 1991 .

Topology, glycosylation and conformational changes in the membrane domain of the vacuolar H+‐ATPase a subunit

Yeqi Yao, M. Manolson, N. Kartner, 2013, Journal of cellular biochemistry.

Osteoclasts and their circulating precursors in rheumatoid arthritis: Relationships with disease activity and bone erosions

S. Dixon, R. Harrison, S. Komarova, 2020, Bone reports.

cDNA sequence and homologies of the "57-kDa" nucleotide-binding subunit of the vacuolar ATPase from Arabidopsis.

B. F. Ouellette, M. Manolson, R. J. Poole, 1988, The Journal of biological chemistry.

Irreversible inhibition of H+-ATPase of higher plant tonoplast by chaotropic anions: evidence for peripheral location of nucleotide-binding subunits

P. A. Rea, D. Sanders, M. Manolson, 1987 .

VEGF‐A expression in osteoclasts is regulated by NF‐κB induction of HIF‐1α

J. Heersche, M. Manolson, Diana P Trebec-Reynolds, 2010, Journal of cellular biochemistry.

Inhibition of Osteoclast Bone Resorption by Disrupting Vacuolar H+-ATPase a3-B2 Subunit Interaction*

A. Datti, Yeqi Yao, M. Manolson, 2010, The Journal of Biological Chemistry.

Substrate- and Inhibitor-induced Conformational Changes in the Yeast V-ATPase Provide Evidence for Communication between the Catalytic and Proton-translocating Sectors*

M. Manolson, Judy Correa, Carolina Landolt-Marticorena, 1999, The Journal of Biological Chemistry.

Effects of Human a3 and a4 Mutations That Result in Osteopetrosis and Distal Renal Tubular Acidosis on Yeast V-ATPase Expression and Activity*

H. V. von Schroeder, Yeqi Yao, J. Heersche, 2006, Journal of Biological Chemistry.

Luteolin inhibition of V‐ATPase a3–d2 interaction decreases osteoclast resorptive activity

A. Datti, Yeqi Yao, M. Manolson, 2013, Journal of cellular biochemistry.

Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association

C. Deber, R. Botelho, Yeqi Yao, 2023, International journal of molecular sciences.

Novel techniques in the development of osteoporosis drug therapy: the osteoclast ruffled-border vacuolar H+-ATPase as an emerging target

M. Manolson, N. Kartner, 2014, Expert opinion on drug discovery.

V-ATPase a3-d2 and a3-B2 Subunit Interaction in Osteoclasts are Viable Targets for Anti-resorptive Therapeutics

M. Manolson, G. Crasto, 2012 .

Inhibition of osteoclast differentiation by polycyclic aryl hydrocarbons is dependent on cell density and RANKL concentration.

Howard C. Tenenbaum, J. Heersche, M. Manolson, 2005, Biochemical pharmacology.

Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells

Eunice E. Cho, G. Giaever, M. Minden, 2015, Apoptosis.

The increased in vitro osteoclastogenesis in patients with rheumatoid arthritis is due to increased percentage of precursors and decreased apoptosis - the In Vitro Osteoclast Differentiation in Arthritis (IODA) study.

Lukasz Kurgan, S. Dixon, R. Harrison, 2011, Bone.

Characterization and subcellular localization of target membrane soluble NSF attachment protein receptors (t-SNAREs) in macrophages. Syntaxins 2, 3, and 4 are present on phagosomal membranes.

S. Grinstein, A. Klip, O. Rotstein, 1996, Journal of immunology.

The VPH2 gene encodes a 25 kDa protein required for activity of the yeast vacuolar H+‐ATPase

M. Manolson, A. Bachhawat, J. D. Garman, 1993, Yeast.

Osteopetrosis Mutation R444L Causes Endoplasmic Reticulum Retention and Misprocessing of Vacuolar H+-ATPase a3 Subunit*

M. Glogauer, M. Manolson, N. Kartner, 2012, The Journal of Biological Chemistry.

Subunit a 3-ATPase + Misprocessing of Vacuolar H Endoplasmic Reticulum Retention and Osteopetrosis Mutation R 444 L Causes Molecular Bases of Disease :

M. Glogauer, M. Manolson, N. Kartner, 2012 .

Control of Excitatory Synaptic Transmission by C-terminal Src Kinase*

C. L. Kwan, Gang Lei, J. Macdonald, 2008, Journal of Biological Chemistry.

RETRACTED: VMA21 Deficiency Causes an Autophagic Myopathy by Compromising V-ATPase Activity and Lysosomal Acidification

J. Rilstone, C. Ackerley, I. Nishino, 2009, Cell.

VMA21 Deficiency Causes an Autophagic Myopathy by Compromising V-ATPase Activity and Lysosomal Acidification (Retracted article. See vol. 142, pg. 984, 2010)

J. Rilstone, C. Ackerley, I. Nishino, 2009 .

The αvβ3 integrin as a therapeutic target for inhibition of bone resorption

J. Suzich, M. Manolson, J. Bashutski, 2004, Arthritis Research & Therapy.

Effects of Human a 3 and a 4 Mutations that Result in Osteopetrosis and Distal Renal Tubular Acidosis on Yeast V-ATPase Expression and Activity *

Yeqi Yao, J. Heersche, M. Manolson, 2006 .

An Evaluation of Psoriasis Patient Perceptions and Understanding of Biosimilars: A Canadian Survey Comparing Biologic and Nonbiologic Users

M. Manolson, A. Ighani, Jane Y Wang, 2018, Journal of cutaneous medicine and surgery.

VEGF‐A expression in osteoclasts is regulated by NF‐κB induction of HIF‐1α

J. Heersche, M. Manolson, Diana P Trebec-Reynolds, 2010, Journal of cellular biochemistry.

Osteopetrosis Mutation R444L Causes Endoplasmic Reticulum Retention and Misprocessing of Vacuolar H+-ATPase a3 Subunit*

M. Glogauer, M. Manolson, N. Kartner, 2012, The Journal of Biological Chemistry.

The Osteoporosis Primer: Osteoclasts: characteristics and regulation of formation and activity

J. Heersche, M. Manolson, 2000 .

Retraction Notice to: VMA21 Deficiency Causes an Autophagic Myopathy by Compromising V-ATPase Activity and Lysosomal Acidification

J. Rilstone, C. Ackerley, I. Nishino, 2010, Cell.

Controlled bone formation using ultrasound-triggered release of BMP-2 from liposomes.

Ross Williams, P. Burns, M. Manolson, 2016, Journal of controlled release : official journal of the Controlled Release Society.