H. Lemke

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Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

H Stein, H. Stein, J. Gerdes, 1984, Journal of immunology.

Reversal of the adult IgE high responder phenotype in mice by maternally transferred allergen‐specific monoclonal IgG antibodies during a sensitive period in early ontogeny

H. Lemke, H. Hansen, H. Lange, 2002, European journal of immunology.

Antigen‐independent suppression of the IgE immune response to bee venom phospholipase A2 by maternally derived monoclonal IgG antibodies

H. Lemke, H. Hansen, H. Lange, 1998, European journal of immunology.

Isolation of twelve monoclonal antibodies against Ia and H-2 antigens. Serological characterization and reactivity with B and T lymphocytes

G. Hämmerling, U. Hämmerling, H. Lemke, 1979, Immunogenetics.

A zinc metalloproteinase is responsible for the release of cd30 on human tumor cell lines

J. Kobarg, B. Havsteen, H. Lemke, 1995, International journal of cancer.

Shedding of the soluble form of CD30 from the Hodgkin‐analogous cell line L540 is strongly inhibited by a new CD30‐specific antibody (Ki‐4)

M. Tiemann, R. Parwaresch, J. Kobarg, 1995, International Journal of Cancer.

The Hodgkin-associated Ki-1 antigen exists in an intracellular and a membrane-bound form.

B. Havsteen, H. Lemke, H. Hansen, 1989, Biological chemistry Hoppe-Seyler.

Biochemical characterization and biosynthesis of the Ki-1 antigen in Hodgkin-derived and virus-transformed human B and T lymphoid cell lines.

H. Stein, J. Gerdes, P. Froese, 1987, Journal of immunology.

CD30 Shedding from Karpas 299 Lymphoma Cells Is Mediated by TNF-α-Converting Enzyme1

H. Lemke, G. Murphy, R. Mentlein, 2000, The Journal of Immunology.

Development of new ricin A‐chain immunotoxins with potent anti‐tumor effects against human hodgkin cells in vitro and disseminated Hodgkin tumors in scid mice using high‐affinity monoclonal antibodies directed against the CD30 antigen

V. Diehl, R. Parwaresch, H. Lemke, 1995, International journal of cancer.

ADAM17-overexpressing breast cancer cells selectively targeted by antibody–toxin conjugates

S. Rose-John, M. Peipp, A. Trad, 2013, Cancer Immunology, Immunotherapy.

Vitronectin- and fibronectin-containing immune complexes in primary systemic vasculitis.

J. Kobarg, H. Lemke, W. Gross, 2002, Journal of autoimmunity.

Hybrid cell lines secreting monoclonal antibody specific for major histocompatibility antigens of the mouse

K. Rajewsky, G. Hämmerling, H. Lemke, 1978, Nature.

Serological analysis of H-2 and Ia molecules with monoclonal antibodies

J. Klein, G. Hämmerling, U. Hämmerling, 1979, Immunogenetics.

Monoclonal antibodies against murine cell surface antigens: anti-H-2, anti-Ia and anti-T cell antibodies.

K. Rajewsky, G. Hämmerling, U. Hämmerling, 1978, Current topics in microbiology and immunology.

Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cells

V. Diehl, J. Gerdes, H. Lemke, 1982, Nature.

Identification of Hodgkin and sternberg‐reed cells as a unique cell type derived from a newly‐detected small‐cell population

V. Diehl, J. Gerdes, D. Mason, 1982, International journal of cancer.

The role of fetal calf serum in the primary immune response in vitro

H. Flad, H. Lemke, W. Schreml, 1977, The Journal of experimental medicine.

The Role of Adherent Cells in the Immune Response

H. Lemke, G. Möller, H. Opitz, 1976, Scandinavian journal of immunology.

Macrophages Suppress Direct B‐Cell Activation by Lipopolysaccharide

A. Coutinho, H. Lemke, H. Opitz, 1975, Scandinavian journal of immunology.

Isolation of a cloned cell line expressing variant H–2Kk using fluorescence-activated cell sorting

K. Rajewsky, M. Cramer, H. Lemke, 1981, Nature.

An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETÁ) is a potent immunotoxin against a Hodgkin-derived cell line

V. Diehl, J. Arends, R. Roovers, 1999, British Journal of Cancer.

Enzyme -Converting a Cells Is Mediated by TNF-CD30 Shedding from Karpas 299 Lymphoma

H. Lemke, G. Murphy, R. Mentlein, 2000 .

Evidence for the detection of the normal counterpart of hodgkin and sternberg‐reed cells

V. Diehl, H. Stein, J. Gerdes, 2007, Hematological oncology.

Growth regulation of a murine lymphoma cell line by a 2‐mercaptoethanol or macrophage‐activated serum factor

H. Lemke, G. Hewlett, H. Schlumberger, 1977, European journal of immunology.

CD30 shedding from Karpas 299 lymphoma cells is mediated by TNF-alpha-converting enzyme.

