W. Lai

发表

Interactions of CCCH Zinc Finger Proteins with mRNA

P. Blackshear, J. M. Thorn, W. Lai, 2000, The Journal of Biological Chemistry.

Tristetraprolin and Its Family Members Can Promote the Cell-Free Deadenylation of AU-Rich Element-Containing mRNAs by Poly(A) Ribonuclease

P. Blackshear, W. Lai, E. Kennington, 2003, Molecular and Cellular Biology.

Interactions of CCCH Zinc Finger Proteins with mRNA

P. Blackshear, W. Lai, 2001, The Journal of Biological Chemistry.

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.

B. Haynes, P. Blackshear, H. Broxmeyer, 1996, Immunity.

Characteristics of the Interaction of a Synthetic Human Tristetraprolin Tandem Zinc Finger Peptide with AU-rich Element-containing RNA Substrates*

G. M. Wilson, P. Blackshear, G. Brewer, 2003, Journal of Biological Chemistry.

Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli

P. Blackshear, D. Zeldin, W. Lai, 2015, Journal of leukocyte biology.

Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages

P. Blackshear, J. Pedrosa, A. G. Castro, 2013, European journal of immunology.

Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin

P. Blackshear, N. Sonenberg, B. Nagar, 2013, Nature Structural &Molecular Biology.

Life without TTP: apparent absence of an important anti-inflammatory protein in birds.

D. Stumpo, P. Blackshear, James M. Ward, 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

Inflammation: cytokines and RNA‐based regulation

D. Stumpo, P. Blackshear, W. Lai, 2010, Wiley interdisciplinary reviews. RNA.

Stimulation of Polo-Like Kinase 3 mRNA Decay by Tristetraprolin

D. Stumpo, P. Blackshear, W. Lai, 2009, Molecular and Cellular Biology.

Novel mRNA Targets for Tristetraprolin (TTP) Identified by Global Analysis of Stabilized Transcripts in TTP-Deficient Fibroblasts

Joel S. Parker, D. Stumpo, P. Blackshear, 2006, Molecular and Cellular Biology.

Tandem CCCH Zinc Finger Proteins in mRNA Binding

P. Blackshear, W. Lai, R. S. Phillips, 2005 .

The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis

P. Blackshear, W. Lai, D. Carrick, 2004, Arthritis research & therapy.

CHAPTER 317 – Regulation of mRNA Turnover

P. Blackshear, W. Lai, 2003 .

Decreased Sensitivity of Tristetraprolin-deficient Cells to p38 Inhibitors Suggests the Involvement of Tristetraprolin in the p38 Signaling Pathway*

P. Blackshear, W. Lai, E. Carballo, 2001, The Journal of Biological Chemistry.

Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability.

P. Blackshear, W. Lai, E. Carballo, 2000, Blood.

Identification of four CCCH zinc finger proteins in Xenopus, including a novel vertebrate protein with four zinc fingers and severely restricted expression.

P. Blackshear, X. Liu, J. M. Thorn, 1999, Gene.

Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein.

D. Stumpo, P. Blackshear, W. Lai, 1990, The Journal of biological chemistry.

The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes.

R. Eddy, T. Shows, P. Blackshear, 1991, Nucleic acids research.

Mitogens stimulate the rapid nuclear to cytosolic translocation of tristetraprolin, a potential zinc-finger transcription factor.

P. Blackshear, W. Lai, G. Taylor, 1996, Molecular endocrinology.

Interaction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression.

J. Jauniaux, P. Blackshear, A. Burny, 2003, Journal of the National Cancer Institute.

Beta-hydroxybutyrate dampens adipose progenitors’ profibrotic activation through canonical Tgfβ signaling and non-canonical ZFP36-dependent mechanisms

K. Clément, Nataliya Sokolovska, P. Blackshear, 2022, Molecular metabolism.

Effect of aging on the interaction of quinuclidinyl benzilate, N-methylscopolamine, pirenzepine, and gallamine with brain muscarinic receptors

W. Lai, E. El-Fakahany, N. H. Lee, 1988, Neurochemical Research.

CALL FOR PAPERS Integrative and Translational Physiology: Inﬂammation and Immunity in Organ System Physiology Life without TTP: apparent absence of an important anti-inﬂammatory protein in birds

D. Stumpo, P. Blackshear, James M. Ward, 2013 .

Influence of Nonameric AU-rich Tristetraprolin-binding Sites on mRNA Deadenylation and Turnover*

P. Blackshear, W. Lai, D. Carrick, 2005, Journal of Biological Chemistry.

A post-transcriptional regulon controlled by TtpA, the single tristetraprolin family member expressed in Dictyostelium discoideum.

Stephanie N. Hicks, P. Blackshear, L. Perera, 2021, Nucleic acids research.

Cathepsin D as a new allergen from Dermatophagoides farinae

Xiaoyu, Desheng Chen, Chengshen Hu, 2018 .

Transgenic complementation of MARCKS deficiency with a nonmyristoylatable, pseudo-phosphorylated form of MARCKS: evidence for simultaneous positive and dominant-negative effects on central nervous system development.

H. S. Kim, P. Blackshear, W. Lai, 1998, Developmental biology.

Neuronal muscarinic responses: role of protein kinase C

P. Worley, J. Baraban, B. Alger, 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Interactions of CCCH Zinc Finger Proteins with mRNA

P. Blackshear, W. Lai, E. Kennington, 2002, The Journal of Biological Chemistry.

Multiple binding affinities of N-methylscopolamine to brain muscarinic acetylcholine receptors: differentiation from M1 and M2 receptor subtypes.

