D. Mock

D. Mock, S. Schenker, G. Henderson, 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Human placental biotin transport: normal characteristics and effect of ethanol.

D. Mock, S. Schenker, T. Frosto, 1993, Alcoholism, clinical and experimental research.

Red Cell Volume Can Be Accurately Determined in Sheep Using a Nonradioactive Biotin Label

J. Widness, L. Burmeister, R. Strauss, 2008, Pediatric Research.

Antibodies provoked by the transfusion of biotin‐labeled red cells

R. Strauss, D. Mock, G. Lankford, 1999, Transfusion.

The clearance and metabolism of biotin administered intravenously to pigs in tracer and physiologic amounts is much more rapid than previously appreciated.

G. Kearns, D. Mock, K. S. Wang, 2001, The Journal of nutrition.

Tracking donor RBC survival in premature infants: agreement of multiple populations of biotin-labeled RBCs with Kidd antigen mismatched RBCs

J. Widness, R. Strauss, D. Mock, 2013, Pediatric Research.

Lymphocyte propionyl-CoA carboxylase and its activation by biotin are sensitive indicators of marginal biotin deficiency in humans.

D. Mock, N. Mock, A. Bogusiewicz, 2006, The American journal of clinical nutrition.

Models for the red blood cell lifespan

C. Hollot, Y. Chait, J. Horowitz, 2016, Journal of Pharmacokinetics and Pharmacodynamics.

lambsresponses during anemia and its correction in

E. Bell, J. Widness, L. Burmeister, 2013 .

Adaptive responses during anemia and its correction in lambs.

E. Bell, J. Widness, L. Burmeister, 2000, Journal of applied physiology.

Quantitative measurement of plasma 3-hydroxyisovaleryl carnitine by LC-MS/MS as a novel biomarker of biotin status in humans.

D. Mock, Lindsay M Pack, J. Moran, 2010, Analytical chemistry.

Current knowledge on biotin nutrition in fish and research perspectives

D. Mock, P. Sarker, G. Vandenberg, 2015 .

Biotin: Physiology, Dietary Sources, and Requirements

D. Mock, 2013 .

Introduction to "Advances in understanding of the biological role of biotin at the clinical, biochemical, and molecular level".

D. Mock, H. Said, 2009, The Journal of nutrition.

Marginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in mice.

D. Mock, 2009, The Journal of nutrition.

Biotin status assessed longitudinally in pregnant women.

D. Stadler, D. Mock, N. Mock, 1997, The Journal of nutrition.

Regulation of intestinal biotin transport in the rat: effect of biotin deficiency and supplementation.

D. Mock, H. Said, J. C. Collins, 1989, The American journal of physiology.

Marginal biotin deficiency is teratogenic in mice and perhaps humans: a review of biotin deficiency during human pregnancy and effects of biotin deficiency on gene expression and enzyme activities in mouse dam and fetus.

D. Mock, 2005, The Journal of nutritional biochemistry.

3-Hydroxypropionic acid and methylcitric acid are not reliable indicators of marginal biotin deficiency in humans.

D. Mock, P. Stumbo, Nadine S. Carnell, 2004, The Journal of nutrition.

Biochemical and Molecular Actions of Nutrients Marginal Biotin Deficiency Is Teratogenic in ICR Mice

D. Mock, D. Hansen, N. Mock, 2003 .

Red blood cell volume can be independently determined in vitro using sheep and human red blood cells labeled at different densities of biotin

J. Widness, L. Burmeister, R. Strauss, 2009, Transfusion.

RBCs labeled at two biotin densities permit simultaneous and repeated measurements of circulating RBC volume

J. Widness, L. Burmeister, R. Strauss, 2004, Transfusion.

Measurement of circulating red cell volume using biotin‐labeled red cells: validation against 51Cr‐labeled red cells

J. Widness, L. Burmeister, R. Strauss, 1999, Transfusion.

Randomized Trial of Liberal Versus Restrictive Guidelines for Red Blood Cell Transfusion in Preterm Infants

