B. Chawes

发表

Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age.

S. Sørensen, D. Nicolae, K. Bønnelykke, 2020, The Journal of allergy and clinical immunology.

Maturation of the gut microbiome and risk of asthma in childhood

S. Sørensen, M. Blaser, J. Waage, 2018, Nature Communications.

Azithromycin for episodes with asthma-like symptoms in young children aged 1–3 years: a randomised, double-blind, placebo-controlled trial

C. Pipper, K. Bønnelykke, H. Bisgaard, 2015, The Lancet Respiratory Medicine.

Applications of metabolomics in the study and management of preeclampsia: a review of the literature

S. Weiss, R. Kelly, J. Lasky-Su, 2017, Metabolomics.

A novel common variant in DCST2 is associated with length in early life and height in adulthood

David M. Evans, M. Jarvelin, L. Liang, 2014, Human molecular genetics.

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Christopher D. Brown, A. Uitterlinden, I. Ntalla, 2020, PLoS genetics.

An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma

S. Weiss, J. Celedón, C. Clish, 2018, Chest.

Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization.

H. Bisgaard, J. Stokholm, B. Chawes, 2016, The Journal of allergy and clinical immunology.

Cesarean Delivery and Body Mass Index at 6 Months and Into Childhood

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2017, Pediatrics.

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Kyle J. Gaulton, Sara M. Willems, Samuel E. Jones, 2018, Nature Genetics.

Allergic Comorbidity Is a Risk Factor for Not Attending Scheduled Outpatient Visits in Children with Asthma

B. Chawes, M. Hermansen, M. Hauerslev, 2021, Children.

High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood: Follow-up of a randomized clinical trial

K. Bønnelykke, H. Bisgaard, S. Weiss, 2021, EClinicalMedicine.

Levels of Systemic Low-grade Inflammation in Pregnant Mothers and Their Offspring are Correlated

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2019, Scientific Reports.

Neonates with reduced neonatal lung function have systemic low-grade inflammation

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2015, Journal of Allergy and Clinical Immunology.

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

David M. Evans, D. Kiel, M. Nalls, 2018, American journal of human genetics.

J. Waage, K. Bønnelykke, H. Bisgaard, 2017, American journal of respiratory and critical care medicine.

Increasing severity of early‐onset atopic dermatitis, but not late‐onset, associates with development of aeroallergen sensitization and allergic rhinitis in childhood

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2021, Allergy.

Innate IL‐23/Type 17 immune responses mediate the effect of the 17q21 locus on childhood asthma

C. Workman, K. Bønnelykke, H. Bisgaard, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

CDHR3 gene variation and childhood bronchiolitis.

R. Janssen, A. Heinzmann, J. Waage, 2017, The Journal of allergy and clinical immunology.

Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial.

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2016, JAMA.

Disagreement between skin prick test and specific IgE in young children

K. Bønnelykke, H. Bisgaard, B. Chawes, 2015, Allergy.

Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring.

J. Waage, K. Bønnelykke, H. Bisgaard, 2016, The New England journal of medicine.

Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials

J. Waage, K. Bønnelykke, H. Bisgaard, 2017, PloS one.

Environmental and Genetic Determinants of Serum 25(OH)-Vitamin D Levels during Pregnancy and Early Childhood

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2019, Children.

Prevalence and Predictors of Antibiotic Administration during Pregnancy and Birth

K. Bønnelykke, H. Bisgaard, K. Krogfelt, 2013, PloS one.

Neonatal airway immune profiles and asthma and allergy endpoints in childhood

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2021, Allergy.

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT)

L. Corbetta, O. Usmani, P. Barnes, 2016, npj Primary Care Respiratory Medicine.

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT).

L. Corbetta, O. Usmani, P. Barnes, 2016, NPJ primary care respiratory medicine.

Genetic, Clinical, and Environmental Factors Associated With Persistent Atopic Dermatitis in Childhood

J. Waage, K. Bønnelykke, H. Bisgaard, 2019, JAMA dermatology.

Airway obstruction and bronchial reactivity from age 1 month until 13 years in children with asthma: A prospective birth cohort study

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2019, PLoS medicine.

