J. Kao

发表

The gut microbiome in health and in disease

V. Young, A. Shreiner, J. Kao, 2015, Current opinion in gastroenterology.

Helicobacter pylori directs tolerogenic programming of dendritic cells

J. Kao, Min Zhang, Maochang Liu, 2010, Gut microbes.

Association between Helicobacter pylori and Barrett's esophagus, erosive esophagitis, and gastroesophageal reflux symptoms.

P. Schoenfeld, J. Rubenstein, J. Inadomi, 2014, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Associations of diabetes mellitus, insulin, leptin, and ghrelin with gastroesophageal reflux and Barrett's esophagus.

H. Morgenstern, L. McMahon, P. Schoenfeld, 2013, Gastroenterology.

Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation

B. Zhu, L. Duan, J. Kao, 2021, Acta Pharmacologica Sinica.

Helicobacter pylori Outer Membrane Protein 18 (Hp1125) Induces Dendritic Cell Maturation and Function

J. Merchant, J. Kao, Sivaprakash Rathinavelu, 2005, Helicobacter.

Aim2-Mediated/IFN-β-Independent Regulation of Gastric Metaplastic Lesions via CD8+ T Cells.

Henry R. Haley, G. Luker, M. Cascalho, 2020, JCI insight.

Gli1 Deletion Prevents Helicobacter-Induced Gastric Metaplasia and Expansion of Myeloid Cell Subsets

J. Merchant, J. Kao, L. Bai, 2013, PloS one.

Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma

J. Merchant, W. Kang, J. Kao, 2005, Oncogene.

A little O2 may go a long way in structuring the GI microbiome.

T. Schmidt, J. Kao, 2014, Gastroenterology.

Effective Colorectal Cancer Education for Asian Americans: A Michigan Program

J. Kao, H. Hsieh, D. Oakley, 2010, Journal of Cancer Education.

Role of Dietary Metabolites in Regulating the Host Immune Response in Gastrointestinal Disease

J. Kao, M. El–Zaatari, M. El-Zaatari, 2017, Front. Immunol..

Contributions From Gastroenterology: Acid Peptic Disorders, Barrett's Esophagus and Eosinophilic Esophagitis.

J. Rubenstein, R. Souza, I. Hirano, 2018, Gastroenterology.

Chemotaxis Allows Bacteria To Overcome Host-Generated Reactive Oxygen Species That Constrain Gland Colonization

K. Ottemann, J. Kao, Shuai Hu, 2017, Infection and Immunity.

Somatostatin inhibits dendritic cell responsiveness to Helicobacter pylori

J. Merchant, J. Kao, Sivaprakash Rathinavelu, 2006, Regulatory Peptides.

Response to Fujita and Kapoor

H. Morgenstern, L. McMahon, J. Rubenstein, 2009, The American Journal of Gastroenterology.

IRAK-M modulates expression of IL-10 and cell surface markers CD80 and MHC II after bacterial re-stimulation of tolerized dendritic cells.

T. Standiford, J. Kao, J. Luther, 2012, Immunology letters.

Aberrant T helper cell response in tumor-bearing mice limits the efficacy of dendritic cell vaccine.

Min Zhang, J. Kao, Chuan-min Chen, 2006, Immunology letters.

Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity.

A. Bass, R. Bowlby, W. Leung, 2018, Gastroenterology.

Structure and function of the human microbiome: implications for health and disease

V. Young, J. Kao, Allen A. Lee, 2022, Yamada's Textbook of Gastroenterology.

The Role of Dendritic Cells in the Development of Acute Dextran Sulfate Sodium Colitis

Gwo-hsiao Chen, G. Huffnagle, J. Kao, 2007 .

The Role of Dendritic Cells in the Development of Acute Dextran Sulfate Sodium Colitis1

Min Zhang, Gwo-hsiao Chen, G. Huffnagle, 2007, The Journal of Immunology.

Sodium Colitis Development of Acute Dextran Sulfate The Role of Dendritic Cells in the

Min Zhang, Gwo-hsiao Chen, G. Huffnagle, 2007 .

Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection.

J. Merchant, D. J. Law, J. Kao, 2006, Gastroenterology.

Overview of gut immunology.

G. Huffnagle, J. Kao, K. L. Mason, 2008, Advances in experimental medicine and biology.

Regional Control of Regulatory Immune Cells in the Intestine

J. Kao, N. Kamada, A. Hayashi, 2018, Current Pathobiology Reports.

Reverse Microbiomics: A New Reverse Dysbiosis Analysis Strategy and Its Usage in Prediction of Autoantigens and Virulent Factors in Dysbiotic Gut Microbiomes From Rheumatoid Arthritis Patients

Y. He, Haihe Wang, Edison Ong, 2021, Frontiers in Microbiology.

Inflammation and cancer III. Somatostatin and the innate immune system.

