S. Oishi

发表

Neuropeptide derivatives to regulate the reproductive axis: Kisspeptin receptor (KISS1R) ligands and neurokinin‐3 receptor (NK3R) ligands

N. Fujii, S. Oishi, 2016, Biopolymers.

Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4).

N. Fujii, S. Oishi, 2012, Organic & biomolecular chemistry.

Convergent synthesis of (-)-quinocarcin based on the combination of Sonogashira coupling and gold(I)-catalyzed 6-endo-dig hydroamination.

N. Fujii, H. Ohno, S. Oishi, 2013, Chemistry.

Novel antiviral activity of bromocriptine against dengue virus replication.

S. Tajima, Takeshi Kobayashi, S. Vasudevan, 2016, Antiviral research.

Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries.

Stephen C Peiper, Satoshi Ueda, Shinya Oishi, 2003, Angewandte Chemie.

Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: synthetic study of laurendecumallene B.

N. Fujii, H. Ohno, S. Oishi, 2013, Organic letters.

Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation.

N. Fujii, H. Ohno, S. Oishi, 2015, Chemistry.

Metastin and its variant forms suppress migration of pancreatic cancer cells.

J. Broach, M. Imamura, T. Masui, 2004, Biochemical and biophysical research communications.

Clinical significance of plasma metastin level in pancreatic cancer patients.

R. Doi, N. Fujii, Fumihiko Katagiri, 2009, Oncology reports.

Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress.

Katsunori Tanaka, N. Taniguchi, S. Kitazume, 2014, Organic & biomolecular chemistry.

Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182.

M. Matsuoka, N. Fujii, H. Ohno, 2013, Bioorganic & medicinal chemistry.

Concise synthesis and anti-HIV activity of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic heterocycles.

M. Matsuoka, N. Fujii, H. Ohno, 2012, Organic & biomolecular chemistry.

Structure-activity relationship study of pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives for potent anti-HIV agents.

M. Matsuoka, N. Fujii, H. Ohno, 2012, Bioorganic & medicinal chemistry.

A simple, rapid, and sensitive system for the evaluation of anti-viral drugs in rats.

M. Matsuoka, N. Fujii, E. Kodama, 2012, Biochemical and biophysical research communications.

Structure-activity relationship study of phenylpyrazole derivatives as a novel class of anti-HIV agents.

M. Matsuoka, Takayuki Kato, N. Fujii, 2013, Bioorganic & medicinal chemistry letters.

Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus.

M. Matsuoka, H. Tsujimoto, N. Fujii, 2009, Bioorganic & medicinal chemistry.

Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread.

M. Matsuoka, N. Fujii, S. Oishi, 2015, Virology.

Total synthesis of odoamide, a novel cyclic depsipeptide, from an Okinawan marine cyanobacterium.

N. Fujii, H. Ohno, S. Oishi, 2016, Organic & biomolecular chemistry.

Synthesis of IB-01212 by multiple N-methylations of peptide bonds.

N. Fujii, H. Ohno, S. Oishi, 2014, Bioorganic & medicinal chemistry.

A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression.

N. Kadowaki, J. Kanda, N. Fujii, 2015, Experimental hematology.

The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: roles of receptor domains.

D. Sinnett, R. Leduc, N. Heveker, 2010, The Journal of biological chemistry.

Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides

A. Asai, A. Otaka, H. Tamamura, 2006 .

Access to Indole-Fused Benzannulated Medium-Sized Rings through Gold(I)-Catalyzed Cascade Cyclization of Azido-Alkynes.

H. Ohno, S. Oishi, A. Hashmi, 2021, Chemistry.

Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model.

E. Schwarz, Hiromu Ito, N. Fujii, 2009, Arthritis and rheumatism.

Concise synthesis of indole-fused 1,4-diazepines through copper(I)-catalyzed domino three-component coupling-cyclization-N-arylation under microwave irradiation.

N. Fujii, H. Ohno, S. Oishi, 2008, Organic letters.

Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic.

R. Fisher, T. Burke, M. Nicklaus, 2005, Bioorganic & medicinal chemistry letters.

Synthesis of Triazolo- and Oxadiazolopiperazines by Gold(I)-Catalyzed Domino Cyclization: Application to the Design of a Mitogen Activated Protein (MAP) Kinase Inhibitor.

H. Ohno, M. Ohue, S. Oishi, 2018, Organic letters.

Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor.

N. Fujii, H. Nakashima, S. Oishi, 2015, Biochemical and biophysical research communications.

Electrostatically constrained alpha-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide.

M. Matsuoka, A. Otaka, Yuji Kobayashi, 2009, The international journal of biochemistry & cell biology.

Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.

H. Tamamura, N. Fujii, S. Oishi, 2007, Biopolymers.

A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging.

H. Saji, K. Sano, N. Fujii, 2014, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors.

N. Fujii, S. Oishi, H. Kakeya, 2015, Bioorganic & medicinal chemistry.

Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors.

G. Tsujimoto, N. Fujii, H. Ohno, 2013, Organic & biomolecular chemistry.

Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo αvβ3 integrin related tumor imaging

Kengo Ito, K. Hatano, H. Saji, 2003 .

Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions.

N. Fujii, H. Ohno, S. Oishi, 2007, Angewandte Chemie.

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

E. Buss, P. Frenette, H. Broxmeyer, 2011, Leukemia.

Structure-activity relationships of carboline and carbazole derivatives as a novel class of ATP-competitive kinesin spindle protein inhibitors.

K. Kitaura, K. Matsuno, A. Asai, 2011, Journal of medicinal chemistry.

Cu(II)-mediated oxidative intermolecular ortho C-H functionalisation using tetrahydropyrimidine as the directing group.

N. Fujii, H. Ohno, S. Oishi, 2009, Chemical communications.

Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to κ-Opioid Receptor.

N. Fujii, H. Ohno, S. Oishi, 2016, Chemical & pharmaceutical bulletin.

Total Synthesis of Dictyodendrins A-F by the Gold-Catalyzed Cascade Cyclization of Conjugated Diyne with Pyrrole.

Y. Miyamoto, M. Oka, H. Ohno, 2020, Chemistry.

SmI2-Mediated Reduction of γ,γ-Difluoro-α,β-enoates with Application to the Synthesis of Functionalized (Z)-Fluoroalkene-Type Dipeptide Isosteres

T. Kinoshita, A. Otaka, H. Tamamura, 2004 .

Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands.

