P. Spencer

P. Spencer, T. R. Van De Water, M. Bornstein, 1986, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Monitoring potential neurotoxic effects of hazardous waste disposal

J. Arezzo, P. Spencer, H. Schaumburg, 1983, Environmental health perspectives.

CLINICAL AND EXPERIMENTAL STUDIES OF DISTAL AXONOPATHY—A FREQUENT FORM OF BRAIN AND NERVE DAMAGE PRODUCED BY ENVIRONMENTAL CHEMICAL HAZARDS *

P. Spencer, H. Schaumburg, P. Spencer, 1979 .

STUDIES ON THE BIOCHEMICAL BASIS OF DISTAL AXONOPATHIES–I. INHIBITION OF GLYCOLYSIS BY NEUROTOXIC HEXACARBON COMPOUNDS

P. Spencer, M. Sabri, C. Moore, 1979, Journal of neurochemistry.

Toxic neuropathies

P. Spencer, H. Schaumburg, 1979, Neurology.

Feline nervous system response to chronic intoxication with commercial grades of methyl n-butyl ketone, methyl isobutyl ketone, and methyl ethyl ketone.

P. Spencer, H. Schaumburg, 1976, Toxicology and applied pharmacology.

Nervous system degeneration produced by acrylamide monomer.

P. Spencer, H. Schaumburg, Peter S. Spencer, 1975, Environmental health perspectives.

Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone.

P. Spencer, H. Schaumburg, Peter S. Spencer, 1975, Journal of neurology, neurosurgery, and psychiatry.

A Review of Acrylamide Neurotoxicity Part I. Properties, Uses and Human Exposure

P. Spencer, H. Schaumburg, 1974, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

Ultrastructural studies of the dying-back process II. The sequestration and removal by Schwann cells and oligodendrocytes of organelles from normal and diseased axons

P. Spencer, P. Thomas, P. Spencer, 1974, Journal of neurocytology.

An ultrastructural study of the inner core of the Pacinian corpuscle

P. Spencer, H. Schaumburg, P S Spencer, 1973, Journal of neurocytology.

Sodium cyanate alters glutathione homeostasis in rodent brain: relationship to neurodegenerative diseases in protein-deficient malnourished populations in Africa

P. Spencer, V. Palmer, A. Craig, 1999, Brain Research.

β‐N‐Oxalylamino‐l‐Alanine: Action on High‐Affinity Transport of Neurotransmitters in Rat Brain and Spinal Cord Synaptosomes

P. Spencer, D. Roy, S. Ross, 1985, Journal of neurochemistry.

Content of the neurotoxins cycasin (methylazoxymethanol beta-D-glucoside) and BMAA (beta-N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros.

G. Kisby, P. Spencer, M. Ellison, 1992, Neurology.

Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists.

P. Sindou, J. Hugon, P. Couratier, 1995, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.

1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy.

M. S. Kim, P. Spencer, R. Kayton, 2001, Toxicology and applied pharmacology.

Potential role of environmental genotoxic agents in diabetes mellitus and neurodegenerative diseases.

G. Kisby, P. Spencer, D. L. Eizirik, 1996, Biochemical pharmacology.

Direct and Indirect Neurotoxic Potential of Metal/Metalloids in Plants and Fungi Used for Food, Dietary Supplements, and Herbal Medicine

P. Spencer, V. Palmer, 2021, Toxics.

A comparison of muscarinic cholinergic involvement in the antinociceptive effects of morphine and clonidine in the mouse.

P. Spencer, J. Lipman, 1980, European journal of pharmacology.

COVID-19: neurological sequelae

A. Guekht, A. Buguet, G. Román, 2021, Health Risk Analysis.

Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment.

L. Nadel, J. Coyle, R. Schulte‐Hermann, 2008, Critical reviews in toxicology.

Lathyrism: a neurotoxic disease.

P. Spencer, H. Schaumburg, 1983, Neurobehavioral toxicology and teratology.

Recognizing neurotoxic disease

P. Spencer, H. Schaumburg, Peter S. Spencer, 1987, Neurology.

Aberrant PNS development in dystrophic mice

C. Raine, P. Spencer, H. J. Weinberg, 1975, Brain Research.

Early changes in degenerating mouse sciatic nerve are associated with endothelial cells

M. Miller, P. Spencer, A. Oaklander, 1987, Brain Research.

Schwann cell mitosis in response to regenerating peripheral axons in vivo

P. Spencer, R. Pellegrino, 1985, Brain Research.

Etiology of Retinal and Cerebellar Pathology in Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex

P. Spencer, 2020, Eye and brain.

Ultrastructural studies of the dying-back process. V. Axonal neurofilaments accumulate at sites of 2,5-hexanedione application: Evidence for nerve fibre dysfunction in experimental hexacarbon neuropathy

P. Spencer, M. Politis, P. Spencer, 1980, Journal of neurocytology.

TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice

X. Ren, P. Spencer, Benhong Xu, 2018, Front. Aging Neurosci..

Food Plant Chemicals Linked With Neurological and Neurodegenerative Disease

P. Spencer, V. Palmer, 2017 .

Case-Control Study of Nodding Syndrome in Acholiland: Urinary Multi-Mycotoxin Screening

R. Mazumder, P. Spencer, V. Palmer, 2021, Toxins.

Nodding syndrome phenotypes.