J. Merchant, J. Kao, Y. Zavros, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Helicobacter pylori-secreted factors inhibit dendritic cell IL-12 secretion: a mechanism of ineffective host defense.

J. Merchant, J. Kao, Sivaprakash Rathinavelu, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Effects of Helicobacter pylori treatment on the incidences of autoimmune diseases and inflammatory bowel disease in patients with diabetes mellitus

Deng-Chyang Wu, J. Kao, Kun-Der Lin, 2022, PloS one.

Proton Pump Inhibitor-Induced Gut Dysbiosis Increases Mortality Rates for Patients with Clostridioides difficile Infection

Yun-Shien Lee, S. Hsieh, J. Kao, 2022, Microbiology spectrum.

VSL#3 Prevents Ulcerative Colitis Carcinogenesis in Mice and Cell by Regulating Inflammatory and Wnt/β-catenin Pathway

Jingnan Li, J. Kao, Xiaomin Hu, 2020 .

Distinct Physiological Characteristics of Isolated Laryngopharyngeal Reflux Symptoms.

Yung-An Tsou, M. Vaezi, Chi-Sen Chang, 2020, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

IL-10 produced by macrophages regulates epithelial integrity in the small intestine

K. Honda, K. Atarashi, A. Nusrat, 2019, Scientific Reports.

Rifaximin alters intestinal bacteria and prevents stress-induced gut inflammation and visceral hyperalgesia in rats.

J. Kao, M. Gillilland, C. Owyang, 2014, Gastroenterology.

Reply.

Deng-Chyang Wu, J. Kao, 2019, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

TLR2 Mediates Helicobacter pylori–Induced Tolerogenic Immune Response in Mice

Min Zhang, W. Zou, J. Kao, 2013, PloS one.

CCR2 mediates Helicobacter pylori‐induced immune tolerance and contributes to mucosal homeostasis

J. Kao, M. El–Zaatari, Min F Zhang, 2017, Helicobacter.

Expression of a soluble TGF-β receptor by tumor cells enhances dendritic cell/tumor fusion vaccine efficacy.

Jing Chen, J. Kao, M. Zhang, 2008, The Journal of Immunology.

Sa1285 The Prevalence of ADHD in Adults and Children Previously Diagnosed With Celiac Disease: A Hospital-Based Study

J. Rubenstein, J. Kao, Lynn P. Holevinski, 2013 .

Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice.

V. Young, G. Huffnagle, J. Kao, 2013, Gastroenterology.

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine.

J. Merchant, A. Shreiner, J. Kao, 2015, Gastroenterology.

Catechins and Sialic Acid Attenuate Helicobacter pylori-Triggered Epithelial Caspase-1 Activity and Eradicate Helicobacter pylori Infection

C. Shun, Hung‐Chih Yang, J. Kao, 2013, Evidence-based complementary and alternative medicine : eCAM.

Probiotic mixture VSL#3 prevents ulcerative colitis-associated carcinogenesis in mice and cells by regulating the inflammatory and Wnt/β-catenin pathway.

Jingnan Li, J. Kao, C. Owyang, 2022, Chinese medical journal.

The tuning of the gut nervous system by commensal microbiota.

J. Kao, N. Kamada, 2013, Gastroenterology.

Patients with breath test positive are necessary to be identified from irritable bowel syndrome: a clinical trial based on microbiomics and rifaximin sensitivity

J. Kao, Lu Zhang, Mo Li, 2022, Chinese medical journal.

Human Gastric Epithelial Cells Contribute to Gastric Immune Regulation by Providing Retinoic Acid to Dendritic Cells

P. Mannon, K. Mönkemüller, P. Harris, 2014, Mucosal Immunology.

Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation

K. Krause, D. Lodygin, A. Bowie, 2021, Science Signaling.

Tryptophan Catabolism Restricts IFN-γ–Expressing Neutrophils and Clostridium difficile Immunopathology

R. Lutter, V. Young, G. Huffnagle, 2014, The Journal of Immunology.

Dietary L-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut

A. Hirayama, N. Barnich, C. Alteri, 2019, Nature Microbiology.

Interplay between the Gastric Bacterial Microbiota and Candida albicans during Postantibiotic Recolonization and Gastritis

V. Young, G. Huffnagle, J. Kao, 2011, Infection and Immunity.

A report of nonexistence of the non-Helicobacter pylori Helicobacter species in Iranian patients suffering from inflammatory bowel disease

M. Zali, J. Kao, M. Azimirad, 2021, Folia Microbiologica.

Prior Helicobacter pylori infection ameliorates Salmonella typhimurium‐induced colitis: Mucosal crosstalk between stomach and distal intestine

Min Zhang, P. Higgins, L. Johnson, 2011, Inflammatory bowel diseases.

Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitis

J. Rubenstein, J. Erb-Downward, J. Kao, 2011, Gut.

Association between Helicobacter pylori infection and inflammatory bowel disease: A meta‐analysis and systematic review of the literature†

M. Dave, P. Higgins, J. Kao, 2010, Inflammatory bowel diseases.

Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice.

Mark J. Miller, Min Zhang, M. Miller, 2010, Gastroenterology.

High-dose dual therapy is superior to standard first-line or rescue therapy for Helicobacter pylori infection.

Chien-Wei Lu, M. Shieh, J. Wong, 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Candida albicans and Bacterial Microbiota Interactions in the Cecum during Recolonization following Broad-Spectrum Antibiotic Therapy

V. Young, G. Huffnagle, J. Kao, 2012, Infection and Immunity.

DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk.

A. Magis, G. Omenn, M. Conomos, 2021, The Journal of clinical investigation.

Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent Clostridium difficile infection.

V. Young, J. Kao, C. Theriot, 2018, Anaerobe.

PIR-B Regulates CD4+ IL17a+ T-Cell Survival and Restricts T-Cell–Dependent Intestinal Inflammatory Responses

P. King, P. Foster, K. Hoebe, 2021, Cellular and molecular gastroenterology and hepatology.

The effect of CT26 tumor-derived TGF-β on the balance of tumor growth and immunity.

J. Kao, H. Grasberger, Min F Zhang, 2017, Immunology letters.

Expression of a Soluble TGF-β Receptor by Tumor Cells Enhances Dendritic Cell/Tumor Fusion Vaccine Efficacy1

J. Kao, Min F Zhang, Jian-Jun Chen, 2008, The Journal of Immunology.

Superior efficacy of dendritic cell-tumor fusion vaccine compared with tumor lysate-pulsed dendritic cell vaccine in colon cancer.

Min Zhang, J. Kao, Chuan-min Chen, 2005, Immunology letters.

Tumor-Derived TGF-β Reduces the Efficacy of Dendritic Cell/Tumor Fusion Vaccine1

Y. Gong, J. Kao, Qiong-duan Zheng, 2003, The Journal of Immunology.

CD4+ tissue-resident memory T-cells expand and are a major source of mucosal tumor necrosis factor α in active Crohn's Disease.

P. Higgins, W. Zou, J. Kao, 2019, Journal of Crohn's & colitis.

Association of adiponectin multimers with Barrett’s oesophagus

N. Shaheen, J. Rubenstein, J. Donovan, 2009, Gut.

Functional Characterization of Inflammatory Bowel Disease–Associated Gut Dysbiosis in Gnotobiotic Mice

P. Higgins, A. Hirayama, V. Young, 2016, Cellular and molecular gastroenterology and hepatology.

Expression of Fas ligand is not a main mechanism used by tumors to counteract antitumor immunity.

J. Kao, Wenying Song, Qiong-duan Zheng, 2004, Frontiers in bioscience : a journal and virtual library.

Microbial ecology of the murine gut associated with the development of dextran sodium sulfate‐induced colitis

V. Young, J. Kao, N. Nagalingam, 2011, Inflammatory bowel diseases.

Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria.

J. Merchant, J. Kao, D. Gumucio, 2010, Gastroenterology.

Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways

M. Tremelling, M. Parkes, H. Drummond, 2008, PLoS medicine.

Eosinophilic esophagitis: update on management and controversies

J. Kao, Joan W Chen, Joan W. Chen, 2017, British Medical Journal.

Mucolytic bacteria license pathobionts to acquire host-derived nutrients during dietary nutrient restriction

T. Schmidt, N. Barnich, C. Alteri, 2022, bioRxiv.

Peptic Ulcer Diseases: Genetics, Mechanism, and Therapies

Deng-Chyang Wu, Hidekazu Suzuki, J. Kao, 2014, BioMed research international.

Treatment of Helicobacter gastritis with IL-4 requires somatostatin

Malcolm J. Low, John Y. Kao, M. Low, 2003, Proceedings of the National Academy of Sciences of the United States of America.

