N. Meyer

P. Shah, J. Orens, L. Ware, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Acute respiratory distress syndrome

N. Meyer, C. Calfee, L. Gattinoni, 2021, The Lancet.

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

E. Wherry, M. Betts, D. Teachey, 2021, Science Immunology.

Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization

F. Bushman, E. Wherry, J. Weaver, 2022, The Journal of infectious diseases.

Acute Lung Injury in Pregnancy

G. Schmidt, N. Meyer, 2009 .

Preparedness Tested: Severe Cerebral Malaria Presenting as a High-Risk Person Under Investigation for Ebola Virus Disease at a US Hospital

D. Pegues, M. Mikkelsen, W. Schweickert, 2020, Disaster Medicine and Public Health Preparedness.

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

Sasikanth Manne, John P. Reilly, Allison R. Greenplate, 2020, Science.

Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study

J. Christie, N. Meyer, B. Anderson, 2019, Critical Care.

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Tom R. Gaunt, Tom S. Price, Joseph T. Glessner, 2011, American journal of human genetics.

Inflammasome-regulated cytokines are critical mediators of acute lung injury.

S. Ryter, D. Christiani, A. Choi, 2012, American journal of respiratory and critical care medicine.

Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation.

D. Huh, G. Worthen, N. Meyer, 2014, American journal of respiratory and critical care medicine.

Beyond single-nucleotide polymorphisms: genetics, genomics, and other 'omic approaches to acute respiratory distress syndrome.

N. Meyer, 2014, Clinics in chest medicine.

Approaches to Acute Respiratory Distress Syndrome

N. Meyer, 2014 .

Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study

R. Gallop, M. Matthay, T. Miano, 2019, Critical Care.

Validating a Proteomic Signature of Severe COVID-19

E. Wherry, M. Betts, A. Greenplate, 2022, Critical care explorations.

Elevated Plasma Levels of Matrix Metalloproteinase-3 and Tissue-Inhibitor of Matrix Metalloproteinases-1 Associate With Organ Dysfunction and Mortality in Sepsis

T. Miano, N. Meyer, B. Anderson, 2021, Shock.

Neutropenic sepsis is associated with distinct clinical and biological characteristics: a cohort study of severe sepsis

M. Mikkelsen, J. Christie, N. Meyer, 2016, Critical Care.

Advancing precision medicine for acute respiratory distress syndrome

L. Esserman, J. Marshall, T. Standiford, 2021, The Lancet Respiratory Medicine.

Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis

Xihong Lin, D. Christiani, M. Wurfel, 2018, Intensive Care Medicine.

Fifty Years of Research in ARDS. Genomic Contributions and Opportunities

J. Christie, N. Meyer, J. Reilly, 2017, American journal of respiratory and critical care medicine.

Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome

N. Meyer, C. Calfee, 2017, The Lancet Respiratory Medicine.

Circulating markers of endothelial and alveolar epithelial dysfunction are associated with mortality in pediatric acute respiratory distress syndrome

R. Berg, S. Margulies, N. Yehya, 2016, Intensive Care Medicine.

ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio.

H. Hakonarson, Mingyao Li, R. Gallop, 2011, American journal of respiratory and critical care medicine.

A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement

G. Clermont, J. Marshall, D. Angus, 2021, American journal of respiratory and critical care medicine.

Plasma Insulin-like Growth Factor Binding Protein 7 Contributes Causally to ARDS 28-Day Mortality

F. Chen, L. Su, Ruyang Zhang, 2021, Chest.

Precision Medicine in Critical Illness: Sepsis and Acute Respiratory Distress Syndrome

N. Meyer, A. Rogers, 2019, Precision in Pulmonary, Critical Care, and Sleep Medicine.

Plasma sRAGE Acts as Genetically Regulated Causal Intermediate in Sepsis-Associated ARDS.

D. Christiani, M. Wurfel, M. Matthay, 2019, American journal of respiratory and critical care medicine.

Admission plasma levels of the neuronal injury marker neuron-specific enolase are associated with mortality and delirium in sepsis.

