A. Welcher

发表

Multi-omics: Differential expression of IFN-γ results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases.

A. Dzutsev, G. Trinchieri, M. Boedigheimer, 2020, Journal of autoimmunity.

Fatty acid binding protein is induced in neurons of the dorsal root ganglia after peripheral nerve injury

E. Shooter, A. Welcher, M. de León, 1996, Journal of neuroscience research.

Interactions between Brain-derived Neurotrophic Factor and the TRKB Receptor

A. Welcher, E. Bures, M. Haniu, 1997, The Journal of Biological Chemistry.

Immunocytochemical localization of TrkB in the central nervous system of the adult rat

M. Radeke, A. Welcher, Q. Yan, 1997, The Journal of comparative neurology.

Purification and identification of brain-derived neurotrophic factor from human serum.

S. Radka, A. Welcher, M. Haniu, 1995, Protein expression and purification.

Interactions of neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and the NT-3.BDNF heterodimer with the extracellular domains of the TrkB and TrkC receptors.

T. Arakawa, J. Philo, A. Welcher, 1994, The Journal of biological chemistry.

B7RP-1-ICOS Interactions Are Required for Optimal Infection-Induced Expansion of CD4+ Th1 and Th2 Responses1

C. Hunter, D. Artis, E. Wilson, 2006, The Journal of Immunology.

A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U‐BIOPRED Cohorts

C. Auffray, G. Roberts, James P R Schofield, 2017, American journal of respiratory and critical care medicine.

Cloning and Characterization of the Human Megakaryocyte Growth and Development Factor (MGDF) Gene (*)

J. Shutter, S. Suggs, A. Welcher, 1995, The Journal of Biological Chemistry.

Evidence for endotoxin contamination in plastic Na+-heparin blood collection tube lots.

S. Patterson, A. Welcher, K. Kerkof, 2010, Clinical chemistry.

Human Leptin Receptor

T. Arakawa, T. Horan, A. Welcher, 1998, The Journal of Biological Chemistry.

Expression of Growth Factors and Their Receptors in the Postnatal Rat Cochlea

G. Moonen, B. Malgrange, J. Rigo, 1998, Neurochemical Research.

Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis

J. Sánchez-Guerrero, M. Boedigheimer, M. Damore, 2017, Lupus Science & Medicine.

Identification of transcriptionally regulated genes after sciatic nerve injury

E. Shooter, U. Suter, A. Welcher, 1991, Journal of neuroscience research.

Epithelial Membrane Protein-1, Peripheral Myelin Protein 22, and Lens Membrane Protein 20 Define a Novel Gene Family *

U. Suter, A. Welcher, V. Taylor, 1995, The Journal of Biological Chemistry.

A myelin protein is encoded by the homologue of a growth arrest-specific gene.

E. Shooter, U. Suter, A. Welcher, 1991, Proceedings of the National Academy of Sciences of the United States of America.

ICOS Deficiency Is Associated with a Severe Reduction of CXCR5+CD4 Germinal Center Th Cells1

A. Plebani, A. Durandy, J. Burger, 2006, The Journal of Immunology.

Comparison of neurotrophin regulation of human and rat neuropeptide Y (NPY) neurons: induction of NPY production in aggregate cultures derived from rat but not from human fetal brains

A. Welcher, H. Chute, A. Barnea, 1996, Brain Research.

CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo.

R. Flavell, T. Horan, J. Weinstock, 2009, Cellular immunology.

ICOS Costimulation Expands Th2 Immunity by Augmenting Migration of Lymphocytes to Draining Lymph Nodes1

J. Weinstock, A. Welcher, A. Sperling, 2008, The Journal of Immunology.

Draining Lymph Nodes by Augmenting Migration of Lymphocytes to ICOS Costimulation Expands Th2 Immunity

J. Weinstock, A. Welcher, R. Shilling, 2008 .

Paradoxical role of programmed death‐1 ligand 2 in Th2 immune responses in vitro and in a mouse asthma model in vivo

T. Horan, D. Fitzpatrick, A. Welcher, 2004, European journal of immunology.

Detection and processing of peripheral myelin protein PMP22 in cultured Schwann cells.

E. Shooter, R. A. Murphy, U. Suter, 1993, The Journal of biological chemistry.

IL-17 Receptor - Brodalumab, a Human Anti Psoriatic Skin by Treatment with Gene Expression Profiles Normalized in

Hugh A. Rand, D. Salinger, A. Welcher, 2014 .

