P. Mccombe

T. Woodruff, P. Mccombe, John D. Lee, 2022, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Clinical and histological findings in proteolipid protein-induced experimental autoimmune encephalomyelitis (EAE) in the lewis rat. Distribution of demyelination differs from that in EAE induced by other antigens

J. Chalk, M. Pender, P. Mccombe, 1994, Journal of the Neurological Sciences.

Expression of CD45RC and Ia antigen in the spinal cord in acute experimental allergic encephalomyelitis: An immunocytochemical and flow cytometric study

M. Pender, P. Mccombe, J. Jersey, 1992, Journal of the Neurological Sciences.

Apoptosis of alpha beta T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance.

M. Pender, P. Mccombe, K. Nguyen, 1992, Journal of autoimmunity.

The Effects of Pregnancy on Myelin Basic Protein‐induced Experimental Autoimmune Encephalomyelitis in Lewis Rats: Suppression of Clinical Disease, Modulation of Cytokine Expression in the Spinal Cord Inflammatory Infiltrate and Suppression of Lymphocyte Proliferation by Pregnancy Sera

P. Mccombe, J. Harness, 2001 .

Restoration of conduction in the spinal roots correlates with clinical recovery from experimental autoimmune encephalomyelitis

J. Chalk, M. Pender, P. Mccombe, 1995, Muscle & nerve.

Early pregnancy factor treatment suppresses the inflammatory response and adhesion molecule expression in the spinal cord of SJL/J mice with experimental autoimmune encephalomyelitis and the delayed-type hypersensitivity reaction to trinitrochlorobenzene in normal BALB/c mice

Bing Zhang, P. Mccombe, M. Walsh, 2003, Journal of the Neurological Sciences.

Association of Latitude and Exposure to Ultraviolet B Radiation With Severity of Multiple Sclerosis: An International Registry Study.

J. Lechner-Scott, M. Onofrj, M. Slee, 2022, Neurology.

The relationship between limb dominance, disease lateralization and spread of weakness in amyotrophic lateral sclerosis (ALS)

P. Mccombe, R. Henderson, Matthew S. Devine, 2013, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Effects of biological sex and pregnancy in experimental autoimmune encephalomyelitis: It’s complicated

P. Mccombe, J. Greer, 2022, Frontiers in Immunology.

Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study

L. Kasten, H. Hartung, E. Havrdová, 2016 .

Lower hypothalamic volume with lower body mass index is associated with shorter survival in patients with amyotrophic lateral sclerosis

Thomas B. Shaw, C. Guo, J. Fripp, 2022, European journal of neurology.

Apoptosis of V beta 8.2+ T lymphocytes in the spinal cord during recovery from experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein.

M. Pender, P. Mccombe, Z. Tabi, 1996, Journal of the neurological sciences.

A Simple and Reliable Immunohistochemical Method for Colocalization of 2 Antigens in the Same Cells of Paraffin-embedded Tissues

P. Mccombe, V. Catts, Jun Yan, 2013, Applied immunohistochemistry & molecular morphology : AIMM.

Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics

Ashley R. Jones, N. Wray, R. Dobson, 2020, Cell reports.

Women who contributed to past research in multiple sclerosis

P. Mccombe, 2019, Multiple sclerosis.

Effect of Disease Modifying Therapy on Disability in Relapsing-Remitting Multiple Sclerosis Over 15 Years.

J. Lechner-Scott, M. Slee, A. Kermode, 2020, Neurology.

Immunotherapy prevents long-term disability in relapsing multiple sclerosis over 15 years

J. Lechner-Scott, M. Slee, A. Kermode, 2019, bioRxiv.

Gender differences in autoimmune disease

P. Mccombe, S. Ngo, F. Steyn, 2014, Frontiers in Neuroendocrinology.

Chronic inflammatory demyelinating polyradiculoneuropathy and severe peripheral oedema: a renal explanation

P. Mccombe, R. Henderson, C. Lander, 2000, Journal of Clinical Neuroscience.

Sex differences in Guillain Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and experimental autoimmune neuritis

P. Mccombe, J. Greer, T. Hardy, 2022, Frontiers in Immunology.

Bladder dysfunction in multiple sclerosis

Pamela A McCombe, Michael W. Jackson, P. Mccombe, 2009, Expert review of neurotherapeutics.

