D. Nittner

发表

p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway

A. Jochemsen, J. Marine, P. Hulpiau, 2013, Cell Death and Differentiation.

An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours

M. Ringnér, F. Speleman, B. Menten, 2010, Oncogene.

Phenotype molding of stromal cells in the lung tumor microenvironment

P. Carmeliet, S. Aerts, D. Lambrechts, 2018, Nature Medicine.

Zeb2 drives invasive and microbiota-dependent colon carcinoma

B. Lambrecht, G. Berx, L. Boon, 2020, Nature Cancer.

Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo

J. Vandesompele, J. Marine, M. Dyer, 2010, Cell Death and Differentiation.

IGF 2 : The Achilles ’ heel of p 53-deficiency ?

J. Marine, D. Nittner, F. Clermont, 2013 .

IGF2: The Achilles' heel of p53-deficiency?

J. Marine, D. Nittner, F. Clermont, 2012, EMBO molecular medicine.

Anti-Cancer Activity of Acri ﬂ avine as Metabolic Inhibitor of OXPHOS in Pancreas Cancer Xenografts

E. Van Cutsem, C. Verslype, J. Pelt, 2020 .

Gemcitabine induces Epithelial-to-Mesenchymal Transition in patient-derived pancreatic ductal adenocarcinoma xenografts.

E. Van Cutsem, C. Verslype, L. Libbrecht, 2019, American journal of translational research.

CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

M. Van Ranst, U. Himmelreich, A. Coosemans, 2019, Biology Open.

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma

S. Ogawa, S. Demeyer, K. Jacobs, 2022, bioRxiv.

PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia

K. Jacobs, J. Cools, K. De Keersmaecker, 2021, Journal of Hematology & Oncology.

Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop.

Susan M. Schlenner, D. Lambrechts, S. Jalkanen, 2022, Cancer cell.

PS917 SAFE TARGETING OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA BY SUBUNIT SELECTIVE GAMMA-SECRETASE INHIBITION

B. de Strooper, L. Serneels, S. Demeyer, 2019, HemaSphere.

Gold nanoparticle delivery to solid tumors: a multiparametric study on particle size and the tumor microenvironment

B. Manshian, S. Soenen, D. Nittner, 2022, Journal of nanobiotechnology.

Phenotype molding of stromal cells in the lung tumor microenvironment

P. Carmeliet, S. Aerts, D. Lambrechts, 2018, Nature Medicine.

Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis

P. Carmeliet, S. Morrison, G. Hannon, 2021, bioRxiv.

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

B. de Strooper, A. Liston, L. Serneels, 2019, Science Translational Medicine.

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

P. Agostinis, J. Marine, F. Rambow, 2018, Nature Communications.

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.

G. Berx, J. Marine, H. Gerhardt, 2017, Cell stem cell.

Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer

D. Lambrechts, E. Van Cutsem, R. Janky, 2020, Translational oncology.

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

P. Carmeliet, S. Morrison, G. Hannon, 2022, Nature.

Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop

Susan M. Schlenner, D. Lambrechts, J. Marine, 2021, bioRxiv.

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

P. Carmeliet, S. Morrison, G. Hannon, 2022, Nature.

Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation

F. Speleman, J. Vandesompele, A. Jochemsen, 2012, Nature Cell Biology.

TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.

J. Marine, E. Radaelli, F. Luciani, 2018, Cancer research.

The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype

G. Berx, J. Marine, D. Huylebroeck, 2020, Cancer Research.

Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer

D. Lambrechts, J. Cools, A. Uyttebroeck, 2023, British Journal of Cancer.

Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy

T. Roskams, P. Agostinis, J. Marine, 2023, Journal of Experimental & Clinical Cancer Research.

Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop.

Susan M. Schlenner, D. Lambrechts, S. Jalkanen, 2023, Cancer cell.

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

P. Agostinis, J. Marine, F. Rambow, 2018, Nature Communications.

Phenotype molding of stromal cells in the lung tumor microenvironment

P. Carmeliet, S. Aerts, D. Lambrechts, 2018, Nature Medicine.