B. Biller

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Effects of growth hormone deficiency on body composition and biomarkers of cardiovascular risk after definitive therapy for acromegaly

A. Klibanski, L. Hemphill, E. Lin, 2012, Clinical endocrinology.

Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase II trial.

S. Melmed, J. Schopohl, A. Colao, 2010, The Journal of clinical endocrinology and metabolism.

Long-term safety of pegvisomant in patients with acromegaly: comprehensive review of 1288 subjects in ACROSTUDY.

M. Buchfelder, E. Ghigo, M. Kołtowska-Häggström, 2012, The Journal of clinical endocrinology and metabolism.

Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas

Marco Boscaro, A. Colao, M. Boscaro, 2010, BMC endocrine disorders.

ReviewCushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas

Marco Boscaro, A. Colao, M. Boscaro, 2010 .

12-Month effects of once-weekly sustained-release growth hormone treatment in adults with GH deficiency

J. Roemmler, C. Strasburger, D. Cook, 2013, Pituitary.

Growth hormone replacement in adults: Real-world data from two large studies in US and Europe.

M. Molitch, J. Jørgensen, B. Biller, 2019, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO ADULT CARE.

S. Radovick, A. Hoffman, K. Yuen, 2019, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Clinical features of GH deficiency and effects of 3 years of GH replacement in adults with controlled Cushing's disease.

M. Kołtowska-Häggström, B. Biller, C. Höybye, 2010, European journal of endocrinology.

Efficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency.

A. Hoffman, B. Silverman, D. Cook, 2005, The Journal of clinical endocrinology and metabolism.

Sensitivity and specificity of six tests for the diagnosis of adult GH deficiency.

D. Cook, B. Biller, A. Zagar, 2002, The Journal of clinical endocrinology and metabolism.

Effects of testosterone therapy on cardiovascular risk markers in androgen-deficient women with hypopituitarism.

N. Rifai, A. Klibanski, B. Biller, 2007, The Journal of clinical endocrinology and metabolism.

The role of bilateral inferior petrosal sinus sampling in the diagnosis of Cushing's syndrome.

B. Biller, A. Utz, 2007, Arquivos brasileiros de endocrinologia e metabologia.

Clinically nonfunctioning pituitary tumors are monoclonal in origin.

A. Arnold, A. Klibanski, B. Biller, 1990, The Journal of clinical investigation.

Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation.

P. Dahlqvist, T. Olsson, H. Lennernäs, 2012, The Journal of clinical endocrinology and metabolism.

The current state of long-acting growth hormone preparations for growth hormone therapy

K. Yuen, B. Biller, B. Miller, 2018, Current opinion in endocrinology, diabetes, and obesity.

Growth Hormone Replacement Therapy in Adult Onset GH Deficiency : Effects on Body Composition in Men and Women in a Double-Blind , Randomized , Placebo-Controlled Trial

L. Phillips, A. Hoffman, M. Vance, 2005 .

Placebo-Controlled Trial Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency:

L. Phillips, A. Hoffman, A. Klibanski, 2004 .

Growth hormone (GH) replacement therapy in adult-onset gh deficiency: effects on body composition in men and women in a double-blind, randomized, placebo-controlled trial.

L. Phillips, A. Hoffman, M. Vance, 2004, The Journal of clinical endocrinology and metabolism.

Effects of Physiologic Growth Hormone Therapy on Bone Density and Body Composition in Patients with Adult-Onset Growth Hormone Deficiency

D. Schoenfeld, A. Klibanski, J. Finkelstein, 1996, Annals of Internal Medicine.

Discovery of Cushing’s Syndrome After Bariatric Surgery: Multicenter Series of 16 Patients

M. Fleseriu, N. Tritos, B. Biller, 2015, Obesity Surgery.

Abnormal cortisol secretion and responses to corticotropin-releasing hormone in women with hypothalamic amenorrhea.

A. Klibanski, H. Federoff, B. Biller, 1990 .

Late-night salivary cortisol may be valuable for assessing treatment response in patients with Cushing’s disease: 12-month, Phase III pasireotide study

M. Fleseriu, J. Newell-Price, B. Biller, 2016, Endocrine.

Consensus on diagnosis and management of Cushing's disease: a guideline update.

P. Chanson, A. Tabarin, H. Raff, 2021, The lancet. Diabetes & endocrinology.

A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update.

F. Casanueva, S. Melmed, F. Keleştimur, 2020, The Journal of clinical endocrinology and metabolism.

Osteopenia in men with a history of delayed puberty.

A. Klibanski, J. Finkelstein, B. Biller, 1992, The New England journal of medicine.

Progressive trabecular osteopenia in women with hyperprolactinemic amenorrhea.