D. Kolson, J. Palakshappa, M. Mikkelsen, 2016, Journal of critical care.

Successful Analgesia and Sedation for Patients with Acute Heart Failure Syndromes

Jesse B. Hall, N. Meyer, Jesse B. Hall, 2008 .

New-onset IgG autoantibodies in hospitalized patients with COVID-19

E. Wherry, K. Nadeau, W. Robinson, 2021, Nature Communications.

New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19

E. Wherry, K. Nadeau, M. Radic, 2021, medRxiv.

Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans.

Mingyao Li, E. Schadt, M. Reilly, 2015, Human molecular genetics.

SNP-set analysis replicates acute lung injury genetic risk factors

Z. J. Daye, J. Christie, N. Meyer, 2012, BMC Medical Genetics.

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

Sasikanth Manne, John P. Reilly, Allison R. Greenplate, 2020, bioRxiv.

Genome Wide Association Identifies PPFIA1 as a Candidate Gene for Acute Lung Injury Risk Following Major Trauma

H. Hakonarson, Cecilia Kim, Mingyao Li, 2012, PloS one.

Gene Set Enrichment Analysis Identifies Key Innate Immune Pathways in Primary Graft Dysfunction After Lung Transplantation

J. Tobias, K. Olthoff, A. Shaked, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Erythrocytes identify complement activation in patients with COVID-19

E. Wherry, M. Betts, J. Lambris, 2021, American journal of physiology. Lung cellular and molecular physiology.

CD8 T cells compensate for impaired humoral immunity in COVID-19 patients with hematologic cancer

E. Wherry, N. E. Babady, J. Wolchok, 2021, Research square.

Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

E. Wherry, M. Betts, D. Teachey, 2020, medRxiv.

DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia

S. Rivella, Sunny Shin, B. Hahn, 2021, Science Translational Medicine.

Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death

David C. Christiani, Jason D. Christie, Michael A. Matthay, 2016, Critical Care.

PCSK9 is a critical regulator of the innate immune response and septic shock outcome

M. Reilly, C. Fjell, J. Ferguson, 2014, Science Translational Medicine.

Diagnostic biomarkers to differentiate sepsis from cytokine release syndrome in critically ill children.

Jason W. Moore, D. Teachey, S. Grupp, 2020, Blood advances.

GADD45a is a novel candidate gene in inflammatory lung injury via influences on Akt signaling

Y. Lussier, A. Husain, N. Meyer, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19

E. Wherry, L. Rauova, A. Greenplate, 2022, Frontiers in Immunology.

The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis.

M. Reilly, J. Christie, N. Meyer, 2015, Clinical journal of the American Society of Nephrology : CJASN.

Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection

B. Walker, Xu G. Yu, M. Betts, 2022, eLife.

A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.

Mingyao Li, M. Reilly, J. Ferguson, 2014, American journal of respiratory and critical care medicine.

Role of growth arrest and DNA damage-inducible α in Akt phosphorylation and ubiquitination after mechanical stress-induced vascular injury.

S. Dudek, N. Meyer, S. Sammani, 2011, American journal of respiratory and critical care medicine.

Plasma Levels of Receptor Interacting Protein Kinase-3 (RIP3), an Essential Mediator of Necroptosis, are Associated with Acute Kidney Injury in Critically Ill Trauma Patients

H. Feldman, J. Christie, N. Meyer, 2016, Shock.

African American race, obesity, and blood product transfusion are risk factors for acute kidney injury in critically ill trauma patients.

A. Localio, R. Gallop, H. Feldman, 2012, Journal of critical care.

Gastrointestinal Manifestation of Severe SARS-CoV-2 Infection in an Immunocompromised Dog

Jillian N. Whelan, S. Weiss, N. Meyer, 2021 .

Wading into the genomic pool to unravel acute lung injury genetics.

N. Meyer, Joe G. N. Garcia, 2007, Proceedings of the American Thoracic Society.

Quantitative peripheral muscle ultrasound in sepsis: Muscle area superior to thickness

Jason D. Christie, John P. Reilly, J. Palakshappa, 2018, Journal of critical care.

