R. Pon

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A shared core microbiome in soda lakes separated by large distances

M. Strous, P. Gordon, Christine Sharp, 2019, bioRxiv.

A shared core microbiome in soda lakes separated by large distances

M. Strous, P. Gordon, Christine Sharp, 2019, Nature Communications.

1 Chemical Synthesis of Oligonucleotides: From Dream to Automation

R. Pon, 2003 .

A long chain biotin phosphoramidite reagent for the automated synthesis of 5′-biotinylated oligonucleotides

R. Pon, 1991 .

The chemical synthesis of oligoribonucleotides. IX. A comparison of protecting groups in the dichloridite procedure

J. Seifert, R. Pon, M. Nemer, 1980 .

Molecular recognition between oligopeptides and nucleic acids. Specificity of binding of a monocationic bis‐furan lexitropsin to DNA deduced from footprinting and 1H NMR studies

J. Lown,, R. Pon, R. G. Shea, 1989, Journal of molecular recognition : JMR.

Molecular recognition between oligopeptides and nucleic acids. Sequence specific binding of (4S)‐(+)‐ and (4R)‐(−)‐dihydrokikumycin B to DNA deduced form 1H NMR, footprinting studies and thermodynamic data

K. Breslauer, J. Lown,, J. Hartley, 1989, Journal of molecular recognition : JMR.

Sequence specific molecular recognition and binding of a monocationic bis-imidazole lexitropsin to the decadeoxyribonucleotide d-[(GATCCGTATG).(CATACGGATC)]: structural and dynamic aspects of intermolecular exchange studied by 1H-NMR.

D. Coulter, J. Lown,, R. Pon, 1988, Journal of biomolecular structure & dynamics.

Structural and dynamic aspects of binding of a prototype lexitropsin to the decadeoxyribonucleotide d(CGCAATTGCG)2 deduced from high-resolution 1H NMR Studies.

J. Lown,, J. Hartley, D. Chang, 1988, Biochemistry.

Structural and dynamic aspects of the sequence specific binding of netropsin and its bis-imidazole analogue on the decadeoxyribonucleotide d-[CGCAATTGCG]2.

J. Lown,, R. Pon, M. Lee, 1988, Journal of biomolecular structure & dynamics.

Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.

K. Gehring, A. Noronha, C. Wilds, 2001, Nucleic acids research.

PROPERTIES OF ARABINONUCLEIC ACIDS (ANA & 20′F-ANA): IMPLICATIONS FOR THE DESIGN OF ANTISENSE THERAPEUTICS THAT INVOKE RNASE H CLEAVAGE OF RNA

K. Gehring, A. Noronha, C. Wilds, 2001, Nucleosides, nucleotides & nucleic acids.

CHARACTERIZATION OF A CPI-LEXITROPSIN CONJUGATE-OLIGONUCLEOTIDE COVALENT COMPLEX BY 1H NMR AND RESTRAINED MOLECULAR DYNAMICS SIMULATION

J. Lown,, Yuqiang Wang, R. Pon, 1995 .

Inhibition of cell adhesion to plastic substratum by phosphorothioate oligonucleotide.

P. Watson, R. Pon, R. Shiu, 1992, Experimental cell research.

A general method for the purification of synthetic oligodeoxyribonucleotides containing strong secondary structure by reversed-phase high-performance liquid chromatography on PRP-1 resin.

J. Van De Sande, R. Pon, M. Germann, 1987, Analytical biochemistry.

Properties of Arabinonucleic Acids (ANA & 20′F‐ANA): Implications for the Design of Antisense Therapeutics That Invoke RNase H Cleavage of RNA

A. Denisov, K. Gehring, A. Noronha, 2001 .

Primer-mediated enzymatic amplification of cytomegalovirus (CMV) DNA. Application to the early diagnosis of CMV infection in marrow transplant recipients.

Richard, James, M. Naylor, 1989, Journal of Clinical Investigation.

Increased efficiency of the Taq polymerase catalyzed polymerase chain reaction.