E. Bell, J. Widness, K. Johnson, 2005, Pediatrics.

Red blood cell (RBC) survival determined in humans using RBCs labeled at multiple biotin densities

J. Widness, R. Strauss, D. Mock, 2011, Transfusion.

Comparison of red blood cell survival in sheep determined using red blood cells labeled with either biotin at multiple densities or [14C]cyanate: validation of a model to study human physiology and disease

J. Widness, R. Strauss, D. Mock, 2012, Transfusion.

Low temperature EPR spectroscopic characterization of the interaction of cytochrome P-450cam with a spin label analog of metyrapone.

B. Griffin, D. Mock, J. Peterson, 1982, The Journal of biological chemistry.

Biotin Deficiency Complicating Parenteral Alimentation: Diagnosis, Metabolic Repercussions, and Treatment a

D. Mock, R. Holman, L. Sweetman, 1985, The Journal of pediatrics.

Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylases.

D. Mock, W. Sealey, D. Hansen, 2005, The Journal of nutrition.

Biotin dependency due to a defect in biotin transport

M. Jennings, S. Cederbaum, J. Zempleni, 2002 .

Marginal biotin deficiency during normal pregnancy.

D. Mock, J. Quirk, N. Mock, 2002, The American journal of clinical nutrition.

Biotin dependency due to a defect in biotin transport.

M. Jennings, S. Cederbaum, J. Zempleni, 2002, The Journal of clinical investigation.

Marginal biotin deficiency is teratogenic.

J. Zempleni, D. Mock, Janos Zempleni, 2000, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Biotin status: which are valid indicators and how do we know?

D. Mock, 1999, The Journal of nutrition.

Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants

M. Dyken, D. Mock, 1997, Neurology.

Conflicting indicators of biotin status from a cross-sectional study of normal pregnancy.

D. Stadler, D. Mock, D. M. Mock, 1997, Journal of the American College of Nutrition.

Biotin deficiency in rats: disturbances of leucine metabolism are detectable early.

D. Mock, N. Mock, 1992, The Journal of nutrition.

Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency.

D. Mock, P. Stumbo, M. I. Malik, 1997, The American journal of clinical nutrition.

Identification of biotin sulfone, bisnorbiotin methyl ketone, and tetranorbiotin-l-sulfoxide in human urine.

J. Zempleni, D. Mock, D. B. Mccormick, 1997, The American journal of clinical nutrition.

Biotin deficiency complicating parenteral alimentation.

D. Mock, 1983, JAMA.

Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis

F. Sedel, D. Mock, A. Tourbah, 2016, Neuropharmacology.

Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis

D. Mock, G. Defer, Delphine Bernard, 2016, Expert opinion on drug metabolism & toxicology.

Skin manifestations of biotin deficiency.

D. Mock, 1991, Seminars in dermatology.

Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.

D. Mock, H. Spencer, J. Moran, 2010, The American journal of clinical nutrition.

Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood.

T. I. Vlasova, D. Mock, N. Mock, 2005, The Journal of nutrition.

Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans.

J. Zempleni, D. Mock, 1999, The Journal of nutrition.

Disturbances in biotin metabolism in children undergoing long-term anticonvulsant therapy.

R. Nelson, D. Mock, N. Mock, 1998, Journal of pediatric gastroenterology and nutrition.

blood mononuclear cells Uptake and metabolism of biotin by human peripheral

J. Zempleni, D. Mock, 2016 .

Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans.

D. Mock, G. Boysen, Thomas D. Horvath, 2012, The Journal of nutrition.

Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans.

D. Mock, G. Boysen, H. Spencer, 2011, The Journal of nutrition.

Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.

D. Mock, H. Spencer, J. Moran, 2011, The Journal of nutrition.

Marginal biotin deficiency during normal pregnancy 1,2,3

D. Mock, J. Quirk, N. Mock, 2008 .

Lymphocyte propionyl-CoA carboxylase and accumulation of odd-chain fatty acid in plasma and erythrocytes are useful indicators of marginal biotin deficiency small star, filled.