On using kernel integration by graphical LASSO to study partial correlations between heterogeneous data sets

A. Smilde, K. Bønnelykke, M. Rasmussen, 2020, Journal of Chemometrics.

Associations of 25 Hydroxyvitamin D and High Sensitivity C-reactive Protein Levels in Early Life

K. Bønnelykke, D. Hougaard, J. Lasky-Su, 2021, Nutrients.

Cross-Sectional Blood Metabolite Markers of Hypertension: A Multicohort Analysis of 44,306 Individuals from the COnsortium of METabolomics Studies

M. Mangino, K. Rexrode, K. Suhre, 2022, Metabolites.

Sensitization trajectories in childhood revealed by using a cluster analysis

H. Bisgaard, M. Wickman, M. Rasmussen, 2017, The Journal of allergy and clinical immunology.

The role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2019, European Respiratory Journal.

Atopic endotype in childhood.

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2016, The Journal of allergy and clinical immunology.

FeNO and Exercise Testing in Children at Risk of Asthma.

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2017, The journal of allergy and clinical immunology. In practice.

The systemic exposure to inhaled beclometasone/formoterol pMDI with valved holding chamber is independent of age and body size.

H. Bisgaard, P. Kuna, Dave Singh, 2015, Pulmonary pharmacology & therapeutics.

Systemic exposure to inhaled beclometasone/formoterol DPI is age and body size dependent.

H. Bisgaard, B. Chawes, A. Døssing, 2014, Respiratory medicine.

Effect of delivery device on systemic exposure to inhaled fluticasone propionate in children with asthma.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2014, British journal of clinical pharmacology.

Long‐term predictors of loss of asthma control in school‐aged well‐controlled children with mild to moderate asthma: A 5‐year follow‐up

B. Chawes, M. Hermansen, M. Hauerslev, 2021, Pediatric pulmonology.

Pharmacokinetic comparison of inhaled fixed combination vs. the free combination of beclomethasone and formoterol pMDIs in asthmatic children.

H. Bisgaard, B. Chawes, A. Døssing, 2013, British journal of clinical pharmacology.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2012, Nature Genetics.

META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS

Christian Gieger, Nicholas J Timpson, Manuel A. R. Ferreira, 2011, Nature Genetics.

High breast milk IL‐1β level is associated with reduced risk of childhood eczema

J. Waage, H. Bisgaard, B. Chawes, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Safety of High-Dose Vitamin D Supplementation Among Children Aged 0 to 6 Years

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2022, JAMA network open.

Azithromycin and high-dose vitamin D for treatment and prevention of asthma-like episodes in hospitalised preschool children: study protocol for a combined double-blind randomised controlled trial

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2022, BMJ Open.

Early life bacterial airway colonization, local immune mediator response and risk of otitis media.

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2020, Journal of medical microbiology.

The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review

Gözde Gürdeniz, B. Chawes, M. S. Schjødt, 2020, Metabolites.

Cord Blood 25(OH)-Vitamin D Deficiency and Childhood Asthma, Allergy and Eczema: The COPSAC2000 Birth Cohort Study

K. Bønnelykke, H. Bisgaard, B. Chawes, 2014, PloS one.

Sensitivity of multiple breath washout to detect mild-to-moderate asthma in adolescence.

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2019, The journal of allergy and clinical immunology. In practice.

DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high‐risk neonates

H. Hakonarson, H. Bisgaard, B. Chawes, 2015, Pediatric pulmonology.

Children with allergic and nonallergic rhinitis have a similar risk of asthma.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2010, The Journal of allergy and clinical immunology.

Elevated exhaled nitric oxide in high-risk neonates precedes transient early but not persistent wheeze.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2010, American journal of respiratory and critical care medicine.

Early but not Persistent Wheeze

H. Bisgaard, B. Chawes, M. Hermansen, 2010 .

Neonates colonized with pathogenic bacteria in the airways have a low‐grade systemic inflammation

K. Bønnelykke, H. Bisgaard, K. Krogfelt, 2018, Allergy.

Upper and lower airway patency are associated in young children.