The peripheral neuropathy of vitamin B12 deficiency

P. Mccombe, J. McLeod, 1984, Journal of the Neurological Sciences.

The role of epigenetic mechanisms and processes in autoimmune disorders

P. Mccombe, J. Greer, 2012, Biologics : targets & therapy.

Statistical modelling of neuron degeneration

P. Mccombe, R. Henderson, G. Ridall, 2013 .

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Ewout J. N. Groen, Annelot M. Dekker, Ross P. Byrne, 2021, Nature Genetics.

Genome-wide study of DNA methylation in Amyotrophic Lateral Sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways

Annelot M. Dekker, Ahmad Al Khleifat, N. Wray, 2021, medRxiv.

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

Annelot M. Dekker, N. Wray, A. McRae, 2022, Science Translational Medicine.

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

R. Marioni, P. Visscher, N. Wray, 2021, Genome biology.

Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis

J. Lechner-Scott, M. Slee, L. Blizzard, 2016, Journal of Neurology, Neurosurgery & Psychiatry.

The Short and Long-Term Effects of Pregnancy on Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

Pamela A McCombe, P. Mccombe, 2018, Journal of clinical medicine.

A new era in the treatment of multiple sclerosis

Jeannette Lechner-Scott, Helmut Butzkueven, John King, 2015, The Medical journal of Australia.

Effect of gender on T-cell proliferative responses to myelin proteolipid protein antigens in patients with multiple sclerosis and controls.

M. Pender, P. Mccombe, J. Greer, 2004, Journal of autoimmunity.

Gender issues in multiple sclerosis

P. Mccombe, 2003, Expert review of neurotherapeutics.

Surges of Increased T Cell Reactivity to an Encephalitogenic Region of Myelin Proteolipid Protein Occur More Often in Patients with Multiple Sclerosis Than in Healthy Subjects1

M. Pender, D. Purdie, M. Good, 2000, The Journal of Immunology.

A study of human T-cell lines generated from multiple sclerosis patients and controls by stimulation with peptides of myelin basic protein

R. Houghten, M. Pender, M. Good, 1996, Journal of Neuroimmunology.

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

Victoria E. Jackson, M. Brown, J. Reveille, 2020, Nature Communications.

What do we know about the variability in survival of patients with amyotrophic lateral sclerosis?

N. Wray, P. Mccombe, R. Henderson, 2020, Expert review of neurotherapeutics.

Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

P. Visscher, N. Wray, A. McRae, 2020, npj Genomic Medicine.

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1

N. Wray, A. McRae, R. Ophoff, 2022, Genome Medicine.

Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: Frequency of abnormality and effect on survival

Ashwag R. Alruwaili, P. Mccombe, R. Henderson, 2017, Journal of the Neurological Sciences.

Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia

P. Visscher, N. Wray, A. McRae, 2021, European Journal of Human Genetics.

Progression and survival of patients with motor neuron disease relative to their fecal microbiota

N. Wray, R. V. van Eijk, P. Mccombe, 2020, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

J. Lechner-Scott, O. Pearson, M. Slee, 2019, JAMA.

Early clinical markers of aggressive multiple sclerosis.

M. Slee, M. Trojano, F. Grand'Maison, 2019, Brain : a journal of neurology.

Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability

P. Mccombe, Jun Yan, J. Greer, 2012, Journal of Neuroimmunology.

Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses

H. Varmus, J. Bishop, D. Spector, 1978, Cell.

Interaction of neurotransmitters and neurochemicals with lymphocytes

E. Sloan, P. Mccombe, S. Mattarollo, 2019, Journal of Neuroimmunology.

Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms

P. Mccombe, J. Greer, 2011, Journal of Neuroimmunology.

Chronic inflammatory demyelinating polyradiculoneuropathy associated with pregnancy

J. Pollard, P. Mccombe, P. McManis, 1987, Annals of neurology.

The effects of prophylactic cyclosporin A on experimental allergic neuritis (EAN) in the Lewis rat. Induction of relapsing EAN using low dose cyclosporin A

M. Pender, P. Mccombe, S. Kreek, 1990, Journal of Neuroimmunology.

Peripheral sensorimotor and autonomic neuropathy associated with systemic lupus erythematosus. Clinical, pathological and immunological features.