R. Mazumder, P. Spencer, V. Palmer, 2019, Revue neurologique.

Response to R. Colebunders: Helminth infections in Nodding syndrome

R. Mazumder, P. Spencer, V. Palmer, 2017, Journal of the Neurological Sciences.

Nodding syndrome: 2015 International Conference Report and Gulu Accord

A. Winkler, P. Spencer, D. Kitara, 2015, eNeurologicalSci.

Nodding syndrome in Kitgum District, Uganda: association with conflict and internal displacement

P. Spencer, V. Palmer, J. L. Landis, 2014, BMJ Open.

Clinical and epidemiologic characteristics of nodding syndrome in Mundri County, southern Sudan.

M. Anker, K. Vandemaele, P. Spencer, 2013, African health sciences.

Etiology of Alzheimer's disease: a western pacific view.

P. Spencer, 1990, Advances in neurology.

Studies on the aetiology and pathogenesis of motor neuron diseases. 1. Lathyrism: clinical findings in established cases.

A. Ludolph, J. Hugon, P. Spencer, 1987, Brain : a journal of neurology.

Degeneration in central and peripheral nervous systems produced by pure n-hexane: an experimental study.

P. Spencer, H. Schaumburg, Peter S. Spencer, 1976, Brain : a journal of neurology.

Motor neuron degeneration linked to excitatory amino acids: Histological and immunocytochemical approaches

J. Vallat, J. Hugon, P. Spencer, 1990 .

Toxic neuronal apoptosis and modifications of tau and APP gene and protein expressions.

J. Hugon, G. Kisby, P. Spencer, 1999, Drug metabolism reviews.

The neurotoxin, β-N-methylamino-l-alanine (BMAA) interacts with the strychnine-insensitive glycine modulatory site of the N-methyl-d-aspartate receptor

C. Allen, P. Spencer, I. Omelchenko, 1995, Neuropharmacology.

Pharmacological properties of centrally‐administered agents which interfere with neurotransmitter function: a comparison with the central depressant effects of ouabain

P. Spencer, P. Spencer, N. S. Doggett, 1973, British journal of pharmacology.

Activity of centrally acting and other drugs against tremor and hypothermia induced in mice by tremorine.

P. Spencer, 1965, British journal of pharmacology and chemotherapy.

PROCEEDINGS OF THE British Pharmacological Society

Reno, P. Spencer, H. N. S. DOGGETT, 1974 .

The fate of Schwann cells isolated from axonal contact

P. Spencer, H. J. Weinberg, P. Spencer, 1978, Journal of neurocytology.

A real-time medical cartography of epidemic disease (Nodding syndrome) using village-based lay mHealth reporters

P. Spencer, V. Palmer, D. Kitara, 2018, PLoS neglected tropical diseases.

Nodding Syndrome in the Spotlight - Placing Recent Findings in Perspective.

A. Winkler, P. Spencer, E. Schmutzhard, 2017, Trends in parasitology.

Nodding syndrome in Mundri county, South Sudan: environmental, nutritional and infectious factors.

M. Anker, K. Vandemaele, P. Spencer, 2013, African health sciences.

Plants with neurotoxic potential in undernourished subjects.

D. Tshala-Katumbay, P. Spencer, V. Palmer, 2019, Revue neurologique.

The enigma of litchi toxicity: an emerging health concern in southern Asia.

P. Spencer, V. Palmer, 2017, The Lancet. Global health.

U.S. Gulf War Veterans: service periods in theater, differential exposures, and persistent unexplained illness. Portland Environmental Hazards Research Centre.

D. Bourdette, A. Barkhuizen, P. Spencer, 1998, Toxicology letters.

Hypnotic activity of centrally--administered barbiturate and uncouplers of oxidative phosphorylation.

P. Spencer, R. Waite, N. S. Doggett, 1970, European journal of pharmacology.

Neuromuscular responses to pyridostigmine bromide in organotypic spinal cord-muscle culture

P. Spencer, F. Seil, R. Drake-Baumann, 1998, Journal of Physiology-Paris.

The perineurial window — a new model of focal demyelination and remyelination

C. Raine, P. Spencer, J. Prineas, 1975, Brain Research.

Biochemical Studies on 5′‐Nucleotidase of Schwann Cells in Degenerated Nerve

P. Spencer, M. Sabri, S. Ross, 1985, Journal of neurochemistry.

Regulation of myelination: Axons not required for the biosynthesis of basal levels of the major myelin glycoprotein by schwann cells in denervated distal segments of the adult cat sciatic nerve

P. Spencer, J. Poduslo, C. Berg, 1985, Journal of neuroscience research.

Isolation and Partial Characterization of Plasmalemma from Quiescent Schwann Cells in Denervated Cat Sciatic Nerve

P. Spencer, M. Sabri, S. Ross, 1983, Journal of neurochemistry.

The Regulation of Schwann-Cell Function in Degenerative Disorders of the Nervous System

P. Spencer, M. Sabri, M. Politis, 1983 .

A method to separate spatially the temporal sequence of axon-Schwann cell interaction during nerve regeneration

P. Spencer, M. Politis, P. Spencer, 1981, Journal of neurocytology.

Studies on the control of myelinogenesis. IV. Neuronal induction of Schwann cell myelin-specific protein synthesis during nerve fiber regeneration

N. Sternberger, P. Spencer, M. Politis, 1982, The Journal of neuroscience : the official journal of the Society for Neuroscience.

An in vivo assay of neurotropic activity

P. Spencer, M. Politis, 1983, Brain Research.

Discovery and partial characterization of primate motor-system toxins.

