C. Exley

C. Exley, D. Vassallo, M. Salaices, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Granulomas Following Subcutaneous Injection With Aluminum Adjuvant-Containing Products in Sheep

I. de Blas, L. Luján, C. Exley, 2018, Veterinary pathology.

Unequivocal identification of intracellular aluminium adjuvant in a monocytic THP-1 cell line

P. Siesjö, C. Exley, A. Darabi, 2014, Scientific Reports.

Aluminum exposure at human dietary levels promotes vascular dysfunction and increases blood pressure in rats: A concerted action of NAD(P)H oxidase and COX-2.

C. Exley, D. Vassallo, M. Salaices, 2017, Toxicology.

Redox cycling of iron by Abeta42.

J. Dobson, C. Exley, A. Khan, 2006, Free radical biology & medicine.

Aluminium in Brain Tissue in Epilepsy: A Case Report from Camelford

C. Exley, M. Mold, Jason Cottle, 2019, International journal of environmental research and public health.

Identification of the aquaporin gene family in Cannabis sativa and evidence for the accumulation of silicon in its tissues.

R. Deshmukh, H. Sonah, K. Siddiqui, 2019, Plant science : an international journal of experimental plant biology.

Visualising Silicon in Plants: Histochemistry, Silica Sculptures and Elemental Imaging

C. Exley, N. Valle, J. Hausman, 2020, Cells.

Callose-associated silica deposition in Arabidopsis.

C. Exley, Thibault Brugiére, 2017, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Silicic acid: The omniscient molecule.

X. López, C. Exley, G. Guerriero, 2019, The Science of the total environment.

Urinary Excretion of Aluminium and Silicon in Secondary Progressive Multiple Sclerosis

C. Linhart, C. Exley, C. Hawkins, 2017, EBioMedicine.

Reflections upon and recent insight into the mechanism of formation of hydroxyaluminosilicates and the therapeutic potential of silicic acid

C. Exley, 2012 .

A possible mechanism of biological silicification in plants

C. Exley, 2015, Front. Plant Sci..

Biological availability of aluminum in commercial ATP

J. Birchall, C. Exley, 1996 .

Aluminum and Alzheimer's disease.

C. Exley, 2001, Journal of Alzheimer's disease : JAD.

Avoidance of aluminum by rainbow trout

C. Exley, 2000 .

Aluminium in human sweat.

C. Exley, Jodie Nadal, C. Minshall, 2014, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Aluminium in Brain Tissue in Multiple Sclerosis

C. Linhart, A. King, C. Exley, 2018, International Journal of Environmental Research and Public Health.

A mechanism of hydroxyaluminosilicate formation

J. Birchall, C. Exley, 1993 .

Hydroxyaluminosilicate formation in solutions of low total aluminum concentration

J. Birchall, C. Exley, 1992 .

Thermal analyses of aluminium hydroxide and hydroxyaluminosilicates

C. Exley, S. Strekopytov, 2006 .

Aluminium in human breast tissue.

C. Exley, A. Polwart, P. Darbre, 2007, Journal of inorganic biochemistry.

Bumblebee Pupae Contain High Levels of Aluminium

D. Goulson, C. Exley, E. Rotheray, 2015, PloS one.

The aluminium content of breast tissue taken from women with breast cancer.

C. Exley, A. Polwart, P. Darbre, 2013, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Erratum to “The pro-oxidant activity of aluminum” [Free Radic. Biol. Med. 36 (2004) 380–387]

C. Exley, 2005 .

Aluminium-induced phospholipid signal transduction pathway in Coffea arabica suspension cells and its amelioration by silicic acid.

C. Exley, M. Martínez-Estévez, J. Muñoz-Sánchez, 2007, Journal of inorganic biochemistry.

Aluminium in brain tissue in familial Alzheimer's disease.

C. Troakes, A. King, C. Exley, 2017, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome.

Christopher Exley, F. Authier, C. Exley, 2009, Medical hypotheses.

Aluminum and Neurofibrillary Tangle Co-Localization in Familial Alzheimer’s Disease and Related Neurological Disorders

C. Exley, M. Mold, Benjamin Morris, 2020, Journal of Alzheimer's disease : JAD.

The measurement and full statistical analysis including Bayesian methods of the aluminium content of infant vaccines.

C. Linhart, C. Exley, Emma Shardlow, 2021, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Highly delayed systemic translocation of aluminum-based adjuvant in CD1 mice following intramuscular injections.

B. Giros, E. Tzavara, P. Curmi, 2015, Journal of inorganic biochemistry.

The Body Is an Effective Barrier to Exposure to Aluminium ?

