M. Asselin

发表

Quantifying heterogeneity in human tumours using MRI and PET.

N. Thacker, R. Boellaard, A. Jackson, 2012, European journal of cancer.

Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study.

P. McGuire, P. Grasby, O. Howes, 2010, Archives of general psychiatry.

Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives.

A. Jackson, G. Parker, G. Jayson, 2008, The Lancet. Oncology.

Elevated striatal dopamine function linked to prodromal signs of schizophrenia.

Marie-Claude Asselin, Lucia Valmaggia, Matthew Broome, 2009, Archives of general psychiatry.

Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis

P. McGuire, P. Mcguire, P. Grasby, 2011, Molecular Psychiatry.

Comparison of HRRT and HR+ Scanners for Quantitative (R)-[11C]verapamil, [11C]raclopride and [11C]flumazenil Brain Studies

Floris H. P. van Velden, Ronald Boellaard, Adriaan A. Lammertsma, 2015, Molecular Imaging and Biology.

Optimization of the Injected Activity in Dynamic 3D PET: A Generalized Approach Using Patient-Specific NECs as Demonstrated by a Series of 15O-H2O Scans

Julian C Matthews, Marie-Claude Asselin, Terry Jones, 2009, Journal of Nuclear Medicine.

Hydration status assessed by multi-frequency bioimpedance analysis.

O. Bar-or, F. McNeill, S. Kriemler, 1998, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Upregulation of opioid receptor binding following spontaneous epileptic seizures.

Alexander Hammers, Marie-Claude Asselin, John S Duncan, 2007, Brain : a journal of neurology.

Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue

D. Mann, M. Kassiou, A. Jacobs, 2020, Theranostics.

PCSK9 impedes hepatitis C virus infection in vitro and modulates liver CD81 expression

A. Prat, N. Seidah, Nasha Nassoury, 2009, Hepatology.

The Regulated Cell Surface Zymogen Activation of the Proprotein Convertase PC5A Directs the Processing of Its Secretory Substrates*

N. Seidah, M. Tang, J. Hamelin, 2008, Journal of Biological Chemistry.

Maximizing model parameter precision by optimizing dose in 3D [15O]H2O PET scans

P. Price, P. Julyan, T. Jones, 2008, 2008 IEEE Nuclear Science Symposium Conference Record.

32nd International Austrian Winter Symposium

V. M. Jerkovic, D. Georg, D. Popović, 2016, EJNMMI Research.

Repeatability of quantitative 18F-FLT uptake measurements in solid tumors: an individual patient data multi-center meta-analysis

R. Boellaard, A. Jackson, E. Jansma, 2018, European Journal of Nuclear Medicine and Molecular Imaging.

Early reduction in tumour [18F]fluorothymidine (FLT) uptake in patients with non-small cell lung cancer (NSCLC) treated with radiotherapy alone

C. Faivre-Finn, F. Blackhall, A. Jackson, 2014, European Journal of Nuclear Medicine and Molecular Imaging.

Experimental validation of estimated spatially variant radioisotope-specific point spread functions using published positron range simulations and fluorine-18 measurements

P. Julyan, J. Matthews, M. Asselin, 2018, Physics in medicine and biology.

ZYMOGEN CLEAVAGE AND EFFECTS ON THE LOW DENSITY LIPOPROTEIN (LDL) RECEPTOR AND LDL CHOLESTEROL

A. Prat, N. Seidah, D. Rader, 2004 .

Proprotein Convertase PC7 Enhances the Activation of the EGF Receptor Pathway through Processing of the EGF Precursor*

N. Seidah, S. Benjannet, C. Lazure, 2011, The Journal of Biological Chemistry.

Thrombin activation of protein C requires prior processing by a liver proprotein convertase

A. Prat, N. Seidah, A. Chamberland, 2017, The Journal of Biological Chemistry.

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Can Mediate Degradation of the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)

A. Prat, N. Seidah, M. Asselin, 2013, PloS one.

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other*

A. Prat, N. Seidah, Y. Jacob, 2015, The Journal of Biological Chemistry.

Proprotein convertase subtilisin/Kexin type 9 (PCSK9) single domain antibodies are potent inhibitors of low density lipoprotein receptor degradation.

A. Prat, N. Seidah, J. Hamelin, 2016, Journal of Biological Chemistry.

Deferoxamine stimulates LDLR expression and LDL uptake in HepG2 cells.

N. Seidah, R. Essalmani, Delia Susan-Resiga, 2016, Molecular nutrition & food research.

Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10*

Annik Prat, Daniel Constam, Marie-Claude Asselin, 2011, The Journal of Biological Chemistry.