G. Tsujimoto, S. Ohkura, N. Inoue, 2011, ACS medicinal chemistry letters.

Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase.

N. Fujii, H. Ohno, S. Oishi, 2008, Journal of medicinal chemistry.

Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat.

M. Matsuoka, S. Uchiyama, Yuji Kobayashi, 2010, Antiviral research.

Gold(I)-Catalyzed Cascade Cyclization Reactions of Allenynes for the Synthesis of Fused Cyclopropanes and Acenaphthenes.

H. Ohno, S. Oishi, S. Inuki, 2019, Angewandte Chemie.

Gold(I)-Catalyzed Cascade Cyclization Reactions of Allenynes for the Synthesis of Fused Cyclopropanes and Acenaphthenes.

H. Ohno, S. Oishi, S. Inuki, 2019, Angewandte Chemie.

Chronic Peripheral Administration of Kappa-Opioid Receptor Antagonist Advances Puberty Onset Associated with Acceleration of Pulsatile Luteinizing Hormone Secretion in Female Rats

A. Iwase, F. Kikkawa, N. Fujii, 2013, The Journal of reproduction and development.

Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows

S. Ohkura, F. Matsuda, N. Fujii, 2013, The Journal of reproduction and development.

Novel screening systems for HIV-1 fusion mediated by two extra-virion heptad repeats of gp41

M. Matsuoka, N. Fujii, Hiroki Nishikawa, 2008, Antiviral Research.

Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus.

H. Tsujimoto, H. Tamamura, N. Fujii, 2009, The Journal of veterinary medical science.

Antiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein.

H. Tsujimoto, N. Fujii, S. Oishi, 2009, Veterinary Microbiology.

Design of a novel HIV-1 fusion inhibitor that displays a minimal interface for binding affinity.

M. Matsuoka, N. Fujii, H. Ohno, 2008, Journal of medicinal chemistry.

Stromal Cell-Derived Factor 1 Regulates the Actin Organization of Chondrocytes and Chondrocyte Hypertrophy

Takashi Nakamura, Hiromu Ito, N. Fujii, 2012, PloS one.

Design and synthesis of amidine-type peptide bond isosteres: application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis.

N. Fujii, H. Ohno, M. Nomizu, 2011, Organic & biomolecular chemistry.

Structure-activity relationship studies on cyclic RGD peptides utilizing novel alkene dipeptide isosteres.

S. Oishi, 2004, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design.

S. Sarafianos, M. Matsuoka, N. Fujii, 2013, The international journal of biochemistry & cell biology.

Paradoxical downregulation of CXC chemokine receptor 4 induced by polyphemusin II-derived antagonists.

G. Tsujimoto, N. Fujii, H. Ohno, 2012, Bioconjugate chemistry.

Structure-activity relationship study of a CXC chemokine receptor type 4 antagonist, FC131, using a series of alkene dipeptide isosteres.

N. Fujii, H. Ohno, T. Furuya, 2012, Journal of medicinal chemistry.

Synthesis and evaluation of a bimodal CXCR4 antagonistic peptide.

N. S. van den Berg, L. Josephson, N. Fujii, 2011, Bioconjugate chemistry.

Potent CXCR4 antagonists containing amidine type Peptide bond isosteres.

M. Matsuoka, N. Fujii, H. Ohno, 2011, ACS medicinal chemistry letters.

Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors.

A. Asai, J. Sawada, N. Fujii, 2014, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

K. Matsuno, A. Asai, J. Sawada, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and Application of Fluorescein‐ and Biotin‐Labeled Molecular Probes for the Chemokine Receptor CXCR4

G. Tsujimoto, M. Matsuoka, N. Fujii, 2008, Chembiochem : a European journal of chemical biology.

Non-invasive longitudinal imaging of tumor progression using an (111)indium labeled CXCR4 peptide antagonist.

A. Borowsky, J. Wesseling, N. Fujii, 2012, American journal of nuclear medicine and molecular imaging.

Longitudinal imaging of CXCR 4 1 Non-invasive longitudinal imaging of tumor progression using an 111 Indium labeled CXCR 4 peptide antagonist

A. Borowsky, J. Wesseling, N. Fujii, 2011 .

Corrigendum to “conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity”: [Bioorg. Med. Chem. Lett. 11 (2001) 359]

Y. Kan, A. Otaka, H. Tamamura, 2001 .

Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity.

Y. Kan, A. Otaka, H. Tamamura, 2001, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro evaluation of a bimodal CXCR4 antagonistic peptide

N. Fujii, Hushan Yuan, S. Oishi, 2013 .

CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner

E. Solary, W. Vainchenker, G. Barosi, 2016, Oncotarget.

CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice.

N. Fujii, Y. Omatsu, S. Oishi, 2011, Blood.

Visible quantum cutting through downconversion in KLiGdF5:Eu3+ crystals

S. Oishi, N. Kodama, 2005 .

Direct synthesis of aryl-annulated [c]carbazoles by gold(i)-catalysed cascade reaction of azide-diynes and arenes.

H. Ohno, S. Oishi, Misaki Kobayashi, 2018, Chemical science.

Structure‐activity relationship study and NMR analysis of fluorobenzoyl pentapeptide GPR54 agonists

N. Fujii, H. Ohno, S. Oishi, 2008, Biopolymers.

SB223412, a neurokinin-3 receptor-selective antagonist, suppresses testosterone secretion in male guinea pigs.

F. Matsuda, S. Oishi, H. Tsukamura, 2017, Theriogenology.

Establishment and clinical application of enzyme immunoassays for determination of luteinizing hormone releasing hormone and metastin

N. Fujii, Fumihiko Katagiri, S. Oishi, 2007, Journal of peptide science : an official publication of the European Peptide Society.

Structure-activity relationship study on small peptidic GPR54 agonists.

N. Fujii, H. Ohno, S. Oishi, 2006, Bioorganic & medicinal chemistry.

Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity.

J. Broach, A. Otaka, H. Tamamura, 2006, Bioorganic & medicinal chemistry letters.

HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains

S. Sarafianos, M. Matsuoka, N. Fujii, 2013, Antimicrobial Agents and Chemotherapy.

Title A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo

K. Hashimoto, Y. Kawasaki, N. Fujii, 2018 .

A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo

M. Hosoya, K. Hashimoto, Y. Kawasaki, 2016, PloS one.

Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method

N. Fujii, M. Kaku, E. Kodama, 2015, Antiviral chemistry & chemotherapy.

Potent Anti-HIV-1 Activity of N-HR-Derived Peptides Including a Deep Pocket-Forming Region without Antagonistic Effects on T-20

S. Sarafianos, M. Matsuoka, N. Fujii, 2011, Antiviral chemistry & chemotherapy.

Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants

M. Matsuoka, A. Asai, N. Fujii, 2010 .

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of alpha-helical anti-HIV peptide analogues.