A. Klibanski, B. Biller, D. Rosenthal, 1992, The Journal of clinical endocrinology and metabolism.

Long‐term efficacy and safety of once‐monthly pasireotide in Cushing's disease: A Phase III extension study

M. Fleseriu, M. Roughton, J. Newell-Price, 2019, Clinical endocrinology.

Once-weekly Somapacitan is Effective and Well Tolerated in Adults with GH Deficiency: A Randomized Phase 3 Trial

G. Johannsson, K. Takano, B. Biller, 2020, The Journal of clinical endocrinology and metabolism.

Levoketoconazole: a novel treatment for endogenous Cushing's syndrome

M. Fleseriu, R. Auchus, B. Biller, 2021, Expert review of endocrinology & metabolism.

Advances in the Medical Treatment of Cushing Disease.

N. Tritos, B. Biller, 2020, Endocrinology and metabolism clinics of North America.

Medical Management of Cushing Disease.

N. Tritos, B. Biller, 2019, Neurosurgery clinics of North America.

Medical Therapy for Cushing's Syndrome in the Twenty-first Century.

N. Tritos, B. Biller, 2018, Endocrinology and metabolism clinics of North America.

Medical Therapies in Cushing’s Syndrome

N. Tritos, B. Biller, 2017 .

Complications of Cushing's syndrome: state of the art.

A. Isidori, M. D. De Martino, J. Newell-Price, 2016, The lancet. Diabetes & endocrinology.

LCI699, a potent 11β-hydroxylase inhibitor, normalizes urinary cortisol in patients with Cushing's disease: results from a multicenter, proof-of-concept study.

X. Bertagna, M. Fleseriu, M. Boscaro, 2014, The Journal of clinical endocrinology and metabolism.

A new therapeutic approach in the medical treatment of Cushing's syndrome: glucocorticoid receptor blockade with mifepristone.

M. Fleseriu, M. Molitch, B. Biller, 2013, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Medical management of Cushing’s disease

N. Tritos, B. Biller, 2014, Journal of Neuro-Oncology.

Follow-up intervals in patients with Cushing’s disease: recommendations from a panel of experienced pituitary clinicians

M. Broder, M. Neary, D. Cherepanov, 2017, Pituitary.

Growth Hormone: Health Considerations Beyond Height Gain

P. Czernichow, A. Colao, W. Kiess, 2010, Pediatrics.

Hypertension in Acromegaly in Relationship to Biochemical Control and Mortality: Global ACROSTUDY Outcomes

A. Luger, A. J. van der Lely, B. Biller, 2020, Frontiers in Endocrinology.

The biochemical diagnosis of adrenal insufficiency with modern cortisol assays: Reappraisal in the setting of opioid exposure and hospitalization

L. Nachtigall, B. Biller, K. Miller, 2021, Clinical endocrinology.

Age and bone mass in premenopausal women.

C. Hayes, A. Klibanski, B. Biller, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Unreplaced sex steroid deficiency, corticotropin deficiency, and lower IGF-I are associated with lower bone mineral density in adults with growth hormone deficiency: a KIMS database analysis.

S. Greenspan, D. Cook, N. Tritos, 2011, The Journal of clinical endocrinology and metabolism.

Surgical debulking of pituitary adenomas improves responsiveness to octreotide lar in the treatment of acromegaly

P. Cappabianca, A. Mamelak, R. Fahlbusch, 2017, Pituitary.

Efficacy and safety of once-monthly pasireotide in Cushing's disease: a 12 month clinical trial.

M. Boscaro, M. Yamada, M. Roughton, 2018, The lancet. Diabetes & endocrinology.

American Association of Clinical Endocrinologists medical guidelines for clinical practice for growth hormone use in growth hormone-deficient adults and transition patients - 2009 update.

M. Vance, K. Yuen, D. Cook, 2009, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Adipokines and Cardiovascular Risk in Cushing’s Syndrome

A. Klibanski, B. Biller, M. Misra, 2011, Neuroendocrinology.

Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective

L. Cohen, S. Radovick, A. Hoffman, 2019, Hormone Research in Paediatrics.

Macimorelin as a Diagnostic Test for Adult GH Deficiency

P. Chanson, A. Zakrzewska, M. Korbonits, 2018, The Journal of clinical endocrinology and metabolism.

Treatment of ACTH-dependent Cushing ’ s syndrome : a consensus statement

J. Bertherat, X. Bertagna, M. Vance, 2008 .

Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.

L. Nieman, J. Bertherat, X. Bertagna, 2008, The Journal of clinical endocrinology and metabolism.

Diagnostic errors after inferior petrosal sinus sampling.