T. Ingall, J. Pollard, P. Mccombe, 1987, Brain : a journal of neurology.

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

P. Visscher, Sonia Shah, N. Wray, 2017, Nature Communications.

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Ewout J. N. Groen, Annelot M. Dekker, Ross P. Byrne, 2021, Nature Genetics.

Increased expression of the hypoxia‐related genes in peripheral blood leukocytes of human subjects with acute ischemic stroke

P. Mccombe, Jun Yan, J. Greer, 2014 .

Immune activation in the peripheral blood of patients with acute ischemic stroke

J. Pandian, J. O'Sullivan, S. Read, 2009, Journal of Neuroimmunology.

Reduced IκB-α Protein Levels in Peripheral Blood Cells of Patients with Multiple Sclerosis—A Possible Cause of Constitutive NF-κB Activation

M. Pender, P. Mccombe, Jun Yan, 2020, Journal of clinical medicine.

Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort

P. Visscher, Sonia Shah, N. Wray, 2017, Molecular genetics & genomic medicine.

Natalizumab, Fingolimod, and Dimethyl Fumarate Use and Pregnancy-Related Relapse and Disability in Women With Multiple Sclerosis

J. Lechner-Scott, M. Onofrj, F. Grand'Maison, 2021, Neurology.

Phenotypic variability within the desminopathies: A case series of three patients

P. Mccombe, R. Henderson, R. Denman, 2023, Frontiers in Neurology.

Cylindrical spirals in two families: Clinical and genetic investigations

G. Ravenscroft, N. Laing, I. Ojanguren, 2019, Neuromuscular Disorders.

Case report: Adult-onset limb girdle muscular dystrophy in sibling pair due to novel homozygous LAMA2 missense variant

L. Waddell, E. Oates, S. Cooper, 2023, Frontiers in Neurology.

Sexual dimorphism in autoimmune disease.

I. Mackay, P. Mccombe, J. Greer, 2009, Current molecular medicine.

Familial occurrence of multiple sclerosis with thyroid disease and systemic lupus erythematosus

J. Chalk, M. Pender, P. Mccombe, 1990, Journal of the Neurological Sciences.

Genetics of Guillain‐Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): current knowledge and future directions

P. Mccombe, S. Blum, 2014, Journal of the peripheral nervous system : JPNS.

Sexual Dimorphism in the Immune System

P. Mccombe, J. Greer, 2020, The Autoimmune Diseases.

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 3 Treatment practicalities and recommendations

S. Broadley, J. Lechner-Scott, M. Slee, 2014, Journal of Clinical Neuroscience.

The frequencies of Killer immunoglobulin-like receptors and their HLA ligands in chronic inflammatory demyelinating polyradiculoneuropathy are similar to those in Guillian Barre syndrome but differ from those of controls, suggesting a role for NK cells in pathogenesis

P. Mccombe, S. Blum, P. Csurhes, 2015, Journal of Neuroimmunology.

Immune and Inflammatory Responses to Stroke: Good Or Bad?

S. Read, P. Mccombe, S. Read, 2008, International journal of stroke : official journal of the International Stroke Society.

Interleukin-6 Gene Promoter-572 C Allele may Play a Role in Rate of Disease Progression in Multiple Sclerosis

Pamela A. McCombe, M. Pender, P. Mccombe, 2012, International journal of molecular sciences.

The Peripheral Immune System and Amyotrophic Lateral Sclerosis

T. Woodruff, P. Mccombe, R. Henderson, 2020, Frontiers in Neurology.

The Role of Immune and Inflammatory Mechanisms in ALS

P. Mccombe, R. Henderson, 2011, Current molecular medicine.

Effects of gender in amyotrophic lateral sclerosis.

Pamela A McCombe, Robert D Henderson, P. Mccombe, 2010, Gender medicine.

Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis

M. Pender, M. Good, P. Mccombe, 2003, Journal of Clinical Neuroscience.

Impairments to the GH-IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis.

M. Bellingham, J. Veldhuis, P. Mccombe, 2012, Endocrinology.

A case of Lhermitte-Duclos disease.

P. Mccombe, B. Warren, 1983, Clinical and experimental neurology.

Post-COVID Opsoclonus Myoclonus Syndrome: A Case Report From Pakistan

P. Mccombe, Nemat Khan, Talha Durrani, 2021, Frontiers in Neurology.

Increased immunoreactivity to two overlapping peptides of myelin proteolipid protein in multiple sclerosis.

M. Pender, M. Good, P. Mccombe, 1997, Brain : a journal of neurology.

Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: Evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset

A. N. Pettitt, Pamela A. McCombe, R. D. Henderson, 2012, Clinical Neurophysiology.

Elevated plasma levels of D-serine in some patients with amyotrophic lateral sclerosis

D. Pow, P. Mccombe, R. Henderson, 2020, Amyotrophic lateral sclerosis & frontotemporal degeneration.

ALPHA-1 Antitrypsin Phenotypes in Guillain-Barre Syndrome, Chronic Inflammatory Demyelinating Polyneuropathy, and Multiple Sclerosis

J. Pollard, P. Mccombe, S. Hammond, 1984 .

Body mass index and dietary intervention: Implications for prognosis of amyotrophic lateral sclerosis

P. Mccombe, S. Ngo, F. Steyn, 2014, Journal of the Neurological Sciences.

Correlation of Adrenomedullin gene expression in peripheral blood leukocytes with severity of ischemic stroke

S. Rose, A. Coulthard, S. Read, 2014, The International journal of neuroscience.

Low plasma hyaluronan is associated with faster functional decline in patients with amyotrophic lateral sclerosis

P. Mccombe, R. Henderson, S. Ngo, 2021, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels

P. Mccombe, A. Lee, B. J. Arachchige, 2019, Journal of the Neurological Sciences.

Altered Metabolic Homeostasis in Amyotrophic Lateral Sclerosis: Mechanisms of Energy Imbalance and Contribution to Disease Progression

Z. Ioannides, P. Mccombe, R. Henderson, 2016, Neurodegenerative Diseases.

Tract integrity in amyotrophic lateral sclerosis: 6–month evaluation using MR diffusion tensor imaging

Kerstin Pannek, Nyoman D. Kurniawan, Ashwag R. Alruwaili, 2019, BMC Medical Imaging.

Missense mutations in the MLKL ‘brace’ region lead to lethal neonatal inflammation in mice and are present in high frequency in humans

M. Brown, J. Reveille, A. Bassuk, 2019, bioRxiv.

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 1 Historical and established therapies

S. Broadley, J. Lechner-Scott, M. Slee, 2014, Journal of Clinical Neuroscience.

Assessment of Motor Units in Neuromuscular Disease

P. Mccombe, R. Henderson, 2016, Neurotherapeutics.

Motor Unit Number Estimation—A Bayesian Approach

Anthony N Pettitt, Pamela A McCombe, P Gareth Ridall, 2006, Biometrics.

Apoptotic elimination of Vβ8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of Vβ8.2+ encephalitogenic T cells

M. Pender, P. Mccombe, Z. Tabi, 1994 .

Vestibular and ventilatory dysfunction in sensory and autonomic neuropathy associated with primary Sjörgren's syndrome.

M. Pender, P. Mccombe, G. Sheean, 1992, Journal of neurology, neurosurgery, and psychiatry.

Study of motor asymmetry in ALS indicates an effect of limb dominance on onset and spread of weakness, and an important role for upper motor neurons

M. Kiernan, P. Mccombe, R. Henderson, 2014, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Lower motor neuron degeneration in ALS 1 Use of Bayesian MUNE to show differing rate of loss of motor units in subgroups of ALS Running Title : Subgroups of

P. Mccombe, Baumann, Als, 2014 .

Autoimmune Neurological Disease

M. Pender, P. Mccombe, 1995 .

Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort

Thi V. Duong, S. Venkatesh, T. Duong, 2016, BMJ Open.

Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects

P. Mccombe, R. Henderson, A. Lee, 2018, Amyotrophic lateral sclerosis & frontotemporal degeneration.

A Case Series of Patients With Autoimmune Myasthenia Gravis in Association With Invasive Thymoma

P. Mccombe, R. Henderson, S. Blum, 2016, Journal of clinical neuromuscular disease.

Biofluid biomarkers of amyotrophic lateral sclerosis

M. Rogers, P. Mccombe, R. Henderson, 2022 .

Novel Variants of ANO5 in Two Patients With Limb Girdle Muscular Dystrophy: Case Report

P. Mccombe, R. Henderson, F. Garton, 2022, Frontiers in Neurology.

Cumulative influence of parity-related genomic changes in multiple sclerosis

N. Wray, D. Mehta, Shivangi Wani, 2019, Journal of Neuroimmunology.

Multiparity in women with multiple sclerosis causes less long-term disability: No

P. Mccombe, LK Callaway, 2014, Multiple sclerosis.

Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke

P. Mccombe, R. Henderson, S. Read, 2011, Journal of the Neurological Sciences.

Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome

P. Mccombe, Jun Yan, J. Greer, 2016, Journal of Neuroimmunology.

Neurofilaments as Biomarkers for Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis

M. David, P. Mccombe, R. Henderson, 2016, PloS one.

Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis

J. Lechner-Scott, M. Slee, A. Kermode, 2018, Multiple sclerosis.

Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis

T. Woodruff, J. O'Sullivan, P. Mccombe, 2015, Journal of the Neurological Sciences.

Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study

Kerstin Pannek, Christopher Bell, Robert Henderson, 2012, NeuroImage.

Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls

P. Mccombe, R. Henderson, A. Lee, 2020, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Switch to natalizumab versus fingolimod in active relapsing–remitting multiple sclerosis

J. Lechner-Scott, M. Slee, M. Trojano, 2015, Annals of neurology.

A combined tract-based spatial statistics and voxel-based morphometry study of the first MRI scan after diagnosis of amyotrophic lateral sclerosis with subgroup analysis.

Ashwag R. Alruwaili, N. Kurniawan, A. Coulthard, 2017, Journal of neuroradiology. Journal de neuroradiologie.

A developmental perspective on bulbar involvement in amyotrophic lateral sclerosis

P. Mccombe, R. Henderson, Anna M Farrell, 2013, Amyotrophic lateral sclerosis & frontotemporal degeneration.

MRI Patterns Distinguish AQP4 Antibody Positive Neuromyelitis Optica Spectrum Disorder From Multiple Sclerosis

S. Broadley, J. Lechner-Scott, M. Slee, 2021, Frontiers in Neurology.

The effectiveness of natalizumab vs fingolimod-A comparison of international registry studies.

E. Leray, J. Lechner-Scott, M. Onofrj, 2021, Multiple sclerosis and related disorders.

Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosis

T. Woodruff, M. Ruitenberg, P. Mccombe, 2020, Brain communications.

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1G93A mice

P. G. Ridall, A. Pettitt, M. Bellingham, 2012, Clinical Neurophysiology.

Hypermetabolism in ALS is associated with greater functional decline and shorter survival

N. Wray, L. H. van den Berg, A. Henders, 2018, Journal of Neurology, Neurosurgery, and Psychiatry.

Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: Effect on outcome

P. Mccombe, Jun Yan, J. Greer, 2015, Journal of Neuroimmunology.

Long-term follow-up of patients with myasthenia gravis treated with low-dose rituximab

P. Mccombe, R. Henderson, D. Gillis, 2018, Journal of Neurology, Neurosurgery, and Psychiatry.

Riluzole: a glimmer of hope in the treatment of motor neurone disease

P. Mccombe, R. Henderson, 2005, The Medical journal of Australia.

Autoimmune neurological disease: Autoimmune diseases of the neuromuscular junction and other disorders of the motor unit

M. Pender, P. Mccombe, 1995 .

Sensitivity and specificity of the ECAS in identifying executive function and social cognition deficits in MND