R. Pon, S. Krawetz, G. Dixon, 1989, Nucleic acids research.

Rapid automated derivatization of solid-phase supports for oligonucleotide synthesis using uronium or phosphonium coupling reagents

R. Pon, Shuyuan Yu, 1997 .

High Resolution 2D-NMR Studies Including Complete Assignments and Conformational Characteristics of the NF-κB Binding Enhancer Element of HIV-LTR

J. Lown,, R. Pon, N. Fregeau, 1995 .

Sequence specific molecular recognition and binding by a GC recognizing Hoechst 33258 analogue to the decadeoxyribonucleotide d-[CATGGCCATG]2: structural and dynamic aspects deduced from high field 1H-NMR studies.

S. Kumar, J. Lown,, J. Zimmermann, 1990, Journal of biomolecular structure & dynamics.

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

Colin A. Johnson, Teunis J. P. van Dam, J. Shendure, 2015, Nature Cell Biology.

Gemcitabine (2',2'-difluoro-2'-deoxycytidine), an antimetabolite that poisons topoisomerase I.

Y. Pommier, W. Gmeiner, F. Goldwasser, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Molecular recognition between oligopeptides and nucleic acids: sequence-specific binding of the naturally occurring antibiotic (4S)-(+)-anthelvencin A and its (4R)-(-) enantiomer to deoxyribonucleic acids deduced from proton NMR, footprinting, and thermodynamic data

K. Breslauer, J. Lown,, J. Hartley, 1989 .

Molecular recognition between oligopeptides and nucleic acids: influence of van der Waals contacts in determining the 3'-terminus of DNA sequences read by monocationic lexitropsins

J. Lown,, J. Hartley, R. Pon, 1988 .

Rapid DNA fingerprinting to control for specimen errors in HIV testing by the polymerase chain reaction.

R. Pon, S. Cassol, S. Read, 1992, Molecular and cellular probes.

Molecular Recognition Between Oligopeptides and Nucleic Acids: Sequence-Specific Binding of the Naturally Occurring Antibiotic (4S)-(+)-Anthelvencin A and Its (4R)-(-) Enantiomer to Deoxyribonucleic Acids Deduced from 1H NMR, Footprin

K. Breslauer, J. Lown,, J. Hartley, 1989 .

Chromosomal localization and structure of the human P1 protamine gene.

J. Hamerton, R. Pon, S. Krawetz, 1989, Genomics.

Preparation of Oligomeric 2′-Deoxy-5-Fluorouridylate of Defined Length and Backbone Composition: A Novel Pro-Drug form of the Potent Anti-Cancer Drug 2′-Deoxy-5-Fluorouridylate

P. Iversen, W. Gmeiner, R. Pon, 1995 .

Synthesis of 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-5-fluorouridine 3'-(Cyanoethyl N,N-diisopropylphosphoramidite) and Its Use in the Synthesis of RNA

W. Gmeiner, R. Pon, P. Sahasrabudhe, 1994 .

Tandem oligonucleotide synthesis using linker phosphoramidites

R. Pon, Shuyuan Yu, 2005, Nucleic acids research.

Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer.

P. Watson, R. Pon, R. Shiu, 1991, Cancer research.

Cytotoxicity and in-vivo tolerance of FdUMP[10]: a novel pro-drug of the TS inhibitory nucleotide FdUMP.

W. Gmeiner, R. Pon, A. Skradis, 1999, Nucleosides & nucleotides.

Growth of Human Breast Cancer in the myc Oligonucleotide Identifies a Critical Role for c-Expression by Phosphorothioate Antisense myc Inhibition of c-Updated

P. Watson, R. Pon, R. Shiu, 2006 .

NMR solution structure of an oligonucleotide hairpin with a 2'F-ANA/RNA stem: implications for RNase H specificity toward DNA/RNA hybrid duplexes.

K. Gehring, C. Wilds, J. Trempe, 2001, Journal of the American Chemical Society.

Analysis of functional domains on reovirus cell attachment protein sigma 1 using cloned S1 gene deletion mutants.

P. C. Lee, R. Pon, S. Masri, 1987, Virology.

Enhanced coupling efficiency using 4-dimethylaminopyridine (DMAP) and either tetrazole, 5-(o-nitrophenyl) tetrazole, or 5-(p-nitrophenyl) tetrazole in the solid phase synthesis of oligoribonucleotides by the phosphoramidite procedure.

