Chunmei Gao

发表

Discovery of novel dual VEGFR2 and Src inhibitors using a multistep virtual screening approach.

Yu Yang Jiang, Y. Chen, C. Zhang, 2017, Future medicinal chemistry.

Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors.

F. Liu, Yuyang Jiang, Chunmei Gao, 2018, Bioorganic & medicinal chemistry.

Discovery of ErbB/HDAC inhibitors by combining the core pharmacophores of HDAC inhibitor vorinostat and kinase inhibitors vandetanib, BMS-690514, neratinib, and TAK-285

Yuyang Jiang, Chunmei Gao, Dan Li, 2017 .

Design, synthesis and evaluation of acridine derivatives as multi-target Src and MEK kinase inhibitors for anti-tumor treatment.

Yuzong Chen, Hongxia Liu, Yuyang Jiang, 2016, Bioorganic & medicinal chemistry.

Exposure of CCRF‐CEM cells to acridone derivative 8a triggers tumor death via multiple mechanisms

Dan Gao, Hongxia Liu, Yuyang Jiang, 2016, Proteomics.

Design, synthesis and biological evaluation of novel phthalazinone acridine derivatives as dual PARP and Topo inhibitors for potential anticancer agents

Yuyang Jiang, Chunmei Gao, Qinsheng Sun, 2020 .

One step synthesis of azo compounds from nitroaromatics and anilines

Hongxia Liu, Yuyang Jiang, Chunmei Gao, 2011 .

Synthesis and evaluation of 10-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as selective telomeric G-quadruplex DNA ligands

F. Liu, Yuyang Jiang, Chunmei Gao, 2012 .

Acridine and its derivatives: a patent review (2009 – 2013)

B. Li, Yuyang Jiang, Chunmei Gao, 2014, Expert opinion on therapeutic patents.

Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors.

Yuzong Chen, Hongxia Liu, Yuyang Jiang, 2011, Bioorganic & medicinal chemistry.

Pharmacokinetics and metabolite identification of a novel VEGFR-2 and Src dual inhibitor 6-chloro-2-methoxy-N-(2-methoxybenzyl) acridin-9-amine in rats by liquid chromatography tandem mass spectrometry.

Z. Cai, Hongxia Liu, Yuyang Jiang, 2012, Talanta.

Synthesis of Fréchet-type dendritic homotriptycenes

Wenjie Liu, Yuyang Jiang, Chunmei Gao, 2009 .

New synthetic flavone derivatives induce apoptosis of hepatocarcinoma cells.

Xuyu Zu, Yuyang Jiang, Chunmei Gao, 2010, Bioorganic & medicinal chemistry.

PARP inhibitors as antitumor agents: a patent update (2013-2015)

Yuyang Jiang, Chunmei Gao, Zigao Yuan, 2017, Expert opinion on therapeutic patents.

Novel synthetic acridine-based derivatives as topoisomerase I inhibitors

Hongxia Liu, Yuyang Jiang, Chunmei Gao, 2014 .

Structure Determination of Photoproducts of Anthracenes with (Arylmethoxymethyl) Sidechains

D. Schollmeyer, Chunmei Gao, H. Meier, 2007 .

Molecular design, synthesis and biological research of novel pyridyl acridones as potent DNA-binding and apoptosis-inducing agents.

Yuzong Chen, Hongxia Liu, Yuyang Jiang, 2015, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of a novel platinum(II) complex possessing bioreductive groups for cancer therapy

Yuyang Jiang, Chunmei Gao, Zigao Yuan, 2019, Chinese Chemical Letters.

Optical switching and antenna effect of dendrimers with an anthracene core.

Chunmei Gao, H. Meier, D. Cao, 2007, Chemistry.

Highly sensitive and selective “naked eye” sensing of Cu(II) by a novel acridine-based sensor both in aqueous solution and on the test kit

Yuyang Jiang, Chunmei Gao, Qiuzi Dai, 2018, Tetrahedron.

Novel synthetic 2-amino-10-(3,5-dimethoxy)benzyl-9(10H)-acridinone derivatives as potent DNA-binding antiproliferative agents.

F. Liu, Hongxia Liu, Yuyang Jiang, 2010, Bioorganic & medicinal chemistry.

Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones.

Xuyu Zu, Yuyang Jiang, Chunmei Gao, 2008, Bioorganic & medicinal chemistry.

A POCl3-mediated synthesis of substituted fused azoacridones derivatives

Yuyang Jiang, Chunmei Gao, Bin Zhang, 2015 .

The design, synthesis, and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues.

Xuyu Zu, Hongxia Liu, Yuyang Jiang, 2008, Bioorganic & medicinal chemistry.

Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors.

Yuzong Chen, Hongxia Liu, Yuyang Jiang, 2011, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents.

