F. Housseau

发表

Microbiota organization is a distinct feature of proximal colorectal cancers

K. Kinzler, B. Vogelstein, S. Peterson, 2014, Proceedings of the National Academy of Sciences.

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Ludmila V. Danilova, L. Cope, A. Zaheer, 2017, Science.

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

J. Elisseeff, Hao Wang, D. Pardoll, 2016, Science.

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

Cynthia L Sears, Shaoguang Wu, Drew M Pardoll, 2009, Nature Medicine.

The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity

Ludmila V. Danilova, L. Cope, V. Velculescu, 2018, Cancer Immunology Research.

Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non–Small Cell Lung Cancer

David R. Jones, V. Velculescu, J. Taube, 2019, Clinical Cancer Research.

Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy

L. Diaz, E. Jaffee, D. Pardoll, 2019, Cancer Immunology Research.

The Scaffold Immune Microenvironment: Biomaterial-Mediated Immune Polarization in Traumatic and Nontraumatic Applications.

J. Elisseeff, D. Pardoll, F. Housseau, 2016, Tissue engineering. Part A.

17beta-estradiol alters the activity of conventional and IFN-producing killer dendritic cells.

A. Scott, S. Klein, F. Housseau, 2008, Journal of immunology.

Tumor‐specific CD8+ T lymphocytes derived from the peripheral blood of prostate cancer patients by in vitro stimulation with autologous tumor cell lines

D. Pardoll, S. Topalian, F. Housseau, 2002, International journal of cancer.

N‐linked carbohydrates in tyrosinase are required for its recognition by human MHC class II‐restricted CD4+ T cells

M. Gonzales, S. Topalian, P. Robbins, 2001, European journal of immunology.

Interleukin-17 and type 17 helper T cells in cancer management and research

Nicolas Llosa, F. Housseau, A. Geis, 2014, ImmunoTargets and therapy.

IFN-producing killer dendritic cells are antigen-presenting cells endowed with T-cell cross-priming capacity.

D. Pardoll, F. Housseau, Jang-June Park, 2009, Cancer research.

Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits Regenerative Response

Alexis N. Peña, J. Elisseeff, E. Fertig, 2021, bioRxiv.

Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors

J. Taube, L. Diaz, D. Pardoll, 2019, Clinical Cancer Research.

Interferon-producing killer dendritic cells (IKDC)

F. Housseau, 2010 .

CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells.

P. Hwu, F. Housseau, J. Thibodeau, 2003, Cancer research.

CD 40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells 1

P. Hwu, F. Housseau, J. Thibodeau, 2003 .

In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses

Lieping Chen, D. Pardoll, R. Schulick, 2005, The Journal of experimental medicine.

Cooperative B7-1/2 (CD80/CD86) and B7-DC Costimulation of CD4+ T Cells Independent of the PD-1 Receptor

Lieping Chen, D. Pardoll, J. Powell, 2003, The Journal of experimental medicine.

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

K. Kinzler, B. Vogelstein, J. Taube, 2015, Journal of Immunotherapy for Cancer.

Quantitative real-time RT-PCR as a method for monitoring T lymphocyte reactivity to full-length tyrosinase protein in vaccinated melanoma patients.

M. Gonzales, S. Topalian, B. Roberts, 2002, Journal of immunological methods.

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

G. Milligan, W. Dalton, D. Huso, 2021, Communications biology.

Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice.

C. Sears, F. Housseau, H. Fan, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics?

H. Ashktorab, F. Housseau, H. Brim, 2022, World journal of gastroenterology.

Type 2 immunity induced by bladder extracellular matrix enhances corneal wound healing

J. Elisseeff, M. Stepp, Xiaokun Wang, 2021, Science Advances.

Interleukin-17 and senescence regulate the foreign body response

Gedge D. Rosson, J. Elisseeff, D. Pardoll, 2019, bioRxiv.

Recognition of a shared human prostate cancer-associated antigen by nonclassical MHC-restricted CD8+ T cells.

R. K. Bright, M. Nishimura, S. Topalian, 1999, Journal of immunology.

T Cells + MHC-Restricted CD8 Cancer-Associated Antigen by Nonclassical Recognition of a Shared Human Prostate

R. K. Bright, S. Topalian, F. Housseau, 1999 .

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

D. Pardoll, D. Huso, C. Sears, 2018, Cell host & microbe.

MHC‐dependent cytolysis of autologous tumor cells by lymphocytes infiltrating urothelial carcinomas

V. Paradis, S. Richon, J. Bidart, 1997, International journal of cancer.

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.