Mia N. Phillips, G. Robinson, P. Mccombe, 2023, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Postural orthostatic tachycardia syndrome: an underrecognized disorder

J. Pandian, P. Mccombe, R. Henderson, 2007, Internal medicine journal.

An Australian State-Based Cohort Study of Autoimmune Encephalitis Cases Detailing Clinical Presentation, Investigation Results, and Response to Therapy

S. Broadley, P. Mccombe, C. Muller, 2021, Frontiers in Neurology.

Use of respiratory function tests to predict survival in amyotrophic lateral sclerosis

Pamela A McCombe, Robert D Henderson, Fusun Baumann, 2010, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

Sensorimotor peripheral neuropathy in rheumatoid arthritis.

J. Chalk, M. Pender, P. Mccombe, 1991, Clinical and experimental neurology.

Incidence and prevalence of NMOSD in Australia and New Zealand

K. Dear, S. Broadley, J. Lechner-Scott, 2017, Journal of Neurology, Neurosurgery, and Psychiatry.

Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice.

M. Bellingham, J. Veldhuis, P. Mccombe, 2013, Endocrinology.

Comparative Effectiveness of Autologous Hematopoietic Stem Cell Transplant vs Fingolimod, Natalizumab, and Ocrelizumab in Highly Active Relapsing-Remitting Multiple Sclerosis.

H. Atkins, J. Lechner-Scott, M. Onofrj, 2023, JAMA neurology.

Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis

J. Lechner-Scott, M. Slee, M. Trojano, 2020, Multiple sclerosis.

Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study

J. Lechner-Scott, O. Pearson, M. Slee, 2017, The Lancet Neurology.

Female infertility and multiple sclerosis: Is this an issue?

P. Mccombe, E. Stenager, 2015, Multiple sclerosis.

Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study)

C. Pozzilli, X. Montalban, P. Vermersch, 2017 .

Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis.

L. Kappos, E. Leray, J. Lechner-Scott, 2022, Neurology.

Response to treatment in NMOSD: the Australasian experience.

S. Broadley, J. Lechner-Scott, M. Slee, 2021, Multiple sclerosis and related disorders.

Cladribine: a multicentre, LOng-term efficacy and Biomarker Australian Study (CLOBAS). Protocol for a six- year, real-world, phase IV study of people with multiple sclerosis taking cladribine tablets. (Preprint)

J. Lechner-Scott, A. Kermode, R. Lea, 2020 .

Delay from treatment start to full effect of immunotherapies for multiple sclerosis.

L. Kappos, P. Vermersch, E. Leray, 2020, Brain : a journal of neurology.

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 2 New and emerging therapies and their efficacy

S. Broadley, J. Lechner-Scott, M. Slee, 2014, Journal of Clinical Neuroscience.

Genome-wide association study in Guillain-Barré syndrome

M. Brown, Zhixiu Li, Ying Ji, 2018, Journal of Neuroimmunology.

Mutations in heat shock protein beta-1 (HSPB1) are associated with a range of clinical phenotypes related to different patterns of motor neuron dysfunction: A case series

N. Wray, P. Mccombe, F. Garton, 2020, Journal of the Neurological Sciences.

Levels of interleukin 33 and soluble suppression of tumorigenicity 2 in acute ischemic stroke

P. Mccombe, Jun Yan, C. Pfluger, 2013 .

Age of Onset and Length of Survival of Queensland Patients with Amyotrophic Lateral Sclerosis: Details of Subjects with Early Onset and Subjects with Long Survival

G. Robinson, P. Mccombe, R. Henderson, 2022, Neurodegenerative Diseases.

Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with amyotrophic lateral sclerosis

L. H. van den Berg, R. V. van Eijk, P. Mccombe, 2021, European journal of neurology.

Disability accrual in primary and secondary progressive multiple sclerosis

L. Kappos, J. Lechner-Scott, M. Onofrj, 2023, Journal of Neurology, Neurosurgery, and Psychiatry.

Autoantibody‐mediated bowel and bladder dysfunction in a patient with chronic, nondiabetic neuropathy

P. Mccombe, T. Gordon, M. W. Jackson, 2008, Muscle & nerve.

Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis

Kerstin Pannek, Nyoman D. Kurniawan, Ashwag R. Alruwaili, 2020, BMC Medical Imaging.

Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study)

D. Arnold, C. Pozzilli, H. Hartung, 2019 .

Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis

L. Kappos, J. Lechner-Scott, M. Onofrj, 2023, European journal of neurology.

Functional Characterisation of a GWAS Risk Locus Identifies GPX3 as a Lead Candidate Gene in ALS

N. Wray, A. McRae, R. Ophoff, 2020 .

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

P. Visscher, N. Wray, X. Chen, 2017, Nature Communications.

A protective effect of early pregnancy factor on experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein

P. Mccombe, H. Morton, A. Cavanagh, 2003, Journal of the Neurological Sciences.

Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study)

D. Arnold, C. Pozzilli, H. Hartung, 2019 .

Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).

X. Montalban, P. Vermersch, H. Hartung, 2016 .

Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: causal inference to emulate a multiarm randomised trial

E. Stuart, L. Kappos, J. Lechner-Scott, 2023, Journal of Neurology, Neurosurgery, and Psychiatry.

Parallel Session 13 – Late Breaking News

J. Lechner-Scott, M. Slee, F. Grand'Maison, 2009 .

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program (S24.008)

L. Kasten, C. Chambers, A. Achiron, 2016 .

Early pregnancy factor and experimental autoimmune encephalomyelitis

P. Mccombe, H. Morton, A. Cavanagh, 1997 .

Phase 1b dose-escalation, safety, and pharmacokinetic study of IC14, a monoclonal antibody against CD14, for the treatment of amyotrophic lateral sclerosis

P. Mccombe, R. Henderson, M. Appleby, 2021, Medicine.

RNA-seq analysis of skeletal muscle in motor neurone disease cases and controls

N. Wray, A. McRae, P. Mccombe, 2023, medRxiv.

Results of Bayesian statistical analysis in normal and ALS subjects.

A N Pettitt, R D Henderson, P G Ridall, 2009, Supplements to Clinical neurophysiology.

Anthropometric measures are not accurate predictors of fat mass in ALS

Z. Ioannides, P. Mccombe, R. Henderson, 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Predictions of resting energy expenditure in amyotrophic lateral sclerosis are greatly impacted by reductions in fat free mass

Z. Ioannides, P. Mccombe, R. Henderson, 2017 .

Monoclonal immunoglobulin bands in the cerebrospinal fluid.

P. Mccombe, N. Brown, A. E. Barr, 1991, Australian and New Zealand journal of medicine.

Efficacy of Cladribine Tablets as a Treatment for People With Multiple Sclerosis: Protocol for the CLOBAS Study (Cladribine, a Multicenter, Long-term Efficacy and Biomarker Australian Study)

J. Lechner-Scott, A. Kermode, R. Lea, 2021, JMIR research protocols.

Focal conduction block in the dorsal root ganglion in experimental allergic neuritis

M. Pender, P. Mccombe, G. P. Stanley, 1992, Annals of neurology.

Comparative effectiveness in multiple sclerosis: A methodological comparison

J. Lechner-Scott, M. Onofrj, A. Al-Asmi, 2023, Multiple sclerosis.

Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease

E. Wolvetang, P. Mccombe, R. Henderson, 2023, Journal of Experimental Neurology.

Cronkhite-Canada syndrome associated with peripheral neuropathy.

J. Chalk, M. Pender, P. Mccombe, 1991, Australian and New Zealand journal of medicine.

Aggressive form of multiple sclerosis can be predicted early after disease onset

M. Slee, M. Trojano, F. Grand'Maison, 2019 .

Proteomic investigation of ALS motor cortex identifies known and novel pathogenetic mechanisms

P. Mccombe, B. J. Arachchige, R. Henderson, 2023, Journal of the Neurological Sciences.

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

R. Marioni, P. Visscher, N. Wray, 2021, Genome Biology.

Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination

S. Broadley, A. Kermode, D. Wakefield, 2019, Acta Neuropathologica Communications.

Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice.