C. Exley, 2009 .

Organosilicon therapy in Alzheimer's disease?

C. Exley, 2007, Journal of Alzheimer's disease : JAD.

The Solubility of Hydroxyaluminosilicates and the Biological Availability of Aluminium

C. Exley, 2007 .

Aluminium in human brain tissue: how much is too much?

C. Exley, M. Mold, Matthew J. Mold, 2019, JBIC Journal of Biological Inorganic Chemistry.

Aluminum toxicokinetics.

E. Jeffery, C. Exley, R. Yokel, 1996, Journal of toxicology and environmental health.

Acid Rain: Implications For The Farming of Salmonids

C. Exley, M. Phillips, 1988 .

Silicic acid (Si(OH)(4)) is a significant influence upon the atomic absorption signal of aluminium measured by graphite furnace atomic absorption spectrometry (GFAAS).

C. Exley, C. Schneider, 2001, Journal of inorganic biochemistry.

Computational approach to the blood–aluminum problem?†

G. Rugg, C. Exley, James Beardmore, 2007 .

C. Exley, Shelle-Ann M Burrell, 2010 .

The binding, transport and fate of aluminium in biological cells.

C. Exley, M. Mold, Matthew J. Mold, 2015, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Elucidating Aluminiums Exposome

C. Exley, 2012 .

Darwin, natural selection and the biological essentiality of aluminium and silicon.

C. Exley, 2009, Trends in biochemical sciences.

Aluminium co-localises with Biondi ring tangles in Parkinson’s disease and epilepsy

C. Exley, M. Mold, Matthew J. Mold, 2022, Scientific Reports.

Aluminum and Tau in Neurofibrillary Tangles in Familial Alzheimer’s Disease

C. Exley, M. Mold, Benjamin Morris, 2021, Journal of Alzheimer's disease reports.

Pro-oxidant activity of aluminum: promoting the Fenton reaction by reducing Fe(III) to Fe(II).

X. López, C. Exley, F. Ruipérez, 2012, Journal of inorganic biochemistry.

Comment on "the biological behaviour and bioavailability of aluminium in man" by N. D. Priest, JEM, 2004, 6, 375.

Christopher Exley, C. Exley, 2005, Journal of environmental monitoring : JEM.

Aluminium-based adjuvants should not be used as placebos in clinical trials.

C. Exley, 2011, Vaccine.

Does either the gastrointestinal peptide PYY or the neuropeptide NPY bind aluminium?

A. Ashcroft, C. Exley, J. Croom, 2003, Journal of inorganic biochemistry.

Aluminium: a natural adjuvant in Leishmania transmission via sand flies?

C. Exley, R. Ward, K. Walker, 2008, Transactions of the Royal Society of Tropical Medicine and Hygiene.

A mechanism for acute aluminium toxicity in fish.

J. Birchall, C. Exley, J. Chappell, 1991, Journal of theoretical biology.

Further insight into the mechanism of formation of hydroxyaluminosilicates

C. Exley, S. Strekopytov, E. Jarry, 2006 .

The precipitation of mucin by aluminium.

C. Exley, 1998, Journal of inorganic biochemistry.

Kinetic constraints in acute aluminium toxicity in the rainbow trout (Oncorhynchus mykiss).

J. Birchall, C. Exley, A. Wicks, 1996, Journal of theoretical biology.

Use of Underarm Cosmetic Products in Relation to Risk of Breast Cancer: A Case-Control Study

H. Lindner, H. Ulmer, S. Taucher, 2017, EBioMedicine.

Aluminum: a potential pro-oxidant in sunscreens/sunblocks?

C. Exley, S. Nicholson, 2007, Free radical biology & medicine.

Elevated brain aluminium and early onset Alzheimer’s disease in an individual occupationally exposed to aluminium: a case report

C. Exley, Thomas Vickers, 2014, Journal of Medical Case Reports.

Aluminum in antiperspirants: more than just skin deep.

C. Exley, 2004, The American journal of medicine.

Silicon-rich mineral water as a non-invasive test of the 'aluminum hypothesis' in Alzheimer's disease.

Christopher Exley, Anthony Polwart, Peter Crome, 2012, Journal of Alzheimer's disease : JAD.

The immunobiology of aluminium adjuvants: how do they really work?

Christopher Exley, P. Siesjö, C. Exley, 2010, Trends in immunology.

The aluminium-amyloid cascade hypothesis and Alzheimer's disease.