P. Nunn, A. Ludolph, J. Hugon, 1987, Ciba Foundation symposium.

Lathyrism in rural northwestern Ethiopia: a highly prevalent neurotoxic disorder.

P. Spencer, T. Alemu, R. T. Haimanot, 1990, International journal of epidemiology.

Lathyrus sativus (grass pea) and its neurotoxin ODAP.

P. Spencer, Yong‐Min Liang, Ze-Yi Yan, 2006, Phytochemistry.

Subcellular distribution of 2′,3′-cyclic nucleotide-3′-phosphodiesterase in cat peripheral nerve

P. Spencer, M. Sabri, S. Ross, 1985, Neurochemistry International.

Neuroprotein Targets of γ-Diketone Metabolites of Aliphatic and Aromatic Solvents That Induce Central–Peripheral Axonopathy

P. Spencer, 2020, Toxicologic pathology.

Interactions of oestrogenic and progestational steroids with dexamphetamine and fencamfamin in mice.

P. Spencer, A. Blackham, 1969, British journal of pharmacology.

Cyclic AMP-stimulated protein kinase activity in rabbit peripheral myelin

P. Spencer, V. Zabrenetzky, V. Krygier-Brévart, 2004, Neurochemical Research.

An in vivo method to prepare normal Schwann cells free of axons and myelin

P. Spencer, H. J. Weinberg, V. Zabrenetzky, 1979, Brain Research.

A single intravenous injection of doxorubicin (Adriamycin®) induces sensory neuronopathy in rats

E. Cho, P. Spencer, H. Schaumburg, 1980 .

Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex)

P. Spencer, V. Palmer, J. Reis, 2020, eNeurologicalSci.

Formaldehyde, DNA damage, ALS and related neurodegenerative diseases

P. Spencer, 2018, Journal of the Neurological Sciences.

Animal models for screening new agents.

P. Spencer, 1976, British journal of clinical pharmacology.

Tropical spastic paraparesis: HTLV-I antibodies in patients from the Seychelles.

A. Ludolph, J. Hugon, G. Román, 1987, The New England journal of medicine.

The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APPswe Cell Model of AD

P. Spencer, Feiqi Zhu, Xifei Yang, 2018, Front. Pharmacol..

Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote

P. Spencer, V. Palmer, J. Reis, 2020, eNeurologicalSci.

Antinociceptive activity of narcotic agonist and partial agonist analgesics and other agents in the tail-immersion test in mice and rats

P. Spencer, R. Sewell, 1976, Neuropharmacology.

Disorders of Peripheral Nerves

R. Katzman., P. Thomas, P. Spencer, 1984 .

Antinociceptive activitiy of narcotic agonist and partial agonist analgesics and other agents in the tail-immersion test in mice and rats.

P. Spencer, R. Sewell, 1976, Neuropharmacology.

Isolation and identification of two potent neurotoxins, aspartic acid and glutamic acid, from yellow star thistle (Centaurea solstitialis).

P. Spencer, D. Roy, D. Peyton, 1995, Natural toxins.

The epidemiology of lathyrism in north and central Ethiopia.

P. Spencer, T. Alemu, R. T. Haimanot, 1993, Ethiopian Medical Journal.

The neurology and neuropathology of the occupational neuropathies.

P. Spencer, H. Schaumburg, Peter S. Spencer, 1976, Journal of occupational medicine. : official publication of the Industrial Medical Association.

Experimental and clinical neurotoxicology

A. Ludolph, P. Spencer, H. Schaumburg, 1980 .

Chapter 18 Toxic disorders of the upper motor neuron system.

D. Tshala-Katumbay, P. Spencer, 2007, Handbook of clinical neurology.

Bioactivation of cyanide to cyanate in sulfur amino acid deficiency: relevance to neurological disease in humans subsisting on cassava.

P. Spencer, V. Palmer, M. Lasarev, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Determination of β-N-methylamino-l-alanine (BMAA) in plant (Cycas circinalis L.) and animal tissue by precolumn derivatization with 9-fluorenylmethyl chloroformate (FMOC) and reversed-phase high-performance liquid chromatography

G. Kisby, P. Spencer, D. Roy, 1988, Journal of Neuroscience Methods.

Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin.

P. Nunn, A. Ludolph, J. Hugon, 1987, Science.

Historical setting and neuropathology of lathyrism: Insights from the neglected 1944 report by Oliveras de la Riva

I. Ferrer, P. Spencer, S. Giménez‐Roldán, 2019, Journal of the history of the neurosciences.

Azañón's disease. A 19th century epidemic of neurolathyrism in Spain.

P. Spencer, S. Giménez‐Roldán, 2016, Revue neurologique.

Food toxins, ampa receptors, and motor neuron diseases.

P. Spencer, Peter S. Spencer, 1999, Drug metabolism reviews.

Studies on the control of myelinogenesis. II. Evidence for neuronal regulation of myelin production

P. Spencer, H. J. Weinberg, 1976, Brain Research.

Studies on the control of myelinogenesis. I. Myelination of regenerating axons after entry into a foreign unmyelinated nerve

P. Spencer, H. J. Weinberg, P. Spencer, 1975, Journal of neurocytology.

Aspartame: A Safety Evaluation Based on Current Use Levels, Regulations, and Toxicological and Epidemiological Studies

G. Williams, J. Doull, G. Burdock, 2007, Critical reviews in toxicology.

Pyridoxine megavitaminosis produces degeneration of peripheral sensory neurons (sensory neuronopathy) in the dog.

P. Spencer, H. Schaumburg, P. Thomann, 1981, Neurotoxicology.

The role of biogenic agents in the actions of centrally-acting analgesics.