A. Klibanski, S. Grinspoon, D. Dorer, 2004, The Journal of clinical endocrinology and metabolism.

Macimorelin (AEZS-130)-Stimulated Growth Hormone (GH) Test: Validation of a Novel Oral Stimulation Test for the Diagnosis of Adult GH Deficiency

A. Dobs, M. Molitch, R. Swerdloff, 2013, The Journal of clinical endocrinology and metabolism.

Sensitivity and specificity of the macimorelin test for diagnosis of AGHD.

P. Chanson, M. Korbonits, C. Strasburger, 2020, Endocrine connections.

High variability in baseline urinary free cortisol values in patients with Cushing’s disease

A. Colao, J. Newell-Price, B. Biller, 2013, Clinical endocrinology.

Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial.

N. Rifai, A. Klibanski, D. Hayden, 2000, Annals of internal medicine.

Assessment of growth hormone (GH) secretion in men with adult-onset GH deficiency compared with that in normal men--a clinical research center study.

D. Schoenfeld, A. Klibanski, D. Clemmons, 1996, The Journal of clinical endocrinology and metabolism.

Pituitary apoplexy: large surgical series with grading system.

B. Swearingen, B. Biller, D. Jho, 2014, World neurosurgery.

Multidisciplinary management of acromegaly: A consensus

P. Chanson, A. Mamelak, F. Casanueva, 2020, Reviews in Endocrine and Metabolic Disorders.

The Network for the Enhancement of Endocrinology and Oncology Knowledge: a case-based consideration of current practice in Cushing's disease and acromegaly.

B. Biller, M. Sheppard, 2009, Best practice & research. Clinical endocrinology & metabolism.

Response to GH treatment in adult GH deficiency is predicted by gender, age, and IGF1 SDS but not by stimulated GH-peak.

G. Brabant, M. Buchfelder, B. Biller, 2013, European journal of endocrinology.

Clinical characteristics, timing of peak responses and safety aspects of two dosing regimens of the glucagon stimulation test in evaluating growth hormone and cortisol secretion in adults

K. Yuen, D. Cook, B. Biller, 2013, Pituitary.

Clinical review: Is lack of recombinant growth hormone (GH)-releasing hormone in the United States a setback or time to consider glucagon testing for adult GH deficiency?

M. Molitch, K. Yuen, D. Cook, 2009, The Journal of clinical endocrinology and metabolism.

Osteopenia in Women With Hypothalamic Amenorrhea: A Prospective Study

D. Schoenfeld, A. Klibanski, B. Biller, 1991, Obstetrics and gynecology.

Epidemiology and Etiology of Cushing’s Disease

N. Tritos, B. Biller, 2017 .

Growth Hormone Research Society perspective on biomarkers of GH action in children and adults

P. Chanson, S. Radovick, M. Dattani, 2018, Endocrine connections.

Accuracy of laboratory tests for the diagnosis of Cushing's syndrome.

A. Klibanski, N. Tritos, B. Biller, 2020, The Journal of clinical endocrinology and metabolism.

Body composition and endocrine function in women with acquired immunodeficiency syndrome wasting.

A. Klibanski, S. Grinspoon, B. Biller, 1997, The Journal of clinical endocrinology and metabolism.

Outcomes of proton therapy for patients with functional pituitary adenomas.

A. Niemierko, H. Shih, M. Bussière, 2014, International journal of radiation oncology, biology, physics.

Proton stereotactic radiotherapy for persistent adrenocorticotropin-producing adenomas.

J. Petit, M. Bussière, J. Loeffler, 2008, The Journal of clinical endocrinology and metabolism.

Proton stereotactic radiosurgery in management of persistent acromegaly.

J. Petit, M. Bussière, J. Loeffler, 2007, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Growth hormone and bone

N. Tritos, B. Biller, 2009, Current opinion in endocrinology, diabetes, and obesity.

Effect of Growth Hormone Replacement on BMD in Adult‐Onset Growth Hormone Deficiency

J. Scism-Bacon, P. Snyder, A. Mooradian, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Withdrawal of long-term physiological growth hormone (GH) administration: differential effects on bone density and body composition in men with adult-onset GH deficiency.

D. Schoenfeld, A. Klibanski, D. Hayden, 2000, The Journal of clinical endocrinology and metabolism.

Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency.

G. Johannsson, B. Biller, C. Gunnarsson, 2016, The Journal of clinical endocrinology and metabolism.

Clinical and biochemical evaluation of Cushing's syndrome.

B. Biller, C. Meier, 1997, Endocrinology and metabolism clinics of North America.

The role of the clinical laboratory in the diagnosis of Cushing syndrome.

