F. Auer

发表

An intact gut microbiome protects genetically predisposed mice against leukemia.

K. Köhrer, J. De las Rivas, A. Borkhardt, 2020, Blood.

Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology

Martin Biel, C. Wahl-Schott, M. Biel, 2015, Nature Protocols.

Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma

S. Fröhling, R. Jessberger, H. Gohlke, 2022, International journal of molecular sciences.

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID

A. Órfão, J. Rivas, A. Borkhardt, 2019, Nature Communications.

STAT3 gain-of-function mutations associated with autoimmune lymphoproliferative syndrome like disease deregulate lymphocyte apoptosis and can be targeted by BH3 mimetic compounds.

A. Borkhardt, S. Postovsky, U. Fischer, 2017, Clinical immunology.

The Larval Zebrafish Vestibular System Is a Promising Model to Understand the Role of Myelin in Neural Circuits

David Schoppik, F. Auer, 2022, Frontiers in Neuroscience.

Clusters of neuronal neurofascin prefigure the position of a subset of nodes of Ranvier along individual central nervous system axons in vivo

F. Auer, D. Lyons, Tim Czopka, 2022, Cell reports.

Clusters of neuronal Neurofascin prefigure node of Ranvier position along single axons

F. Auer, D. Lyons, Tim Czopka, 2021, bioRxiv.

Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A

A. Borkhardt, S. Izraeli, I. Lerer, 2014, Leukemia.

JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility

H. Gohlke, A. Borkhardt, O. Haas, 2019, Leukemia.

Functionally Distinct Subgroups of Oligodendrocyte Precursor Cells Integrate Neural Activity and Execute Myelin Formation

G. Castelo-Branco, E. Agirre, F. Auer, 2019, bioRxiv.

Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.

S. Constantinescu, A. Órfão, J. Rivas, 2015, Cancer discovery.

Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy.

Alba Rodriguez-Meira, A. Borkhardt, I. Sánchez-García, 2015, Seminars in cancer biology.

Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells

Stefan Pinkert, A. Borkhardt, I. Sánchez-García, 2017, Oncotarget.

The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients

A. Borkhardt, U. Fischer, Carolin Walter, 2022, International journal of cancer.

GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.

A. Borkhardt, I. Sánchez-García, F. Auer, 2016, European journal of medical genetics.

The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells

A. Borkhardt, R. Jänicke, M. Remke, 2018, Haematologica.

Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL.

A. Órfão, J. Rivas, A. Borkhardt, 2018, Cancer research.

Potential role of STAG1 mutations in genetic predisposition to childhood hematological malignancies

E. Erba, V. Massa, F. Auer, 2022, Blood Cancer Journal.

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Zhike Lu, Chuan He, Juan Du, 2019, Nature.

Plenary Paper

K. Köhrer, J. Rivas, A. Borkhardt, 2020 .

Regional BCG vaccination policy in former East- and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia

A. Borkhardt, U. Fischer, F. Auer, 2020, Leukemia.

Evidence for Myelin Sheath Remodeling in the CNS Revealed by In Vivo Imaging

F. Auer, Tim Czopka, Franziska Auer, 2018, Current Biology.

Sick Sinus Syndrome in HCN1-Deficient Mice

C. Wahl-Schott, M. Biel, E. Becirovic, 2013, Circulation.

Sick Sinus Syndrome in HCN 1-Deficient Mice Running title :

Verena, C. Wahl-Schott, M. Biel, 2013 .

Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood

A. Borkhardt, M. Dugas, M. Erlacher, 2021, International journal of molecular sciences.

Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases.

A. Borkhardt, I. González-Herrero, I. Sánchez-García, 2017, Cancer research.

Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants

A. Borkhardt, M. Takagi, K. Imai, 2022, Leukemia.

A rare PALB2 germline variant causing G2/M cell cycle arrest is associated with isolated myelosarcoma in infancy

F. Auer, J. Hauer, R. Knöfler, 2021, Molecular genetics & genomic medicine.

Clinical criteria for genetic testing in pediatric oncology show a low specificity and miss every 4th child carrying a cancer predisposition

A. Borkhardt, M. Dugas, F. Auer, 2022, medRxiv.

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Gang Xiao, Gang Huang, Miao Sun, 2019, Nature.

Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens

W. Liu, M. Jaeger, A. Borkhardt, 2023, HemaSphere.

A clinical screening tool to detect genetic cancer predisposition in pediatric oncology shows high sensitivity but can miss a substantial percentage of affected children.

E. Schröck, A. Borkhardt, M. Erlacher, 2023, Genetics in medicine : official journal of the American College of Medical Genetics.

The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia

S. Grupp, F. Auer, A. Uzozie, 2024, Leukemia.