M. Matsuoka, T. Narumi, N. Fujii, 2009, Organic & biomolecular chemistry.

The metastasis suppressor KISS1 lacks antimetastatic activity in the C8161.9 xenograft model of melanoma

N. Fujii, S. Oishi, S. Peiper, 2012, Melanoma research.

Odoamide, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Okeania sp.

N. Fujii, S. Oishi, K. Suenaga, 2016 .

Construction of linked nitrogen heterocycles by palladium(0)-catalyzed intramolecular domino cyclization of 2-alkynylaziridines bearing a 2-aminoethyl group via ring expansion with isocyanate.

N. Fujii, H. Ohno, S. Oishi, 2010, The Journal of organic chemistry.

Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study.

A. Otaka, H. Tamamura, N. Fujii, 2002, Bioorganic & medicinal chemistry.

Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety.

A. Otaka, H. Tamamura, N. Fujii, 2002, Bioorganic & medicinal chemistry letters.

Direct construction of fused indoles by gold-catalyzed cascade cyclization of conjugated diynes.

N. Fujii, H. Ohno, S. Oishi, 2015, Organic letters.

Structure‐Activity Relationships of Pyrazine‐Based CK2 Inhibitors: Synthesis and Evaluation of 2,6‐Disubstituted Pyrazines and 4,6‐Disubstituted Pyrimidines

Takafumi Hara, G. Tsujimoto, N. Fujii, 2008, Archiv der Pharmazie.

Concise site-specific synthesis of DTPA-peptide conjugates: application to imaging probes for the chemokine receptor CXCR4.

H. Saji, N. Fujii, H. Kimura, 2011, Bioorganic & medicinal chemistry.

Biological activities of homologous loop regions in the laminin alpha chain G domains.

A. Utani, H. Kleinman, N. Fujii, 2003, The Journal of biological chemistry.

The natural flavonoid myricetin inhibits gastric H+, K+‐ATPase

H. Takeshima, A. Ichimura, S. Oishi, 2018, European journal of pharmacology.

Structure-activity relationship study on polyglutamine binding peptide QBP1.

N. Fujii, H. Ohno, T. Toda, 2009, Bioorganic & medicinal chemistry.

Synthesis of jaspine B regioisomers through palladium-catalyzed stereoselective tetrahydrofuran formation: Insight into the ligand recognition of sphingosine kinases

N. Fujii, H. Ohno, I. Nakanishi, 2018 .

Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure-activity relationship study of 4-epi-jaspine B.

N. Fujii, H. Ohno, I. Nakanishi, 2017, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres.

M. Matsuoka, T. Narumi, N. Fujii, 2010, Organic & biomolecular chemistry.

Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids.

T. Narumi, H. Tamamura, N. Fujii, 2009, Organic & biomolecular chemistry.

Identification of novel non-peptide CXCR4 antagonists by ligand-based design approach.

M. Matsuoka, H. Nagasawa, N. Fujii, 2008, Bioorganic & medicinal chemistry letters.

Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: a receptor for human placental infection.

B. Gamain, N. Fujii, S. Oishi, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta3 integrin related tumor imaging.

Kengo Ito, K. Hatano, H. Saji, 2003, Nuclear medicine and biology.

Peripheral administration of κ-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats.

S. Ohkura, T. Yamamura, F. Matsuda, 2019, Domestic animal endocrinology.

Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1.

A. Otaka, N. Fujii, S. Oishi, 2006, Organic letters.

Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins

W. Vogel, S. Oishi, K. McPhail, 2019, ACS chemical biology.

Ring‐Closing Metathesis of C‐Terminal Allylglycine Residues with an N‐Terminal β‐Vinyl‐Substituted Phosphotyrosyl Mimetic as an Approach to Novel Grb2 SH2 Domain‐Binding Macrocycles

R. Fisher, T. Burke, S. Oishi, 2005, Chembiochem : a European journal of chemical biology.

Design and synthesis of fluorescent probes for GPR54.

N. Fujii, H. Ohno, A. Hirasawa, 2014, Bioorganic & medicinal chemistry.

Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists.

N. Fujii, H. Ohno, T. Noguchi, 2013, Bioorganic & medicinal chemistry.

Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus)

N. Inoue, N. Fujii, Y. Ohmori, 2011, Proceedings of the National Academy of Sciences.

High Affinity Grb2 SH2 Domain-Binding Macrocycles Derived from Ring-Closing Methathesis of Alkenylglyicne Residues with β-Vinyl Phosphotyrosyl Mimetics

R. Fisher, Fa Liu, T. Burke, 2006 .

Synthesis and application of an Nδ-acetyl-Nδ-hydroxyornithine analog: identification of novel metal complexes of deferriferrichrysin.

N. Fujii, H. Ohno, Y. Hata, 2012, Bioorganic & medicinal chemistry.

The Effect of Kisspeptin Receptor Agonist (FTM080) on Luteinizing Hormone in Sheep

N. Fujii, S. Oishi, B. Whitlock, 2011 .

Development of Mirror-Image Screening Systems for XIAP BIR3 Domain Inhibitors.

N. Fujii, H. Ohno, S. Oishi, 2019, Bioconjugate chemistry.

Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors.

T. Kinoshita, N. Fujii, H. Ohno, 2016, Bioorganic & medicinal chemistry.

Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles.

H. Ohno, S. Oishi, Junpei Matsuoka, 2017, Angewandte Chemie.

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

E. Buss, P. Frenette, M. Tesio, 2011, Leukemia.

Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides.

N. Fujii, H. Ohno, S. Oishi, 2015, Organic letters.

Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of indoloquinolines.

N. Fujii, H. Ohno, S. Oishi, 2014, Organic letters.

Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes.

N. Fujii, H. Ohno, S. Oishi, 2012, The Journal of organic chemistry.

Gold(I)-catalyzed polycyclizations of polyenyne-type anilines based on hydroamination and consecutive hydroarylation cascade.

