Zhao Chen

发表

Non-small-cell lung cancers: a heterogeneous set of diseases

Kwok-Kin Wong, P. Hammerman, Kwok-Kin Wong, 2014, Nature Reviews Cancer.

Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in ALK-Rearranged Non–Small Cell Lung Cancer and Predict Strategies to Overcome Resistance

Kwok-Kin Wong, J. Engelman, N. Sharpless, 2013, Clinical Cancer Research.

Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene.

P. Jänne, Kwok-Kin Wong, N. Gray, 2010, Cancer research.

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

Andrew L. Kung, Matthew D. Wilkerson, Michael D. Cameron, 2012, Nature.

Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer

Travis J Cohoon, Kwok-Kin Wong, J. Qi, 2013, Clinical Cancer Research.

MiR-20a-5pNegativelyRegulatesNR4A3 toPromoteMetastasis in Bladder Cancer

Hai-Su Yang, Zhao Chen, Zhiming Liu, 2021 .

Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.

J. Meyerhardt, Kwok-Kin Wong, J. Engelman, 2011, The Journal of clinical investigation.

Rationale for co-targeting IGF-1R and ALK in ALK fusion positive lung cancer

William Pao, Zhongming Zhao, Ronglai Shen, 2014, Nature Medicine.

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

Kwok-Kin Wong, J. Engelman, R. Bronson, 2009, Proceedings of the National Academy of Sciences.

RMRP Is a Non-Coding RNA Essential for Early Murine Development

W. Hahn, Kwok-Kin Wong, Joseph Rosenbluh, 2011, PloS one.

Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers.

A. Letai, Kwok-Kin Wong, M. Mino‐Kenudson, 2014, Cancer research.

Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

A. Redig, H. Ji, P. Hammerman, 2017, Nature Communications.

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

Shohei Koyama, Kwok-Kin Wong, Hongbin Ji, 2014, Cancer cell.

Non-small-cell lung cancers: a heterogeneous set of diseases

Kwok-Kin Wong, P. Hammerman, Kwok-Kin Wong, 2014, Nature Reviews Cancer.

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.

Travis J Cohoon, D. Hayes, D. Root, 2013, Cancer discovery.

Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells*

Kwok-Kin Wong, N. Bardeesy, A. Tzatsos, 2011, The Journal of Biological Chemistry.

Palbociclib resistance confers dependence on an FGFR-MAP kinase-mTOR-driven pathway in KRAS-mutant non-small cell lung cancer

Kwok-Kin Wong, G. Shapiro, Naveen Kommajosyula, 2018, Oncotarget.

Therapeutics , Targets , and Chemical Biology Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Ef fi cacy of Combined MEK and PI 3 K Inhibitors for KRAS-Mutant Lung Cancers

A. Letai, Kwok-Kin Wong, M. Mino‐Kenudson, 2014 .

Loss of p53 Attenuates the Contribution of IL-6 Deletion on Suppressed Tumor Progression and Extended Survival in Kras-Driven Murine Lung Cancer

Ji-shuai Zhang, Kwok-Kin Wong, X. Tan, 2013, PloS one.

Cancer Therapy : Preclinical Ef fi cacy of BET Bromodomain Inhibition in Kras-Mutant Non – Small Cell Lung Cancer

Junqi, Travis J Cohoon, Kwok-Kin Wong, 2013 .

By targeting TRAF6, miR-140-3p inhibits TGF-β1-induced human osteosarcoma epithelial-to-mesenchymal transition, migration, and invasion

Zhao Chen, N. Zhang, Zixuan Pang, 2020, Biotechnology Letters.

LncRNA PVT1 Promotes Proliferation and Invasion Through Enhancing Smad3 Expression by Sponging MiR-140-5p in Cervical Cancer

Zhao Chen, Shuai Chang, Chun-yan Chen, 2019, Radiology and oncology.

Co-clinical quantitative tumor volume imaging in ALK-rearranged NSCLC treated with crizotinib.

P. Hammerman, Kwok-Kin Wong, H. Hatabu, 2017, European journal of radiology.

Upregulation of IGF1R by Mutant RAS in Leukemia and Potentiation of RAS Signaling Inhibitors by Small-Molecule Inhibition of IGF1R

Kwok-Kin Wong, N. Gray, Qingsong Liu, 2014, Clinical Cancer Research.

Non-small-cell lung cancers: a heterogeneous set of diseases

P. Hammerman, Zhao Chen, Christine M. Fillmore, 2015, Nature Reviews Cancer.

Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies

N. Gray, C. Mitsiades, J. Griffin, 2014, Leukemia.

Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers.

J. Meyerhardt, J. Engelman, J. Settleman, 2011, The Journal of clinical investigation.

Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene.

P. Jänne, N. Gray, G. Adelmant, 2010, Cancer research.

Upregulation of IGF1R by Mutant RAS in Leukemia and Potentiation of RAS Signaling Inhibitors by Small-Molecule Inhibition of IGF1R

N. Gray, Qingsong Liu, C. Mitsiades, 2014, Clinical Cancer Research.