A. Klibanski, B. Biller, Christine A Garcia, 2003, American journal of clinical pathology.

Pathogenesis of pituitary Cushing's syndrome. Pituitary versus hypothalamic.

B. Biller, 1994, Endocrinology and metabolism clinics of North America.

Early recognition of growth abnormalities permitting early intervention

P. Czernichow, M. Haymond, W. Kiess, 2013, Acta paediatrica.

Concomitant medication use can confound interpretation of the combined dexamethasone-corticotropin releasing hormone test in Cushing's syndrome.

Hang Lee, A. Klibanski, L. Nachtigall, 2009, The Journal of clinical endocrinology and metabolism.

WITHDRAWN: The diagnosis of Cushing's syndrome: an endocrine society clinical practice guideline.

V. Montori, L. Nieman, M. Savage, 2009, European journal of endocrinology.

Comorbidity and cardiovascular risk factors in adult GH deficiency following treatment for Cushing's disease or non-functioning pituitary adenomas during childhood.

M. Kołtowska-Häggström, G. Johannsson, B. Biller, 2012, European journal of endocrinology.

A 12-month phase 3 study of pasireotide in Cushing's disease.

A. Colao, J. Newell-Price, B. Biller, 2012, The New England journal of medicine.

Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease.

E. Hedley‐Whyte, A. Arnold, A. Klibanski, 1992, The Journal of clinical endocrinology and metabolism.

G. Brabant, M. Buchfelder, B. Biller, 2012, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Comparison of pegvisomant and long-acting octreotide in patients with acromegaly naïve to radiation and medical therapy

R. K. Hutson, E. Ghigo, A. Klibanski, 2009 .

Is GH dosing optimal in female patients with adult‐onset GH deficiency? An analysis from the NordiNet® International Outcome Study

B. Biller, Matthias M. Weber, C. Höybye, 2017, Clinical endocrinology.

Stereotactic proton radiosurgery in the management of persistent acromegaly

T. Yock, A. Thornton, B. Swearingen, 2001 .

Pegvisomant : a growth hormone receptor antagonist used in the treatment of acromegaly

N. Tritos, B. Biller, 2016 .

Abnormal cortisol secretion and responses to corticotropin-releasing hormone in women with hypothalamic amenorrhea.

A. Klibanski, H. Federoff, B. Biller, 1990, The Journal of clinical endocrinology and metabolism.

Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations

P. Chanson, L. Cohen, F. Casanueva, 2016, European journal of endocrinology.

Androgens and bone density in women with hypopituitarism.

A. Klibanski, B. Biller, K. Miller, 2002, The Journal of clinical endocrinology and metabolism.

The potential role of the investigational somatostatin analog pasireotide (SOM230) in the treatment of neuroendocrine disorders

L. Nachtigall, B. Biller, 2006 .

Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa.

A. Klibanski, B. Biller, D. Rosenthal, 1989, The Journal of clinical endocrinology and metabolism.

ALL-CAUSE MORTALITY IN PATIENTS WITH ACROMEGALY TREATED WITH PEGVISOMANT AN ACROSTUDY ANALYSIS.

A. Klibanski, N. Tritos, B. Biller, 2020, European journal of endocrinology.

The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient adults.

L. Phillips, A. Hoffman, M. Vance, 2002, The Journal of clinical endocrinology and metabolism.

Significance of proliferating cell nuclear antigen index in predicting pituitary adenoma recurrence.

E. Hedley‐Whyte, A. Klibanski, S. M. de la Monte, 1993, Journal of neurosurgery.

Clinical review 62: Laboratory assessment of adrenal insufficiency.

S. Grinspoon, B. Biller, 1994, The Journal of clinical endocrinology and metabolism.

Clinical and reimbursement issues in growth hormone use in adults.

M. Vance, D. Cook, B. Biller, 2000, The American journal of managed care.

Concepts in the Diagnosis of Adult Growth Hormone Deficiency

B. Biller, 2007, Hormone Research in Paediatrics.

Pregnancy outcomes in women with growth hormone deficiency.

A. Luger, B. Biller, M. Riedl, 2015, Fertility and sterility.

Clinical features of nonpituitary sellar lesions in a large surgical series

A. Klibanski, B. Swearingen, B. Biller, 2010, Clinical endocrinology.

Treatment of pituitary-dependent Cushing's disease with the multireceptor ligand somatostatin analog pasireotide (SOM230): a multicenter, phase II trial.