D. Mock, Nadine S. Carnell, L. Swift, 2002, The Journal of nutritional biochemistry.

Lymphocyte propionyl-CoA carboxylase is an early and sensitive indicator of biotin deficiency in rats, but urinary excretion of 3-hydroxypropionic acid is not.

D. Mock, N. Mock, 2002, The Journal of nutrition.

Certain immune markers are not good indicators of mild to moderate biotin deficiency in rats.

R. Helm, D. Mock, N. Mock, 2001, The Journal of nutrition.

A direct streptavidin-binding assay does not accurately quantitate biotin in human urine.

D. Mock, J. Nyalala, R. M. Raguseo, 2001, The Journal of nutrition.

Marginal Biotin Deficiency is Teratogenic (44458)

J. Zempleni, D. Mock, 2000 .

Symposium: Nutrition, Biochemistry and Molecular Biology of Biotin

D. Mock, 1999 .

Uptake and metabolism of biotin by human peripheral blood mononuclear cells.

J. Zempleni, D. Mock, 1998, The American journal of physiology.

Uptake and metabolism of biotin by human peripheral blood mononuclear cells.

J. Zempleni, D. Mock, 1998, American journal of physiology. Cell physiology.

Profound biotinidase deficiency in two asymptomatic adults.

M. Blitzer, D. Mock, B. Wolf, 1997, American journal of medical genetics.

Urinary biotin analogs increase in humans during chronic supplementation: the analogs are biotin metabolites.

D. Mock, G. M. Heird, 1997, The American journal of physiology.

Biotin and biotin analogs in human urine: biotin accounts for only half of the total.

D. Mock, J. Cazin, G. Lankford, 1993, The Journal of nutrition.

A sequential, solid-phase assay for biotin in physiologic fluids that correlates with expected biotin status.

D. Mock, D. Dubois, D. M. Mock, 1986, Analytical biochemistry.

Biotin deficiency complicating parenteral alimentation: diagnosis, metabolic repercussions, and treatment.

D. Mock, R. Holman, L. Sweetman, 1985, Annals of the New York Academy of Sciences.

Biotin homeostasis during the cell cycle

J. Zempleni, D. Mock, J Zempleni, 2001, Nutrition Research Reviews.

Utilization of biotin in proliferating human lymphocytes.

J. Zempleni, D. Mock, D. M. Mock, 2000, The Journal of nutrition.

Symposium : Mechanistic Aspects of Vitamin and Coenzyme Utilization and Function : A Symposium in Recognition of the Distinguished Career of Donald B . McCormick Utilization of Biotin in Proliferating Human Lymphocytes 1 , 2

J. Zempleni, D. Mock, 2000 .

Chemical synthesis of biotinylated histones and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis/streptavidin-peroxidase.

J. Zempleni, D. Mock, 1999, Archives of biochemistry and biophysics.

Antibodies against biotin‐labeled red blood cells can shorten posttransfusion survival

S. Stowell, J. Widness, R. Strauss, 2022, Transfusion.

Adequate intake of biotin in pregnancy: why bother?

D. Mock, 2014, The Journal of nutrition.

Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MS

D. Mock, G. Boysen, Thomas D. Horvath, 2011, Analytical and bioanalytical chemistry.

MATERNAL BIOTIN DEFICIENCY CAUSES FETAL MALFORMATIONS BY INDUCING FETAL BIOTIN DEFICIENCY

D. Mock, D. Hansen, N. Mock, 1999 .

In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency.

D. Mock, G. Boysen, A. Bogusiewicz, 2015, Journal of NutriLife.

Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design.

D. Mock, G. Boysen, J. Moran, 2012, The Journal of nutrition.

Evidence for a Pathogenic Role of ω6 Polyunsaturated Fatty Acid in the Cutaneous Manifestations of Biotin Deficiency

D. Mock, 1990, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

Effects of Biotin Deficiency on Plasma and Tissue Fatty Acid Composition: Evidence for Abnormalities in Rats

D. Mock, R. Holman, N. Mock, 1988, Pediatric Research.

Effects of biotin deficiency on serum fatty acid composition: evidence for abnormalities in humans.