Comparison of methods for quantification of rCBF on the HRRT PET scanner using [15O]H2O

M. Koepp, J. Matthews, M. Walker, 2010, IEEE Nuclear Science Symposuim & Medical Imaging Conference.

EFFECT OF P-GP INHIBITION IN DRUG-RESISTANT TLE USING A SINGLE-DOSE OF TARIQUIDAR

Sm Sisodiya, John S. Duncan, Matthias J. Koepp, 2009 .

Definition of a reference region for PET [C-11]diprenorphine studies

Alexander Hammers, Matthias J. Koepp, Vincent J. Cunningham, 2003 .

Correlation of memory function with binding of [C-11]CNS 5161, a novel putative NMDA ion channel PET ligand

Turton, D. Brooks, S. Luthra, 2004 .

Initial kinetic analyses of the in vivo binding of the putative NMDA receptor ligand [C-11]CNS 5161 in humans

D. Brooks, S. Osman, A. Hammers, 2004 .

S.07.07 The pre-synaptic dopaminergic system before and after the onset of psychosis: initial results

R. Murray, P. McGuire, P. Grasby, 2006, European Neuropsychopharmacology.

Measurement of Methylphenidate-Induced Change in Extrastriatal Dopamine Concentration using [11C]FLB 457 PET

Lars Farde, Marie-Claude Asselin, Andrew J Montgomery, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Parametric mapping of [C-11]FLB457 binding using spectral analysis

P. Grasby, M. Asselin, A. Montgomery, 2006, NeuroImage.

The effect of aromatic fluorine substitution in l-DOPA on the in vivo behaviour of [18F]2-, [18F]5- and [18F]6-fluoro-l-DOPA in the human brain☆

C. Nahmias, M. Asselin, N. Vasdev, 2002 .

Evidence for endogenous opioid release in the amygdala during positive emotion

A. Hammers, M. J. Koepp, A. D. Lawrence, 2009, NeuroImage.

18F-FLT PET imaging of cellular proliferation in pancreatic cancer.

P. Manoharan, A. Lamarca, J. Valle, 2016, Critical reviews in oncology/hematology.

Targeting Hypoxia to Improve Non–Small Cell Lung Cancer Outcome

P. Lambin, C. Faivre-Finn, C. West, 2018, Journal of the National Cancer Institute.

In vivo methods for imaging blood–brain barrier function and dysfunction

I. Schiessl, R. Hinz, S. Allan, 2022, European Journal of Nuclear Medicine and Molecular Imaging.

The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation

N. Seidah, R. S. Kiss, Z. Awan, 2016, The Journal of Biological Chemistry.

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

N. Seidah, M. Lindholm, Joacim Elmén, 2010, PloS one.

Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non–small Cell Lung Cancer

Adam K. Featherstone, G. Parker, R. Bristow, 2019, Clinical Cancer Research.

NARC-1/PCSK9 and Its Natural Mutants

A. Prat, N. Seidah, D. Rader, 2004, Journal of Biological Chemistry.

Cell Death, Inflammation, Tumor Burden, and Proliferation Blood Biomarkers Predict Lung Cancer Radiotherapy Response and Correlate With Tumor Volume and Proliferation Imaging

C. Faivre-Finn, C. Dive, F. Blackhall, 2017, Clinical lung cancer.

Bias in iterative reconstruction of low-statistics PET data: benefits of a resolution model

Julian C. Matthews, Peter S. Talbot, Terry Jones, 2009, 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC).

The meaning, measurement and modification of hypoxia in the laboratory and the clinic.

K. Williams, E. Hammond, M. Asselin, 2014, Clinical oncology (Royal College of Radiologists (Great Britain)).

Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes*

A. Prat, N. Seidah, D. Constam, 2013, The Journal of Biological Chemistry.

Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation

A. Prat, N. Seidah, R. Parker, 2009, The Journal of Biological Chemistry.

Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors

Philip Lewis, A. Woolf, S. Kimber, 2018, Stem cell reports.

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation*

A. Prat, N. Seidah, J. Hamelin, 2016, The Journal of Biological Chemistry.

P-glycoprotein Expression and Pharmacoresistant Epilepsy: Cause or Consequence?

S. Sisodiya, M. Thom, J. Duncan, 2014 .

Quantification of [11C]GB67 binding to cardiac α1-adrenoceptors with positron emission tomography: validation in pigs

Susan P. Hume, Marie-Claude Asselin, Paolo G. Camici, 2008, European Journal of Nuclear Medicine and Molecular Imaging.

The role of opioids in restless legs syndrome: an [11C]diprenorphine PET study.

Alexander Hammers, Walter Paulus, Federico Turkheimer, 2005, Brain : a journal of neurology.

P‐glycoprotein overactivity in epileptogenic developmental lesions measured in vivo using (R)‐[11C]verapamil PET

S. Sisodiya, J. Duncan, M. Koepp, 2020, Epilepsia.

Effects of the Prosegment and pH on the Activity of PCSK9

N. Seidah, R. Parker, S. Benjannet, 2010, The Journal of Biological Chemistry.

P-glycoprotein Expression and Pharmacoresistant Epilepsy: Cause or Consequence?