P. Spencer, R. Sewell, 1977, Progress in medicinal chemistry.

Blockade of biogenic amine synthesis: its effect on the responses to leptazol and dexamphetamine in rats

P. Spencer, P. Spencer, T. A. Turner, 1969, British journal of pharmacology.

The pharmacological effects of ouabain administered intracerebrally to conscious mice.

P. Spencer, N. S. Doggett, T. A. Turner, 1970, British journal of pharmacology.

The Cycad Genotoxin MAM Modulates Brain Cellular Pathways Involved in Neurodegenerative Disease and Cancer in a DNA Damage-Linked Manner

L. Samson, R. Beyer, R. Fry, 2011, PloS one.

Animal models of brain maldevelopment induced by cycad plant genotoxins.

H. Moore, G. Kisby, P. Spencer, 2013, Birth defects research. Part C, Embryo today : reviews.

Western Pacific ALS-PDC: Evidence implicating cycad genotoxins

G. Kisby, P. Spencer, V. Palmer, 2020, Journal of the Neurological Sciences.

EFFECTS OF THALLIUM SALTS ON NEURONAL MITOCHONDRIA IN ORGANOTYPIC CORD-GANGLIA-MUSCLE COMBINATION CULTURES

C. Raine, P. Spencer, E. Peterson, 1973, The Journal of cell biology.

An expanded classification of neurotoxic responses based on cellular targets of chemical agents.

P. Spencer, H. Schaumburg, 1984, Acta neurologica Scandinavica. Supplementum.

Clinical and experimental neurotoxicity of 2‐t‐butylazo‐2‐hydroxy‐5‐methylhexane

P. Spencer, C. Beaubernard, T. L. Kurt, 1985, Annals of neurology.

Environmental, dietary and case-control study of Nodding Syndrome in Uganda: A post-measles brain disorder triggered by malnutrition?

D. Stadler, R. Mazumder, P. Spencer, 2016, Journal of the Neurological Sciences.

Single Doses of Acrylamide Reduce Retrograde Transport Velocity

P. Spencer, Matthew S. Miller, M. S. Miller, 1984, Journal of neurochemistry.

Tropism in nerve regeneration in vivo. Attraction of regenerating axons by diffusible factors derived from cells in distal nerve stumps of transected peripheral nerves

P. Spencer, M. Politis, K. Ederle, 1982, Brain Research.

The separation and identification of enolase isozymes of brain and sciatic nerve by high-pressure liquid anion-exchange chromatography

P. Spencer, A. Soiefer, M. Sabri, 1985, Brain Research.

Biochemical Mechanisms Underlying Primary Degeneration of Axons

P. Spencer, M. Sabri, Matthew S. Miller, 1985 .

Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy.

P. Spencer, Min-Sun Kim, M. Sabri, 2002, Toxicology and applied pharmacology.

The enlarging view of hexacarbon neurotoxicity.

G. Divincenzo, P. Spencer, H. Schaumburg, 1980, Critical reviews in toxicology.

An amyotrophic lateral sclerosis hot spot in the French Alps associated with genotoxic fungi

W. Camu, P. Spencer, V. Palmer, 2021, Journal of the Neurological Sciences.

The mechanisms of acrylamide axonopathy.

M. Miller, P. Spencer, M. Miller, 1985, Annual review of pharmacology and toxicology.

Genotoxic Damage During Brain Development Presages Prototypical Neurodegenerative Disease

G. Kisby, P. Spencer, 2021, Frontiers in Neuroscience.

ALS and environment: Clues from spatial clustering?

W. Camu, P. Spencer, E. Lagrange, 2019, Revue neurologique.

Environmental Neurotoxins Linked to a Prototypical Neurodegenerative Disease

G. Kisby, P. Spencer, V. Palmer, 2015 .

Unraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?

R. Fry, G. Kisby, P. Spencer, 2012, Front. Gene..

Is Neurodegenerative Disease a Long-Latency Response to Early-Life Genotoxin Exposure?

G. Kisby, P. Spencer, 2011, International journal of environmental research and public health.

Damage and repair of nerve cell DNA in toxic stress.

J. Hugon, G. Kisby, P. Spencer, 1999, Drug metabolism reviews.

Rapid induction of morphine dependence in the mouse by means of a modified pellet implantation

P. Leger, P. Spencer, N. Armstrong, 1983, The Journal of pharmacy and pharmacology.

Further studies on the pharmacological effects of pentobarbitone and 2,4-dinitrophenol injected into the cerebral ventricles of the mouse and rat.

P. Spencer, N. S. Doggett, 1973, European journal of pharmacology.

The Mammalian Peripheral Nervous System in Old Age

J. Ochoa, P. Spencer, 1981 .

Determination of polyamines by precolumn derivatization with 9-fluorenylmethyl chloroformate and reverse-phase high-performance liquid chromatography

G. Kisby, P. Spencer, A. Soiefer, 1989, Journal of Neuroscience Methods.

The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro

X. Ren, P. Spencer, Feiqi Zhu, 2018, Oxidative medicine and cellular longevity.

Toxic models of upper motor neuron disease

A. Ludolph, P. Spencer, 1996, Journal of the Neurological Sciences.

Experimental and Clinical

P. Spencer, 2000 .

Toxicity of Methyl n-Butyl Ketone

P. Spencer, H. Schaumburg, R. L. Raleigh, 1975 .

Thermoregulatory effects of intraventricular injection of noradrenaline in the mouse and the influence of ambient temperature

P. Spencer, S. Handley, 1972, The Journal of physiology.

Neurologic diseases associated with use of plant components with toxic potential.