H. Bisgaard, B. Chawes, E. Kreiner-Møller, 2010, Chest.

Cesarean section changes neonatal gut colonization.

K. Bønnelykke, H. Bisgaard, K. Krogfelt, 2016, The Journal of allergy and clinical immunology.

Increased risk of pneumonia and bronchiolitis after bacterial colonization of the airways as neonates.

H. Bisgaard, B. Chawes, N. Vissing, 2013, American journal of respiratory and critical care medicine.

Prenatal Vitamin D Supplementation to Improve Health in Offspring.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2018, JAMA pediatrics.

The developing airway and gut microbiota in early life is influenced by age of older siblings

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2022, Microbiome.

Maternal 17q21 genotype influences prenatal vitamin D effects on offspring asthma/recurrent wheeze

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2021, European Respiratory Journal.

Pathogenic bacteria colonizing the airways in asymptomatic neonates stimulates topical inflammatory mediator release.

H. Bisgaard, M. Rasmussen, K. Krogfelt, 2013, American journal of respiratory and critical care medicine.

A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2010, The Journal of allergy and clinical immunology.

Airway immune mediator levels during asthma‐like symptoms in young children and their possible role in response to azithromycin

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2020, Allergy.

Children with Asthma have Fixed Airway Obstruction through Childhood Unaffected by Exacerbations.

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2019, The journal of allergy and clinical immunology. In practice.

Birth Cohorts in Childhood Asthma: Lessons and Limitations

K. Bønnelykke, B. Chawes, G. Nicholson, 2012 .

Symptom burden of atopic dermatitis in early childhood assessed from daily monitoring of symptoms and topical steroid usage.

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2020, Journal of the American Academy of Dermatology.

Cord blood Th2‐related chemokine CCL22 levels associate with elevated total‐IgE during preschool age

K. Bønnelykke, H. Bisgaard, M. Jenmalm, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants

H. Bisgaard, S. Johnston, B. Chawes, 2012, Journal of Allergy and Clinical Immunology.

Elevated eosinophil protein X in urine from healthy neonates precedes development of atopy in the first 6 years of life.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2011, American journal of respiratory and critical care medicine.

Deep phenotyping of the unselected COPSAC2010 birth cohort study

K. Bønnelykke, H. Bisgaard, L. Lauritzen, 2013, Clinical and Experimental Allergy.

High‐dose vitamin D during pregnancy and pathway gene polymorphisms in prevention of offspring persistent wheeze

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2020, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Parent‐specific effects on risk of developing allergic sensitization and asthma in childhood

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Children Monosensitized to Can f 5 Show Different Reactions to Male and Female Dog Allergen Extract Provocation: A Randomized Controlled Trial

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2020 .

Children mono-sensitized to Can f 5 show different reactions to male- and female dog allergen extract provocation: a randomized controlled trial.

K. Bønnelykke, H. Bisgaard, B. Kristensen, 2019, The journal of allergy and clinical immunology. In practice.

Single and multiple time‐point allergic sensitization during childhood and risk of asthma by age 13

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2019, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Multiple Breath Washout for Diagnosing Asthma and Persistent Wheeze in Young Children

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2019, Annals of the American Thoracic Society.

Reduced Neonatal Lung Function Associates with Systemic Low-grade

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2017 .

Antibiotic use during pregnancy alters the commensal vaginal microbiota.

K. Bønnelykke, H. Bisgaard, B. Jacobsson, 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Fraction of exhaled nitric oxide and bronchial responsiveness are associated and continuous traits in young children independent of asthma.

K. Bønnelykke, H. Bisgaard, B. Chawes, 2012, Chest.

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

Cecilia Kim, C. Pipper, K. Bønnelykke, 2009, American journal of respiratory and critical care medicine.

