J. Schlachetzki

发表

Gait and Cognition in Parkinson’s Disease: Cognitive Impairment Is Inadequately Reflected by Gait Performance during Dual Task

J. Winkler, K. Pfeifer, S. Steib, 2017, Front. Neurol..

Combined accelerometer and EMG analysis to differentiate essential tremor from Parkinson's disease.

Nooshin Haji Ghassemi, P. Kugler, B. Eskofier, 2016, Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference.

Wearable sensors objectively measure gait parameters in Parkinson’s disease

Samuel J. Reinfelder, K. Aminian, J. Winkler, 2017, PloS one.

Somatic mosaicism reveals clonal distributions of neocortical development

Martin W. Breuss, C. Glass, D. Antaki, 2022, Nature.

Unbiased and Mobile Gait Analysis Detects Motor Impairment in Parkinson's Disease

J. Winkler, J. Hornegger, P. Kugler, 2013, PloS one.

Sensor-based gait analysis of individualized improvement during apomorphine titration in Parkinson’s disease

Zacharias Kohl, Jochen Klucken, Heiko Gaßner, 2018, Journal of Neurology.

Mobile EMG Analysis with Applications in Sport and Medicine

Samuel J. Reinfelder, P. Kugler, B. Eskofier, 2013 .

Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

A. Schneider, M. Bähr, Jochen H Weishaupt, 2008, BMC Neuroscience.

Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity

T. Schäffer, J. Winkler, C. Becker, 2013, Molecular and Cellular Neuroscience.

Incorporation of a nucleoside analog maps genome repair sites in post-mitotic human neurons

Sara B. Linker, Jesse R. Dixon, S. Horvath, 2020, bioRxiv.

Cell type-specific enhancer-promoter connectivity maps in the human brain and disease risk association

F. Gage, Simon T. Schafer, C. Glass, 2019 .

Oligodendroglial α‐synucleinopathy‐driven neuroinflammation in multiple system atrophy

E. Masliah, M. Wegner, J. Winkler, 2019, Brain pathology.

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Timothy A. Miller, Jennifer E. Phillips-Cremins, Lilah M. Besser, 2020, Neuron.

Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis

Nick C Fox, Alan J. Thomas, D. Hernandez, 2020, Scientific Reports.

Increased tyrosine hydroxylase expression accompanied by glial changes within the non-lesioned hemisphere in the 6-hydroxydopamine model of Parkinson's disease.

J. Winkler, B. Winner, F. Marxreiter, 2014, Restorative neurology and neuroscience.

Granulocyte Colony-Stimulating Factor Does Not Promote Neurogenesis after Experimental Intracerebral Haemorrhage

S. Schwab, J. Winkler, J. Schlachetzki, 2014, International journal of stroke : official journal of the International Stroke Society.

Somatic mosaicism in the mature brain reveals clonal cellular distributions during cortical development

Martin W. Breuss, C. Glass, Yan Ding, 2020, bioRxiv.

Mitochondrial Aging Defects Emerge in Directly Reprogrammed Human Neurons due to Their Metabolic Profile.

Baptiste N. Jaeger, F. Gage, J. Mertens, 2018, Cell reports.

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells

E. Masliah, M. Wegner, J. Winkler, 2014, Molecular and Cellular Neuroscience.

Granulocyte‐colony stimulating factor is neuroprotective in a model of Parkinson's disease

Kazuto Kobayashi, Armin Schneider, Paul Lingor, 2006, Journal of neurochemistry.

DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages.

C. Glass, R. Bejar, M. Mokry, 2022, Immunity.

A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice

V. Gradinaru, C. Glass, S. Mazmanian, 2022, bioRxiv.

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.

Nick C. Fox, Pietro Pietrini, Alexander Gerhard, 2018, Nature Medicine.

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Timothy A. Miller, Sonja W. Scholz, Jennifer E. Phillips-Cremins, 2020, Neuron.