Epidemiology and outcomes in patients with severe sepsis admitted to the hospital wards.

Dylan S. Small, S. Bellamy, M. Mikkelsen, 2015, Journal of critical care.

Interrogating the sepsis host immune response using cytomics

N. Meyer, R. Lindell, 2023, Critical Care.

The Long Noncoding RNA Landscape in Hypoxic and Inflammatory

N. Meyer, Chenyi Xue, M. Shashaty, 2015 .

Variation in PTX3 is associated with primary graft dysfunction after lung transplantation.

P. Shah, J. Orens, J. Belperio, 2012, American journal of respiratory and critical care medicine.

Circulating heparan sulfate fragments mediate septic cognitive dysfunction

R. Linhardt, Fuming Zhang, Jian Liu, 2019, The Journal of clinical investigation.

Severe Impairment of Microcirculatory Perfused Vessel Density Is Associated With Postoperative Lactate and Acute Organ Injury After Cardiac Surgery.

B. Abella, J. Bakker, M. Acker, 2020, Journal of cardiothoracic and vascular anesthesia.

NIH Workshop Report: E-cigarette or Vaping Product Use Associated Lung Injury (EVALI): Developing a Research Agenda.

M. Goniewicz, P. Shields, R. Strongin, 2020, American journal of respiratory and critical care medicine.

Covid-19 controversies: the tocilizumab chapter

N. Meyer, E. McCreary, 2021, BMJ.

Genetics of Acute Respiratory Distress Syndrome: Pathways to Precision.

N. Meyer, H. Giannini, 2021, Critical care clinics.

ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis.

R. Gallop, M. Reilly, J. Christie, 2014, Chest.

von Willebrand factor and angiopoietin-2: toward an acute lung injury endothelial endophenotype?

J. Christie, N. Meyer, 2012, Critical care medicine.

Multivariate indicators of disease severity in COVID-19

M. Betts, N. Meyer, Wail M. Hassan, 2023, Scientific Reports.

Lower serum endocan levels are associated with the development of acute lung injury after major trauma.

A. Localio, S. Bellamy, S. Albelda, 2009, Journal of critical care.

Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness

C. Robinson-Cohen, D. Christiani, M. Wurfel, 2021, Critical care medicine.

IL1RN coding variant is associated with lower risk of acute respiratory distress syndrome and increased plasma IL-1 receptor antagonist.

Mingyao Li, R. Gallop, G. O’Keefe, 2013, American journal of respiratory and critical care medicine.

A cortactin CTTN coding SNP contributes to lung vascular permeability and inflammatory disease severity in African descent subjects.

E. Letsiou, C. Bime, Xiaoguang Sun, 2022, Translational research : the journal of laboratory and clinical medicine.

The Next Generation of ALI Genetics: Insights into Pathophysiology

J. Christie, N. Meyer, 2011 .

Role Of Ubiquitin Proteasome Pathway Activation In Akt Signaling In VILI-challenged GADD45a-/- Mice

S. Dudek, N. Meyer, S. Sammani, 2010, ATS 2010.

Report of the first seven agents in the I-SPY COVID trial: a phase 2, open label, adaptive platform randomised controlled trial

L. Esserman, R. Wahab, R. Wunderink, 2023, eClinicalMedicine.

Extracellular superoxide dismutase haplotypes and acute lung injury: reading into the genome to understand mortality?

J. Christie, N. Meyer, 2009, American journal of respiratory and critical care medicine.

Deep learning to detect acute respiratory distress syndrome on chest radiographs: a retrospective study with external validation

J. McSparron, K. Ward, M. Sjoding, 2021, The Lancet. Digital health.

Plasma insulin-like growth factor binding protein-7 (IGFBP-7) contributes causally to ARDS 28-day mortality: evidence from multi-stage Mendelian randomization.