A. Ludolph, G. Kisby, P. Spencer, 1993, Environmental research.

Pattern of Lathyrus sativus (grass pea) consumption and beta-N-oxalyl-α-β-diaminoproprionic acid (β-ODAP) content of food samples in the lathyrism endemic region of northwest ethiopia

P. Spencer, R. Tekle-Haimanot, B. Abegaz, 1993 .

Specific antagonism of behavioral action of “uncommon” amino acids linked to motor‐system diseases

P. Spencer, S. Ross, 1987, Synapse.

Lathyrus sativus L: the need for a strain lacking human and animal neurotoxic properties

P. Spencer, V. Palmer, M. Dwivedi, 1986 .

On the etiology and pathogenesis of chemically induced neurodegenerative disorders

A. Ludolph, C. Allen, G. Kisby, 1994, Neurobiology of Aging.

Lathyrism and western Pacific amyotrophic lateral sclerosis: etiology of short and long latency motor system disorders.

A. Ludolph, C. Allen, G. Kisby, 1991, Advances in neurology.

Studies on the etiology and pathogenesis of motor neuron diseases. II.

A. Ludolph, J. Hugon, P. Spencer, 1988, Neurology.

Specific antagonism of excitotoxic action of ‘uncommon’ amino acids assayed in organotypic mouse cortical cultures

P. Spencer, M. Seelig, S. Ross, 1987, Brain Research.

In vitro toxicological investigations of isoxazolinone amino acids of Lathyrus sativus.

M. Riepe, A. Ludolph, C. Allen, 1995, Natural toxins.

Toxic components of Lathyrus

P. Nunn, P. Spencer, D. Roy, 1986 .

Analgesic activity after intracerebral injection in the mouse.

P. Spencer, S. Handley, 1969, British journal of pharmacology.

Review of the pharmacology of existing antidepressants.

P. Spencer, 1977, British journal of clinical pharmacology.

Interaction of epinephrine and propranolol.

P. Spencer, L. Klein, 1986, Journal of the American Academy of Dermatology.

The effect of the endopeptidase inhibitor RB38A on hippocampal expression of APP mRNA isoforms

P. Spencer, R. Hutchings, R. Sewell, 1996 .

Interrelationships of undernutrition and neurotoxicity: food for thought and research attention.

P. Spencer, V. Palmer, 2012, Neurotoxicology.

ACTIONS OF PYRIDOSTIGMINE AND ORGANOPHOSPHATE AGENTS ON CHICK CELLS, MICE, AND CHICKENS*

P. Spencer, B. Wilson, J. D. Henderson, 2002, Drug and chemical toxicology.

Antidepressants and pain: a review of the pharmacological data supporting the use of certain tricyclics in chronic pain.

P. Spencer, R. Lee, 1977, The Journal of international medical research.

Studies on the biochemical basis of distal axonopathies. II. Specific inhibition of fructose-6-phosphate kinase by 2,5-hexanedione and methyl-butyl ketone

P. Spencer, Mohammad I. Sabri, Peter S. Spencer, 1979 .

Modification of the anti-nociceptive activity of morphine by centrally administered ouabain and dopamine

P. Spencer, N. S. Doggett, C. R. Calcutt, 2004, Psychopharmacologia.

Activities of narcotic and narcotic-antagonist analgesics following the intraventricular injection of various substances.

P. Spencer, C. R. Calcutt, 1971, British journal of pharmacology.

Probable Toxic Cause for Suspected Lychee-Linked Viral Encephalitis

R. Mazumder, P. Spencer, V. Palmer, 2015, Emerging infectious diseases.

The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas

P. Thomas, P. Spencer, 2004, Acta Neuropathologica.

Climatic Factors Under the Tropics

P. Handschumacher, P. Spencer, V. Palmer, 2018 .

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.

Ivan Rusyn, Kathleen F Kerr, Oksana Kosyk, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Analysis Of Neurotoxic Disease: The Acrylamide Experience

P. Spencer, H. Schaumburg, 1988 .

On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central--peripheral distal axonopathy.

P. Spencer, H. Schaumburg, M. Bischoff, 1978, Toxicology and applied pharmacology.

Human T-lymphotropic virus type I antibodies in the serum of patients with tropical spastic paraparesis in the Seychelles.

A. Ludolph, J. Hugon, G. Román, 1987, Archives of neurology.

Low‐dose oral copper treatment changes the hippocampal phosphoproteomic profile and perturbs mitochondrial function in a mouse model of Alzheimer's disease

X. Ren, P. Spencer, Ying Yang, 2019, Free radical biology & medicine.

Tropical spastic paraparesis in the Seychelles Islands

A. Ludolph, J. Hugon, G. Román, 1987, Neurology.

Seeking environmental causes of neurodegenerative disease and envisioning primary prevention.

G. Kisby, P. Spencer, V. Palmer, 2016, Neurotoxicology.

Medical management, prevention and mitigation of environmental risks factors in Neurology.

M. Giroud, G. Román, P. Spencer, 2019, Revue neurologique.

Axotomy-induced ornithine decarboxylase activity in the mouse dorsal root ganglion is inhibited by the vinca alkaloids

P. Spencer, A. Moretto, A. Soiefer, 1988, Neurochemical Research.

Proteomic Profile of Mouse Brain Aging Contributions to Mitochondrial Dysfunction, DNA Oxidative Damage, Loss of Neurotrophic Factor, and Synaptic and Ribosomal Proteins

P. Spencer, Feiqi Zhu, Xifei Yang, 2020, Oxidative medicine and cellular longevity.

Ultrastructural studies of the dying-back process. IV. Differential vulnerability of PNS and CNS fibers in experimental central-peripheral distal axonopathies.

