F. Flett

发表

Growth rate control of protein and nucleic acid content in Streptomyces coelicolor A3(2) and Escherichia coli B/r.

S. Oliver, P. Butler, N. Shahab, 1996, Microbiology.

High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes.

F. Flett, V. Mersinias, C. Smith, 1997, FEMS microbiology letters.

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

Jason Micklefield, Zohreh Hojati, Barrie Wilkinson, 2002, Chemistry & biology.

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

K. C. Morris, Mohammed Salah Ibrahim, K. Y. Wong, 2022, medRxiv.

The Streptomyces lividans 66 chromosome contains a 1 MB deletogenic region flanked by two amplifiable regions

J. Cullum, F. Flett, Oliver Wafzig, 1993, Molecular and General Genetics MGG.

Active-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates.

J. Micklefield, F. Flett, Colin P. Smith, 2004, Journal of the American Chemical Society.

Stabilization of Streptomyces lividans by Homologous Recombinational Insertion

J. Cullum, P. Kaiser, F. Flett, 1992, Bio/Technology.

An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2)

S. Oliver, G. Hobbs, D. C. Gardner, 1992, Journal of bacteriology.

Click chemistry generated model DNA-peptide heteroconjugates as tools for mass spectrometry.

C. Mackay, F. Flett, J. Walton, 2015, Analytical chemistry.

DNA rearrangements associated with instability of an arginine gene in Streptomyces coelicolor A3(2)

J. Cullum, F. Flett, J. Platt, 1987, Journal of basic microbiology.

A ‘Gram‐negative‐type’ DNA polymerase III is essential for replication of the linear chromosome of Streptomyces coelicolor A3(2)

F. Flett, Colin P. Smith, V. Mersinias, 1999, Molecular microbiology.

DNA amplification and genetic instability in Streptomyces.

J. Cullum, F. Flett, J. Altenbuchner, 1986, Biotechnology & genetic engineering reviews.

Structural basis for DNA 3′-end processing by human tyrosyl-DNA phosphodiesterase 1

C. Mackay, F. Flett, J. Richardson, 2018, Nature Communications.

Genetic instability in streptomycetes.

J. Cullum, F. Flett, W. Piendl, 1988, Microbiological sciences.

DNA deletions in spontaneous chloramphenicol-sensitive mutants of Streptomyces coelicolor A3(2) and Streptomyces lividans 66

J. Cullum, F. Flett, 1987, Molecular and General Genetics MGG.

Pigmented antibiotic production by Streptomyces coelicolor A3(2): kinetics and the influence of nutrients

Stephen G. Oliver, Glyn Hobbs, S. Oliver, 1990 .

Isolation and characterization of temperature-sensitive mutants of Streptomyces coelicolor A3(2) blocked in macromolecular synthesis.

S. Oliver, F. Flett, J. Platt, 1992, Journal of general microbiology.

Development of an insect-cell-based assay for detection of kinase inhibition using NF-kappaB-inducing kinase as a paradigm.

D. Tew, S. Gul, F. Flett, 2009, The Biochemical journal.

Mapping protein-DNA interactions using UV cross-linking and mass spectrometry

F. Flett, 2014 .

New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures

K. Chater, F. Flett, G. Bucca, 2007, BMC Genomics.

Intraspecific and intergeneric mobilization of non-conjugative resistance plasmids by a 24.5 megadalton conjugative plasmid of Neisseria gonorrhoeae.

J. Saunders, F. Flett, G. Humphreys, 1981, Journal of general microbiology.

Functional evidence that the principal DNA replication origin of the Streptomyces coelicolor chromosome is close to the dnaA-gyrB region

S. Oliver, G. Hobbs, F. Flett, 1994, Journal of bacteriology.

An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium-dependent lipopeptide antibiotics.

B. Wilkinson, J. Micklefield, F. Flett, 2007, Microbiology.

Analysis of Amplifications and Deletions in Streptomyces Species

J. Cullum, D. Hranueli, F. Flett, 1991 .

A common host specificity in the restriction and modification of a bacteriophage by three distinct Streptomyces species.

R. Kirby, F. Flett, S. Wotton, 1979, Journal of general microbiology.

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

K. C. Morris, Michele R. Shaw, Mohammed Salah Ibrahim, 2023, The Lancet.

Analysis of Large Deletions and Characterization of the Deletion Endpoints Associated with an Amplifiable DNA Region in Streptomyces Lividans

J. Cullum, F. Flett, W. Piendl, 1991 .