N. Fujii, H. Ohno, S. Oishi, 2011, The Journal of organic chemistry.

Gold‐Catalyzed Intramolecular Alkyne Cycloisomerization Cascade: Direct Synthesis of Aryl‐Annulated[a]carbazoles from Aniline‐Substituted Diethynylarenes

N. Fujii, H. Ohno, S. Oishi, 2010 .

High-throughput turbidimetric screening for heparin-neutralizing agents and low-molecular-weight heparin mimetics.

T. Koide, N. Fujii, S. Oishi, 2012, Chemical & pharmaceutical bulletin.

Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds.

M. Matsuoka, N. Fujii, H. Ohno, 2015, Organic & biomolecular chemistry.

Peptide and Peptidomimetic Ligands for CXC Chemokine Receptor 4 (CXCR4)

N. Fujii, S. Oishi, 2012 .

Efficient synthesis of aminomethylated azaindoles and corresponding pyrrole-fused derivatives by copper-catalyzed domino multicomponent coupling and cyclization

N. Fujii, H. Ohno, S. Oishi, 2012 .

Direct synthesis of fused indoles by gold-catalyzed cascade cyclization of diynes.

N. Fujii, H. Ohno, S. Oishi, 2011, The Journal of organic chemistry.

Rapid access to 3-(aminomethyl)isoquinoline-fused polycyclic compounds by copper-catalyzed four-component coupling, cascade cyclization, and oxidation.

N. Fujii, T. Watabe, H. Ohno, 2009, The Journal of organic chemistry.

Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines.

N. Fujii, H. Ohno, S. Oishi, 2010, Organic letters.

Palladium-catalyzed direct synthesis of carbazoles via one-pot N-arylation and oxidative biaryl coupling: synthesis and mechanistic study.

N. Fujii, H. Ohno, S. Oishi, 2009, The Journal of organic chemistry.

One‐Pot Synthesis of Carbazoles by Palladium‐Catalyzed N‐Arylation and Oxidative Coupling.

N. Fujii, H. Ohno, S. Oishi, 2008 .

Direct synthesis of highly fused perimidines by copper(I)-catalyzed hydroamination of 2-ethynylbenzaldehydes

N. Fujii, H. Ohno, S. Oishi, 2011 .

Palladium-catalyzed sp(3) CH activation of simple alkyl groups: direct preparation of indoline derivatives from N-alkyl-2-bromoanilines.

N. Fujii, H. Ohno, S. Oishi, 2008, Organic letters.

Facile synthesis of fluoroalkenes by palladium-catalyzed reductive defluorination of allylic gem-difluorides.

T. Narumi, N. Fujii, H. Ohno, 2007, Organic letters.

One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling.

Satoshi Ueda, Shinya Oishi, N. Fujii, 2007, Chemical communications.

Construction of Quaternary Carbon Stereocenter of α-Tertiary Amine through Remote C-H Functionalization of Tris Derivatives: Enantioselective Total Synthesis of Myriocin.

H. Ohno, S. Oishi, S. Inuki, 2019, Organic letters.

A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor.

H. Nishiyama, O. Ogawa, N. Fujii, 2010, The Journal of urology.

Synthesis of fused and linked bicyclic nitrogen heterocycles by palladium-catalyzed domino cyclization of propargyl bromides.

N. Fujii, H. Ohno, S. Oishi, 2010, Chemistry.

Gold-catalyzed three-component annulation: efficient synthesis of highly functionalized dihydropyrazoles from alkynes, hydrazines, and aldehydes or ketones.

N. Fujii, H. Ohno, S. Oishi, 2012, Organic letters.

Total Synthesis of Zephycarinatines via Photocatalytic Reductive Radical ipso ‐Cyclization

A. Ichimura, H. Ohno, S. Oishi, 2020, Angewandte Chemie.

Total Synthesis of Zephycarinatines via Photocatalytic Reductive Radical ipso-Cyclization.

A. Ichimura, H. Ohno, S. Oishi, 2020, Angewandte Chemie.

Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds.

A. Asai, J. Sawada, N. Fujii, 2010, Journal of medicinal chemistry.

Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization.

N. Fujii, H. Ohno, S. Oishi, 2009, The Journal of organic chemistry.

Efficient synthesis of pyrimido[1,2-c] [1,3]benzothiazin-6-imines and related tricyclic heterocycles by S(N)Ar-type C-S, C-N, or C-O bond formation with heterocumulenes.

N. Fujii, H. Ohno, S. Oishi, 2010, The Journal of organic chemistry.

Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation.

N. Fujii, H. Ohno, S. Oishi, 2014, Chemical communications.

Synthesis of Fused Carbazoles by Gold-Catalyzed Tricyclization of Conjugated Diynes via Rearrangement of an N-Propargyl Group.

N. Fujii, H. Ohno, S. Oishi, 2015, Organic letters.

Structure-based design of novel potent protein kinase CK2 (CK2) inhibitors with phenyl-azole scaffolds.

Kazuo Kitaura, Shinya Oishi, Gozoh Tsujimoto, 2012, Journal of medicinal chemistry.

Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation.

N. Fujii, H. Ohno, S. Oishi, 2008, Chemical communications.

Total synthesis of (-)-quinocarcin by gold(I)-catalyzed regioselective hydroamination.

Shinya Oishi, Hiroaki Chiba, N. Fujii, 2012, Angewandte Chemie.

Gold-Catalyzed Cascade Cyclization of 2-Alkynyl-N-Propargylanilines by Rearrangement of a Propargyl Group.

N. Fujii, H. Ohno, S. Oishi, 2015, Angewandte Chemie.

Fmoc-based solid-phase synthesis of GPR54-agonistic pentapeptide derivatives containing alkene- and fluoroalkene-dipeptide isosteres.

T. Narumi, N. Fujii, H. Ohno, 2007, Biopolymers.

Diastereoselective synthesis of new psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics.

A. Otaka, H. Tamamura, N. Fujii, 2002, The Journal of organic chemistry.

Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres

A. Otaka, Y. Miwa, H. Tamamura, 2002 .

Versatile use of acid-catalyzed ring-opening of β-aziridinyl-α,β-enoates to stereoselective synthesis of peptidomimetics

H. Tamamura, N. Fujii, S. Oishi, 2007 .

Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu

A. Otaka, H. Tamamura, N. Fujii, 2001 .

Design and synthesis of a novel class of CK2 inhibitors: application of copper- and gold-catalysed cascade reactions for fused nitrogen heterocycles.

G. Tsujimoto, N. Fujii, H. Ohno, 2012, Organic & biomolecular chemistry.

Facile synthesis of 1,2,3,4-tetrahydro-beta-carbolines by one-pot domino three-component indole formation and nucleophilic cyclization.