Hongxia Liu, Yuyang Jiang, Chunmei Gao, 2015, Bioorganic & medicinal chemistry.

Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents.

Yuzong Chen, F. Liu, Hongxia Liu, 2013, Bioorganic & medicinal chemistry.

Competition between Inter- and Intramolecular Photocycloaddition Reactions of 9-Substituted Anthracenes

Chunmei Gao, H. Meier, D. Cao, 2007 .

Protonation and rearrangement of the tricyclo[4.2.2.22,5]dodeca-3,7,9,11-tetraene scaffold

Chunmei Gao, H. Meier, D. Cao, 2006 .

Design and synthesis of N-phosphoryl peptide modified podophyllotoxin derivatives as potent anticancer agents.

Hongxia Liu, Yuyang Jiang, Chunmei Gao, 2011, Protein and peptide letters.

2′‐Chloro‐4′‐aminoflavone Derivatives Selectively Targeting Hepatocarcinoma Cells: Convenient Synthetic Process, G2/M Cell Cycle Arrest and Apoptosis Triggers

F. Liu, Dan Gao, Hongxia Liu, 2012, Archiv der Pharmazie.

A simple benzimidazole quinoline-conjugate fluorescent chemosensor for highly selective detection of Ag+

Hongxia Liu, Yuyang Jiang, Chunmei Gao, 2016 .

Efficient synthesis of RITA and its analogues: derivation of analogues with improved antiproliferative activity via modulation of p53/miR-34a pathway.

Yuyang Jiang, Chunmei Gao, D. Cao, 2012, Organic & biomolecular chemistry.

A one-step synthesized acridine-based fluorescent chemosensor for selective detection of copper(II) ions and living cell imaging

Caizhen Zhu, Yuyang Jiang, Chunmei Gao, 2018 .

Synthesis and antiproliferative activity of RITA and its analogs

Yuyang Jiang, Chunmei Gao, Chunyan Tan, 2014 .

New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway

F. Liu, Yuyang Jiang, Chunmei Gao, 2015, Acta Pharmacologica Sinica.

Acid-catalyzed cyclization of anthracenol derivatives to homotriptycenes.

Chunmei Gao, H. Meier, D. Cao, 2006, The Journal of organic chemistry.

Discovery of 1-(3-aryl-4-chlorophenyl)-3-(p-aryl)urea derivatives against breast cancer by inhibiting PI3K/Akt/mTOR and Hedgehog signalings.

Yuzong Chen, F. Liu, Yuyang Jiang, 2017, European journal of medicinal chemistry.

Phthalimide conjugations for the degradation of oncogenic PI3K.

Yuzong Chen, Yuyang Jiang, Chunmei Gao, 2018, European journal of medicinal chemistry.

Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors.

Yuzong Chen, Yuyang Jiang, Chunmei Gao, 2017, European journal of medicinal chemistry.

Design, synthesis and evaluation of azaacridine derivatives as dual-target EGFR and Src kinase inhibitors for antitumor treatment.

Yuzong Chen, Yuyang Jiang, Chunmei Gao, 2017, European journal of medicinal chemistry.

Acridone Derivative 8a Induces Oxidative Stress-Mediated Apoptosis in CCRF-CEM Leukemia Cells: Application of Metabolomics in Mechanistic Studies of Antitumor Agents

F. Liu, Dan Gao, Hongxia Liu, 2013, PloS one.

Novel multi-substituted benzyl acridone derivatives as survivin inhibitors for hepatocellular carcinoma treatment.

Wei Zhang, Yuzong Chen, F. Liu, 2017, European journal of medicinal chemistry.

Clustered Distribution of Natural Product Leads of Drugs in the Chemical Space as Influenced by the Privileged Target-Sites

Chunmei Gao, Peng Zhang, Chu Qin, 2015, Scientific Reports.

Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy.

Yuzong Chen, Yuyang Jiang, Chunmei Gao, 2019, Bioorganic chemistry.

Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy.

Yuzong Chen, Yuyang Jiang, Chunmei Gao, 2017, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy.

Yuyang Jiang, Chunmei Gao, Qiuzi Dai, 2017, European journal of medicinal chemistry.

Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.

Hongxia Liu, Yuyang Jiang, Chunmei Gao, 2016, European journal of medicinal chemistry.

Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.

Yuzong Chen, Yuyang Jiang, Chunmei Gao, 2017, Bioorganic & medicinal chemistry.

Improving the quantum yields of fluorophores by inhibiting twisted intramolecular charge transfer using electron-withdrawing group-functionalized piperidine auxochromes.

W. Guo, Taihe Han, Chunmei Gao, 2019, Chemical communications.

A Facile Synthesis of Homotriptycenes from Anthranol Derivatives

Chunmei Gao, H. Meier, D. Cao, 2005 .