D. Mock, R. Holman, S. Johnson, 1988, The Journal of nutrition.

Human and Clinical Nutrition Biotin Status Assessed Longitudinally in Pregnant Women 1 – 4

D. Stadler, D. Mock, N. Mock, 1997 .

Biliary excretion of biotin and biotin metabolites is quantitatively minor in rats and pigs.

J. Zempleni, D. Mock, G. Green, 1997, The Journal of nutrition.

Effect of aging on intestinal biotin transport in the rat

D. Horne, D. Mock, H. Said, 1990, Experimental Gerontology.

Biotin accounts for less than half of all biotin and biotin metabolites in the cerebrospinal fluid of children.

D. Mock, A. Bogusiewicz, S. L. Stratton, 2008, The American journal of clinical nutrition.

Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding.

D. Mock, W. Sealey, A. Teague, 2004, Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems.

Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.

D. Mock, N. Mock, K. S. Wang, 1997, The Journal of nutrition.

Bioavailability of biotin given orally to humans in pharmacologic doses.

J. Zempleni, D. Mock, 1999, The American journal of clinical nutrition.

The pig is an appropriate model for human biotin catabolism as judged by the urinary metabolite profile of radioisotope-labeled biotin.

G. Kearns, D. Mock, K. S. Wang, 1997, The Journal of nutrition.

Concentrations of biotin metabolites in human milk.

D. Mock, N. Mock, S. L. Stratton, 1997, The Journal of pediatrics.

Biotin transport and metabolism in the central nervous system

D. Mock, R. Spector, 1988, Neurochemical Research.

Studies of the reversible binding of biotin to human plasma.

D. Mock, G. Lankford, 1990, The Journal of nutrition.

A study of the interaction of avidin with 2-anilinonaphthalene-6-sulfonic acid as a probe of the biotin binding site.

D. Mock, P. Horowitz, G. Lankford, 1988, Biochimica et biophysica acta.

Growth retardation in chronic inflammatory bowel disease.

D. Mock, 1986, Gastroenterology.

Reply to selected summary: More on biotin deficiency, parenteral alimentation, and lactic acidosis (Gastroenterology 1981;81:1166)

D. Mock, 1982 .

Marginal biotin deficiency is teratogenic.

J. Zempleni, D. Mock, 2000, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

The metabolite profile of radioisotope-labeled biotin in rats indicates that rat biotin metabolism is similar to that in humans.

D. Mock, A. Patel, K. S. Wang, 1996, The Journal of nutrition.

Chronic ethanol feeding and acute ethanol exposure in vitro: effect on intestinal transport of biotin.

D. Mock, H. Said, A. Sharifian, 1990, The American journal of clinical nutrition.

Biotin analysis of commercial vitamin and other nutritional supplements.

D. Mock, N. Tolaymat, 1989, The Journal of nutrition.

Rayon balls and disposable-diaper material selectively adsorb creatinine.

D. Mock, 1992, The American journal of clinical nutrition.

Biotin in human milk: methods, location, and chemical form.

D. Mock, N. Mock, S. E. Langbehn, 1992, The Journal of nutrition.

Secretory patterns of biotin in human milk.

D. Mock, N. Mock, J. A. Dankle, 1992, The Journal of nutrition.

Increased excretion of 3-hydroxyisovaleric acid provides evidence of biotin deficiency during pregnancy

D. Stadler, D. Mock, N. Mock, 1996 .

Evidence that biotin status is impaired in human pregnancy

D. Mock, A. Bogusiewicz, Nell I. Matthews, 2009 .

Abnormal organic aciduria in biotin deficiency: the rat is similar to the human.

S. Weintraub, D. Mock, N. Mock, 1988, The Journal of laboratory and clinical medicine.

Sequential solid-phase assay for biotin based on 125I-labeled avidin.