N. Fujii, H. Ohno, S. Oishi, 2009, Organic letters.

Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides

N. Fujii, H. Ohno, S. Oishi, 2015 .

Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of propargyl chlorides and carbonates.

N. Fujii, H. Ohno, S. Oishi, 2010, The Journal of organic chemistry.

Efficient synthesis of aminomethylated pyrroloindoles and dipyrrolopyridines via controlled copper-catalyzed domino multicomponent coupling and bis-cyclization.

N. Fujii, H. Ohno, S. Oishi, 2009, The Journal of organic chemistry.

Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP).

A. Asai, J. Sawada, N. Fujii, 2016, Bioorganic & medicinal chemistry letters.

Concise Synthesis of Indole-Fused 1,4-Diazepines Through Copper(I)-Catalyzed Domino Three-Component Coupling—Cyclization—N-Arylation under Microwave Irradiation.

N. Fujii, H. Ohno, S. Oishi, 2008 .

Regio- and Stereoselective Synthesis of (E)-Alkene trans-Xaa-Pro Dipeptide Mimetics Utilizing Organocopper-Mediated Anti-SN2‘ Reactions

T. Kinoshita, A. Otaka, H. Tamamura, 2002 .

Enantioselective total synthesis of (+)-lysergic acid, (+)-lysergol, and (+)-isolysergol by palladium-catalyzed domino cyclization of allenes bearing amino and bromoindolyl groups.

N. Fujii, H. Ohno, S. Oishi, 2011, The Journal of organic chemistry.

Diastereoselective synthesis of psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type dipeptide isosteres by organocopper-mediated anti-S(N)2' reaction.

A. Otaka, H. Tamamura, N. Fujii, 2002, Organic letters.

Gold(I)-Catalyzed Cascade Cyclization of Anilines with Diynes: Controllable Formation of Eight-Membered Ring-Fused Indoles and Propellane-Type Indolines.

H. Ohno, S. Oishi, S. Inuki, 2020, The Journal of organic chemistry.

Gold-catalyzed hydroarylation of allenes: a highly regioselective carbon-carbon bond formation producing six-membered rings.

N. Fujii, H. Ohno, S. Oishi, 2007, Organic letters.

Formal Total Synthesis of (±)-Strictamine Based on a Gold-Catalyzed Cyclization.

N. Fujii, H. Ohno, S. Oishi, 2016, Organic letters.

Novel synthesis of chiral terminal allenes via palladium(0)-catalyzed reduction of mesylates of 2-bromoalk-2-en-1-ols bearing a protected amino group, using diethylzinc

N. Fujii, H. Ohno, S. Oishi, 2000 .

Formal total synthesis of (+)-lysergic acid via zinc(II)-mediated regioselective ring-opening reduction of 2-alkynyl-3-indolyloxirane.

N. Fujii, H. Ohno, S. Oishi, 2011, The Journal of organic chemistry.

Gold(I)-Catalyzed Oxidative Cascade Cyclization of 1,4-Diyn-3-ones for the Construction of Tropone-Fused Furan Scaffolds.

H. Ohno, S. Oishi, S. Inuki, 2018, Organic letters.

Design and synthesis of all diastereomers of cyclic pseudo-dipeptides as mimics of cyclic CXCR4 pentapeptide antagonists.

N. Fujii, H. Ohno, S. Oishi, 2007, Organic & biomolecular chemistry.

Gold-Catalyzed Atom-Economical Cascade Reactions of Alkynes for Ring Formation

N. Fujii, H. Ohno, S. Oishi, 2014 .

Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic

T. Narumi, N. Fujii, H. Ohno, 2008 .

Diastereoselective synthesis of psi[(E)-CMe=CH]- and psi[(E)-CMe=CMe]- type dipeptide isosteres based on organocopper-mediated anti-S(N)2' reaction.

A. Otaka, H. Tamamura, N. Fujii, 2002, Organic letters.

Total synthesis of (+/-)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group.

N. Fujii, H. Ohno, S. Oishi, 2008, Organic letters.

Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic.

Marc C Nicklaus, Shinya Oishi, Robert J Fisher, 2005, Bioorganic & medicinal chemistry.

Lewis-acid-mediated ring-exchange reaction of dihydrobenzofurans and its application to the formal total synthesis of (−)-quinocarcinamide

N. Fujii, H. Ohno, S. Oishi, 2012 .

Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne.

N. Fujii, H. Ohno, Y. Yoshida, 2016, The Journal of organic chemistry.

Palladium-catalyzed sp(3) CH activation of simple alkyl groups: direct preparation of indoline derivatives from N-alkyl-2-bromoanilines.

N. Fujii, H. Ohno, S. Oishi, 2008, Organic letters.

Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system.

N. Fujii, H. Ohno, S. Oishi, 2002, The Journal of organic chemistry.

Targeting of HER/ErbB family proteins using broad spectrum Sec61 inhibitors coibamide A and apratoxin A.

M. Moasser, C. Badr, S. Oishi, 2020, Biochemical pharmacology.

Fe(ii)-Complexation of tripodal hexapeptide ligands with three bidentate triazolylpyridines: induction of metal-centred chirality by peptide macrocyclization.

T. Kameda, N. Fujii, H. Ohno, 2017, Dalton transactions.

Synthesis and functional analysis of deferriferrichrysin derivatives: application to colorimetric pH indicators.

N. Fujii, H. Ohno, Y. Hata, 2013, Bioorganic & medicinal chemistry.

Use of a Compact Tripodal Tris(bipyridine) Ligand to Stabilize a Single-Metal-Centered Chirality: Stereoselective Coordination of Iron(II) and Ruthenium(II) on a Semirigid Hexapeptide Macrocycle.

T. Kameda, H. Ohno, S. Oishi, 2018, Inorganic Chemistry.

Head-to-tail macrocyclization of cysteine-free peptides using an o-aminoanilide linker.

N. Fujii, H. Ohno, S. Oishi, 2018, Bioorganic & medicinal chemistry letters.

A Cisplatin Derivative that Inhibits Collagen Fibril‐Formation in vitro

T. Koide, N. Fujii, S. Oishi, 2015, Chemical biology & drug design.

CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV.

S. Futaki, M. Matsuoka, Ű. Langel, 2012, Chemistry & biology.

Synthesis and biological evaluation of the [d-MeAla(11)]-epimer of coibamide A.