Knemometry is more sensitive to systemic effects of inhaled corticosteroids in children with asthma than 24‐hour urine cortisol excretion

H. Bisgaard, B. Chawes, A. Døssing, 2017, The Journal of allergy and clinical immunology.

A clinical pharmacology study of fixed vs. free combination of inhaled beclometasone dipropionate and formoterol fumarate dry powder inhalers in asthmatic adolescents.

H. Bisgaard, B. Chawes, N. Vissing, 2014, British journal of clinical pharmacology.

Cost of Illness in Young Children: A Prospective Birth Cohort Study

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2021, Children.

Predictors of completion and outcome of exercise challenge tests in childhood asthma

B. Chawes, M. Hermansen, K. Hansen, 2020, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Cat exposure in early life decreases asthma risk from the 17q21 high‐risk variant

H. Bisgaard, J. Stokholm, B. Chawes, 2017, The Journal of allergy and clinical immunology.

Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates.

K. Bønnelykke, H. Bisgaard, S. Johnston, 2016, The Journal of infectious diseases.

Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial.

K. Bønnelykke, H. Bisgaard, J. Kühnisch, 2019, JAMA pediatrics.

Maternal Metabolome in Pregnancy and Childhood Asthma or Recurrent Wheeze in the Vitamin D Antenatal Asthma Reduction Trial

H. Bisgaard, S. Chu, R. Kelly, 2021, Metabolites.

Effect of High-Dose vs Standard-Dose Vitamin D Supplementation in Pregnancy on Bone Mineralization in Offspring Until Age 6 Years: A Prespecified Secondary Analysis of a Double-Blinded, Randomized Clinical Trial.

K. Bønnelykke, H. Bisgaard, J. Thorsen, 2020, JAMA pediatrics.

High-Dose Vitamin D Supplementation During Pregnancy and Asthma in Offspring at the Age of 6 Years

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2019, JAMA.

Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring.

H. Bisgaard, A. Litonjua, R. Kelly, 2020, The journal of allergy and clinical immunology. In practice.

Limited clinical value of exhaled volatile organic compound measurements in childhood asthma

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2018, ERJ Open Research.

4th Pediatric Allergy and Asthma Meeting (PAAM)

Manuel A. R. Ferreira, C. Gieger, D. Postma, 2016, Clinical and Translational Allergy.

Effect of perfluoroalkyl exposure in pregnancy and infancy on intrauterine and childhood growth and anthropometry. Sub study from COPSAC2010 birth cohort

K. Bønnelykke, H. Bisgaard, D. Kristensen, 2022, EBioMedicine.

Aerosol Particle Size Does Not Predict Pharmacokinetic Determined Lung Dose in Children

K. Bønnelykke, H. Bisgaard, B. Chawes, 2013, Journal of clinical pharmacology.

Analyzing postprandial metabolomics data using multiway models: A simulation study

E. Acar, A. Smilde, H. Hoefsloot, 2022, bioRxiv.

Gene editing in the context of an increasingly complex genome

M. Nesbit, L. Castellano, J. Stebbing, 2018, BMC Genomics.

Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y.

A. Litonjua, M. McGeachie, R. Kelly, 2017, The American journal of clinical nutrition.

Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma

Shiraz A. Shah, S. Sørensen, M. Blaser, 2020, Science Translational Medicine.

Allergic sensitization at school age is a systemic low‐grade inflammatory disorder

H. Bisgaard, J. Stokholm, B. Chawes, 2017, Allergy.

Low-grade disease activity in early life precedes childhood asthma and allergy.

B. Chawes, 2016, Danish medical journal.

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with asthma.

Ivana V. Yang, Andrew D. Johnson, Ryan D. Hernandez, 2019, Chest.

Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2020, Nature Communications.

Plasma 25-Hydroxyvitamin D Concentrations are Associated with Polyunsaturated Fatty Acid Metabolites in Young Children: Results from the Vitamin D Antenatal Asthma Reduction Trial

H. Bisgaard, A. Litonjua, S. Chu, 2020, Metabolites.

Maturation of the gut microbiome and risk of asthma in childhood

M. Blaser, J. Waage, K. Bønnelykke, 2018, Nature Communications.

Season of Birth Impacts the Neonatal Nasopharyngeal Microbiota

H. Bisgaard, M. Rasmussen, J. Stokholm, 2020, Children.

FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

T. Werge, T. Hansen, O. Pedersen, 2020, Nature Communications.

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

K. Verhoeckx, J. Garssen, Karine Patient, 2020, Frontiers in Immunology.

Time trends of chronic immune diseases by year of birth in Danish registries

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2021, European Journal of Epidemiology.