P. Spencer, H. Schaumburg, Peter S. Spencer, 1977, Journal of neuropathology and experimental neurology.

Flavanol-rich lychee fruit extract substantially reduces progressive cognitive and molecular deficits in a triple-transgenic animal model of Alzheimer disease

P. Spencer, Benhong Xu, Xifei Yang, 2019, Nutritional neuroscience.

Proteomic alterations of brain subcellular organelles caused by low-dose copper exposure: implication for Alzheimer’s disease

X. Ren, P. Spencer, Benhong Xu, 2018, Archives of Toxicology.

Interprofessional global health education in a cosmopolitan community of North America: the iCHEE experience.

R. Mazumder, P. Spencer, V. Palmer, 2014, Academic medicine : journal of the Association of American Medical Colleges.

Reappraisal of the model for "bulk axoplasmic flow".

P. Spencer, 1972, Nature: New biology.

Effects of centrally acting drugs on exploratory behaviour in rats.

P. Spencer, P S Spencer, A S Marriott, 1965, British journal of pharmacology and chemotherapy.

Rapid reorganization of the axonal cytoskeleton induced by a gamma diketone

P. Spencer, J. C. Zagoren, M. Politis, 1983, Brain Research.

Ultrastructural Studies of the Dying‐back Process: VI. Examination of Nerve Fibers Undergoing Giant Axonal Degeneration in Organotypic Culture

P. Spencer, B. Veronesi, M. Bornstein, 1983, Journal of neuropathology and experimental neurology.

Nervous system dying-back disease produced by 2,5-hexanedione.

P. Spencer, H. Schaumburg, 1975, Transactions of the American Neurological Association.

Health of Vulnerable Populations.

P. Spencer, V. Palmer, Kathleen I Birchfield, 2018, Academic medicine : journal of the Association of American Medical Colleges.

Clinical and electrophysiologic features of pyramidal dysfunction in macaques fed Lathyrus satiuus and IDPN

A. Ludolph, J. Hugon, P. Spencer, 2006 .

Alzheimer Pathology and Angiotension

E. Shapiro, H. Chui, I. Hajjar, 2016 .

Parkinsonism and cancer.

G. Kisby, P. Spencer, 2013, JAMA neurology.

Contrasting actions of acute or chronic paroxetine and fluvoxamine on morphine withdrawal-induced place conditioning.

P. Spencer, M. Rafieian-kopaei, R. Sewell, 1995, European journal of pharmacology.

A tissue culture model of methyl ethyl ketone's potentiation of n-hexane neurotoxicity.

P. Spencer, B. Veronesi, A. Lington, 1984, Neurotoxicology.

Nervous system responses of rats to subchronic inhalation of n-hexane and n-hexane + methyl-ethyl-ketone mixtures

P. Spencer, G. Stoltenburg, H. Altenkirch, 1982, Journal of the Neurological Sciences.

Aromatic as well as aliphatic hydrocarbon solvent axonopathy.

P. Spencer, M. Sabri, Min Sun Kim, 2002, International journal of hygiene and environmental health.

Environmental hydrocarbons produce degeneration in cat hypothalamus and optic tract.

P. Spencer, H. Schaumburg, Peter S. Spencer, 1978, Science.

Methyl N-Butyl ketone

P. Spencer, H. Schaumburg, R. L. Raleigh, 1975 .

Letter: Toxicity of Methyl n-Butyl Ketone.

P. Spencer, H. Schaumburg, R. L. Raleigh, 1975, Archives of environmental health.

Central and peripheral nervous system degeneration produced by pure n-hexane.

P. Spencer, H. Schaumburg, 1976, Transactions of the American Neurological Association.

Distal axonopathy: one common type of neurotoxic lesion.

P. Spencer, H. Schaumburg, 1978, Environmental health perspectives.

Monocyclic and dicyclic hydrocarbons: structural requirements for proximal giant axonopathy

D. Tshala-Katumbay, P. Spencer, V. Palmer, 2006, Acta Neuropathologica.

Computational insights into the chemical structures and mechanisms of the chromogenic and neurotoxic effects of aromatic γ-diketones

D. Dixon, P. Spencer, Chang-Guo Zhan, 2003 .

Neurotoxic fragrance produces ceroid and myelin disease.

P. Spencer, D. Horoupian, A. Sterman, 1979, Science.

Neurotoxic properties of musk ambrette.

P. Spencer, R. A. Ford, D. Opdyke, 1984, Toxicology and Applied Pharmacology.

Mechanisms of Selective Toxicity in Neurodegenerative Disorders

P. Spencer, 2000 .

Experimental myelin disease and ceroid accumulation produced by the fragrance compound acetyl ethyl tetramethyl tetralin.

P. Spencer, D. Horoupian, A. Sterman, 1978, Transactions of the American Neurological Association.

Mitochondrial Molecular Abnormalities Revealed by Proteomic Analysis of Hippocampal Organelles of Mice Triple Transgenic for Alzheimer Disease

X. Ren, P. Spencer, Jian-Zhi Wang, 2018, Front. Mol. Neurosci..

Detecting drug effects on short-term memory function using a combined delayed matching and non-matching to position task.