A. Hau, N. Fujii, H. Ohno, 2015, Bioorganic & medicinal chemistry letters.

Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis

N. Fujii, H. Ohno, S. Oishi, 2013 .

Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C.

N. Fujii, H. Ohno, S. Oishi, 2011, Bioorganic & medicinal chemistry.

Stereoselective divergent synthesis of four diastereomers of pachastrissamine (jaspine B).

N. Fujii, H. Ohno, S. Oishi, 2010, The Journal of organic chemistry.

Isoform-selective regulation of mammalian cryptochromes

T. Hirota, S. Kay, F. Tama, 2020, Nature Chemical Biology.

Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of bromoallenes.

N. Fujii, H. Ohno, S. Oishi, 2009, Organic letters.

Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists.

K. Kitaura, A. Otaka, H. Tamamura, 2006, The Journal of organic chemistry.

Resistance Profiles of Novel Electrostatically Constrained HIV-1 Fusion Inhibitors*

S. Sarafianos, M. Matsuoka, N. Fujii, 2010, The Journal of Biological Chemistry.

Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide.

Shinya Oishi, Mariko Ueno, Kazuya Shimura, 2009, Antiviral research.

Electrostatically constrained alpha-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide.

M. Matsuoka, A. Otaka, Yuji Kobayashi, 2009, The international journal of biochemistry & cell biology.

Palladium-catalysed biscyclisation of allenic bromoalkenes through a zipper-mode cascade.

N. Fujii, H. Ohno, S. Oishi, 2008, Chemical communications.

Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes.

N. Fujii, H. Ohno, T. Noguchi, 2013, Bioorganic & medicinal chemistry letters.

Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds.

Stephen C Peiper, Satoshi Ueda, Shinya Oishi, 2005, Journal of medicinal chemistry.

Construction of the Pyrrolo[2,3- d]carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide.

H. Ohno, S. Oishi, H. Kumagai, 2019, The Journal of organic chemistry.

Optimized method of G-protein-coupled receptor homology modeling: its application to the discovery of novel CXCR7 ligands.

Shinya Oishi, Toshio Furuya, Yasushi Yoshikawa, 2013, Journal of medicinal chemistry.

Thioredoxin-interacting protein suppresses bladder carcinogenesis.

H. Nishiyama, R. Saito, H. Masutani, 2011, Carcinogenesis.

Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats

S. Ohkura, F. Matsuda, N. Inoue, 2020, The Journal of reproduction and development.

Evidence of involvement of neurone‐glia/neurone‐neurone communications via gap junctions in synchronised activity of KNDy neurones

A. Maturana, N. Inoue, M. Sanbo, 2017, Journal of neuroendocrinology.

GPR54 Is a Target for Suppression of Metastasis in Endometrial Cancer

S. Murphy, N. Matsumura, T. Baba, 2011, Molecular Cancer Therapeutics.

Biological Activities of Homologous Loop Regions in the Laminin α Chain G Domains*

A. Utani, H. Kleinman, N. Fujii, 2003, Journal of Biological Chemistry.

Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems.

N. Fujii, H. Ohno, T. Noguchi, 2017, Bioconjugate chemistry.

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

J. Hartley, R. Hopkins, W. Linehan, 2006, Proceedings of the National Academy of Sciences.

Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016

T. Kijima, R. Takahashi, N. Fujii, 2012, FEBS letters.

Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors.

H. Shim, N. Fujii, S. Oishi, 2009, Seminars in cancer biology.

Therapeutic Discovery GPR 54 Is a Target for Suppression of Metastasis in Endometrial Cancer

S. Murphy, N. Matsumura, T. Baba, 2011 .

GnRH suppresses excitability of visual processing neurons in the optic tectum.

S. Oishi, K. Yamaguchi, H. Abe, 2015, Journal of neurophysiology.

Total Synthesis of Dictyodendrins A-F by the Gold-Catalyzed Cascade Cyclization of Conjugated Diyne with Pyrrole.

Y. Miyamoto, M. Oka, H. Ohno, 2020, Chemistry.

A Novel KSP Inhibitor, KPYB10602, Induces Mitotic Arrest and Cell Death in Breast Cancer Cells

K. Tsugawa, Daiki Watanabe, N. Matsumoto, 2016 .

Gold-Catalyzed Cascade Reaction of Skipped Diynes for the Construction of a Cyclohepta[b]pyrrole Scaffold.

H. Ohno, Y. Yoshida, S. Oishi, 2017, Organic letters.

Blockade of CXCL12/CXCR4 Axis Ameliorates Murine Experimental Colitis

T. Chiba, N. Fujii, H. Nakase, 2008, Journal of Pharmacology and Experimental Therapeutics.

The efficacy of a newly developed neurokinin 3 receptor agonist B21-750 on luteinizing hormone secretion in cycling goats

S. Oishi, Tomomi Tanaka, N. Endo, 2019, The Journal of reproduction and development.

Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.

S. Ohkura, T. Yamamura, F. Matsuda, 2014, Journal of medicinal chemistry.

The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases

W. Strittmatter, K. Wada, T. Takeuchi, 2011, Journal of amino acids.

Cyclic peptide analogs of laminin active sequences enhance the biological activity.

M. Nomizu, Y. Kikkawa, S. Oishi, 2009, Advances in experimental medicine and biology.

Synthesis of α,α-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics

J. Deschamps, Dajun Yang, Manchao Zhang, 2004 .

New access to α-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under ‘reduction–oxidative alkylation (R–OA)’ conditions

A. Otaka, H. Tamamura, N. Fujii, 2001 .

Identification of cytochrome P450 isozymes involved in metabolism of the alpha1-adrenoceptor blocker tamsulosin in human liver microsomes.

T. Watanabe, S. Oishi, S. Higuchi, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Bioorganic synthesis of end-capped anti-HIV peptides by simultaneous cyanocysteine-mediated cleavages of recombinant proteins.

M. Matsuoka, N. Fujii, H. Ohno, 2009, Bioorganic & medicinal chemistry.

Development and application of fluorescent SDF-1 derivatives.

G. Tsujimoto, M. Matsuoka, N. Fujii, 2012, Future medicinal chemistry.

Coiled-coil tag--probe system for quick labeling of membrane receptors in living cell.

Yoshiaki Yano, Shinya Oishi, Gozoh Tsujimoto, 2008, ACS chemical biology.

Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides.