D. Christiani, Feng Chen, L. Su, 2020, Chest.

Human red blood cells express the RNA sensor TLR7 and bind viral RNA

N. Yehya, N. Meyer, K. Jurado, 2022, bioRxiv.

Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination

A. Ogdie, E. Wherry, A. Greenplate, 2021, Critical Care Explorations.

Myeloperoxidase-derived 2-chlorofatty acids contribute to human sepsis mortality via acute respiratory distress syndrome.

S. Hazen, D. Ford, J. Christie, 2017, JCI insight.

The relationship between vitamin C or thiamine levels and outcomes for severe sepsis patients admitted to the ICU

J. Hollander, M. Mikkelsen, D. Gaieski, 2021, Scientific Reports.

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

Arthur S Slutsky, D. Brodie, J. Laffey, 2023, Intensive Care Medicine.

Neutrophil Aggregates and Elastin Degradation Compromise Lung Architecture in Fatal COVID-19

G. Bowlin, M. Radic, R. Bilyy, 2023 .

33: TIMING OF ONSET PHENOTYPES OF THE ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AFTER SEVERE TRAUMA

S. Bellamy, L. Ware, A. May, 2012 .

Early Hypotension, Severity Of Thoracic Trauma, And Blood Transfusion Are Associated With An Early Onset Endophenotype Of Acute Lung Injury After Major Trauma

A. Localio, R. Gallop, S. Bellamy, 2012, ATS 2012.

Patients’ Perspectives on Life and Recovery 1 Year After COVID-19 Hospitalization

M. Harhay, Michael Ward, N. Meyer, 2023, Journal of General Internal Medicine.

Elevation of Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries

H. Hakonarson, J. Qu, T. Miano, 2021, medRxiv.

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection Anderson et al

D. Rader, J. Weaver, M. Betts, 2021 .

Failure of TRPC6 inhibition to prevent COVID-19 deterioration: more questions than answers

N. Meyer, Elizabeth Levy, 2023, Thorax.

SNPing Away at the Genetic Risk for Acute Kidney Injury.

N. Meyer, 2017, American journal of respiratory and critical care medicine.

IL1RN Polymorphism Is Associated With Lower Risk Of Acute Lung Injury In Two Separate At-Risk Populations

H. Hakonarson, A. Localio, Mingyao Li, 2010, ATS 2010.

Large Scale Genotyping in an African American Trauma Population Identifies Angiopoietin-2 Variants Associated with ALI.

A. Localio, Mingyao Li, R. Gallop, 2009, ATS 2009.

Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis

J. Balmes, M. Matthay, T. Miano, 2023, Intensive Care Medicine.

Short and Long Term Exposure to Ambient Air Pollutants and Increased Risk of Acute Respiratory Distress Syndrome in Sepsis

J. Balmes, M. Matthay, T. Miano, 2021 .

HDL Cholesterol: A “Pathogen Lipid Sink” for Sepsis?

H. Wong, N. Meyer, T. Jones, 2019, American journal of respiratory and critical care medicine.

Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation

M. J. Mitchell, J. Christie, N. Meyer, 2023, bioRxiv.

Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction.

J. Orens, L. Ware, J. Christie, 2014, American journal of respiratory and critical care medicine.

Future clinical applications of genomics for acute respiratory distress syndrome.

N. Meyer, 2013, The Lancet. Respiratory medicine.

The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis.

M. Reilly, J. Christie, N. Meyer, 2015, Clinical journal of the American Society of Nephrology : CJASN.

The Penn Medicine COVID-19 Therapeutics Committee—Reflections on a Model for Rapid Evidence Review and Dynamic Practice Recommendations During a Public Health Emergency

T. Barton, D. Pegues, P. Tebas, 2023, Open forum infectious diseases.

I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations

L. Esserman, J. Beitler, S. Gandotra, 2022, BMJ Open.

Multivariate indicators of disease severity in COVID-19

M. Betts, N. Meyer, Wail M. Hassan, 2023, Scientific Reports.

Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome.

N. Meyer, C. Calfee, P. Sinha, 2022, Annual review of medicine.