R. Pon, 1987 .

Solid‐Phase Supports for Oligonucleotide Synthesis

R. Pon, 2000, Current protocols in nucleic acid chemistry.

Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein.

J. Strong, P. C. Lee, R. Duncan, 1991, Virology.

Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives.

N. Usman, M. Damha, R. Pon, 1986, Nucleic acids research.

Characterization of a parallel-stranded DNA hairpin.

H. Vogel, J. Van De Sande, R. Pon, 1989, Biochemistry.

Length-dependent formation of parallel-stranded DNA in alternating AT segments.

J. Van De Sande, R. Pon, M. Germann, 1990, Biochemistry.

Isohelicity and Strand Selectivity in the Minor Groove Binding of Chiral (1R,2R)- and (1S,2S)-Bis(netropsin)-1,2-cyclopropanedicarboxamide Ligands to Duplex DNA

J. Lown,, R. Pon, G. C. Hill, 1994 .

Necessary protection of the O6-position of guanine during the solid phase synthesis of oligonucleotides by the phosphoramidite approach

M. Damha, R. Pon, K. K. Ogilvie, 1985 .

Linker phosphoramidite reagents for the attachment of the first nucleoside to underivatized solid-phase supports.

R. Pon, Shuyuan Yu, 2004, Nucleic acids research.

Effects ofsite-specific substitution of5-fluorouridine on thestabilities ofduplex DNAandRNA

R. Pon, P. Sahasrabudhe, H. Gmeiner, 1995 .

Parallel stranded DNA.

J. Van De Sande, E. von Kitzing, T. Jovin, 1988, Science.

Multiple oligodeoxyribonucleotide syntheseson a reusable solid-phase CPG support via the hydroquinone-O,O'-diacetic acid (Q-Linker) linker arm.

R. Pon, Y. Sanghvi, Z. Guo, 1999, Nucleic acids research.

Hydroquinone-O,O'-diacetic acid ('Q-linker') as a replacement for succinyl and oxalyl linker arms in solid phase oligonucleotide synthesis.

R. Pon, Shuyuan Yu, S. Yu, 1997, Nucleic acids research.

Prevention of chain cleavage in the chemical synthesis of 2'-silylated oligoribonucleotides.

R. Pon, K. K. Ogilvie, T. Wu, 1989, Nucleic acids research.

Structural and dynamic aspects of non-intercalative (1:1) binding of a thiazole-lexitropsin to the decadeoxyribonucleotide d-[CGCAATTGCG]2: An 1H-NMR and molecular modeling study.

T. Joseph, S. Kumar, Y. Bathini, 1991, Journal of biomolecular structure & dynamics.

Studies on cooperative binding of an extended distamycin A analogue in the minor groove of DNA by NMR spectroscopy.

J. Lown,, R. Pon, Y. Yang, 1996, Biochemical and biophysical research communications.

Preparation of ribonucleoside 3′-O-phosphoramidites and their application to the automated solid phase synthesis of oligonucleotides

N. Usman, R. Pon, K. K. Ogilvie, 1985 .

Chemical synthesis of branched RNA: novel trinucleoside diphosphates containing vicinal 2′–5′ and 3′–5′ phosphodiester linkages

M. Damha, R. Pon, K. K. Ogilvie, 1985 .

Automated oligoribonucleotide synthesis on silica gel supports

R. Pon, K. K. Ogilvie, 1984 .

Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides.

M. Damha, R. Pon, K. K. Ogilvie, 1985, Nucleic acids research.

N-Phenoxyacetylated guanosine and adenosine phosphoramidites in the solid phase synthesis of oligoribonucleotides: Synthesis of a ribozyme sequence

R. Pon, Taifeng Wu, K. Kelvin, 1988 .

Automated Solid Phase Synthesis of Oligoribonucleotides. The Synthesis of a tRNA Anticodon Loop from Nucleoside-3'-chlorophosphite Derivatives.

