T. Knotts

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Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling

I. Brust-Mascher, Carly Hennessey, Mariana Barboza, 2020, bioRxiv.

Metabolic Responses to Butyrate Supplementation in LF- and HF-Fed Mice Are Cohort-Dependent and Associated with Changes in Composition and Function of the Gut Microbiota

Mariana Barboza, T. Knotts, Sunhye Lee, 2020, Nutrients.

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance.

M. Birnbaum, K. Hoehn, J. Brozinick, 2007, Cell metabolism.

Lipid mediators of insulin resistance.

K. Hoehn, S. Summers, T. Knotts, 2007, Nutrition reviews.

Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARγ and Identification of TUSC5 Coding Variants in Lean and Obese Humans

Dorothy D. Sears, J. Reddy, R. McPherson, 2010, PPAR research.

A Role for Ceramide, but Not Diacylglycerol, in the Antagonism of Insulin Signal Transduction by Saturated Fatty Acids*

R. Dobrowsky, S. Summers, T. Knotts, 2003, The Journal of Biological Chemistry.

Region-Specific Cell Membrane N-Glycome of Functional Mouse Brain Areas Revealed by nanoLC-MS Analysis

C. Lebrilla, Mariana Barboza, T. Knotts, 2021, Molecular & cellular proteomics : MCP.

Increased P85α Is a Potent Negative Regulator of Skeletal Muscle Insulin Signaling and Induces in Vivo Insulin Resistance Associated with Growth Hormone Excess*

C. Kahn, L. Cantley, D. Leroith, 2005, Journal of Biological Chemistry.

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.

D. Clegg, P. Scherer, S. Summers, 2011, The Journal of clinical investigation.

Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats.

J. Newman, S. Adams, T. Knotts, 2009, American journal of physiology. Endocrinology and metabolism.

Sex‐specific alterations in whole body energetics and voluntary activity in heterozygous R163C malignant hyperthermia‐susceptible mice

P. Allen, I. Pessah, T. Knotts, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and -independent effects.

S. Adams, T. Knotts, P. Oort, 2015, American journal of physiology. Endocrinology and metabolism.

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.

S. Griffey, F. Haj, G. Cortopassi, 2017, Cell metabolism.

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.

S. Griffey, F. Haj, G. Cortopassi, 2018, Cell metabolism.

Sex differences in response to short-term high fat diet in mice

T. Knotts, H. Raybould, J. Ramsey, 2020, Physiology & Behavior.

Acylcarnitines activate proinflammatory signaling pathways.

S. Adams, T. Knotts, D. Hwang, 2014, American journal of physiology. Endocrinology and metabolism.

Blood cytokine patterns suggest a modest inflammation phenotype in subjects with long‐chain fatty acid oxidation disorders

Michael L. Blackburn, J. Vockley, S. Adams, 2019, Physiological reports.

Evaluation of the Synuclein-γ (SNCG) Gene as a PPARγ Target in Murine Adipocytes, Dorsal Root Ganglia Somatosensory Neurons, and Human Adipose Tissue

Dorothy D. Sears, D. Sears, Steven R Smith, 2015, PloS one.

Characterization of Tusc5, an adipocyte gene co-expressed in peripheral neurons

T. Baumann, S. Adams, C. Warden, 2007, Molecular and Cellular Endocrinology.

Acylcarnitines: potential implications for skeletal muscle insulin resistance

R. McPherson, S. Adams, T. Knotts, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Increased Phosphoenolpyruvate Carboxykinase Gene Expression and Steatosis during Hepatitis C Virus Subgenome Replication

S. Rahman, J. Friedman, J. Schaack, 2012, The Journal of Biological Chemistry.

A murine model of pediatric inflammatory bowel disease causes microbiota-gut-brain axis deficits in adulthood.

I. Brust-Mascher, Carly Hennessey, T. Knotts, 2020, American journal of physiology. Gastrointestinal and liver physiology.

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

D. Befroy, G. Cline, J. Rutledge, 2018, PloS one.

Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial.

O. Fiehn, S. Adams, T. Knotts, 2015, The Journal of nutrition.

The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor

N. Weigel, T. Knotts, D. McDonnell, 1998, Molecular and Cellular Biology.

Effects of obesity, energy restriction and neutering on the faecal microbiota of cats

T. Knotts, Kyoungmi Kim, D. Kieffer, 2017, British Journal of Nutrition.

Conservation Implications of Shifting Gut Microbiomes in Captive-Reared Endangered Voles Intended for Reintroduction into the Wild

T. Knotts, J. Foley, J. Ramsey, 2018, Microorganisms.

Myelin as a regulator of development of the microbiota-gut-brain axis

I. Brust-Mascher, Mariana Barboza, T. Knotts, 2020, Brain, Behavior, and Immunity.

Acylcarnitines—old actors auditioning for new roles in metabolic physiology

S. Adams, T. Knotts, Colin S. McCoin, 2015, Nature Reviews Endocrinology.

Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism

T. Knotts, M. Goodson, M. Privalsky, 2020, PloS one.

Unique plasma metabolomic signatures of individuals with inherited disorders of long-chain fatty acid oxidation

J. Vockley, S. Adams, D. Matern, 2016, Journal of Inherited Metabolic Disease.

Identification of a Phosphorylation Site in the Hinge Region of the Human Progesterone Receptor and Additional Amino-terminal Phosphorylation Sites*

D. Edwards, R. Cook, N. Weigel, 2001, The Journal of Biological Chemistry.

Progesterone Receptor Transcriptional Activity of the Human 8-Bromo-Cyclic AMP-Dependent Key Regulators of Both Ligand-and The Nuclear Corepressors NCoR and SMRT Are

T. Knotts, D. McDonnell, J. Norris, 1998 .

γ-Synuclein Is an Adipocyte-Neuron Gene Coordinately Expressed with Leptin and Increased in Human Obesity

K. Clément, V. Buchman, S. Adams, 2008, The Journal of nutrition.

Neonatal dysbiosis has long‐lasting detrimental effects on the microbiota‐gut‐brain axis

T. Knotts, M. Pusceddu, Gonzalo Rabasa, 2020, The FASEB Journal.

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.

S. Griffey, F. Haj, G. Cortopassi, 2017, Cell metabolism.

Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial.

O. Fiehn, S. Adams, T. Knotts, 2015, The Journal of nutrition.

Acylcarnitines activate proinflammatory signaling pathways.

S. Adams, T. Knotts, D. Hwang, 2014, American journal of physiology. Endocrinology and metabolism.