M. Bellingham, P. Mccombe, S. Ngo, 2013, Endocrinology.

Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis

J. Lechner-Scott, O. Pearson, M. Slee, 2019, JAMA.

Longitudinal changes in intrinsic motoneuron excitability in amyotrophic lateral sclerosis are dependent on disease progression.

P. Mccombe, L. Orssatto, Warwick Rivlin, 2023, The Journal of physiology.

Associations of postprandial ghrelin, liver-expressed antimicrobial peptide 2 and leptin levels with body composition, disease progression and survival in patients with amyotrophic lateral sclerosis.

J. Zigman, P. Mccombe, S. Ngo, 2023, European journal of neurology.

Increased levels of activated T-cells and reduced levels of CD4/CD25+ cells in peripheral blood of Guillain-Barré syndrome patients compared to controls

P. Mccombe, J. Harness, 2008, Journal of Clinical Neuroscience.

Multifocal motor neuropathy: Improvement after autologous bone marrow transplantation

P. Mccombe, J. Morton, N. Saines, 2002 .

Circulating brain derived neurotrophic factor (BDNF) and frequency of BDNF positive T cells in peripheral blood in human ischemic stroke: Effect on outcome

P. Mccombe, Jun Yan, J. Greer, 2015, Journal of Neuroimmunology.

Genetics of Guillain‐Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): current knowledge and future directions

P. Mccombe, S. Blum, 2014, Journal of the peripheral nervous system : JPNS.

Use and monitoring of low dose rituximab in myasthenia gravis

P. Mccombe, R. Henderson, P. Pillans, 2010, Journal of Neurology, Neurosurgery & Psychiatry.

Genome-wide association study in Guillain-Barré syndrome

M. Brown, Zhixiu Li, Ying Ji, 2018, Journal of Neuroimmunology.

T cells from patients with Guillain-Barré syndrome produce interferon-gamma in response to stimulation with the ganglioside GM1

P. Mccombe, P. Csurhes, 2010, Journal of clinical neuroscience.

Atypical clinical presentations of the A3243G mutation, usually associated with MELAS

P. Mccombe, S. Klingberg, Robert D. Henderson, 2011, Internal medicine journal.

Pregnancy Outcomes in Alemtuzumab-treated Patients With RRMS in the Phase 2 and 3 Clinical Development Program Over 16 Years

E. Celius, C. Chambers, Jiwon Oh, 2019 .

Variation in Resting Metabolic Rate Affects Identification of Metabolic Change in Geographically Distinct Cohorts of Patients With ALS.

R. V. van Eijk, P. Mccombe, S. Ngo, 2024, Neurology.

Altered skeletal muscle glucose–fatty acid flux in amyotrophic lateral sclerosis

J. Loeffler, P. Mccombe, S. Ngo, 2020, Brain communications.

Examining the environmental risk factors of progressive-onset and relapsing-onset multiple sclerosis: recruitment challenges, potential bias, and statistical strategies

J. Lechner-Scott, M. Slee, A. Ponsonby, 2023, Journal of neurology.

Determinants of therapeutic lag in multiple sclerosis

E. Leray, J. Lechner-Scott, M. Onofrj, 2021, Multiple sclerosis.

Increased constitutive activation of NF-κB p65 (RelA) in peripheral blood cells of patients with progressive multiple sclerosis

M. Pender, P. Mccombe, C. Winterford, 2018, Journal of Neuroimmunology.

Vitamin D did not reduce multiple sclerosis disease activity after a clinically isolated syndrome

J. Lechner-Scott, A. Ponsonby, H. Butzkueven, 2023, Brain : a journal of neurology.

Anthropometric measures are not accurate predictors of fat mass in ALS

Z. Ioannides, P. Mccombe, R. Henderson, 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Verbal and nonverbal fluency in amyotrophic lateral sclerosis.

P. Mccombe, A. Ceslis, Megan S. Barker, 2023, Journal of neuropsychology.

Predictors of relapse risk and treatment response in AQP4-IgG positive and seronegative NMOSD: A multicentre study.

Chao Zhu, P. Mccombe, S. Ozakbas, 2024, Journal of neurology, neurosurgery, and psychiatry.