C. Exley, 2005, Sub-cellular biochemistry.

Elevated urinary excretion of aluminium and iron in multiple sclerosis

C. Exley, A. Polwart, C. Hawkins, 2006, Multiple sclerosis.

Chapter 22 – The Association of Aluminium and β Amyloid in Alzheimer’s Disease

C. Exley, O. Korchazhkina, 2001 .

An interaction of β‐amyloid with aluminium in vitro

N. C. Price, J. Birchall, C. Exley, 1993 .

Non-invasive therapy to reduce the body burden of aluminium in Alzheimer's disease.

P. Crome, C. Exley, A. Polwart, 2006, Journal of Alzheimer's disease : JAD.

Silicon and bone.

C. Exley, 2009, Bone.

CLINICAL STUDY: Elevated urinary aluminium in current and past users of illicit heroin

U. Ahmed, C. Exley, A. Polwart, 2007, Addiction biology.

A vexing Commentary on the important issue of aluminium and Alzheimer' disease.

C. Exley, 2006, Journal of Alzheimer's disease : JAD.

Aluminium and Alzheimer's Disease: The Science that Describes the Link

C. Exley, 2001 .

Aluminium and Alzheimer's disease.

J. Birchall, C. Exley, 1993, Age and ageing.

Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK

M. Esiri, C. Exley, 2006, Journal of Neurology, Neurosurgery & Psychiatry.

Preface: Why is Research into Aluminium and Life Important?

C. Exley, 2001 .

Silicon in natural waters and the bioavailability of aluminium

J. Birchall, C. Exley, J. Chappell, 1989 .

Aluminium in human brain tissue from donors without neurodegenerative disease: A comparison with Alzheimer’s disease, multiple sclerosis and autism

C. Exley, Elizabeth Clarkson, 2020, Scientific Reports.

Aluminium and iron, but neither copper nor zinc, are key to the precipitation of beta-sheets of Abeta_{42} in senile plaque cores in Alzheimer's disease.

C. Exley, 2006, Journal of Alzheimer's disease : JAD.

Aluminium in the brain and heart of the rainbow trout

C. Exley, 1996 .

Polynuclear aluminium and acute aluminium toxicity in the fish.

J. Birchall, C. Exley, A. Wicks, 1994, Journal of theoretical biology.

The solubility of an hydroxyaluminosilicate

F. J. Doucet, C. Exley, S. Strekopytov, 2004 .

Aluminum-induced alterations of purinergic signalling in embryonic neural progenitor cells.

H. Ulrich, M. Pillat, V. Morsch, 2020, Chemosphere.

What is the mechanism of formation of hydroxyaluminosilicates?

X. López, C. Exley, James Beardmore, 2016, Scientific Reports.

The formation, precipitation and structural characterisation of hydroxyaluminosilicates formed in the presence of fluoride and phosphate

C. Exley, S. Strekopytov, 2005 .

Pro-oxidant activity of aluminum: stabilization of the aluminum superoxide radical ion.

X. López, C. Exley, F. Ruipérez, 2011, The journal of physical chemistry. A.

Spherulites in human brain tissue are composed of β sheets of amyloid and resemble senile plaques.

C. Exley, E. House, Krista L. Jones, 2011, Journal of Alzheimer's disease : JAD.

Aluminum in tobacco and cannabis and smoking-related disease.

C. Exley, R. Bloor, A. Begum, 2006, The American journal of medicine.

Aluminum affects neural phenotype determination of embryonic neural progenitor cells

H. Ulrich, M. Pillat, V. Morsch, 2019, Archives of Toxicology.

Human pro-islet amyloid polypeptide (ProIAPP(1-48)) forms amyloid fibrils and amyloid spherulites in vitro.

P. Fraser, C. Exley, E. House, 2010, Journal of inorganic biochemistry.

Measurement by reversed-phase high-performance liquid chromatography of malondialdehyde in normal human urine following derivatisation with 2,4-dinitrophenylhydrazine.

C. Exley, O. Korchazhkina, Stephen Andrew Spencer, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Evidence of redox-active iron formation following aggregation of ferrihydrite and the Alzheimer's disease peptide β-amyloid.

C. Jenkins, J. Dobson, J. Collingwood, 2014, Inorganic chemistry.

Dietary Egg White Hydrolysate Prevents Male Reproductive Dysfunction after Long-Term Exposure to Aluminum in Rats

C. Exley, D. Vassallo, F. Peçanha, 2022, Metabolites.

Egg White Hydrolysate as a functional food ingredient to prevent cognitive dysfunction in rats following long-term exposure to aluminum

C. Exley, P. Mello-Carpes, D. Vassallo, 2019, Scientific Reports.

Camelford, Cornwall, UK with increased brain aluminium in a resident of Severe cerebral congophilic angiopathy coincident

M. Esiri, C. Exley, 2006 .

Aluminium, tau and Alzheimer's disease.

