P. C. Ruenitz

发表

Large Class Student-Centered Pharmaceutical Science Instruction: Is Classroom Attendance Necessary? Does Performance Affect Course Assessment?

P. C. Ruenitz, 2000 .

Female Sex Hormones, Contraceptives, And Fertility Drugs

P. C. Ruenitz, 2003 .

Promoting In-Class Student Involvement in Medicinal Chemistry

P. C. Ruenitz, 1997, American Journal of Pharmaceutical Education.

Mechanisms of growth inhibition by nonsteroidal antioestrogens in human breast cancer cells.

R. Sutherland, C. K. Watts, P. C. Ruenitz, 1987, Journal of steroid biochemistry.

Identification of new triarylethylene oxyalkanoic acid analogues as bone selective estrogen mimetics.

P. C. Ruenitz, F. D. Boudinot, V. N. Rubin, 2001, Bioorganic & medicinal chemistry.

Interaction of tricyclic antipsychotic and antidepressant drugs with 1-anilino-8-naphthalenesulfonic acid.

P. C. Ruenitz, H. Jun, 1978, Journal of pharmaceutical sciences.

Characterization of selective estrogen receptor modulator (SERM) activity in two triarylethylene oxybutyric acids.

P. C. Ruenitz, T. Wiese, F. D. Boudinot, 2002, Biochemical pharmacology.

Inhibition of rabbit liver microsomal oxidative metabolism and substrate binding by tamoxifen and the geometric isomers of clomiphene.

P. C. Ruenitz, M. M. Toledo, 1980, Biochemical pharmacology.

Cytochrome P-450-mediated N-dechloroethylation of cyclophosphamide and ifosfamide in the rat.

P. C. Ruenitz, J. Ruzicka, 1992, Drug metabolism and disposition: the biological fate of chemicals.

Derivatization-liquid chromatographic assay of chloroacetaldehyde in biological samples.

P. C. Ruenitz, J. Ruzicka, 1990, Journal of chromatography.

Estrogenic tamoxifen derivatives: Categorization of intrinsic estrogenicity in MCF-7 cells

P. C. Ruenitz, S. A. Moore, K. S. Kraft, 1997, The Journal of Steroid Biochemistry and Molecular Biology.

Resolution, absolute configuration, and antiarrhythmic properties of the enantiomers of disopyramide, 4-(diisopropylamino)-2-(2-pyridyl)-2-phenylbutyramide.

W. L. Nelson, T. Burke, G. Hite, 1980, Journal of medicinal chemistry.

Estrogenic triarylethylene acetic acids: effect of structural variation on estrogen receptor affinity and estrogenic potency and efficacy in MCF-7 cells.

P. C. Ruenitz, S. A. Moore, C. Bourne, 1996, Journal of medicinal chemistry.

Some chemical and biochemical aspects of liver microsomal metabolism of tamoxifen.

C. Pape, P. C. Ruenitz, J. Bagley, 1984, Drug metabolism and disposition: the biological fate of chemicals.

Estrogenic and antiestrogenic activity of monophenolic analogues of tamoxifen, (Z)-2-[p-(1,2-diphenyl-1-butenyl)phenoxy]-N, N-dimethylethylamine.

P. C. Ruenitz, J. Bagley, C. M. Mokler, 1982, Journal of medicinal chemistry.

Specific bone-protective effects of metabolites/derivatives of tamoxifen and clomiphene in ovariectomized rats.

P. C. Ruenitz, T. Wronski, Y. Shen, 1998, Bone.

Acidic metabolites of tamoxifen. Aspects of formation and fate in the female rat.

P. C. Ruenitz, X. Bai, 1995, Drug metabolism and disposition: the biological fate of chemicals.

Characterization of MCF 7 breast cancer cell growth inhibition by the antiestrogen nitromifene (CI 628) and selected metabolites.

P. C. Ruenitz, V. Srivatsan, C. Thompson, 1989, Journal of steroid biochemistry.

Metabolism of clomiphene in the rat. Estrogen receptor affinity and antiestrogenic activity of clomiphene metabolites.

P. C. Ruenitz, J. Bagley, C. M. Mokler, 1983, Biochemical pharmacology.

Drugs for Osteoporosis Prevention: Mechanisms of Bone Maintenance

P. C. Ruenitz, 1995, Current Medicinal Chemistry.

Phenolic metabolites of clomiphene: [(E,Z)-2-[4-(1,2-diphenyl-2-chlorovinyl)phenoxy]ethyl]diethylamine. Preparation, electrophilicity, and effects in MCF 7 breast cancer cells.