Y. Wang, A. Tabarin, J. Bertherat, 2009, The Journal of clinical endocrinology and metabolism.

Extended treatment of Cushing’s disease with pasireotide: results from a 2-year, Phase II study

J. Bertherat, M. Fleseriu, J. Schopohl, 2013, Pituitary.

Cyclic Cushing’s Disease

N. Tritos, B. Biller, 2011 .

Transsphenoidal surgery for cushing disease after nondiagnostic inferior petrosal sinus sampling.

S. Sheth, A. Klibanski, M. Mian, 2012, Neurosurgery.

Pituitary surgery and postoperative management in Cushing's disease.

B. Swearingen, B. Biller, A. Utz, 2005, Endocrinology and metabolism clinics of North America.

Clinical implications of residual growth hormone (GH) response to provocative testing in adults with severe GH deficiency.

G. Brabant, M. Buchfelder, B. Biller, 2007, The Journal of clinical endocrinology and metabolism.

Clinical implications of residual GH response to provocative testing in adults with severe growth hormone deficiency

G. Brabant, M. Buchfelder, M. Kołtowska-Häggström, 2007 .

Current concepts of the diagnosis of adult growth hormone deficiency

N. Tritos, B. Biller, 2020, Reviews in Endocrine and Metabolic Disorders.

Effects of Growth Hormone Administration on Inflammatory and Other Cardiovascular Risk Markers in Men with Growth Hormone Deficiency

N. Rifai, A. Klibanski, D. Hayden, 2000, Annals of Internal Medicine.

Weekly somapacitan had no adverse effects on glucose metabolism in adults with growth hormone deficiency

K. Ho, G. Johannsson, K. Yuen, 2022, Pituitary.

Long-term treatment of Cushing’s disease with pasireotide: 5-year results from an open-label extension study of a Phase III trial

G. Arnaldi, J. Schopohl, C. Scaroni, 2017, Endocrine.

Osilodrostat, a potent oral 11β-hydroxylase inhibitor: 22-week, prospective, Phase II study in Cushing’s disease

Jacques Young, X. Bertagna, Tomoaki Tanaka, 2015, Pituitary.

Management of the Clinically Inapparent Adrenal Mass (Incidentaloma)

G. Braunstein, E. Harris, M. Posner, 2003, Annals of Internal Medicine.

MOD-4023, a long-acting carboxy-terminal peptide-modified human growth hormone: results of a Phase 2 study in growth hormone-deficient adults

M. Bidlingmaier, C. Strasburger, L. Bajnok, 2016, European journal of endocrinology.

Effects of long-term growth hormone replacement in adults with growth hormone deficiency following cure of acromegaly: a KIMS analysis.

M. Korbonits, A. Klibanski, G. Johannsson, 2014, The Journal of clinical endocrinology and metabolism.

A Pituitary Society update to acromegaly management guidelines

S. Samson, S. Melmed, M. Fleseriu, 2020, Pituitary.

Cushing's disease.

N. Tritos, B. Biller, 2014, Handbook of clinical neurology.

Levoketoconazole improves clinical signs and symptoms and patient-reported outcomes in patients with Cushing’s syndrome

M. Fleseriu, F. Pecori Giraldi, B. Biller, 2020, Pituitary.

Health Care Burden in Patients With Adrenal Insufficiency

G. Johannsson, B. Biller, C. Gunnarsson, 2017, Journal of the Endocrine Society.

Gonadotropin and alpha-subunit responses to chronic gonadotropin-releasing hormone analog administration in patients with glycoprotein hormone-secreting pituitary tumors.

W. Crowley, A. Klibanski, J. Jameson, 1989, The Journal of clinical endocrinology and metabolism.

Occult Leydig cell tumor in a patient with gynecomastia.

E. Brogi, B. Biller, M. Anderson, 2001, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Body fat distribution measured with CT: correlations in healthy subjects, patients with anorexia nervosa, and patients with Cushing syndrome.

C W Hayes, C. Hayes, A. Klibanski, 1989, Radiology.

The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline.

V. Montori, L. Nieman, M. Savage, 2008, The Journal of clinical endocrinology and metabolism.

Treatment of prolactin-secreting macroadenomas with the once-weekly dopamine agonist cabergoline.

M. Vance, A. Klibanski, M. Molitch, 1996, The Journal of clinical endocrinology and metabolism.

Dopamine Agonists Can Reduce Cystic Prolactinomas.

A. Klibanski, B. Swearingen, B. Biller, 2016, The Journal of clinical endocrinology and metabolism.

Treatment of prolactin-secreting pituitary macroadenomas with the long-acting non-ergot dopamine agonist CV 205-502.

M. Vance, A. Klibanski, M. Molitch, 1990, Annals of internal medicine.

Guidelines for the diagnosis and treatment of hyperprolactinemia.