M. Symms, R. Hinz, J. Matthews, 2014 .

Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis.

R. Murray, P. McGuire, P. Grasby, 2007, The British journal of psychiatry. Supplement.

Calretinin-immunoreactive neurons in the human thalamus

A. Parent, M. Asselin, M. Fortin, 1998, Neuroscience.

Calretinin immunoreactivity in the thalamus of the squirrel monkey

A. Parent, M. Asselin, M. Fortin, 1996, Journal of Chemical Neuroanatomy.

Positron Emission Tomography Partial Volume Correction: Estimation and Algorithms

Alan C. Evans, Alexander Hammers, Roger N Gunn, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

A positron emission tomography (PET) investigation of the role of striatal dopamine (D2) receptor availability in spatial cognition

Paul M. Grasby, Mitul A. Mehta, Suzanne Reeves, 2005, NeuroImage.

Separation of Intra- And Extra-Vascular Spaces in Human Brain with DCE-MRI and 11C- Verapamil PET

A. Jackson, Xiaoping Zhu, M. Asselin, 2011 .

In vivo P-glycoprotein function before and after epilepsy surgery

S. Sisodiya, M. Koepp, E. Pataraia, 2014, Neurology.

Patterns of Distribution of [18F]6-Fluoro-L-m-Tyrosine in PET Images of Patients with Movements Disorders

C. Nahmias, M. Thompson, M. Asselin, 2002 .

Optimization of methods for quantification of rCBF using high-resolution [15O]H2O PET images

J C Matthews, M D Walker, M Feldmann, 2012, Physics in medicine and biology.

Regions of interest in the venous sinuses as input functions for quantitative PET.

C Nahmias, C. Nahmias, M. Asselin, 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [11C]diprenorphine test–retest data

Alexander Hammers, Gary Hotton, Rainer Hinz, 2007, NeuroImage.

Phase I evaluation of OXi4503, a vascular disrupting agent, in patients with advanced solid tumours

P. Price, A. Padhani, G. Rustin, 2007 .

Development and validation of a variance model for dynamic PET: uses in fitting kinetic data and optimizing the injected activity

T Jones, J C Matthews, C C Watson, 2010, Physics in medicine and biology.

Patient-specific noise-equivalent-counts from repeated, dose varying [O-15]H2O PET scans

P. Price, T. Jones, J. Matthews, 2007, 2007 IEEE Nuclear Science Symposium Conference Record.

The Validation Path of Hypoxia PET Imaging: Focus on Brain Tumours.

M. Asselin, N. Quartuccio, 2017, Current Medicinal Chemistry.

OC-0632: Oxygen enhanced-MRI is feasible, repeatable and detects radiotherapy-induced NSCLC hypoxia changes

Adam K. Featherstone, G. Parker, C. Faivre-Finn, 2018 .

Phase I evaluation of vascular disrupting agent OXi4503

P. Price, G. Rustin, M. Stratford, 2008 .

Quantification of PET Studies with the Very High-Affinity Dopamine D2/D3 Receptor Ligand [11C]FLB 457: Re-Evaluation of the Validity of using a Cerebellar Reference Region

Marie-Claude Asselin, Andrew J Montgomery, P. Grasby, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Equilibration of 6-[18F]fluoro-L-m-tyrosine between plasma and erythrocytes.

L. Wahl, C. Nahmias, M. Asselin, 2000, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Striatal changes in preproenkephalin mRNA levels in parkinsonian monkeys

A. Parent, M. Asselin, A Parent, 1994, Neuroreport.

The Proprotein Convertase SKI-1/S1P

N. Seidah, A. Pasquato, M. Dettin, 2006, Journal of Biological Chemistry.

Multi-resolution Bayesian regression in PET dynamic studies using wavelets

Rainer Hinz, Federico E. Turkheimer, John A. D. Aston, 2006, NeuroImage.

Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives.

M. Asselin, Gordon C Jayson, James P B O'Connor, 2008, The Lancet. Oncology.

Chapter 2 Comparison of HRRT and HR + Scanners

F. V. Velden, R. Boellaard, A. Lammertsma, 2017 .

The pre-synaptic dopaminergic system before and after the onset of psychosis: initial results

P. Grasby, O. Howes, M. Asselin, 2006, European Neuropsychopharmacology.

Dopaminergic regulation of peptide gene expression in the striatum of normal and parkinsonian monkeys.

A. Parent, M. Asselin, P. Côté, 1996, Advances in neurology.

Parametrically defined cerebral blood vessels as non-invasive blood input functions for brain PET studies.

Roger N Gunn, Vincent J Cunningham, Marie-Claude Asselin, 2004, Physics in medicine and biology.