D. Mock, 1990, Methods in enzymology.

Instability of the biotin-protein bond in human plasma.

D. Mock, Anna Bogusiewicz, Nell I Mock, 2004, Analytical biochemistry.

Accelerated removal of antibody‐coated red blood cells from the circulation is accurately tracked by a biotin label

J. Widness, L. Burmeister, R. Strauss, 2012, Transfusion.

Red blood cell (RBC) volume can be independently determined in vivo in humans using RBCs labeled at different densities of biotin

J. Widness, L. Burmeister, R. Strauss, 2011, Transfusion.

Red blood cell (RBC) volume can be independently determined in vivo in the sheep using ovine RBCs labeled at different densities of biotin

J. Widness, L. Burmeister, R. Strauss, 2010, Transfusion.

Urinary excretion of 3‐hydroxyisovaleryl carnitine (3HIAC) in response to a leucine load increases in marginal biotin deficiency

D. Mock, J. Moran, Thomas D. Horvath, 2011 .

Requirements for biotin are not affected by the combination of copper deficiency and fructose feeding.

D. Mock, N. Mock, M. Fields, 1994, Journal of the American College of Nutrition.

[14C]Cyanate Labeling of Sheep Red Cells: Covalent Binding to Hemoglobin Continues in Vivo for a Day

R. Strauss, D. Mock, G. Lankford, 1997, Pediatric Research.

Pancreatitis and alcoholism disorder the renal tubule and impair reclamation of some low molecular weight proteins.

R. Morris, D. Mock, J. Cello, 1987, Gastroenterology.

Circulating Red Cell Volume and Red Cell Survival Can Be Accurately Determined in Sheep Using the [14C]Cyanate Label

L. Burmeister, R. Strauss, D. Mock, 1997, Pediatric Research.

Posttransfusion 24‐hour recovery and subsequent survival of allogeneic red blood cells in the bloodstream of newborn infants

J. Widness, K. Johnson, R. Strauss, 2004, Transfusion.

In vivo multispectral photoacoustic and photothermal flow cytometry with multicolor dyes: A potential for real‐time assessment of circulation, dye‐cell interaction, and blood volume

Mustafa Sarimollaoglu, Donald Mock, V. Zharov, 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

The Proportion of Mitochondrial Isoenzyme of Aspartate Aminotransferase Is Not Elevated in Reye's Syndrome

D. Mock, M. Thaler, N. Mock, 1983, Pediatric Research.

Hematocrit Correlates Well with Circulating Red Blood Cell Volume in Very Low Birth Weight Infants

E. Bell, J. Widness, D. Mock, 2001, Pediatric Research.

Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing.

J. Widness, R. Ohls, D. Mock, 2017, Journal of pharmaceutical sciences.

Target-mediated disposition population pharmacokinetics model of erythropoietin in premature neonates following multiple intravenous and subcutaneous dosing regimens.

J. Widness, D. Mock, G. An, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A randomized clinical trial comparing immediate versus delayed clamping of the umbilical cord in preterm infants: short‐term clinical and laboratory endpoints

E. Bell, K. Johnson, L. Burmeister, 2008, Transfusion.

A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis

J. Widness, D. Mock, P. Veng‐Pedersen, 2015, The AAPS Journal.

Circulating RBC volume, measured with biotinylated RBCs, is superior to the Hct to document the hematologic effects of delayed versus immediate umbilical cord clamping in preterm neonates

K. Johnson, R. Strauss, D. Mock, 2003, Transfusion.

A biotin-protein bond with stability in plasma.

D. Mock, N. Mock, A. Bogusiewicz, 2005, Analytical biochemistry.

Clearance of stored red blood cells is not increased compared with fresh red blood cells in a human endotoxemia model

J. Widness, D. Mock, N. Juffermans, 2016, Transfusion.

Cholelithiasis in a 2-year-old child with reflux esophagitis and hiatus hernia.

D. Mock, M. Harrison, J. Perman, 1980, The Journal of pediatrics.