A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture

P. Higgins, J. Colacino, J. Kao, 2018, Cellular and molecular gastroenterology and hepatology.

Fecal Microbiota Transplant for Treatment of Clostridium difficile Infection in Immunocompromised Patients

M. Mellow, T. Borody, L. Brandt, 2014, The American Journal of Gastroenterology.

Depression, antidepressant medications, and risk of Clostridium difficile infection

K. Langa, S. Saint, D. Aronoff, 2013, BMC Medicine.

Recent advances in pediatric celiac disease

J. Kao, Grace J Lee, 2017, Expert review of gastroenterology & hepatology.

Helicobacter pylori eradication with bismuth quadruple therapy leads to dysbiosis of gut microbiota with an increased relative abundance of Proteobacteria and decreased relative abundances of Bacteroidetes and Actinobacteria

Deng-Chyang Wu, Chao-Yu Pan, J. Kao, 2018, Helicobacter.

Murine Colitis is Mediated by Vimentin

Yue Yu, M. Swanson, Marta J. Gonzalez-Hernandez, 2013, Scientific Reports.

Detection of colonic inflammation with Fourier transform infrared spectroscopy using a flexible silver halide fiber

Thomas D. Wang, Rolf Wolters, Sharon J. Miller, 2010, Biomedical optics express.

Effects of Anti-Helicobacter pylori Therapy on Incidence of Autoimmune Diseases, Including Inflammatory Bowel Diseases.

Deng-Chyang Wu, A. Waljee, J. Kao, 2019, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Intestinal dysbiosis in inflammatory bowel disease

J. Kao, Chun-Chia Chen, N. Kaur, 2011, Gut microbes.

Houston Consensus Conference on Testing for Helicobacter pylori Infection in the United States

D. Graham, H. El‐Serag, S. Moss, 2018, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Increased risk for inflammatory bowel disease in congenital hypothyroidism supports the existence of a shared susceptibility factor

A. Waljee, J. Kao, J. Adler, 2018, Scientific Reports.

Outcomes of furazolidone- and amoxicillin-based quadruple therapy for Helicobacter pylori infection and predictors of failed eradication

J. Kao, Weiling Hu, Wenfang Zheng, 2018, World journal of gastroenterology.

Helicobacter pylori‐Pulsed Dendritic Cells Induce H. pylori‐Specific Immunity in Mice

J. Kao, Sivaprakash Rathinavelu, K. Eaton, 2008, Helicobacter.

Equivalent efficacies of reverse hybrid and concomitant therapies in first‐line treatment of Helicobacter pylori infection

Deng-Chyang Wu, J. Kao, C. Kuo, 2020 .

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.

U. Sauer, A. Kaser, P. Rosenstiel, 2023, Immunity.

IL-10 produced by macrophages regulates epithelial integrity in the small intestine

K. Honda, K. Atarashi, A. Nusrat, 2019, Scientific Reports.

Anti-inflammatory activity of bone morphogenetic protein signaling pathways in stomachs of mice.

Min Zhang, Maria Mao, D. Dang, 2014, Gastroenterology.

Inter-individual Recovery of the Microbiota and Metabolome Over Time Following Fecal Microbiota Transplantation in Patients with Recurrent Clostridium difficile Infection

V. Young, J. Kao, C. Theriot, 2017, bioRxiv.

Short‐term and long‐term impacts of Helicobacter pylori eradication with reverse hybrid therapy on the gut microbiota

Deng-Chyang Wu, Chao-Yu Pan, J. Kao, 2019, Journal of gastroenterology and hepatology.

Butyrate increases IL-23 production by stimulated dendritic cells.

Min Zhang, J. Merchant, G. Huffnagle, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Early timing of single balloon enteroscopy is associated with increased diagnostic yield in patients with overt small bowel bleeding.

Hsiu‐Po Wang, Han-Mo Chiu, Yi-Chia Lee, 2019, Journal of the Formosan Medical Association = Taiwan yi zhi.

How can individuals and the GI community reduce climate change?

John A. Williams, J. Kao, M. Omary, 2019, Gastroenterology.

The efficacy of culture‐guided versus empirical therapy with high‐dose proton pump inhibitor as third‐line treatment of Helicobacter pylori infection: A real‐world clinical experience

Deng-Chyang Wu, J. Kao, Jiunn-Wei Wang, 2022, Journal of gastroenterology and hepatology.

Tetracycline‐levofloxacin versus amoxicillin‐levofloxacin quadruple therapies in the second‐line treatment of Helicobacter pylori infection

Deng-Chyang Wu, J. Kao, S. Chuah, 2021, Helicobacter.

Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

P. Higgins, R. Jenq, N. Karlsson, 2020, Nature Medicine.

Editorial Peptic Ulcer Diseases: Genetics, Mechanism, and Therapies

Deng-Chyang Wu, Hidekazu Suzuki, J. Kao, 2014 .

Probiotic-Mediated Protection Against Chronic Water-Avoidance Stress Enteritis in Mice is Associated with Lamina Propria Plasmacytoid Dendritic Cell Infiltration

J. Kao, H. Grasberger, Yundong Sun, 2017 .

Helicobacter pylori Antimicrobial Susceptibility Testing-Guided Salvage Therapy in the USA: A Real Life Experience

J. Kao, S. Bishu, H. Grasberger, 2018, Digestive Diseases and Sciences.

Equivalent Efficacies of Reverse Hybrid and Bismuth Quadruple Therapies in Eradication of Helicobacter pylori Infection in a Randomized Controlled Trial

D. Graham, Deng-Chyang Wu, J. Kao, 2018, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Helicobacter pylori DNA's anti-inflammatory effect on experimental colitis

Min Zhang, J. Kao, S. Owyang, 2012, Gut microbes.

Helicobacter pylori: beneficial for most?

J. Kao, S. Owyang, Jay Luther, 2011, Expert review of gastroenterology & hepatology.

Dendritic cell‐derived TGF‐β mediates the induction of mucosal regulatory T‐cell response to Helicobacter infection essential for maintenance of immune tolerance in mice

J. Kao, Min Zhang, S. Bishu, 2020, Helicobacter.

IL-15 promotes inflammatory Th17 cells in the intestine

J. Nemzek, J. Kao, S. Bishu, 2023, bioRxiv.

Packaging and Waste in the Endoscopy Suite

J. Kao, Silvio W. de MeloJr, Gordon L. Taylor, 2021, Techniques and Innovations in Gastrointestinal Endoscopy.

Citrobacter rodentium Induces Tissue-Resident Memory CD4+ T Cells

P. Higgins, W. Zou, J. Kao, 2019, Infection and Immunity.

Validation of Pharyngeal Acid Reflux Episodes Using Hypopharyngeal Multichannel Intraluminal Impedance-pH

Yung-An Tsou, Chi-Sen Chang, Jachih Fu, 2023, Journal of neurogastroenterology and motility.

Tumor-derived TGF-beta reduces the efficacy of dendritic cell/tumor fusion vaccine.

Y. Gong, J. Kao, Qiong-duan Zheng, 2001, Journal of immunology.

A Pilot Study of the Association of Low Plasma Adiponectin and Barrett's Esophagus

H. Morgenstern, L. McMahon, J. Rubenstein, 2008, The American Journal of Gastroenterology.

Anaplastic Lymphoma Masquerading as Sclerosing Mesenteritis: A Case Report

J. Kao, M. Al-Hawary, Alexander J. Faje, 2012, Journal of Gastrointestinal Cancer.

Hybrid, High-Dose Dual and Bismuth Quadruple Therapies for First-Line Treatment of Helicobacter pylori Infection in Taiwan: A Multicenter, Open-Label, Randomized Trial

Deng-Chyang Wu, J. Kao, S. Chuah, 2023, The American journal of gastroenterology.

Increased risk for inflammatory bowel disease in congenital hypothyroidism supports the existence of a shared susceptibility factor

A. Waljee, J. Kao, J. Adler, 2018, Scientific Reports.

Does stress induce bowel dysfunction?

J. Kao, Yu-Ming Chang, M. El-zaatari, 2014, Expert review of gastroenterology & hepatology.

Alternative eradication regimens for Helicobacter pylori infection in Indonesian regions with high metronidazole and levofloxacin resistance

Youming Li, Y. Yamaoka, Juntaro Matsuzaki, 2019, Infection and drug resistance.

Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice.

Mark J. Miller, Min Zhang, J. Mills, 2010, Gastroenterology.

Anti-inflammatory activity of bone morphogenetic protein signaling pathways in stomachs of mice.

D. Dang, A. Todisco, J. Kao, 2014, Gastroenterology.

Helicobacter pylori‐Pulsed Dendritic Cells Induce H. pylori‐Specific Immunity in Mice

J. Kao, Sivaprakash Rathinavelu, K. Eaton, 2008, Helicobacter.

Principles of Mucosal Immunology

J. Kao, 2013 .

Equivalent efficacies of reverse hybrid and concomitant therapies in first‐line treatment of Helicobacter pylori infection

Deng-Chyang Wu, J. Kao, C. Kuo, 2020, Journal of gastroenterology and hepatology.