H. Lemke, G. Murphy, R. Mentlein, 2000, Journal of immunology.

Inhibition of metalloproteinases enhances the internalization of anti‐CD30 antibody Ki‐3 and the cytotoxic activity of Ki‐3 immunotoxin

S. Barth, H. Lemke, A. Engert, 2002, International journal of cancer.

Evidence of Sternberg-Reed cells being derived from activated lymphocytes.

H. Stein, J. Gerdes, D. Mason, 1985, Haematology and blood transfusion.

Biochemical characterization of a factor released by macrophages.

R. Jackson, H. Flad, H. Lemke, 1975, Cellular immunology.

Cellular localizations and processing of the two molecular forms of the Hodgkin-associated Ki-1 (CD30) antigen. The protein kinase Ki-1/57 occurs in the nucleus.

M. Hafner, H. Lemke, V. Mielke, 1992, The American journal of pathology.

Two Trans-sialidase Forms with Different Sialic Acid Transfer and Sialidase Activities from Trypanosoma congolense*

J. Tiralongo, E. Tiralongo, H. Lemke, 2003, Journal of Biological Chemistry.

No histocompatibility requirements for macrophage-lymphocyte interactions in the primary immune antibody response to sheep erythrocytes in vitro

A. Coutinho, H. Lemke, G. Möller, 1976 .

Evidence for the origin of Hodgkin and Sternberg-Reed cells from a newly detected small cell population.

V. Diehl, H. Stein, J. Gerdes, 1983, Haematology and blood transfusion.

Immune Response Regulation by Antigen Receptors’ Clone-Specific Nonself Parts

H. Lemke, 2018, Front. Immunol..

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

Johannes Gerdes, H. Stein, J. Gerdes, 1983, International journal of cancer.

Growth fractions in malignant non‐Hodgkin's lymphomas (NHL) as determined in situ with the monoclonal antibody Ki‐67

K. Lennert, H. Stein, J. Gerdes, 1984, Hematological oncology.

Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

H. Lemke, U. Hámmerling, G. Hámmerling, 1979, Immunological reviews.

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells.

K. Lennert, H. Stein, J. Gerdes, 1985, Blood.

Protein kinase activity of the intracellular but not of the membrane-associated form of the Ki-1 antigen (CD30).

B. Havsteen, H. Lemke, H. Hansen, 1990, Research in immunology.

Humoral primary immune response in vitro in a homologous mouse system: replacement of fetal calf serum by a 2-mercaptoethanol or macrophage-activated fraction of mouse serum.

H. Flad, H. Lemke, U. Opitz, 1977, Journal of immunology.

Inhibition of killer‐target cell interaction by monoclonal anti‐H‐2 antibodies

K. F. Lindahl, H. Lemke, K. Lindahl, 1979, European journal of immunology.

Inhibition of 3H-thymidine incorporation of lymphocytes by a soluble factor from macrophages.

H. Flad, H. Lemke, D. Niethammer, 1975, Cellular immunology.

Thymus-independent type 2 antigen induces a long-term IgG-related network memory.

A. Trad, H. Lemke, M. Zemlin, 2008, Molecular immunology.

Correlation between immune maturation and idiotypic network recognition

C. Berek, H. Lemke, H. Lange, 1996, European journal of immunology.

Generalization of single immunological experiences by idiotypically mediated clonal connections.

H. Lemke, H. Lange, 2002, Advances in immunology.

Benefits and burden of the maternally-mediated immunological imprinting.

A. Trad, H. Lemke, H. Lange, 2009, Autoimmunity reviews.

Function of Maternal Idiotypic and Anti-idiotypic Antibodies as Transgenerational Messengers

A. Trad, H. Lemke, H. Lange, 2012 .

Lamarckian inheritance by somatically acquired maternal IgG phenotypes.