A. Utani, H. Kleinman, N. Fujii, 2004, Biochemistry.

SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide

S. Sarafianos, M. Matsuoka, N. Fujii, 2008, Antimicrobial Agents and Chemotherapy.

The effects of 5‐OP‐RU stereochemistry on its stability and MAIT‐MR1 axis

S. Yamasaki, H. Ohno, S. Oishi, 2020, Chembiochem : a European journal of chemical biology.

Fluorescent imaging of high‐grade bladder cancer using a specific antagonist for chemokine receptor CXCR4

H. Nishiyama, R. Saito, O. Ogawa, 2009, International journal of cancer.

Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth.

Susumu Nakata, J. Friedman, T. Kawabe, 2021, Biochemical and biophysical research communications.

Design of Coibamide A Mimetics with Improved Cellular Bioactivity

H. Ohno, S. Oishi, K. McPhail, 2021, ACS medicinal chemistry letters.

A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L-cysteine, a novel Eg5 inhibitor.

Shinya Oishi, Koji Nishizawa, Takahiro Inoue, 2011, Asian journal of andrology.

Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities.

Stephen C Peiper, Satoshi Ueda, Shinya Oishi, 2007, Journal of medicinal chemistry.

Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility.

Shinya Oishi, Shinya Nakamura, Tomoki Takeuchi, 2014, ACS medicinal chemistry letters.

Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.

Shinya Oishi, Hiroyuki Osada, Masato Kaneda, 2013, Bioorganic & medicinal chemistry letters.

Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes.

A. Otaka, H. Tamamura, N. Fujii, 2000, Bioorganic & medicinal chemistry letters.

Efficient synthesis of trifluoromethyl and related trisubstituted alkene dipeptide isosteres by palladium-catalyzed carbonylation of amino acid derived allylic carbonates.

T. Narumi, N. Fujii, H. Ohno, 2008, The Journal of organic chemistry.

Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity.

A. Utani, J. Higo, K. Umezawa, 2007, Biochemistry.

A novel one-pot reaction involving organocopper-mediated reduction/transmetalation/asymmetric alkylation, leading to the diastereoselective synthesis of functionalized (Z)-fluoroalkene dipeptide isosteres.

T. Narumi, A. Otaka, N. Fujii, 2006, Chemical communications.

A Novel One‐Pot Reaction Involving Organocopper‐Mediated Reduction/Transmetalation/Asymmetric Alkylation, Leading to the Diastereoselective Synthesis of Functionalized (Z)‐Fluoroalkene Dipeptide Isosteres.

T. Narumi, A. Otaka, N. Fujii, 2007 .

Total Synthesis of (+)-Polyoxamic Acid via Visible-Light-Mediated Photocatalytic β-Scission and 1,5-Hydrogen Atom Transfer of Glucose Derivative.

H. Ohno, S. Oishi, S. Inuki, 2020, The Journal of organic chemistry.

Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists.

J. Broach, N. Fujii, S. Oishi, 2009, Methods in enzymology.

Development of novel NK3 receptor antagonists with reduced environmental impact.

S. Ohkura, F. Matsuda, N. Fujii, 2016, Bioorganic & medicinal chemistry.

Synthesis of the Src SH2 domain and its application in bioassays for mirror-image screening

N. Fujii, H. Ohno, T. Noguchi, 2017 .

Reactive Intermediate Chemistry Edited by R. A. Moss (Rutgers University), M. S. Platz (Ohio State University), and M. Jones, Jr. (Princeton University). Wiley-Interscience, Hoboken, NJ. 2004. viii + 1072 pp. 16 × 24 cm. $95.95. ISBN 0-471-23324-2.

S. Oishi, 2004 .

Investigation of the inhibitory mechanism of apomorphine against MDM2-p53 interaction.

N. Fujii, H. Ohno, T. Noguchi, 2017, Bioorganic & medicinal chemistry letters.

Examination of acylated 4-aminopiperidine-4-carboxylic acid residues in the phosphotyrosyl+1 position of Grb2 SH2 domain-binding tripeptides.

R. Fisher, T. Burke, W. J. Choi, 2007, Journal of Medicinal Chemistry.

Easy-to-Attach/Detach Solubilizing-Tag-Aided Chemical Synthesis of an Aggregative Capsid Protein.

Taku Yoshiya, S. Oishi, H. Nishio, 2018, Angewandte Chemie.

Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors

S. Matsushita, M. Matsuoka, N. Fujii, 2016, Retrovirology.

Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold.

M. Matsuoka, N. Fujii, H. Ohno, 2015, Bioorganic & medicinal chemistry.

Prognostic value of metastin expression in human pancreatic cancer

T. Masui, M. Koizumi, R. Doi, 2009, Journal of experimental & clinical cancer research : CR.

Screening of a virtual mirror-image library of natural products.

N. Fujii, H. Ohno, T. Noguchi, 2016, Chemical communications.

X-ray crystallographic study of an HIV-1 fusion inhibitor with the gp41 S138A substitution.

K. Kitaura, M. Matsuoka, T. Nakatsu, 2009, Journal of molecular biology.

Design of Peptide-based Inhibitors for Human Immunodeficiency Virus Type 1 Strains Resistant to T-20*

K. Kitaura, S. Sarafianos, M. Matsuoka, 2009, Journal of Biological Chemistry.

Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain.

N. Fujii, M. Nomizu, Y. Mizuno, 2005, Biochemistry.

Facile access to (Z)-alkene-containing diketopiperazine mimetics utilizing organocopper-mediated anti-SN2′ reactions

A. Otaka, H. Tamamura, N. Fujii, 2005 .

Structure–activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists

S. Ohkura, T. Yamamura, F. Matsuda, 2015 .

Scaffold hopping of fused piperidine-type NK3 receptor antagonists to reduce environmental impact.

H. Ohno, S. Oishi, S. Inuki, 2019, Bioorganic & medicinal chemistry.

Title Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C

N. Fujii, H. Ohno, S. Oishi, 2019 .

The Synthesis of Alkaloids Using Transition-Metal-Catalyzed Intramolecular Amination Reactions

N. Fujii, H. Ohno, S. Oishi, 2013, Synlett.

Bioorganic synthesis of a recombinant HIV-1 fusion inhibitor, SC35EK, with an N-terminal pyroglutamate capping group.

M. Matsuoka, N. Fujii, H. Ohno, 2009, Bioorganic & medicinal chemistry.

Cu(II)-Mediated Oxidative Intermolecular ortho C—H Functionalization Using Tetrahydropyrimidine as the Directing Group.