Pharmacokinetic and Pharmacodynamic Relationship of AMG 811, An Anti-IFN-γ IgG1 Monoclonal Antibody, in Patients with Systemic Lupus Erythematosus

M. Boedigheimer, David A. Martin, A. Welcher, 2014, Pharmaceutical Research.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Nerve growth factor binding domain of the nerve growth factor receptor.

E. Shooter, M. Radeke, A. Welcher, 1991, Proceedings of the National Academy of Sciences of the United States of America.

A light scattering/size exclusion chromatography method for studying the stoichiometry of a protein-protein complex

T. Arakawa, J. Philo, T. Horan, 1996 .

CSMD1 Is a Novel Multiple Domain Complement-Regulatory Protein Highly Expressed in the Central Nervous System and Epithelial Tissues1

T. Horan, V. Holers, A. Welcher, 2006, The Journal of Immunology.

Chapter 32 The molecular basis of the neuropathies of mouse and human

E. Shooter, U. Suter, A. Welcher, 1995 .

Progress in the molecular understanding of hereditary peripheral neuropathies reveals new insights into the biology of the peripheral nervous system

U. Suter, A. Welcher, G. Snipes, 1993, Trends in Neurosciences.

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

M. Boedigheimer, David A. Martin, M. Damore, 2017, Arthritis & rheumatology.

A leucine-to-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse.

E. Shooter, R. Sidman, J. Moskow, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

Xin Huang, David Powers, Daniela Metz, 2006, Journal of medicinal chemistry.

Blockade of Interferon‐γ Normalizes Interferon‐Regulated Gene Expression and Serum CXCL10 Levels in Patients With Systemic Lupus Erythematosus

M. Boedigheimer, J. Buyon, M. Damore, 2015, Arthritis & rheumatology.

Neural Membrane Protein 35 (NMP35): A Novel Member of a Gene Family Which Is Highly Expressed in the Adult Nervous System

U. Suter, V. Taylor, A. Welcher, 1998, Molecular and Cellular Neuroscience.

Regulation of tissue-specific expression of alternative peripheral myelin protein-22 (PMP22) gene transcripts by two promoters.

J. Lupski, E. Shooter, P. Patel, 1994, The Journal of biological chemistry.

The gene for the peripheral myelin protein PMP–22 is a candidate for Charcot–Marie–Tooth disease type 1A

B. Trask, J. Lupski, E. Shooter, 1992, Nature Genetics.

Elevated glial brain-derived neurotrophic factor in Parkinson's diseased nigra.

A. Kingsbury, A. Welcher, G. Wilkin, 2002, Parkinsonism & related disorders.

Selective enrichment of specific DNA, cDNA and RNA sequences using biotinylated probes, avidin and copper-chelate agarose.

D. Ward, A. Welcher, A. R. Torres, 1986, Nucleic acids research.

Trembler mouse carries a point mutation in a myelin gene

E. Shooter, R. Sidman, U. Francke, 1992, Nature.

Chicken Macrophage Stimulating Protein Is a Ligand of the Receptor Protein-tyrosine Kinase Sea*

R. Wahl, J. Parsons, P. Courchesne, 1999, The Journal of Biological Chemistry.

Regulation of T cell activation and tolerance by PDL2.

Yongliang Zhang, A. Welcher, C. Kurahara, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Expressed in the Central Nervous System and Complement-Regulatory Protein Highly CSMD1 Is a Novel Multiple Domain

A. Welcher, S. Scully, H. Chute, 2017 .

CSMD 1 Is a Novel Multiple Domain Complement-Regulatory Protein Highly Expressed in the Central Nervous System and Epithelial Tissues 1

T. Horan, V. Holers, A. Welcher, 2006 .

Pharmacokinetic and Pharmacodynamic Relationship of AMG 811, An Anti-IFN-γ IgG1 Monoclonal Antibody, in Patients with Systemic Lupus Erythematosus

M. Boedigheimer, David A. Martin, A. Welcher, 2015, Pharmaceutical Research.

Analysis of the Structure and Function of the Fast Nerve Growth Factor Receptor

A. Welcher, 1993 .

Charcot-Marie-Tooth disease type 1A. Association with a spontaneous point mutation in the PMP22 gene.