Childhood asthma is associated with development of type 1 diabetes and inflammatory bowel diseases: a Danish nationwide registry study

K. Bønnelykke, H. Bisgaard, Z. Andersen, 2022, Scientific reports.

Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT)

G K Crompton, P. Barnes, N. Roche, 2016, npj Primary Care Respiratory Medicine.

Outcomes reported in randomized controlled trials for mixed and non‐IgE‐mediated food allergy: Systematic review

B. Chawes, A. Schoos, W. van de Veen, 2023, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Living with Cat and Dog Increases Vaginal Colonization with E. coli in Pregnant Women

Hans Bisgaard, Bo Chawes, Jakob Stokholm, 2012, PloS one.

Upper and lower airway pathology in young children with allergic- and non-allergic rhinitis.

B. Chawes, 2011, Danish medical bulletin.

New time-saving predictor algorithm for multiple breath washout in adolescents

H. Bisgaard, B. Chawes, H. Hallas, 2016, Pediatric Research.

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age.

K. Bønnelykke, H. Bisgaard, T. Skov, 2011, The Journal of allergy and clinical immunology.

Distinct immune phenotypes in infants developing asthma during childhood

J. Waage, K. Bønnelykke, H. Bisgaard, 2020, Science Translational Medicine.

High-Dose Vitamin D Supplementation in Pregnancy and Neurodevelopment in Childhood

K. Bønnelykke, H. Bisgaard, J. Thorsen, 2020, JAMA network open.

Common variants at 12q15 and 12q24 are associated with infant head circumference

Aad van der Lugt, Xavier Estivill, Sudha Seshadri, 2013, Nature Genetics.

Susceptibility to Lower Respiratory Infections in Childhood is Associated with Perturbation of the Cytokine Response to Pathogenic Airway Bacteria

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2016, The Pediatric infectious disease journal.

Characteristics and Mechanisms of a Sphingolipid-associated Childhood Asthma Endotype.

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2021, American journal of respiratory and critical care medicine.

Null association between serum 25‐hydroxyvitamin D levels with allergic rhinitis, allergic sensitization and non‐allergic rhinitis: A Mendelian randomization study

K. Bønnelykke, B. Cheung, B. Chawes, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

25 Years of translational research in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC).

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2023, The Journal of allergy and clinical immunology.

Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS)

Matej Oresic, Ying Wang, Mir Henglin, 2019, Metabolites.

The maternal prenatal and offspring early‐life gut microbiome of childhood asthma phenotypes

H. Bisgaard, A. Litonjua, L. Bacharier, 2022, Allergy.

Neonatal metabolome of caesarean section and risk of childhood asthma

S. Sørensen, K. Bønnelykke, H. Bisgaard, 2021, European Respiratory Journal.

The Airway Microbiota Modulates Effect of Azithromycin Treatment for Episodes of Recurrent Asthma-like Symptoms in Preschool Children: A Randomized Clinical Trial.

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2021, American journal of respiratory and critical care medicine.

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

S. Sørensen, J. Waage, K. Bønnelykke, 2019, Nature Communications.

Asthma-like Symptoms in Young Children Increase the Risk of COPD.