W. Lai, V. Ramkumar, E. El-Fakahany, 1986, The Journal of pharmacology and experimental therapeutics.

Possible Allosteric Interaction of 4‐Aminopyridine with Rat Brain Muscarinic Acetylcholine Receptors

W. Lai, V. Ramkumar, E. El-Fakahany, 1985, Journal of neurochemistry.

Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin

P. Blackshear, W. Lai, E. Carballo, 1998 .

Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth.

P. Blackshear, W. Lai, G. Taylor, 1996, Gene.

Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA

P. Blackshear, B. Spencer‐Dene, D. Zecchin, 2017, Immunity.

Characteristics of the Intron Involvement in the Mitogen-induced Expression of Zfp-36 *

M. Thompson, P. Blackshear, W. Lai, 1998, The Journal of Biological Chemistry.

Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover.

P. Blackshear, W. Lai, René M. Arvola, 2019, Methods.

The NIEHS Xenopus maternal EST project: interim analysis of the first 13,879 ESTs from unfertilized eggs.

P. Blackshear, G. Bouffard, M. Soares, 2001, Gene.

Evidence that Tristetraprolin Binds to AU-Rich Elements and Promotes the Deadenylation and Destabilization of Tumor Necrosis Factor Alpha mRNA

P. Blackshear, W. Lai, E. Carballo, 1999, Molecular and Cellular Biology.

Emergence and evolution of Zfp36l3.

D. Stumpo, P. Blackshear, W. Lai, 2016, Molecular phylogenetics and evolution.

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

P. Blackshear, W. Lai, E. Carballo, 1998, Science.

The tandem zinc finger RNA binding domain of members of the tristetraprolin protein family

P. Blackshear, L. Perera, W. Lai, 2019, Wiley interdisciplinary reviews. RNA.

A Knock-In Tristetraprolin (TTP) Zinc Finger Point Mutation in Mice: Comparison with Complete TTP Deficiency

D. Stumpo, P. Blackshear, R. Faccio, 2017, Molecular and Cellular Biology.

The Drosophila Tis11 Protein and Its Effects on mRNA Expression in Flies*

G. M. Wilson, D. Stumpo, P. Blackshear, 2014, The Journal of Biological Chemistry.

Mutational and Structural Analysis of the Tandem Zinc Finger Domain of Tristetraprolin*

P. Blackshear, L. Perera, W. Lai, 2013, The Journal of Biological Chemistry.

Tristetraprolin Tandem Zinc Finger Domain of Mutational and Structural Analysis of the RNA

P. Blackshear, L. Perera, W. Lai, 2013 .

Zfp36l3, a Rodent X Chromosome Gene Encoding a Placenta-Specific Member of the Tristetraprolin Family of CCCH Tandem Zinc Finger Proteins

E. Richfield, P. Blackshear, S. Ramos, 2005, Biology of reproduction.

Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38MAPK/MK2 Cascade1

P. Blackshear, M. Gaestel, P. Heinrich, 2007, The Journal of Immunology.

Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies

Alan D. Curtis, D. Stumpo, P. Blackshear, 2016, Proceedings of the National Academy of Sciences.

Control of cytokine mRNA degradation by the histone deacetylase inhibitor ITF2357 in rheumatoid arthritis fibroblast-like synoviocytes: beyond transcriptional regulation

P. Blackshear, T. Radstake, D. Baeten, 2018, Arthritis Research & Therapy.

Phosphorylation of Tristetraprolin, a Potential Zinc Finger Transcription Factor, by Mitogen Stimulation in Intact Cells and by Mitogen-activated Protein Kinase in Vitro(*)

M J Thompson, M. Thompson, P. Blackshear, 1995, The Journal of Biological Chemistry.

Promoter Analysis of Zfp-36, the Mitogen-inducible Gene Encoding the Zinc Finger Protein Tristetraprolin (*)

M. Thompson, P. Blackshear, W. Lai, 1995, The Journal of Biological Chemistry.

Mouse Embryonic Fibroblast Cell Culture and Stimulation.

D. Stumpo, P. Blackshear, W. Lai, 2016, Bio-protocol.

Measurement of mRNA Decay in Mouse Embryonic Fibroblasts.

D. Stumpo, P. Blackshear, W. Lai, 2016, Bio-protocol.

Importance of the Conserved Carboxyl-Terminal CNOT1 Binding Domain to Tristetraprolin Activity In Vivo

Stephanie N. Hicks, D. Stumpo, P. Blackshear, 2019, Molecular and Cellular Biology.

Promoter sequence, expression, and fine chromosomal mapping of the human gene (MLP) encoding the MARCKS-like protein: identification of neighboring and linked polymorphic loci for MLP and MACS and use in the evaluation of human neural tube defects.

A. Dehejia, M. Polymeropoulos, D. Stumpo, 1998, Genomics.

Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency.

A. Nairn, D. Stumpo, P. Blackshear, 1996, Brain research. Developmental brain research.

Interaction of 4-aminopyridine with [3H]phencyclidine receptors in rat brain homogenates

W. Lai, E. El-Fakahany, 1986, Neuroscience Letters.

Evidence that Tristetraprolin Binds to AU-Rich Elements and Promotes the Deadenylation and Destabilization of Tumor Necrosis Factor Alpha mRNA

P. Blackshear, W. Lai, E. Carballo, 1999, Molecular and Cellular Biology.

Synergistic roles of tristetraprolin family members in myeloid cells in the control of inflammation

W. Lai, Brittany L Snyder, P J Blackshear, 2023, Life Science Alliance.