P. Spencer, R. Sewell, D. Pache, 1999, Journal of pharmacological and toxicological methods.

SARS-CoV-2 infection and sleep disturbances: nitric oxide involvement and therapeutic opportunity.

A. Buguet, G. Román, P. Spencer, 2021, Sleep.

Nodding Syndrome – An Investment Case for Global Health?

A. Winkler, P. Spencer, E. Schmutzhard, 2018 .

Nodding syndrome: origins and natural history of a longstanding epileptic disorder in sub-Saharan Africa.

P. Spencer, V. Palmer, L. Jilek‐Aall, 2013, African health sciences.

Antidepressant inhibitory activity in the abdominal constriction assay is competitively blocked by opioid antagonists

P. Spencer, R. Sewell, A. Gray, 1990 .

The effect of clomipramine and other amine-uptake inhibitors on morphine analgesia in laboratory animals.

P. Spencer, R. Lee, 1977, Postgraduate medical journal.

AN EXAMINATION OF TOLERANCE TO THE ANTINOCICEPTIVE EFFECTS OF MORPHINE, CLONIDINE AND THEIR COMBINATION IN THE MOUSE TAIL IMMERSION TEST

P. Spencer, J. Lipman, 1980 .

A comparison of the acute toxicity of some centrally acting drugs measured under crowded and uncrowded conditions.

P. Spencer, N. S. Doggett, H. Reno, 1977, Toxicology and Applied Pharmacology.

Meptazinol activity on morphine-naive and morphine-dependent guinea-pig ileum: correlation with in vivo studies.

J. P. Gonzalez, P. Spencer, R. Sewell, 1984, Alcohol and alcoholism.

Increase of ATP levels by glutamate antagonists is unrelated to neuroprotection

M. Riepe, A. Ludolph, P. Spencer, 1994, NeuroReport.

Disorders of peripheral nerves : an introductory text

P. Thomas, P. Spencer, H. Schaumburg, 1983 .

The antagonism of oxotremorine effects in the mouse by thymoleptics.

P. Spencer, 1966, Life sciences.

Identification of endogenous phosphorylation sites of bovine medium and low molecular weight neurofilament proteins by tandem mass spectrometry.

M. Deinzer, P. Spencer, S. Trimpin, 2004, Biochemistry.

Rapid intracerebroventricular injection assisted by an automatic syringe.

P. Spencer, J. Lipman, Jonathan J. Lipman, 1980, Journal of pharmacological methods.

Effect of exogenous pyruvate on acrylamide neuropathy in rats

P. Spencer, W. Dairman, M. Sabri, 1989, Brain Research.

Acrylamide impairs fast and slow axonal transport in rat optic system

P. Spencer, M. Sabri, 1990, Neurochemical Research.

How does acrylamide perturb axon transport and induce nerve fiber degeneration? Commentary on forum position paper.

P. Spencer, M. Sabri, 2002, Neurotoxicology.

β-N-Methylamino-l-alanine in the presence of bicarbonate is an agonist at non- N-methyl-d-aspartate-type receptors

D. Carpenter, C. Allen, P. Spencer, 1993, Neuroscience.

Hind limb somatosensory evoked potentials in the monkey: The effects of distal axonopathy

H. Vaughan, J. Arezzo, P. Spencer, 1982, Annals of neurology.

Content of the neurotoxins cycasin (methylazoxymethanol β‐D‐glucoside) and BNLAA (β‐N‐methylamino‐L‐alanine) in cycad flour prepared by Guam Chamorros

G. Kisby, P. Spencer, M. Ellison, 1992, Neurology.

Recent Advances in Nervous System Toxicology

P. Spencer, L. Manzo, C. Galli, 1988, NATO ASI Series.

A TISSUE CULTURE MODEL OF DISTAL, (DYING-BACK) AXONOPATHY — ITS USE IN DETERMINING PRIMARY NEUROTOXIC HEXACARBON COMPOUNDS

G. Divincenzo, P. Spencer, B. Veronesi, 1978 .

Organic solvent neurotoxicity. Facts and research needs.

P. Spencer, H. Schaumburg, P S Spencer, 1985, Scandinavian journal of work, environment & health.

Does the cycad genotoxin MAM implicated in Guam ALS-PDC induce disease-relevant changes in mouse brain that includes olfaction?

R. Fry, M. Iordanov, G. Kisby, 2011, Communicative & integrative biology.

Dysregulation of Myosin Complex and Striated Muscle Contraction Pathway in the Brains of ALS-SOD1 Model Mice.

P. Spencer, Benhong Xu, Xifei Yang, 2019, ACS chemical neuroscience.

Structure and function of the somatosensory system: a neurotoxicological perspective.

J C Arezzo, J. Arezzo, P. Spencer, 1982, Environmental health perspectives.

Studies of the primate somatosensory system in experimental acrylamide intoxication.

J. Arezzo, P. Spencer, H. Schaumburg, 1985, Neurotoxicology.

Regeneration of rat optic axons into peripheral nerve grafts

P. Spencer, M. Politis, Peter S. Spencer, 1986, Experimental Neurology.

μ‐ AND κ‐OPIOID ANTINOCICEPTION ENHANCED IN THE PRESENCE OF D‐2 BUT NOT D‐1 DOPAMINE ANTAGONISTS IN THE MOUSE

P. Spencer, R. Sewell, K. Rooney, 1986 .

Guam ALS-PDC: possible causes.