K. Bønnelykke, H. Bisgaard, E. L. Mortensen, 2020, The Journal of allergy and clinical immunology.

In utero exposure to 25‐hydroxyvitamin D and risk of childhood asthma, wheeze, and respiratory tract infections: A meta‐analysis of birth cohort studies

H. Bisgaard, W. Cai, K. He, 2017, The Journal of allergy and clinical immunology.

Efficacy, adverse events, and inter-drug comparison of mepolizumab and reslizumab anti-IL-5 treatments of severe asthma – a systematic review and meta-analysis

B. Chawes, N. Maltbaek, D. Henriksen, 2018, European clinical respiratory journal.

Syddansk Universitet Efficacy , adverse events , and inter-drug comparison of mepolizumab and reslizumab anti-IL-5 treatments of severe asthma-a systematic review and meta-analysis

B. Chawes, D. Henriksen, U. Bødtger, 2018 .

Dilemmas, Confusion, and Misconceptions Related to Small Airways Directed Therapy

L. Corbetta, O. Usmani, P. Barnes, 2017, Chest.

Epidemiology and Risk Factors of Infection in Early Childhood

H. Bisgaard, M. Rasmussen, B. Chawes, 2018, Pediatrics.

Determinants of neurodevelopment in early childhood – results from the Copenhagen prospective studies on asthma in childhood (COPSAC2010) mother–child cohort

K. Bønnelykke, H. Bisgaard, L. Lauritzen, 2019, Acta paediatrica.

Optimal timing of influenza vaccine during pregnancy: A systematic review and meta‐analysis

N. Geard, S. Madhi, H. Bisgaard, 2019, Influenza and other respiratory viruses.

Diet‐associated vertically transferred metabolites and risk of asthma, allergy, eczema, and infections in early childhood

K. Bønnelykke, D. Hougaard, M. Rasmussen, 2023, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Vertical Transfer of Metabolites Detectable from Newborn’s Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study

K. Bønnelykke, H. Bisgaard, D. Hougaard, 2022, Metabolites.

Fish-oil supplementation in pregnancy, child metabolomics and asthma risk

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2019, EBioMedicine.

Deep phenotyping of the unselected COPSAC2010 birth cohort study

K. Bønnelykke, H. Bisgaard, L. Lauritzen, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Fish Oil and Vitamin D Supplementations in Pregnancy Protect Against Childhood Croup.

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2022, The journal of allergy and clinical immunology. In practice.

Delayed Motor Milestones Achievement in Infancy Associates with Perturbations of Amino Acids and Lipid Metabolic Pathways

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2020, Metabolites.

Expanding known viral diversity in the healthy infant gut

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2023, Nature Microbiology.

Loss of control in preschoolers with asthma is a risk factor for disease persistency

B. Chawes, M. Hermansen, Julie B Prahl, 2022, Acta paediatrica.

Risk Factors for Non-Adherence to Inhaled Corticosteroids in Preschool Children with Asthma

S. Rubak, B. Chawes, M. Hermansen, 2022, Children.

Pulmonary function testing for the diagnosis of asthma in preschool children

B. Chawes, V. Elenius, 2022, Current opinion in allergy and clinical immunology.

Assessment of adherence to asthma controllers in children and adolescents

B. Chawes, M. Hermansen, M. Marckmann, 2020, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Lung function testing and inflammation markers for wheezing preschool children: A systematic review for the EAACI Clinical Practice Recommendations on Diagnostics of Preschool Wheeze

T. Jartti, B. Chawes, M. Ruszczyński, 2020, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

T. Ahluwalia, K. Bønnelykke, H. Bisgaard, 2019, Allergy.

Applications of metabolomics in the study and management of preeclampsia: a review of the literature

R. Kelly, J. Lasky-Su, A. Wu, 2017, Metabolomics.

Urbanized microbiota in infants, immune constitution and later risk of atopic diseases.

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2020, The Journal of allergy and clinical immunology.

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels.

K. Bønnelykke, H. Bisgaard, J. Thorsen, 2017, Journal of visualized experiments : JoVE.

Height and bone mineral content after inhaled corticosteroid use in the first 6 years of life

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2022, Thorax.

Baseline 25(OH)D, timing of supplementation initiation and prenatal vitamin D supplementation efficacy to prevent offspring asthma or recurrent wheeze.