P. C. Ruenitz, R. Arrendale, W. Schmidt, 1989, Journal of medicinal chemistry.

Synthesis, conformational analysis, and antiarrhythmic properties of 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonan-9-one, 7-benzyl-3-thia-7-azabicyclo[3.3.1]nonane hydroperchlorate, and 7-benzyl-9-phenyl-3-thia-7-azabicyclo[3.3.1]nonan-9-ol hydroperchlorate and derivatives: single-crystal X-ray diffracti

E. M. Holt, R. Lazzara, D. van der Helm, 1984, Journal of medicinal chemistry.

Conformational studies of some 2-exo-alkyl-3-benzyl-3-azabicyclo[3.3.1]nonanes

P. C. Ruenitz, 1978 .

Analogues of sparteine. 3. Synthesis and conformational studies of some 2,3-substituted 7-methyl-3,7-diazabicyclo[3.3.1]nonanes.

P. C. Ruenitz, E. Smissman, 1977, The Journal of organic chemistry.

7-Aza analogs of the analgetic agent azabicyclane. Synthesis and pharmacologic analysis.

P. C. Ruenitz, E E Smissman, P C Ruenitz, 1976, Journal of medicinal chemistry.

Mechanistic aspects of oxidation of N‐substituted 5H‐dibenz[c,e]azepines by aldehyde oxidase

P. C. Ruenitz, H. Thomas, 1984 .

Comparative fates of clomiphene and tamoxifen in the immature female rat.

P. C. Ruenitz, J. Bagley, 1985, Drug metabolism and disposition: the biological fate of chemicals.

Biotransformation of the antiestrogen clomiphene to chemically reactive metabolites in the immature female rat.

P. C. Ruenitz, R. Arrendale, N. Nanavati, 1987, Cancer research.

Skin reactions of rats to levamisole and D-penicillamine.

G. B. West, P. C. Ruenitz, J. Sorenson, 1980, International Archives of Allergy and Applied Immunology.

Definition of two distinct mechanisms of action of antiestrogens on human breast cancer cell proliferation using hydroxytriphenylethylenes with high affinity for the estrogen receptor.

R. Sutherland, C. K. Watts, P. C. Ruenitz, 1986, Biochemical and biophysical research communications.

Structural characterization and biological effects of photocyclized products of tamoxifen irradiation.

P. C. Ruenitz, S. Wilson, Susanne Wilson, 1993, Journal of pharmaceutical sciences.

Metabolism of nitromiphene (CI 628) in the immature female rat: role of gastrointestinal microflora in the biotransformation of a triarylethylene antiestrogen.

P. C. Ruenitz, J. Bagley, 1986, Cancer research.

Substituted-vinyl hydroxytriarylethylenes, 1-[4-[2-(diethylamino) ethoxy]phenyl]-1-(4-hydroxyphenyl)-2-phenylethylenes: synthesis and effects on MCF 7 breast cancer cell proliferation.

R. Sutherland, C. K. Watts, P. C. Ruenitz, 1986, Journal of Medicinal Chemistry.

Substituted-Vinyl Hydroxytriarylethylenes, 1-(4-(2-(Diethylamino)ethoxy)phenyl)-1-(4-hydroxyphenyl)-2-phenylethylenes: Synthesis and Effects on MCF 7 Breast Cancer Cell Proliferation.

R. Sutherland, C. K. Watts, P. C. Ruenitz, 1987 .

Estrogen receptor affinity and effects on MCF-7 cell growth of triarylethylene carboxylic acids related to tamoxifen

P. C. Ruenitz, J. Ruzicka, Susanne Wilson, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Identification and distribution in the rat of acidic metabolites of tamoxifen.

P. C. Ruenitz, N. Nanavati, 1990, Drug metabolism and disposition: the biological fate of chemicals.

Formation of benzophenone and α,α-diarylacetophenone metabolites of the antiestrogen nitromiphene (CI628) in the presence of rat cecal contents

P. C. Ruenitz, J. Bagley, 1983 .

Primary deuterium isotope effect in the oxidation of an iminium ion by aldehyde oxidase.

P. C. Ruenitz, H. Thomas, 1985, Archives of biochemistry and biophysics.

Structural requirements for the pharmacological activity of nonsteroidal antiestrogens in vitro.

