K. Spriggs

发表

Translational regulation of gene expression during conditions of cell stress.

M. Bushell, A. Willis, K. Spriggs, 2010, Molecular cell.

Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry.

R. Spriggs, J. L. Le Quesne, M. Bushell, 2005, Genes & development.

Internal ribosome entry segment-mediated translation during apoptosis: the role of IRES-trans-acting factors

M. Bushell, A. Willis, K. Spriggs, 2005, Cell Death and Differentiation.

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein.

M. Bushell, A. Willis, K. Spriggs, 2008, Biochemical Society transactions.

The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

Yi Wen Kong, Anne E Willis, H. Meijer, 2008, Proceedings of the National Academy of Sciences.

PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs

Franco H Falcone, K. Spriggs, H. Collins, 2013, PloS one.

eIF4A Inhibition Allows Translational Regulation of mRNAs Encoding Proteins Involved in Alzheimer's Disease

A. Willis, K. Spriggs, T. E. Webb, 2010, PloS one.

Functionalized Block Co‐Polymer Pro‐Drug Nanoparticles with Anti‐Cancer Efficacy in 3D Spheroids and in an Orthotopic Triple Negative Breast Cancer Model

C. Alexander, A. Grabowska, P. Clarke, 2020, Advanced Therapeutics.

Interactions between helicase and primase are crucial for DNA replication in the enteropathogen Clostridium difficile

W. Smits, K. Spriggs, Annemieke H. Friggen, 2016, bioRxiv.

Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile

W. Smits, K. Spriggs, Annemieke H. Friggen, 2016, Open Biology.

Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery

C. Alexander, S. Stolnik, M. Soliman, 2018, Journal of Interdisciplinary Nanomedicine.

Matthew and Friggen, Annemieke H. and Larson, Marilynn A. and Spriggs, Keith and Briggs, Geoffrey S. and Soultanas, Panos and Smits, Wiep Klaas (2016) Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen

W. Smits, K. Spriggs, Annemieke, 2017 .

SF2/ASF TORCs up translation.

M. Bushell, A. Willis, K. Spriggs, 2008, Molecular cell.

Regulation of BAG-1 IRES-mediated translation following chemotoxic stress

M. Bushell, A. Willis, C. H. Moor, 2008, Oncogene.

Identification of Internal Ribosome Entry Segment (IRES)-trans-Acting Factors for the Myc Family of IRESs

K. Lilley, M. Bushell, C. Hayes, 2007, Molecular and Cellular Biology.

Implications of differential transcription start site selection on chronic myeloid leukemia and prostate cancer cell protein expression

C. Ufer, C. Polytarchou, K. Spriggs, 2022, iScience.

Polypyrimidine tract binding protein regulates IRES-mediated gene expression during apoptosis.

Yi Wen Kong, Anne E Willis, P. Sarnow, 2006, Molecular cell.

TOPs and their regulation.

M. Bushell, K. Spriggs, M. Stoneley, 2006, Biochemical Society transactions.

L-Myc protein synthesis is initiated by internal ribosome entry.

Anne E Willis, Catherine L Jopling, C. Jopling, 2004, RNA.

Dysregulation of protein synthesis and disease

M. Bushell, A. Willis, K. Spriggs, 2010, The Journal of pathology.

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

Alexander Kondrashov, Anne E Willis, Timothy W Gant, 2009, Genes & development.

Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1

M. Bushell, A. Willis, K. Spriggs, 2010, Oncogene.

Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo

Anne E Willis, Jerzy Ostrowski, Karol Bomsztyk, 2003, Oncogene.

Re‐programming of translation following cell stress allows IRES‐mediated translation to predominate

M. Bushell, A. Willis, K. Spriggs, 2008, Biology of the cell.

The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr.

Anne E Willis, Richard J Jackson, R. Jackson, 2003, Molecular cell.

An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression

K. Spriggs, T. E. Webb, D. Smalley, 2015, Oncogenesis.

The human insulin receptor mRNA contains a functional internal ribosome entry segment

Anne E. Willis, Simon H. Ridley, K. Siddle, 2009, Nucleic acids research.

Canonical Initiation Factor Requirements of the Myc Family of Internal Ribosome Entry Segments

M. Bushell, C. Jopling, A. Willis, 2009, Molecular and Cellular Biology.

Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia

P. McEwan, J. Emsley, K. Spriggs, 2010, Molecular Cancer.

Investigation of interactions of polypyrimidine tract-binding protein with artificial internal ribosome entry segments.

A. Willis, K. Spriggs, S. Mitchell, 2005, Biochemical Society transactions.

Cytotoxic potential of ethanol extract of Parquetina nigrescens on MCF-7, C4-2WT, HT 29 and HTC 116 cell lines

T. Bradshaw, K. Spriggs, C. Agyare, 2018 .

Bioreducible cross-linked core polymer micelles enhance in vitro activity of methotrexate in breast cancer cells.

S. Howdle, C. Alexander, C. Jérôme, 2017, Biomaterials science.

Investigating the intracellular effects of hyperbranched polycation-DNA complexes on lung cancer cells using LC-MS-based metabolite profiling.

A. Ghaemmaghami, C. Alexander, S. Stolnik, 2019, Molecular omics.

Ethyl Acetate Extract of Senna alata (L) Roxb Increases Cytotoxicity in the Human Breast, Prostate and Colorectal Cancer Cells

T. Bradshaw, K. Spriggs, B. Onyegeme-okerenta, 2018 .

Segments the Myc Family of Internal Ribosome Entry Canonical Initiation Factor Requirements of

M. Bushell, C. Jopling, A. Willis, 2017 .

The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape

E Provenzano, C Caldas, J Miller, 2015, Cell Death and Disease.

Bag-1 Internal Ribosome Entry Segment Activity Is Promoted by Structural Changes Mediated by Poly(rC) Binding Protein 1 and Recruitment of Polypyrimidine Tract Binding Protein 1

Anne E. Willis, A. Willis, K. Spriggs, 2004, Molecular and Cellular Biology.

Water Solubility Enhancement of Pyrazolo[3,4-d]pyrimidine Derivatives via Miniaturized Polymer-Drug Microarrays.

F. Musumeci, S. Schenone, Nishant Singh, 2018, ACS Medicinal Chemistry Letters.

Canonical Initiation Factor Requirements of the Myc Family of Internal Ribosome Entry Segments

M. Bushell, C. Jopling, A. Willis, 2009, Molecular and Cellular Biology.

Journal Pre-proof Implications of differential Transcription Start Site selection on CML and prostate cancer cell protein expression

K. Spriggs, A. Surani, Christoph Ufer, 2022 .

Journal Pre-proof Implications of differential Transcription Start Site selection on CML and prostate cancer cell protein expression

K. Spriggs, C. Montiel-Duarte, A. Surani, 2022 .