Yixin Zhang

发表

Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library.

Michael A. Stravs, G. Schneider, Tim Geppert, 2012, Chemistry.

High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

Christoph E. Dumelin, E. Rizzi, G. De Bellis, 2008, Proceedings of the National Academy of Sciences.

Isolation of a Small‐Molecule Inhibitor of the Antiapoptotic Protein Bcl‐xL from a DNA‐Encoded Chemical Library

Christoph E. Dumelin, M. Grütter, A. Villa, 2010, ChemMedChem.

2-Methoxydiol derivatives as new tubulin and HDAC dual-targeting inhibitors, displaying antitumor and antiangiogenic response.

Yixin Zhang, Y. Duan, Mo-ran Sun, 2022, Bioorganic chemistry.

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions.

Dario Neri, Christoph E Dumelin, Christoph E. Dumelin, 2008, Bioorganic & medicinal chemistry letters.

Discovery of TNF inhibitors from a DNA-encoded chemical library based on diels-alder cycloaddition.

Peter Bühlmann, Dario Neri, Jörg Scheuermann, 2009, Chemistry & biology.

Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors

Yixin Zhang, Y. Duan, Mo-ran Sun, 2022, Journal of enzyme inhibition and medicinal chemistry.

Angiogenesis, Anti-Tumor, and Anti-Metastatic Activity of Novel α-Substituted Hetero-Aromatic Chalcone Hybrids as Inhibitors of Microtubule Polymerization

Yixin Zhang, Y. Duan, Mo-ran Sun, 2021, Frontiers in Chemistry.

Automated screening for small organic ligands using DNA-encoded chemical libraries

Michael A. Stravs, J. Scheuermann, D. Neri, 2016, Nature Protocols.

Augmented photoswitching modulates immune signaling.

G. Fischer, Yixin Zhang, F. Erdmann, 2009, Nature chemical biology.

Unexpected Side Chain Effects at Residue 8 of Cyclosporin A Derivatives Allow Photoswitching of Immunosuppression*

R. Baumgrass, M. Schutkowski, G. Fischer, 2005, Journal of Biological Chemistry.

Branches on the α‐C Atom of Cyclosporin A Residue 3 Result in Direct Calcineurin Inhibition and Rapid Cyclophilin 18 Binding

M. Schutkowski, G. Fischer, Yixin Zhang, 2004, Chembiochem : a European journal of chemical biology.

Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14.

Wei Zhang, Yixin Zhang, Rui Wang, 2016, European journal of cell biology.

Discovery of a novel piperlongumine analogue as a microtubule polymerization inhibitor with potent anti-angiogenic and anti-metastatic efficacy.

H. Yang, Yixin Zhang, Y. Duan, 2022, European journal of medicinal chemistry.

Specificity from non-specific interaction: regulation of TNF-  activity by DNA

Yixin Zhang, Weilin Lin, Helena Andrade, 2019 .

MEL-N16: A Series of Novel Endomorphin Analogs with Good Analgesic Activity and a Favorable Side Effect Profile.

Dan-dan Wang, Yixin Zhang, Dongxu Yang, 2017, ACS chemical neuroscience.

Bioactive Pimarane‐Type Diterpenes from Marine Organisms

Xiao-ling Lu, Yixin Zhang, Xiao-yu Liu, 2018, Chemistry & biodiversity.

Design, synthesis, and pharmacological characterization of novel endomorphin-1 analogues as extremely potent μ-opioid agonists.

H. Ji, Dan-dan Wang, Y. Wang, 2013, Journal of medicinal chemistry.

Substitution in Position 3 of Cyclosporin A Abolishes the Cyclophilin-mediated Gain-of-function Mechanism but Not Immunosuppression*

Andreas Radbruch, A. Thiel, R. Baumgrass, 2004, Journal of Biological Chemistry.

DRME: Count-based differential RNA methylation analysis at small sample size scenario.

Yufei Huang, Jia Meng, Runsheng Chen, 2016, Analytical biochemistry.

A portable albumin binder from a DNA-encoded chemical library.

Christof Baltes, Samu Melkko, Susanne C. Beck, 2008, Angewandte Chemie.

Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors

Rui Wang, Yixin Zhang, Q. Zeng, 2016, Peptides.

Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.

Yixin Zhang, Y. Duan, Jinling Qin, 2021, European journal of medicinal chemistry.

Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin.

A. Fujimura, G. Schwartz, Q. Al-Awqati, 2005, American journal of physiology. Renal physiology.

Characterization of DNA-conjugated compounds using a regenerable chip.

V. Uzunova, F. Reddavide, Yixin Zhang, 2015, Analytical chemistry.

Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration.

Dan-dan Wang, Yixin Zhang, Y. Wang, 2015, Bioorganic & Medicinal Chemistry Letters.

Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.

Beiyan Zou, Hongkang Zhang, Min Li, 2014, European journal of pharmacology.

Substrate-based design of reversible Pin1 inhibitors.

U. Reimer, S. Füssel, M. Schutkowski, 2002, Biochemistry.

A method of identifying high-affinity complexes of two ligands and a receptor device for performing the method and self-assembling-chemical library for use in the method

F. Reddavide, Yixin Zhang, Weilin Lin, 2014 .

DNA-encoded chemical libraries for the discovery of MMP-3 inhibitors.

Samu Melkko, Jens Sobek, Dario Neri, 2008, Bioconjugate chemistry.

DRME: Count-based differential RNA methylation analysis at small sample size scenario.

Yufei Huang, Runsheng Chen, Shaowu Zhang, 2016, Analytical biochemistry.

Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library.

Michael A. Stravs, G. Schneider, Tim Geppert, 2012, Chemistry.

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions.

Christoph E. Dumelin, D. Neri, Yixin Zhang, 2008, Bioorganic & medicinal chemistry letters.