A. Coutinho, H. Lemke, H. Lange, 2004, Trends in immunology.

Non-genetic inheritable potential of maternal antibodies.

H. Lemke, H. Hansen, H. Lange, 2003, Vaccine.

Function of 2-mercaptoethanol as a macrophage substitute in the primary immune response in vitro.

H. Lemke, H. Opitz, Hilmar Lemke, 1976, Journal of immunology.

Polyclonal stimulation of lymphocytes by macrophages

H. Flad, H. Lemke, U. Opitz, 1976, European journal of immunology.

Clustering of antigenic determinants on H-2 molecules.

H. Lemke, G. Hammerling, 1982, Journal of immunology.

Activation of T‐Cells by a Macrophage or 2‐Mercaptoethanol Activated Serum Factor is Essential for Induction of a Primary Immune Response to Heterologous Red Cells in vitro

H. Lemke, G. Hewlett, H. Opitz, 1978, Immunological reviews.

Soluble CD30 plasma concentrations correlate with disease activity in patients with atopic dermatitis.

M. Weichenthal, H. Lemke, E. Christophers, 2002, Acta dermato-venereologica.

Clonal Progression during the T Cell-Dependent B Cell Antibody Response Depends on the Immunoglobulin DH Gene Segment Repertoire

A. Trad, H. Lemke, M. Zemlin, 2014, Front. Immunol..

Quality control of Bacillus thuringiensis ssp. israelensis products based on toxin quantification with monoclonal antibodies

H. Lemke, R. Ehlers, O. Strauch, 2007 .

Maternal immunization modulates the primary immune response to 2‐phenyl‐oxazolone in BALB/c mice

C. Berek, H. Lemke, Hans Lange, 1994, European journal of immunology.

A new phagemid vector for positive selection of recombinants based on a conditionally lethal barnase gene

S. Deyev, H. Lemke, H. Lange, 1999, FEBS Letters.

Idiotype Network

H. Lemke, 2005 .

Maternal antibodies' role in immunity

H. Lemke, 2017, Science.

Soluble CD 30 Plasma Concentrations Correlate with Disease Activity in Patients with Atopic Dermatitis

M. Weichenthal, H. Lemke, E. Christophers, 2002 .

MATERNAL IMMUNOLOGICAL EXPERIENCE GUIDES THE EDUCATION OF THE NEONATAL IMMUNE SYSTEM

J. Kobarg, H. Lemke, S. Yazynin, 2003 .

Rapid and simple purification of PCR products by direct band elution during agarose gel electrophoresis.

H. Lemke, H. Hansen, U. Bodner, 1993, BioTechniques.

Molecular cloning and characterization of human kinectin.

H. Lemke, M. Krönke, G. Kruppa, 1995, Molecular biology of the cell.

Ectodomain shedding of CD30 is specifically regulated by peptide motifs in its cysteine‐rich domains 2 and 5

U. Reineke, H. Lemke, P. Borchmann, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Allergen IgE‐isotype‐specific suppression by maternally derived monoclonal anti‐IgG‐idiotype

A. Trad, J. Grötzinger, H. Lemke, 2010, Allergy.

Induction of a non-oscillating, long-lasting humoral immune response to an internal network antigen.

H. Lemke, H. Lange, 1996, International immunology.

Immunoglobulin class switching appears to be regulated by B‐cell antigen receptor‐specific T‐cell action

A. Trad, H. Lemke, M. Zemlin, 2012, European journal of immunology.

Mycoplasma infection of cell lines can simulate the expression of Fc receptors by binding of the carbohydrate moiety of antibodies

B. Havsteen, H. Lemke, J. Lorenzen, 1985, European journal of immunology.

An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line.

V. Diehl, J. Arends, R. Roovers, 1999, British journal of cancer.

Is There a Maternally Induced Immunological Imprinting Phase à la Konrad Lorenz?

Lange, H. Lemke, Lemke, 1999, Scandinavian journal of immunology.

Hodgkin’s Disease and So-Called Malignant Histiocytosis:

V. Diehl, H. Stein, J. Gerdes, 1984 .

Determination of cell-bound Fc receptors using a cell adherence test (CAT).

H. Lemke, H. Hansen, G. Huss, 1989, Journal of immunological methods.

Techniques for Characterization of Leucocyte Antigens and Utilization of Antibodies in Therapy

H. Tanke, J. Ploem, K. Lennert, 1984 .