N. Fujii, H. Ohno, S. Oishi, 2009 .

Isoform selective regulation of mammalian Cryptochromes

T. Hirota, S. Kay, F. Tama, 2020 .

GXXXG-Mediated Parallel and Antiparallel Dimerization of Transmembrane Helices and Its Inhibition by Cholesterol: Single-Pair FRET and 2D IR Studies.

M. Zanni, N. Fujii, K. Matsuzaki, 2017, Angewandte Chemie.

Isolation, structure elucidation, and total synthesis of tryptopeptins A and B, new TGF-β signaling modulators from Streptomyces sp.

N. Fujii, S. Oishi, Y. Tsunematsu, 2015, Organic Letters.

Isolation, Structure Elucidation, and Total Synthesis of Tryptopeptins A and B, New TGF‐β Signaling Modulators from Streptomyces sp.

N. Fujii, S. Oishi, Y. Tsunematsu, 2015 .

Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4).

N. Fujii, S. Oishi, 2012, Organic & biomolecular chemistry.

Molecular modeling study of cyclic pentapeptide CXCR4 antagonists: new insight into CXCR4-FC131 interactions.

N. Fujii, T. Furuya, S. Oishi, 2012, Bioorganic & medicinal chemistry letters.

Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors.

H. Shim, N. Fujii, S. Oishi, 2009, Seminars in cancer biology.

Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic

T. Narumi, N. Fujii, H. Ohno, 2008 .

Development of novel CXC chemokine receptor 7 (CXCR7) ligands: selectivity switch from CXCR4 antagonists with a cyclic pentapeptide scaffold.

N. Heveker, N. Fujii, H. Ohno, 2015, Journal of medicinal chemistry.

Mode of binding of the cyclic agonist peptide TC14012 to CXCR7: identification of receptor and compound determinants.

N. Heveker, N. Fujii, S. Oishi, 2015, Biochemistry.

The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7

D. Sinnett, R. Leduc, N. Heveker, 2010, The Journal of Biological Chemistry.

Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations.

K. Kitaura, T. Narumi, A. Otaka, 2006, The Journal of organic chemistry.

Construction of a Bicyclo[2.2.2]octene Skeleton via a Visible-Light-Mediated Radical Cascade Reaction of Amino Acid Derivatives with N-(2-Phenyl)benzoyl Groups.

S. Oishi, S. Inuki, Norihito Arichi, 2023, Organic letters.

Synthesis of IB-01212 by multiple N-methylations of peptide bonds.

N. Fujii, H. Ohno, S. Oishi, 2014, Bioorganic & medicinal chemistry.

Construction of Quaternary Carbon Stereocenter of α-Tertiary Amine through Remote C-H Functionalization of Tris Derivatives: Enantioselective Total Synthesis of Myriocin

S. Oishi, S. Inuki, Hiroaki Ohno, 2020 .

Novel 3,4,7-Substituted Benzofuran Derivatives Having Binding Affinity to κ-Opioid Receptor.

N. Fujii, H. Ohno, S. Oishi, 2016, Chemical & pharmaceutical bulletin.

HIV-1 Resistance Mechanism to an Electrostatically Constrained Peptide Fusion Inhibitor That Is Active against T-20-Resistant Strains

S. Sarafianos, M. Matsuoka, N. Fujii, 2013, Antimicrobial Agents and Chemotherapy.

Identification of minimal sequence for HIV-1 fusion inhibitors.

M. Matsuoka, A. Otaka, N. Fujii, 2008, Bioorganic & Medicinal Chemistry.

GPR54 Is a Target for Suppression of Metastasis in Endometrial Cancer

S. Murphy, N. Matsumura, T. Baba, 2011, Molecular Cancer Therapeutics.

A Novel Oxazolidine Linker for the Synthesis of Peptide Aldehydes

N. Fujii, H. Ohno, S. Oishi, 2007, International Journal of Peptide Research and Therapeutics.

Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound

T. Hirota, S. Kay, F. Tama, 2020 .

Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction of indoloquinolines.

N. Fujii, H. Ohno, S. Oishi, 2014, Organic letters.

Ring-construction/stereoselective functionalization cascade: total synthesis of pachastrissamine (jaspine B) through palladium-catalyzed bis-cyclization of propargyl chlorides and carbonates.

N. Fujii, H. Ohno, S. Oishi, 2010, The Journal of organic chemistry.

Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes.

N. Fujii, H. Ohno, S. Oishi, 2012, The Journal of organic chemistry.

Total Synthesis of (+)-Conolidine by the Gold(I)-Catalyzed Cascade Cyclization of a Conjugated Enyne.

N. Fujii, H. Ohno, Y. Yoshida, 2016, The Journal of organic chemistry.

Efficient synthesis of aminomethylated pyrroloindoles and dipyrrolopyridines via controlled copper-catalyzed domino multicomponent coupling and bis-cyclization.

N. Fujii, H. Ohno, S. Oishi, 2009, The Journal of organic chemistry.

Synthesis of fused and linked bicyclic nitrogen heterocycles by palladium-catalyzed domino cyclization of propargyl bromides.

N. Fujii, H. Ohno, S. Oishi, 2010, Chemistry.

Direct synthesis of aryl-annulated [c]carbazoles by gold(i)-catalysed cascade reaction of azide-diynes and arenes

S. Oishi, S. Inuki, Junpei Matsuoka, 2018, Chemical science.

Structure − Activity Relationship Study on Odoamide: Insights into the Bioactivities of Aurilide-Family Hybrid Peptide − Polyketides

N. Fujii, H. Ohno, S. Oishi, 2018 .

Development of a novel fusion inhibitor against T-20-resistant HIV-1.

M. Matsuoka, A. Otaka, N. Fujii, 2009, Advances in experimental medicine and biology.

Kisspeptin receptor agonist (FTM080) increased plasma concentrations of luteinizing hormone in anestrous ewes

L. Amelse, N. Fujii, S. Oishi, 2015, PeerJ.

Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.

Marc C Nicklaus, Shinya Oishi, Robert J Fisher, 2005, Journal of medicinal chemistry.

Diversity-oriented synthesis of pyrazolo[4,3-b]indoles by gold-catalysed three-component annulation: application to the development of a new class of CK2 inhibitors.

G. Tsujimoto, N. Fujii, H. Ohno, 2013, Organic & biomolecular chemistry.

Antiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein.

H. Tsujimoto, N. Fujii, S. Oishi, 2009, Veterinary microbiology.