Hitoshi Kawashima

发表

Impact of quality trimming on the efficiency of reads joining and diversity analysis of Illumina paired-end reads in the context of QIIME1 and QIIME2 microbiome analysis frameworks

Kenji Mizuguchi, Yi-An Chen, Attayeb Mohsen, 2019, BMC Bioinformatics.

Gut microbial composition in patients with atrial fibrillation: effects of diet and drugs

K. Mizuguchi, K. Hirata, H. Murakami, 2020, Heart and Vessels.

Constructing an in silico three-class predictor of human intestinal absorption with Caco-2 permeability and dried-DMSO solubility.

K. Mizuguchi, Tsuyoshi Esaki, C. Nagao, 2019, Journal of pharmaceutical sciences.

Development of an in silico prediction system of human renal excretion and clearance from chemical structure information incorporating fraction unbound in plasma as a descriptor

K. Mizuguchi, Tsuyoshi Esaki, C. Nagao, 2019, Scientific Reports.

Discovery of a novel and potent human and rat beta3-adrenergic receptor agonist, [3-[(2R)-[[(2R)-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1H-indol-7-yloxy]acetic acid.

Hitoshi Kawashima, S. Kato, Kenji. Suzuki, 2005, Chemical & pharmaceutical bulletin.

Novel and potent human and rat beta3-adrenergic receptor agonists containing substituted 3-indolylalkylamines.

Hitoshi Kawashima, S. Kato, Kenji. Suzuki, 2003, Bioorganic & medicinal chemistry letters.

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota

K. Mizuguchi, Yi-an Chen, Y. Yonejima, 2022, Nature Communications.

A novel adipokine GM2AP impairs insulin signaling.

Hitoshi Kawashima, Toru Kimura, Toru Yamada, 2010, Biochemical and biophysical research communications.

Comprehensive analysis of gut microbiota of a healthy population and covariates affecting microbial variation in two large Japanese cohorts

K. Mizuguchi, Yi-an Chen, T. Nakagata, 2020, BMC microbiology.

Utilizing public and private sector data to build better machine learning models for the prediction of pharmacokinetic parameters.

K. Mizuguchi, Tsuyoshi Esaki, T. Honma, 2022, Drug discovery today.

Dietary Vitamin B1 Intake Influences Gut Microbial Community and the Consequent Production of Short-Chain Fatty Acids

K. Mizuguchi, Yi-an Chen, T. Kubota, 2022, Nutrients.

Identification of Human Gut Microbiome Associated with Enterolignan Production

K. Mizuguchi, Yi-an Chen, T. Nakagata, 2022, Microorganisms.

Computational Model To Predict the Fraction of Unbound Drug in the Brain

Kenji Mizuguchi, Hitoshi Kawashima, Yayoi Natsume-Kitatani, 2019, J. Chem. Inf. Model..

Predicting Fraction Unbound in Human Plasma from Chemical Structure: Improved Accuracy in the Low Value Ranges.

Kenji Mizuguchi, Hitoshi Kawashima, Yayoi Natsume-Kitatani, 2018, Molecular pharmaceutics.

Classification of the Occurrence of Dyslipidemia Based on Gut Bacteria Related to Barley Intake

K. Mizuguchi, Z. Yamagata, H. Murakami, 2022, Frontiers in Nutrition.

Relationships between barley consumption and gut microbiome characteristics in a healthy Japanese population: a cross-sectional study

K. Mizuguchi, Z. Yamagata, H. Murakami, 2021, BMC Nutrition.

Relationship between Human Gut Microbiota and Nutrition Intake in Hypertensive Discordant Monozygotic Twins

K. Mizuguchi, J. Kunisawa, Jonguk Park, 2021 .

Relationship between Nutrient Intake and Human Gut Microbiota in Monozygotic Twins

K. Mizuguchi, J. Kunisawa, Y. Iwatani, 2021, Medicina.

MANTA, an integrative database and analysis platform that relates microbiome and phenotypic data

Kenji Mizuguchi, Yi-An Chen, Attayeb Mohsen, 2020, PloS one.

Auto-q: Qiime Analysis automating script

K. Mizuguchi, Yi-an Chen, Attayeb Mohsen, 2019 .

Compact, Automated, Inexpensive, and Field-Deployable Vacuum-Outlet Gas Chromatograph for Trace-Concentration Gas-Phase Organic Compounds.

Hitoshi Kawashima, D. Gentner, F. Xiong, 2019, Analytical chemistry.

Impact of quality trimming on the efficiency of reads joining and diversity analysis of Illumina paired-end reads in the context of QIIME1 and QIIME2 microbiome analysis frameworks

K. Mizuguchi, Yi-an Chen, Attayeb Mohsen, 2019, BMC Bioinformatics.

Characteristic Gut Bacteria in High Barley Consuming Japanese Individuals without Hypertension

K. Mizuguchi, Z. Yamagata, H. Murakami, 2023, Microorganisms.

Discovery of a Novel and Potent Human and Rat β3‐Adrenergic Receptor Agonist, [3‐[(2R)‐[ [(2R)‐(3‐Chlorophenyl)‐2‐hydroxyethyl]amino]propyl]‐1H‐indol‐7‐yloxy] acetic Acid.

Hitoshi Kawashima, S. Kato, Kenji. Suzuki, 2005 .

Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance

Kenji Mizuguchi, Hitoshi Kawashima, Yayoi Natsume-Kitatani, 2018, Molecular informatics.

A public-private partnership to enrich the development of in silico predictive models for pharmacokinetic and cardiotoxic properties.

K. Mizuguchi, T. Honma, Tomohiro Sato, 2021, Drug discovery today.

The prediction of food effect on drug oral absorption by machine learning

Hitoshi Kawashima, Reiko Watanabe, Masataka Kuroda, 2020 .

Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration.

K. Mizuguchi, Tsuyoshi Esaki, Hitoshi Kawashima, 2021, Journal of medicinal chemistry.