P. Nunn, A. Ludolph, J. Hugon, 1993, Science.

Excitatory Amino Acid‐induced Changes in Amygdaloid and Hippocampal APP mRNA Expression: Effect of Selective Antagonists

G. Foster, P. Spencer, R. Hutchings, 2011 .

Barbiturate-induced sleep in hyperthyroid mice.

P. Spencer, R. Waite, 1970, European journal of pharmacology.

Nodding episodes and high anion gap in a 13 year old child with nodding syndrome: a case report.

P. Spencer, V. Palmer, D. Kitara, 2015 .

Jean Rodier: History of Manganism in Morocco.

P. Spencer, J. Reis, F. Belahsen, 2020, Neurotoxicology.

Differentiation of potent μ- and κ-opiate agonists using heat and pressure antinociceptive profiles and combined potency analysis

N. Upton, P. Spencer, R. Sewell, 1982 .

Interactions of aging and environmental agents: the toxicological perspective.

S. M. Stahl, R. Carchman, J. Borzelleca, 1987, Progress in clinical and biological research.

Addendum: Standardizing global gene expression analysis between laboratories and across platforms

Roger E Bumgarner, H. Dressman, R. Tennant, 2005, Nature Methods.

Neurotoxic Properties of Certain Aliphatic Hexacarbons

P. Spencer, Herbert H Schaumburg, 1977, Proceedings of the Royal Society of Medicine.

Disruption of Axoplasmic Transport by Neurotoxic Agents. The 2,5-Hexanedione Model

P. Spencer, J. Griffin, 1982 .

Some aspects of the pharmacology of analgesia.

P. Spencer, 1976, Journal of International Medical Research.

Plant‐Derived Neurotoxic Amino Acids (β‐N‐Oxalylamino‐l‐Alanine and β‐N‐Methylamino‐l‐Alanine): Effects on Central Monoamine Neurons

L. Olson, P. Mouton, P. Spencer, 1990 .

Plant-derived neurotoxic amino acids (beta-N-oxalylamino-L-alanine and beta-N-methylamino-L-alanine): effects on central monoamine neurons.

L. Olson, P. Mouton, P. Spencer, 1990, Journal of neurochemistry.

Excitotoxic disorders.

R. G. Allen, A. Ludolph, G. Kisby, 1990, Science.

Excitotoxic disorders [1]

R. G. Allen, A. Ludolph, G. Kisby, 1990 .

Non Print Items Author and Co-author Contact Information

P. Spencer, P. Lein, 2013 .

PHOSPHOINOSITIDE METABOLISM IN PERIPHERAL AXONS

R. Lasek, P. Spencer, R. Gould, 1978 .

Studies of the etiology and pathogenesis of motor neuron diseases: III. Magnetic cortical stimulation in patients with lathyrism

A. Ludolph, J. Hugon, P. Spencer, 1993, Acta neurologica Scandinavica.

Neurologic Diseases Associated with Use of Plant Components with Toxic Potential1

A. Ludolph, G. Kisby, P. Spencer, 1994 .

Differentiation of potent mu and kappa-opiate agonists using heat and pressure antinociceptive profiles and combined potency analysis.

N. Upton, P. Spencer, R. Sewell, 1982, European journal of pharmacology.

PATHOLOGICAL CHANGES IN SPINAL CORD INDUCED BY LATHYRUS NEUROTOXIN (BETA-(N)-OXALYLAMINO L-ALANINE) IN VITRO

P. Spencer, D. Roy, M. Bornstein, 1985 .

THE CNS DISTAL AXONOPATHY IN DOGS INTOXICATED WITH CLIOQUINOL

P. Spencer, H. Schaumburg, P. Thomann, 1978 .

Proceedings: Modification of the antinociceptive activity of narcotic agonists and antagonists by intraventricular injection of biogenic amines in mice.

P. Spencer, R. Sewell, 1974, British Journal of Pharmacology.

Modification of morphine analgesia in the rat by biogenic amines administered intraventricularly.

P. Spencer, C. Sparkes, 1969, British journal of pharmacology.

Anti-nociceptive activity of narcotic agonists and partial agonists in mice given biogenic amines by intracerebroventricular injection

P. Spencer, R. Sewell, 1975, Psychopharmacologia.

Reply: NOTES AND LETTERS

G. Román, P. Spencer, B. Schoenberg, 1986 .

Determination of beta-N-methylamino-L-alanine (BMAA) in plant (Cycas circinalis L.) and animal tissue by precolumn derivatization with 9-fluorenylmethyl chloroformate (FMOC) and reversed-phase high-performance liquid chromatography.

G. Kisby, P. Spencer, D. Roy, 1988, Journal of Neuroscience Methods.

Cycad Genotoxin Methylazoxymethanol Disrupts the Brain Ubiquitin-Proteasome Pathway, Tau and α-Synuclein, as Reported in ALS-PDC.

G. Kisby, P. Spencer, J. Eriksen, 2021, Journal of Neuropathology and Experimental Neurology.

Volatile metabolites in sera of normal and diabetic patients.

D. Bafus, P. Spencer, C. Poole, 1980, Journal of chromatography.

Environmental Neurology has become a hot topic.

Y. Béjot, M. Giroud, P. Spencer, 2019, Revue neurologique.

Action of acrylamide on selected enzymes of energy metabolism in denervated cat peripheral nerves

P. Spencer, M. Sabri, S. Ross, 1985, Brain Research.

Monitoring potential neurotoxic effects of hazardous waste disposal

J. Arezzo, P. Spencer, H. Schaumburg, 1983, Environmental Health Perspectives.