The innate immune system in Parkinson's disease: a novel target promoting endogenous neuroregeneration

J. Winkler, J. Schlachetzki, 2015, Neural regeneration research.

Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease

J. Mertens, YongSung Kim, C. Glass, 2022, Cell metabolism.

Human microglia phenotypes in the brain associated with HIV infection

J. Schlachetzki, Yi Zhou, Christopher K Glass, 2022, Current Opinion in Neurobiology.

Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters?

J. Winkler, S. Wiese, J. Schlachetzki, 2017, PloS one.

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

D. Holtzman, O. Harari, M. Colonna, 2022, Neuron.

Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia

B. Fiebich, E. Candelario-Jalil, J. Schlachetzki, 2012, Journal of Neuroinflammation.

Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease.

J. Mertens, C. Glass, D. Galasko, 2022, Cell stem cell.

Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders?

J. Winkler, J. Schlachetzki, B. Ettle, 2015, Molecular Neurobiology.

Microbiome–microglia connections via the gut–brain axis

C. Glass, S. Mazmanian, J. Schlachetzki, 2018, The Journal of experimental medicine.

Varicella zoster virus cerebellitis in a 66-year-old patient without herpes zoster

M. Bähr, R. Nau, J. Schlachetzki, 2006, The Lancet.

Brain cell type–specific enhancer–promoter interactome maps and disease-risk association

James B. Brewer, Fred H. Gage, Bing Ren, 2019, Science.

An environment-dependent transcriptional network specifies human microglia identity

Baptiste N. Jaeger, C. Glass, R. Ransohoff, 2017, Science.

Paradoxical kinesia in Parkinson's disease revisited: Anticipation of temporal constraints is critical

T. Schenk, J. Winkler, Z. Kohl, 2016, Neuropsychologia.

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity.

C. Glass, F. Geissmann, Zhengyu Ouyang, 2019, Immunity.

Monosodium Urate Crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

C. Glass, R. Terkeltaub, R. Liu-Bryan, 2021, bioRxiv.

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients

S. Horvath, F. Gage, J. Mertens, 2021, Cell stem cell.

Human microglia phenotypes in the brain associated with HIV infection

J. Schlachetzki, Yi Zhou, Christopher K Glass, 2022, Current Opinion in Neurobiology.

Alpha-synuclein activates BV2 microglia dependent on its aggregation state.

J. Winkler, J. Schlachetzki, A. Kulinich, 2016, Biochemical and biophysical research communications.

Nuclei isolation of multiple brain cell types for omics interrogation

C. Glass, J. Schlachetzki, A. Nott, 2021, Nature Protocols.

Interleukin-33 coordinates a microglial phagocytic response and limits corticothalamic excitability and seizure susceptibility

C. Glass, J. Paz, A. Molofsky, 2021, bioRxiv.

Gene regulatory networks underlying human microglia maturation

C. Glass, L. Laurent, M. Levy, 2021, bioRxiv.

Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes

Nick C Fox, Alan J. Thomas, D. Hernandez, 2021, Biological Psychiatry.

A monocyte gene expression signature in the early clinical course of Parkinson’s disease

C. Glass, J. Winkler, B. Winner, 2018, Scientific Reports.

Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System.

C. Glass, J. Winkler, Zhengyu Ouyang, 2020, Cell reports.

Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons

Sara B. Linker, Jesse R. Dixon, S. Horvath, 2021, Science.

Long-term course of anterior spinal cord herniation presenting with an upper motor neuron syndrome: case report illustrating diagnostic and therapeutic implications

A. Doerfler, J. Winkler, J. Schlachetzki, 2020, BMC Neurology.

Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies

E. Masliah, J. Winkler, M. Riemenschneider, 2017, Neural plasticity.

Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS

E. Haan, P. Pietrini, R. Petersen, 2017, Scientific Reports.

D. Hernandez, M. Nalls, L. Ferrucci, 2017, bioRxiv.

Frontotemporal dementia and its subtypes: a genome-wide association study

Alexander Gerhard, Adrian Danek, Luigi Ferrucci, 2014, The Lancet Neurology.

Microglia in Alzheimer's Disease.

J. Schlachetzki, P. Süß, 2020, Current Alzheimer research.

Microglial activation in Alzheimer's disease.