C. Exley, 2007, Journal of Alzheimer's disease : JAD.

The degradation of Abeta(25-35) by the serine protease plasmin is inhibited by aluminium.

A. Ashcroft, C. Exley, T. Kiss, 2002, Journal of Alzheimer's disease : JAD.

Significant omissions of copper-amyloid research in ‘Metal Ions in Neurodegenerative Diseases’ special issue (CCR 256 (19,20) 2012)

C. Exley, 2012 .

Spherulites of Aβ42 in vitro and in Alzheimer’s disease

A. Donald, J. Collingwood, C. Exley, 2009 .

Spherulite so fAmyloid-β 42 I nVitr oan din Alzheimer's Disease

A. Donald, J. Collingwood, C. Exley, 2010 .

Spherulites of amyloid-beta42 in vitro and in Alzheimer's disease.

A. Donald, J. Collingwood, C. Exley, 2010, Journal of Alzheimer's disease : JAD.

Intracellular tracing of amyloid vaccines through direct fluorescent labelling

C. Exley, Emma Shardlow, M. Mold, 2018, Scientific Reports.

Peer review versus editorial review and their role in innovative science

Carlos A. Vega, T. Baumgartner, J. Sacher, 2012, Theoretical medicine and bioethics.

Aluminium and iron, but neither copper nor zinc, are key to the precipitation of beta-sheets of Abeta_{42} in senile plaque cores in Alzheimer's disease.

C. Exley, 2006, Journal of Alzheimer's disease : JAD.

Comment on An assessment of comples formation between aluminum and silicic acid in acidic solutions

J. Birchall, C. Exley, 1995 .

Silicon species in seawater.

C. Exley, S. Sjöberg, 2014, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Intracellular tracing of amyloid vaccines through direct fluorescent labelling

C. Exley, Emma Shardlow, M. Mold, 2018, Scientific Reports.

Neurotoxicity of Aluminum

L. A. Bates, R. J. Boegman, C. Exley, 2018, Advances in Experimental Medicine and Biology.

The Chemistry of Human Exposure to Aluminium.

C. Exley, 2018, Advances in experimental medicine and biology.

Aluminum inhibition of hexokinase activity in vitro: a study in biological availability.

N. C. Price, J. Birchall, C. Exley, 1994, Journal of Inorganic Biochemistry.

iron and the Alzheimer's disease peptide Ferrous iron formation following the co-aggregation of ferric

J. Dobson, J. Collingwood, E. Céspedes, 2014 .

Amyloid, aluminium and the aetiology of Alzheimer's disease

C. Exley, 1996, The Medical journal of Australia.

Aluminium in the human brain

C. Exley, E. House, 2011 .

Aluminum affects neural phenotype determination of embryonic neural progenitor cells

H. Ulrich, M. Pillat, V. Morsch, 2019, Archives of Toxicology.

Human exposure to aluminium.

C. Exley, 2013, Environmental science. Processes & impacts.

Aluminium in Brain Tissue in Multiple Sclerosis

C. Linhart, A. King, C. Exley, 2018, International journal of environmental research and public health.

Aluminum exposure for 60days at human dietary levels impairs spermatogenesis and sperm quality in rats.

C. Exley, D. Vassallo, F. Peçanha, 2017, Reproductive Toxicology.

Aluminium adjuvants and adverse events in sub-cutaneous allergy immunotherapy

Christopher Exley, C. Exley, 2014, Allergy, Asthma & Clinical Immunology.

The toxicity of aluminium in humans La toxicité de l ’ aluminium chez l ’ homme

C. Exley, 2016 .

What is the risk of aluminium as a

C. Exley, 2014 .

The role of aluminum adjuvants in vaccines raises issues that deserve independent, rigorous and honest science.

L. Luján, F. Authier, C. Exley, 2020, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures.

C. Exley, O. Korchazhkina, 2001, Neuroreport.

Letter to the editor.

C. Exley, R. Gherardi, G. Crépeaux, 2017, Toxicology.

A reappraisal of biological silicification in plants?

C. Exley, G. Guerriero, 2019, The New phytologist.

Rough and tough. How does silicic acid protect horsetail from fungal infection?

C. Exley, C. Law, G. Guerriero, 2018, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Aluminum's preferential binding site in proteins: sidechain of amino acids versus backbone interactions.

X. López, C. Exley, S. J. Grabowski, 2017, Journal of inorganic biochemistry.