V. Jordan, P. C. Ruenitz, R. Koch, 1984, Molecular pharmacology.

Synthesis and estrogen receptor selectivity of 1,1-bis(4-hydroxyphenyl)-2-(p-halophenyl)ethylenes.

P. C. Ruenitz, N. Nanavati, J. Bagley, 1988, Journal of medicinal chemistry.

Chemical and biochemical characteristics of O-demethylation of chlorotrianisene in the rat.

P. C. Ruenitz, M. M. Toledo, 1981, Biochemical pharmacology.

The preparation of carbon‐14 labelled 1‐[4‐(2‐diethylamino‐ethoxy) phenyl]‐1, 2‐diphenyl‐2‐chloroethene (clomiphene) and 1‐[4‐(2‐(N‐pyrrolidinyl) ethoxy) phenyl]‐2‐(4‐methoxyphenyl)‐2‐nitro‐2‐phenylethene (CI‐628, nitromiphene)

P. C. Ruenitz, J. Bagley, 1983 .

Antiarrhythmic activity of some N-alkylbispidinebenzamides.

P. C. Ruenitz, C. M. Mokler, 1979, Journal of medicinal chemistry.

SYNTHESIS, CONFORMATIONAL ANALYSIS, AND ANTIARRHYTHMIC PROPERTIES OF 7‐BENZYL‐3‐THIA‐7‐AZABICYCLO(3.3.1)NONAN‐9‐ONE, 7‐BENZYL‐3‐THIA‐7‐AZABICYCLO(3.3.1)NONANE HYDROPERCHLORATE, AND 7‐BENZYL‐9‐PHENYL‐3‐THIA‐7‐AZABICYCLO(3.3.1)NONAN‐9‐OL HYDROPERCHLORATE AND DERIVATIVES. SINGLE‐CRYSTAL X‐RAY DIFFRACTI

E. M. Holt, R. Lazzara, B. Scherlag, 1984 .

Analogues of sparteine. 5. Antiarrhythmic activity of selected N,N'-disubstituted bispidines.

P. C. Ruenitz, C. M. Mokler, 1977, Journal of Medicinal Chemistry.

ANTIARRHYTHMIC ACTIVITY OF SOME N-ALKYLBISPIDINEBENZAMIDES

P. C. Ruenitz, C. M. Mokler, 1980 .

ANALOGS OF SPARTEINE. 5. ANTIARRHYTHMIC ACTIVITY OF SELECTED N,N′-DISUBSTITUTED BISPIDINES

P. C. Ruenitz, C. M. Mokler, 1978 .

Analogues of sparteine. II. Synthesis of N-monoalkylbispidines and N,N'-dialkylbispidines.

P. C. Ruenitz, E. Smissman, 1976, The Journal of organic chemistry.

Analogs of sparteine. I. A reexamination of the reaction of n-methyl-4-piperidone with formaldehyde and methylamine. A revised synthesis of n,n'-dimethylbispidinone.

P. C. Ruenitz, E. Smissman, J. A. Weis, 1975, The Journal of organic chemistry.

Analogs of sparteine. IV. Mass spectral features of a series of N, N′-disubstituted bispidines

P. C. Ruenitz, E. Smissman, D. Wright, 1977 .

ANALOGS OF SPARTEINE PART 1, A REECAMINATION OF THE REACTION OF N-METHYL-4-PIPERIDONE WITH FORMALDEHYDE AND METHYLAMINE, A REVISED SYNTHESIS OF N,N′-DIMETHYLBISPIDINONE

P. C. Ruenitz, E. Smissman, J. A. Weis, 1975 .

Use of the mannich reaction in the synthesis of bispidine

P. C. Ruenitz, E. Smissman, 1976 .

ANALOGUES OF SPARTEINE. II. SYNTHESIS OF N-MONOALKYLBISPIDINES AND N,N′-DIALKYLBISPIDINES

P. C. Ruenitz, E. Smissman, 1976 .

Reduction of iminium ethers with sodium boro[3H] hydride. Preparation of tritium labelled clomiphene and nitromiphene (CI 628)†

P. C. Ruenitz, J. Bagley, 1984 .

Antiestrogens. 3. Estrogen receptor affinities and antiproliferative effects in MCF-7 cells of phenolic analogues of trioxifene, [3,4-dihydro-2-(4- methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]- phenyl]methanone.

P. C. Ruenitz, L. Blaszczak, V. Srivatsan, 1992, Journal of medicinal chemistry.