M. Hüll, J. Schlachetzki, 2009, Current Alzheimer research.

Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity

U. Schlötzer-Schrehardt, J. Winkler, C. Becker, 2015, Molecular Neurodegeneration.

Hippocampal structure and function are maintained despite severe innate peripheral inflammation

J. Kornhuber, J. Winkler, G. Schett, 2015, Brain, Behavior, and Immunity.

When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging neuron

J. Mertens, J. Schlachetzki, T. Toda, 2020, Experimental Gerontology.

Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia

M. Hüll, B. Fiebich, M. Heneka, 2010, Journal of Neuroinflammation.

The Joint-Brain Axis: Insights From Rheumatoid Arthritis on the Crosstalk Between Chronic Peripheral Inflammation and the Brain

J. Winkler, J. Schlachetzki, P. Süß, 2020, Frontiers in Immunology.

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.

Nick C Fox, Alan J. Thomas, D. Hernandez, 2018, Nature Medicine.

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

Nick C Fox, Alan J. Thomas, D. Hernandez, 2018, Brain : a journal of neurology.

Increase of Reproductive Life Span Delays Age of Onset of Parkinson’s Disease

J. Winkler, J. Klucken, J. Schlachetzki, 2017, Front. Neurol..

Combined accelerometer and EMG analysis to differentiate essential tremor from Parkinson's disease

Björn Eskofier, Patrick Kugler, Jochen Klucken, 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy

Fred H. Gage, Tobias Bäuerle, Arif B. Ekici, 2016, Acta Neuropathologica.

Chronic peripheral inflammation: a possible contributor to neurodegenerative diseases

J. Schlachetzki, Addison J. Lana, Patrick Süβ, 2021, Neural regeneration research.

Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice

S. Schwab, J. Winkler, B. Winner, 2016, Front. Neurosci..

Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS

Nick C Fox, D. Hernandez, M. Nalls, 2017, Scientific Reports.

Intracerebroventricular Administration of Nerve Growth Factor Induces Gliogenesis in Sensory Ganglia, Dorsal Root, and within the Dorsal Root Entry Zone

J. Winkler, D. Pizzo, J. Schlachetzki, 2014, BioMed research international.

Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity

U. Schlötzer-Schrehardt, J. Winkler, C. Becker, 2015, Molecular Neurodegeneration.

Dopaminergic lesioning impairs adult hippocampal neurogenesis by distinct modification of α‐synuclein

J. Winkler, B. Winner, J. Schlachetzki, 2016, Journal of neuroscience research.

From sweet to sweat: Hedonic olfactory range is impaired in Parkinson's disease.

T. Schenk, J. Winkler, Z. Kohl, 2016, Parkinsonism & related disorders.

Characterization of sphingosine-1-phosphate and its receptors in Parkinson's disease – Is there a link?

J. Winkler, B. Winner, J. Schlachetzki, 2013 .

Promoting oligodendrocyte progenitor cell maturation and remyelination as a novel therapeutical approach for multiple system atrophy

J. Winkler, J. Schlachetzki, B. Ettle, 2014 .

An in vivo neuroimmune organoid model to study human microglia phenotypes

A. Nimmerjahn, Simon T. Schafer, Monique Pena, 2023, Cell.

Automatic recognition of Parkinson's disease using surface electromyography during standardized gait tests

Björn Eskofier, Patrick Kugler, Christian Jaremenko, 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

Human microglia maturation is underpinned by specific gene regulatory networks.

Jennifer F. Hughes, L. Laurent, Carolyn O’Connor, 2023, Immunity.

CXCR4 involvement in neurodegenerative diseases

O. Andreassen, G. Schellenberg, A. Dale, 2017, bioRxiv.

Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice

J. Paz, A. Molofsky, J. Schlachetzki, 2022, The Journal of experimental medicine.

APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

Ian H. Guldner, Róbert Pálovics, E. Reiman, 2023, bioRxiv.

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

P. Pietrini, R. Desikan, J. Trojanowski, 2019, Scientific Reports.

Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management

J. Schlachetzki, M. Marquine, J. Fields, 2023, Nature Reviews Neurology.