J. Lupski, E. Shooter, P. Patel, 1993, The New England journal of medicine.

Neurotrophins and Time: Different Roles for TrkB Signaling in Hippocampal Long-Term Potentiation

E. Schuman, Hyejin Kang, A. Welcher, 1997, Neuron.

Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13)

E. Shooter, U. Suter, A. Welcher, 1992, The Journal of cell biology.

Regulation of T cell activation and tolerance by PDL 2

Yongliang Zhang, A. Welcher, C. Kurahara, 2006 .

Inducible Costimulator Expression Regulates the Magnitude of Th2-Mediated Airway Inflammation by Regulating the Number of Th2 Cells

J. Weinstock, A. Welcher, A. Sperling, 2009, PloS one.

Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti–IL-17 Receptor Monoclonal Antibody

Hugh A. Rand, D. Salinger, David A. Martin, 2014, The Journal of Immunology.

Cloning and Characterization of a Specific Receptor for Mouse Oncostatin M

R. Lindberg, A. Welcher, R. Cupples, 1998, Molecular and Cellular Biology.

B61 is a ligand for the ECK receptor protein-tyrosine kinase

Yosef Yarden, Tony Hunter, T. Hunter, 1994, Nature.

Yu Receptor for Mouse Oncostatin M Cloning and Characterization of a Specific

R. Lindberg, A. Welcher, R. Cupples, 1998 .

Maximizing the sensitivity and reliability of peptide identification in large‐scale proteomic experiments by harnessing multiple search engines

Leo E Bonilla, Scott D Patterson, Wen Yu, 2010, Proteomics.

Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1.

U. Suter, J. Magyar, A. Welcher, 1996, Genomics.

Molecular approaches to nerve regeneration.

E. Shooter, U. Suter, A. Welcher, 1991, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Expression of DA11, a neuronal‐injury‐induced fatty acid binding protein, coincides with axon growth and neuronal differentiation during central nervous system development

C. Molina, A. Welcher, L. Longo, 1997, Journal of Neuroscience Research.

Rapid plasmid library screening using RecA-coated biotinylated probes.

S. Weissman, D. Ward, B. Rigas, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Endogenous Brain-Derived Neurotrophic Factor and Neurotrophin-3 Antagonistically Regulate Survival of Axotomized Corticospinal Neurons In Vivo

M. Meyer, P. Mestres, L. Reichardt, 2001, The Journal of Neuroscience.

Effect of neu differentiation factor isoforms on neonatal oligodendrocyte function

A. Welcher, S. Suy, G. Devries, 1997, Journal of neuroscience research.

BDNF/NT4‐5 receptor TrkB and cadherin participate in cell‐cell adhesion

E. Shooter, A. Welcher, Huan Zhou, 1997, Journal of neuroscience research.

Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.

P. Gallant, M. Morrison, D. Elbaum, 2006, Journal of medicinal chemistry.

Inducible CO-stimulator molecule, a candidate gene for defective isotype switching, is normal in patients with hyper-IgM syndrome of unknown molecular diagnosis.

H. Ochs, E. Gambineri, A. Welcher, 2003, The Journal of allergy and clinical immunology.

Extracellular domain of neurotrophin receptor trkB: disulfide structure, N-glycosylation sites, and ligand binding.

V. Katta, A. Welcher, M. Haniu, 1995, Archives of biochemistry and biophysics.

The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor.

E. Shooter, U. Suter, S. Meakin, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Changing Patterns of Expression and Subcellular Localization of TrkB in the Developing Visual System

C. Shatz, K. Allendoerfer, M. Radeke, 1996, The Journal of Neuroscience.

cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

R. Lindberg, A. Welcher, G. M. Fox, 1995, Oncogene.

Biochemical, biophysical, and pharmacological characterization of bacterially expressed human agouti-related protein.

V. Katta, J. Philo, J. Delaney, 1998, Biochemistry.

Studies on the structure and binding properties of the cysteine-rich domain of rat low affinity nerve growth factor receptor (p75NGFR).

A. N. Baldwin, E. Shooter, A. Welcher, 1992, The Journal of biological chemistry.

Isolation of transcriptionally regulated sequences associated with neuronal and non-neuronal cell interactions.

E. Shooter, U. Suter, S. Meakin, 1992, Progress in brain research.

A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U‐BIOPRED Cohorts

C. Auffray, G. Roberts, A. Rowe, 2017, American journal of respiratory and critical care medicine.