D. Pardoll, D. Huso, J. Vadivelu, 2016, Cancer research.

IKDCs or B220+ NK cells are pre-mNK cells.

L. Zitvogel, F. Housseau, 2012, Blood.

Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia.

A. Maitra, S. Leach, E. Jaffee, 2014, Cancer cell.

Helminth egg derivatives as proregenerative immunotherapies

Alexis N. Peña, D. Zack, J. Elisseeff, 2022, bioRxiv.

Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors

J. Chaft, D. Pardoll, J. Gills, 2022, Cancer Immunology, Immunotherapy.

Enterotoxigenic Bacteroides fragilis (ETBF)-mediated colitis in Min (Apc+/-) mice: a human commensal-based murine model of colon carcinogenesis

C. Sears, F. Housseau, 2010, Cell cycle.

Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy.

S. Baylin, J. Hicks, A. D. De Marzo, 2021, Cancer discovery.

Immune checkpoint blockade in microsatellite instable colorectal cancers: Back to the clinic

F. Housseau, Nicolas J. Llosa, 2015, Oncoimmunology.

IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis.

Alexis N. Peña, J. Elisseeff, D. Pardoll, 2020, The Journal of clinical investigation.

Procarcinogenic regulatory T cells in microbial-induced colon cancer

F. Housseau, A. Geis, 2016, Oncoimmunology.

Immune checkpoints expression in MSI versus MSS colorectal cancers and their potential therapeutic implications.

D. Pardoll, C. Sears, E. Wick, 2014 .

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

K. Kinzler, B. Vogelstein, J. Taube, 2015, Journal of Immunotherapy for Cancer.

Host responses to mucosal biofilms in the lung and gut

Julia L. Drewes, C. Merlo, C. Sears, 2020, Mucosal Immunology.

Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes

C. Pratilas, D. Pardoll, C. Meyer, 2021, Journal for ImmunoTherapy of Cancer.

Divergent immune responses to synthetic and biological scaffolds.

J. Elisseeff, D. Pardoll, Matthew T. Wolf, 2019, Biomaterials.

Free hCGβ and Nongonadal Neoplasms

J. Bidart, P. Cottu, F. Housseau, 1994 .

Deficient antigen processing of a protein quaternary structure can be overcome by receptor‐mediated uptake

J. Bidart, N. Rouas-Freiss, J. Guillet, 1993, European journal of immunology.

Influence of protein-quaternary structure on antigen processing.

J. Bidart, J. Guillet, F. Housseau, 1993, Journal of immunology.

Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans

J. Elisseeff, D. Pardoll, Xiaokun Wang, 2020, Science Translational Medicine.

Interleukin-36γ–producing macrophages drive IL-17–mediated fibrosis

P. Cahan, J. Taube, J. Elisseeff, 2019, Science Immunology.

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

D. Pardoll, D. Huso, C. Sears, 2018, Cell host & microbe.

Microbiota and Immune Responses in Colon Cancer: More to Learn

C. Sears, F. Housseau, F. McAllister, 2014, Cancer journal.

Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis.

D. Pardoll, D. Huso, C. Sears, 2015, Cancer discovery.

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Ludmila V. Danilova, L. Cope, K. Kinzler, 2019, Journal of Immunotherapy for Cancer.

Microbiota, mucosal immunity, and Colon cancer

Julia L. Drewes, F. Housseau, J. Domingue, 2020 .

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic

Julia L. Drewes, A. Fodor, J. White, 2019, The Journal of clinical investigation.

Roles for Interleukin 17 and Adaptive Immunity in Pathogenesis of Colorectal Cancer.

C. Sears, F. Wan, F. Housseau, 2018, Gastroenterology.

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

Drew M. Pardoll, Cynthia L. Sears, Robert A. Anders, 2018, Science.

The Myeloid Immune Signature of Enterotoxigenic Bacteroides Fragilis-Induced Murine Colon Tumorigenesis

D. Pardoll, C. Sears, F. Housseau, 2016, Mucosal Immunology.

Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy

Cynthia L Sears, Julia L. Drewes, C. Sears, 2016, British Journal of Cancer.