R. Pon, K. K. Ogilvie, 1984 .

Rapid esterification of nucleosides to solid-phase supports for oligonucleotide synthesis using uronium and phosphonium coupling reagents.

R. Pon, Y. Sanghvi, S. Yu, 1999, Bioconjugate chemistry.

Simultaneous analysis of nucleosides and nucleotides by high-performance liquid chromatography

R. Pon, K. K. Ogilvie, 1981 .

Reusable Solid-Phase Supports for Oligonucleotide Synthesis Using Hydroquinone-O,O'-diacetic Acid (“Q-Linker”)

Zhiqian Guo, R. Pon, Y. Sanghvi, 1999 .

Hydroquinone-O,O′-diacetic acid as a more labile replacement for succinic acid linkers in solid-phase oligonucleotide synthesis

R. Pon, Shuyuan Yu, 1997 .

Developments in the chemical synthesis of naturally occurring DNA and RNA sequences with normal and unusual linkages

N. Usman, M. Damha, R. Pon, 1987 .

Nucleoside Phosphoramidites Containing Cleavable Linkers

R. Pon, 2005, Current protocols in nucleic acid chemistry.

Solid-phase supports for oligonucleotide synthesis.

R. Pon, 1994, Methods in molecular biology.

Derivatization of controlled pore glass beads for solid phase oligonucleotide synthesis.

R. Pon, K. K. Ogilvie, N. Usman, 1988, BioTechniques.

Attachment of Nucleosides to Solid‐Phase Supports

R. Pon, 2000, Current protocols in nucleic acid chemistry.

LARGE-SCALE SYNTHESIS OF “Cpep” RNA MONOMERS AND THEIR APPLICATION IN AUTOMATED RNA SYNTHESIS

R. Pon, Y. Sanghvi, S. Yu, 2005, Nucleosides, nucleotides & nucleic acids.

Developments in the Chemical Synthesis of Naturally Occurring DNA and RNA Sequences with Normal and Unusual Linkages.

N. Usman, M. Damha, R. Pon, 1987 .

Attachment of Nucleosides and Other Linkers to Solid‐Phase Supports for Oligonucleotide Synthesis

R. Pon, A. Guzaev, 2013, Current protocols in nucleic acid chemistry.

Linker phosphoramidite reagents for oligonucleotide synthesis on underivatized solid-phase supports

R. Pon, Shuyuan Yu, 2001 .

Structural Basis for Topoisomerase I Inhibition by Nucleoside Analogs

Y. Pommier, W. Gmeiner, P. Pourquier, 2003, Nucleosides, nucleotides & nucleic acids.

Solution structures of 5-fluorouracil-substituted DNA and RNA decamer duplexes.

W. Gmeiner, R. Pon, P. Sahasrabudhe, 1996, Biochemistry.

Effects of site-specific substitution of 5-fluorouridine on the stabilities of duplex DNA and RNA.

W. Gmeiner, R. Pon, P. Sahasrabudhe, 1995, Nucleic Acids Research.

DNA Duplexes Containing Alpha Anomeric Nucleotides and Polarity Reversals: Coexistence of Parallel and Antiparallel DNA

J. Aramini, R. Pon, B. Kalisch, 1997 .

MULTIPLE OLIGONUCLEOTIDE SYNTHESIS IN TANDEM ON SOLID-PHASE SUPPORTS FOR SMALL AND LARGE SCALE SYNTHESIS

R. Pon, Y. Sanghvi, S. Yu, 2001, Nucleosides, Nucleotides & Nucleic Acids.

Cytarabine-induced destabilization of a model Okazaki fragment.

W. Gmeiner, R. Pon, A. Skradis, 1998, Nucleic acids research.

Developmnet of an efficient oligonucleotide derivatization protocol

W. Gmeiner, J. Lown,, R. Pon, 1991 .

Reusable solid-phase supports for oligonucleotides and antisense therapeutics

Zhiqian Guo, R. Pon, R. R. Deshmukh, 2001 .

Efficient and Rapid Coupling of Nucleosides to Amino Derivatized Solid-Phase Supports

R. Pon, Shuyuan Yu, 1999 .

The synthesis and functional evaluation of RNA and DNA polymers having the sequence of Escherichia coli tRNA(fMet).