M. Molitch, R. Rebar, B. Biller, 1999, The Journal of reproductive medicine.

Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly.

P. Black, A. Klibanski, S. Grinspoon, 1998, The Journal of clinical endocrinology and metabolism.

Clinical Review#: Potential cardiac valve effects of dopamine agonists in hyperprolactinemia.

A. Klibanski, B. Biller, E. Valassi, 2010, The Journal of clinical endocrinology and metabolism.

Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.

A. Tabarin, M. Murad, L. Nieman, 2015, The Journal of clinical endocrinology and metabolism.

Effectiveness of first-line pegvisomant monotherapy in acromegaly: an ACROSTUDY analysis.

P. Chanson, A. Klibanski, N. Tritos, 2017, European journal of endocrinology.

Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): A Pituitary Society Statement

P. Chanson, A. Mamelak, R. Fahlbusch, 2017, Pituitary.

The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa.

D. Schoenfeld, A. Klibanski, B. Biller, 1995, The Journal of clinical endocrinology and metabolism.

Management of Cushing disease

N. Tritos, B. Swearingen, B. Biller, 2011, Nature Reviews Endocrinology.

Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome

John J. Kopchick, Véronique Beauloye, Jens Sandahl Christiansen, 2013, The Journal of clinical endocrinology and metabolism.

Treatment of Cushing’s syndrome with osilodrostat: practical applications of recent studies with case examples

M. Fleseriu, B. Biller, 2022, Pituitary.

Status of long-acting-growth hormone preparations--2015.

A. Hoffman, P. Cohen, J. Christiansen, 2015, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Comparison of pegvisomant and long-acting octreotide in patients with acromegaly naïve to radiation and medical therapy.

R. K. Hutson, E. Ghigo, A. Klibanski, 2009, Journal of endocrinological investigation.

OR16-2 Osilodrostat Treatment in Cushing's Disease (CD): Results from a Phase III, Multicenter, Double-Blind, Randomized Withdrawal Study (LINC 3)

X. Bertagna, M. Fleseriu, R. Leelawattana, 2019, Journal of the Endocrine Society.

Radiation Therapy in Patients With Cushing Disease

J. Loeffler, N. Tritos, B. Biller, 2019, Encyclopedia of Endocrine Diseases.

Current management of Cushing's disease

N. Tritos, B. Biller, 2019, Journal of internal medicine.

Accuracy of Late-Night Salivary Cortisol in Evaluating Postoperative Remission and Recurrence in Cushing's Disease.

A. Klibanski, L. Nachtigall, N. Tritos, 2015, The Journal of clinical endocrinology and metabolism.

Delayed remission after transsphenoidal surgery in patients with Cushing's disease.

A. Klibanski, M. Losa, F. Pecori Giraldi, 2010, The Journal of clinical endocrinology and metabolism.

Management of recurrent and refractory Cushing's disease with reoperation and/or proton beam radiosurgery.

J. Petit, J. Loeffler, A. Klibanski, 2007, Clinical neurosurgery.

COVID-19 and Cushing's syndrome: recommendations for a special population with endogenous glucocorticoid excess

R. Ferrigno, A. Isidori, A. Grossman, 2020, The Lancet Diabetes & Endocrinology.

Long-term efficacy and safety of osilodrostat in Cushing’s disease: final results from a Phase II study with an optional extension phase (LINC 2)

G. Arnaldi, Jacques Young, J. Bertherat, 2022, Pituitary.

Long-term outcomes of osilodrostat in Cushing’s disease: LINC 3 study extension

M. Fleseriu, C. Scaroni, M. Roughton, 2022, European journal of endocrinology.

Osilodrostat for the treatment of Cushing's disease: efficacy, stability, and persistence - Authors' reply.

S. Melmed, M. Fleseriu, M. Gadelha, 2022, The lancet. Diabetes & endocrinology.

Use of late-night salivary cortisol to monitor response to medical treatment in Cushing’s disease

A. Tabarin, M. Fleseriu, M. Gadelha, 2019, European journal of endocrinology.

Efficacy and safety of levoketoconazole in the treatment of endogenous Cushing's syndrome (SONICS): a phase 3, multicentre, open-label, single-arm trial.

M. Fleseriu, R. Auchus, B. Biller, 2019, The lancet. Diabetes & endocrinology.

Health care resource use and costs among patients with cushing disease.

B. Swearingen, B. Biller, Shih-Yin Chen, 2011, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Long-term mortality after transsphenoidal surgery for Cushing disease.

A. Klibanski, S. Grinspoon, B. Swearingen, 1999 .

Pasireotide treatment significantly improves clinical signs and symptoms in patients with Cushing's disease: results from a Phase III study

J. Schopohl, J. Newell-Price, A. Lacroix, 2014, Clinical endocrinology.

Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.