Epigenetic therapy inhibits metastases by disrupting premetastatic niches

C. Zahnow, J. Margolick, S. Baylin, 2020, Nature.

The ‘kiss of death’ by dendritic cells to cancer cells

C. Chan, F. Housseau, C. Chan, 2008, Cell Death and Differentiation.

Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity

L. Lanier, D. Pardoll, M. Stins, 2006, Nature Medicine.

Gutting it Out: Developing Effective Immunotherapies for Patients With Colorectal Cancer.

J. Galon, M. Lotze, F. Housseau, 2021, Journal of immunotherapy.

A Blueprint to Advance Colorectal Cancer Immunotherapies

Vanessa M. Hubbard-Lucey, L. Diaz, E. Jaffee, 2017, Cancer Immunology Research.

Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models

Julia L. Drewes, J. White, S. Verbridge, 2022, mBio.

Key players in the immune response to biomaterial scaffolds for regenerative medicine

Jennifer H Elisseeff, J. Elisseeff, F. Housseau, 2017, Advanced drug delivery reviews.

Antigen-presenting function of murine gonadal epithelial cell lines.

J. Bidart, N. Rouas-Freiss, J. Guillet, 1997, Cellular immunology.

Transfer learning of an in vivo-derived senescence signature identifies conserved and tissue-specific senescence across species and diverse pathologies

Alexis N. Peña, J. Elisseeff, E. Fertig, 2022, bioRxiv.

Stat3 Activation in Murine Colitis Induced by Enterotoxigenic Bacteroides fragilis

D. Pardoll, D. Huso, C. Sears, 2014, Inflammatory bowel diseases.

Bacteroides fragilis subverts mucosal biology: from symbiont to colon carcinogenesis.

C. Sears, F. Housseau, A. Geis, 2014, The Journal of clinical investigation.

Cutting Edge: An In Vivo Requirement for STAT3 Signaling in TH17 Development and TH17-Dependent Autoimmunity1

Hua Yu, Drew M. Pardoll, Charles G. Drake, 2007, The Journal of Immunology.

Single cell RNA-seq in regenerative and fibrotic biomaterial environments defines new macrophage subsets

P. Cahan, J. Taube, J. Elisseeff, 2019, bioRxiv.

Multiplexed analysis of fixed tissue RNA using Ligation in situ Hybridization

Erick R. Scott, W. Timp, J. Credle, 2017, Nucleic acids research.

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

Cody N. Heiser, Julia L. Drewes, R. Coffey, 2022, Cancer discovery.

Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic Bacteroides fragilis, in Wild-Type C57BL/6 Mice

D. Golenbock, A. Franco, D. Huso, 2009, Infection and Immunity.

Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A

D. Pardoll, C. Sears, F. Housseau, 2018, Mucosal Immunology.

Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment.

Hao Wang, Cynthia L Sears, H. O’Hagan, 2016, The Journal of infectious diseases.

Enterotoxigenic Bacteroides fragilis induces oncogenic regulatory T cells (TUM9P.1000)

D. Pardoll, D. Huso, C. Sears, 2015, Journal of Immunology.

[Evans' syndrome caused by D-penicillamine in rheumatoid arthritis. Value of the corticoids-danazol combination].

N. Ifrah, V. Berton, F. Housseau, 1991, Revue du rhumatisme et des maladies osteo-articulaires.

538 Comprehensive single cell transcriptomic profiling of untreated resectable lung cancers

V. Anagnostou, K. Sanber, F. Housseau, 2022, Regular and Young Investigator Award Abstracts.

Erratum: Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells (Cell Host & Microbe (2018) 23(2) (203–214.e5) (S1931312818300428) (10.1016/j.chom.2018.01.007))

D. Pardoll, D. Huso, C. Sears, 2018 .

Lung Cancer Recurrence Risk Prediction through Integrated Deep Learning Evaluation

A. Rahmim, K. Pienta, Rongkai Yan, 2022, Cancers.

Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies

J. Elisseeff, E. Fertig, D. Pardoll, 2023, GeroScience.

J. Elisseeff, E. Fertig, D. Pardoll, 2021 .

Integrating Tissue Microenvironment with Scaffold Design to Promote Immune-Mediated Regeneration

J. Elisseeff, D. Pardoll, F. Housseau, 2015 .