R. Cedergren, N. Usman, J. Perreault, 1989, European journal of biochemistry.

Tandem oligonucleotide synthesis on solid-phase supports for the production of multiple oligonucleotides.

R. Pon, Y. Sanghvi, Shuyuan Yu, 2002, The Journal of organic chemistry.

A survey of nucleic acid services in core laboratories.

G A Buck, R T Pon, R L Niece, 1994, BioTechniques.

Structure of a DNA duplex that contains alpha-anomeric nucleotides and 3'-3' and 5'-5' phosphodiester linkages: coexistence of parallel and antiparallel DNA.

J. Van De Sande, J. Aramini, R. Pon, 1996, Biochemistry.

Sequence dependent conformation and local geometry of the conserved branch site sequence element d(TpApCpTpApApC), essential for yeast mRNA splicing, deduced from high resolution 1H-NMR.

J. Lown,, D. Chang, R. Pon, 1987, Journal of biomolecular structure & dynamics.

Structure and conformation of the duplex consensus 5'-splice site d[(CpApGpGpTpApApGpT).(ApCpTpTpApCpCpTpG)] deduced from high field 1H-NMR of the non-exchangeable and imino protons.

J. Lown,, D. Chang, R. Pon, 1987, Journal of biomolecular structure & dynamics.

Solution structure of phage lambda half-operator DNA by use of NMR, restrained molecular dynamics, and NOE-based refinement.

B. Sykes, J. Baleja, R. Pon, 1990, Biochemistry.

Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV.

J. Aramini, R. Cunningham, R. Pon, 2004, Journal of molecular biology.

An Algorithm Measuring Donor Cell-Free DNA in Plasma of Cellular and Solid Organ Transplant Recipients That Does Not Require Donor or Recipient Genotyping

Steven R. Martin, Steven C. Greenway, Aneal Khan, 2016, Front. Cardiovasc. Med..

The Official Journal of the Association of Biomolecular Resource Facilities F Research@bullettechnology Communication@bulleteducation R Ab Mission Statement from the By-laws of the Association of Biomolecular Resource Facilities Abrf Electronic Communications Email and Web Addresses for Contacting A

U. Hellman, K. Clauser, J. Rush, 2000 .

Two amino acids, Phe 16 and Ala 776, on the polyprotein are most likely to be responsible for the diabetogenicity of encephalomyocarditis virus.

R. Pon, D. Giron, Y. Bae, 1990, The Journal of general virology.

A 1H-NMR study of the DNA binding characteristics of thioformyldistamycin, an amide isosteric lexitropsin.

M. Singh, T. Joseph, S. Kumar, 1992, Biochemistry.

Sequence specific molecular recognition by a monocationic lexitropsin of the decadeoxyribonucleotide d-[CATGGCCATG]2: structural and dynamic aspects deduced from high field 1H-NMR studies.

R T Pon, J. Lown,, J. Hartley, 1988, Nucleic acids research.

Solid-phase oligonucleotide synthesis and flow cytometric analysis with microspheres encoded with covalently attached fluorophores.

R T Pon, A. Watson, R. Pon, 2000, Bioconjugate chemistry.

SILYL PROTECTING GROUPS IN NUCLEOSIDE AND NUCLEOTIDE CHEMISTRY. PART XIII. THE CHEMICAL SYNTHESIS OF OLIGORIBONUCLEOTIDES. IX. A COMPARISON OF PROTECTING GROUPS IN THE DICHLORIDITE PROCEDURE

J. Seifert, R. Pon, M. Nemer, 1981 .

Use of shaped pulses for semi‐selective excitation of imino 1H resonances in duplex DNA and RNA

W. Gmeiner, R. Pon, P. Sahasrabudhe, 1995 .

Molecular recognition and binding of a GC site-avoiding thiazole-lexitropsin to the decadeoxyribonucleotide d-[CGCAATTGCG]2: 1H-NMR evidence for thiazole intercalation.

S. Kumar, J. Zimmermann, A. Sapse, 1990, Journal of biomolecular structure & dynamics.