M. Fleseriu, M. Molitch, B. Biller, 2012, The Journal of clinical endocrinology and metabolism.

Investigation of impulsivity in patients on dopamine agonist therapy for hyperprolactinemia: a pilot study

L. Stoeckel, A. Klibanski, A. Evins, 2014, Pituitary.

Diagnosis and management of pituitary disorders

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Growth hormone decreases visceral fat and improves cardiovascular risk markers in women with hypopituitarism: a randomized, placebo-controlled study.

A. Klibanski, L. Nachtigall, B. Biller, 2008, The Journal of clinical endocrinology and metabolism.

A longer interval without GH replacement and female gender are associated with lower bone mineral density in adults with childhood-onset GH deficiency: a KIMS database analysis.

S. Greenspan, D. Cook, N. Tritos, 2012, European journal of endocrinology.

Revised GH and cortisol cut-points for the glucagon stimulation test in the evaluation of GH and hypothalamic–pituitary–adrenal axes in adults: results from a prospective randomized multicenter study

J. Bena, K. Yuen, B. Biller, 2016, Pituitary.

Overweight/Obese adults with pituitary disorders require lower peak growth hormone cutoff values on glucagon stimulation testing to avoid overdiagnosis of growth hormone deficiency.

P. Sluss, M. Bredella, K. Yuen, 2014, The Journal of clinical endocrinology and metabolism.

Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency?

Brenda J. Crowe, D. Clemmons, K. Ho, 2002, The Journal of clinical endocrinology and metabolism.

A Long-Acting Human Growth Hormone With Delayed Clearance (VRS-317): Results of a Double-Blind, Placebo-Controlled, Single Ascending Dose Study in Growth Hormone–Deficient Adults

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Effects of once-weekly sustained-release growth hormone: a double-blind, placebo-controlled study in adult growth hormone deficiency.

J. Roemmler, C. Strasburger, D. Cook, 2011, The Journal of clinical endocrinology and metabolism.

Effect of growth hormone replacement therapy on the quality of life in women with growth hormone deficiency who have a history of acromegaly versus other disorders.

A. Klibanski, B. Biller, E. Valassi, 2012, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Growth hormone deficiency after treatment of acromegaly: a randomized, placebo-controlled study of growth hormone replacement.

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Growth hormone deficiency is associated with decreased quality of life in patients with prior acromegaly.

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Pathologic and clinical features of pituitary adenomas showing TSH immunoreactivity

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American Association of Clinical Endocrinologists medical guidelines for clinical practice for growth hormone use in growth hormone-deficient adults and transition patients - 2009 update: executive summary of recommendations.

M. Vance, K. Yuen, D. Cook, 2009, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Effects of prolactin and estrogen deficiency in amenorrheic bone loss.

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Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a doubleblind, randomised withdrawal phase.

X. Bertagna, M. Fleseriu, R. Leelawattana, 2020, The lancet. Diabetes & endocrinology.

Pregnancy outcomes in women receiving growth hormone replacement therapy enrolled in the NordiNet® International Outcome Study (IOS) and the American Norditropin® Studies: Web-Enabled Research (ANSWER) Program

P. Carroll, B. Biller, C. Höybye, 2021, Pituitary.

Long-term treatment with pegvisomant: observations from 2090 acromegaly patients in ACROSTUDY.

M. Buchfelder, E. Ghigo, C. Strasburger, 2018, European journal of endocrinology.

Increasing frequency of combination medical therapy in the treatment of acromegaly with the GH receptor antagonist pegvisomant

C. Strasburger, B. Biller, A. Mattsson, 2018, European journal of endocrinology.

A decade of the Massachusetts General Hospital Neuroendocrine Clinical Center.

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Medical therapy for prolactinomas and somatotroph adenomas.

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Diagnostic evaluation of hyperprolactinemia.

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Long-Term Mortality after Transsphenoidal Surgery for Cushing Disease

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Update on radiation therapy in patients with Cushing’s disease

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Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation

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Diagnostic Dilemmas in the Management of Hypothalamic‐Pituitary‐Adrenal Disorders

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The effect of growth hormone (GH) replacement on blood glucose homeostasis in adult nondiabetic patients with GH deficiency: real‐life data from the NordiNet® International Outcome Study

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Gender effects on cardiac valvular function in hyperprolactinaemic patients receiving cabergoline: a retrospective study

A. Klibanski, S. Grinspoon, L. Nachtigall, 2010, Clinical endocrinology.

Predictors of the effects of 4 years of growth hormone replacement on bone mineral density in patients with adult‐onset growth hormone deficiency – a KIMS database analysis

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Radiotherapy, Especially at Young Age, Increases the Risk for De Novo Brain Tumors in Patients Treated for Pituitary/Sellar Lesions

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Characterization of cyclic Cushing's disease using late night salivary cortisol testing

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BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.

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Bone microarchitecture and estimated bone strength in men with active acromegaly.

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Effects of testosterone replacement in androgen-deficient women with hypopituitarism: a randomized, double-blind, placebo-controlled study.

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Truncal adiposity, relative growth hormone deficiency, and cardiovascular risk.

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Age and bone mass in premenopausal women

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Advances in medical therapies for Cushing's syndrome.

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Results from the phase 3 multicenter SONICS study of levoketoconazole: subgroup analysis of Cushing's syndrome patients with diabetes mellitus

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Levoketoconazole treatment in endogenous Cushing’s syndrome: extended evaluation of clinical, biochemical, and radiologic outcomes

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Pasireotide (SOM230) demonstrates efficacy in patients with Cushing's disease: results from a large, randomized-dose, double-blind, Phase III study

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Long-term (19-month) control of urinary free cortisol with osilodrostat in patients with Cushing's disease: results from an extension to the LINC-2 study

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Pasireotide alone or in combination with cabergoline effectively controls urinary free cortisol levels: results from a prospective study in patients with Cushing's disease (CAPACITY)

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Late-night salivary cortisol (LNSC) levels in a Phase III study of long-acting pasireotide in patients with Cushing's disease (CD)

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Patients with Cushing's disease achieve normal urinary cortisol with LCI699, a potent 11[beta]-hydroxylase inhibitor: preliminary results from a multicenter, proof-of-concept study

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Effects of physiological growth hormone (GH) therapy on cognition and quality of life in patients with adult-onset GH deficiency.

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Predictors of response to long-acting pasireotide in patients with Cushing's disease during a Phase III study

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Long-term efficacy and safety of once-monthly pasireotide in patients with Cushing's disease: A Phase III extension study

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Improvement in clinical signs and symptoms of Cushing's disease following 12 months' pasireotide therapy

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Contextualized analysis of a needs assessment using the Theoretical Domains Framework: a case example in endocrinology

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Effects of growth hormone (GH) administration on homocyst(e)ine levels in men with GH deficiency: a randomized controlled trial.

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Dose–exposure–IGF-I response of once-weekly somapacitan in adults with GH deficiency

G. Johannsson, C. Hollensen, B. Biller, 2022, European journal of endocrinology.

Hyperprolactinemia.

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GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults

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Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas

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The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient adults.

L. Phillips, M. Vance, A. Illeperuma, 2002, The Journal of clinical endocrinology and metabolism.

Long-term Effectiveness and Safety of GH Replacement Therapy in Adults ≥60 Years: Data From NordiNet® IOS and ANSWER

B. Biller, C. Höybye, Jean-Marc Ferran, 2023, Journal of the Endocrine Society.

Reduced CV risk with long-term GH replacement in AGHD: data from two large observational studies

B. Biller, C. Höybye, Jean-Marc Ferran, 2022, Endocrine connections.

Abstract #999926: Effect of Dosing and Titration of Osilodrostat on Efficacy and Safety in Patients With Cushing's Disease (CD): Results From Two Phase III Trials (LINC3 and LINC4)

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Effects of once-weekly sustained-release growth hormone: a double-blind, placebo-controlled study in adult growth hormone deficiency.

J. Roemmler, C. Strasburger, D. Cook, 2011, The Journal of clinical endocrinology and metabolism.

Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement

P. Chanson, S. Melmed, M. Fleseriu, 2023, Nature Reviews Endocrinology.

Gender effects on cardiac valvular function in hyperprolactinaemic patients receiving cabergoline: a retrospective study

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Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome

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Surgical debulking of pituitary adenomas improves responsiveness to octreotide lar in the treatment of acromegaly

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Pasireotide treatment significantly improves clinical signs and symptoms in patients with Cushing's disease: results from a Phase III study

J. Schopohl, J. Newell-Price, A. Lacroix, 2014, Clinical endocrinology.

American Association of Clinical Endocrinologists medical guidelines for clinical practice for growth hormone use in growth hormone-deficient adults and transition patients - 2009 update.

M. Vance, K. Yuen, D. Cook, 2009, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Long-term safety of pegvisomant in patients with acromegaly: comprehensive review of 1288 subjects in ACROSTUDY.

M. Buchfelder, E. Ghigo, C. Strasburger, 2012, The Journal of clinical endocrinology and metabolism.