H. Bisgaard, A. Litonjua, L. Bacharier, 2023, The American journal of clinical nutrition.

Effects of prenatal nutrient supplementation and early life exposures on neurodevelopment at age 10: a randomised controlled trial - the COPSYCH study protocol

Mark B. Vestergaard, K. Bønnelykke, H. Bisgaard, 2022, BMJ Open.

Neonatal Urine Metabolic Profiling and Development of Childhood Asthma

K. Bønnelykke, H. Bisgaard, E. Baraldi, 2019, Metabolites.

Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy.

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2012, American journal of respiratory and critical care medicine.

Vaginal dysbiosis in pregnancy associates with risk of emergency cesarean section: a prospective cohort study.

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2021, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.

Matthew C. Altman, T. Werge, T. Hansen, 2022, The Journal of allergy and clinical immunology.

Omega-3 Fatty Acids Interact with DPP10 Region Genotype in Association with Childhood Atopy

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2023, Nutrients.

Indirect comparison of efficacy of dupilumab versus mepolizumab and omalizumab for severe type 2 asthma

B. Chawes, D. Henriksen, E. Andersson, 2021, ERJ Open Research.

Efficacy of omalizumab in children, adolescents, and adults with severe allergic asthma: a systematic review, meta-analysis, and call for new trials using current guidelines for assessment of severe asthma

B. Chawes, N. Maltbaek, D. Henriksen, 2020, Allergy, Asthma & Clinical Immunology.

The influence of early life exposures on the infant gut virome

Shiraz A. Shah, K. Bønnelykke, H. Bisgaard, 2023, bioRxiv.

Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

Shiraz A. Shah, S. Sørensen, K. Bønnelykke, 2020, Nature Communications.

Precision allergy: Separate allergies to male and female dogs.

K. Bønnelykke, H. Bisgaard, B. Kristensen, 2017, The journal of allergy and clinical immunology. In practice.

Elevated third trimester corticosteroid levels are associated with fewer offspring infections

Kevin M. Mendez, K. Bønnelykke, H. Bisgaard, 2023, Scientific reports.

Reduced Steroid Metabolites Identify Infection-Prone Children in Two Independent Pre-Birth Cohorts

K. Bønnelykke, H. Bisgaard, A. Litonjua, 2022, Metabolites.

High-Dose Vitamin D Supplementation in Pregnancy and Neurodevelopment in Childhood: A Prespecified Secondary Analysis of a Randomized Clinical Trial

K. Bønnelykke, H. Bisgaard, J. Thorsen, 2020 .

Reduced IL-2 response from peripheral blood mononuclear cells exposed to bacteria at 6 months of age is associated with elevated total-IgE and allergic rhinitis during the first 7 years of life

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2019, EBioMedicine.

Allergen Specificity in Specific IgE Cutoff.

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2020, JAMA pediatrics.

Prenatal tobacco exposure and risk of asthma and allergy outcomes in childhood

K. Bønnelykke, H. Bisgaard, J. Thorsen, 2021, European Respiratory Journal.

Risk factors and age-related patterns of asthma-like symptoms in early childhood.

K. Bønnelykke, H. Bisgaard, J. Thorsen, 2022, The journal of allergy and clinical immunology. In practice.

NKG2D gene variation and susceptibility to viral bronchiolitis in childhood

J. Waage, K. Bønnelykke, H. Bisgaard, 2018, Pediatric Research.

Effect of vitamin D3 supplementation during pregnancy on risk of persistent wheeze in the offspring: a randomised clinical trial

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2016 .

Dietary prevention strategies for childhood asthma

K. Bønnelykke, B. Chawes, N. Brustad, 2023, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Antibiotic exposure in infancy and development of BMI and body composition in childhood

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2019, EClinicalMedicine.

Objective assessment of levels and patterns of physical activity in preschool children

H. Bisgaard, B. Chawes, M. Sinding, 2013, Pediatric Research.

Associations of pre‐ and postnatal exposures with optic nerve status in young adults

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2023, Acta ophthalmologica.

Fish Oil Supplementation in Pregnancy Increases Gestational Age, Size for Gestational Age, and Birth Weight in Infants: A Randomized Controlled Trial.

K. Bønnelykke, H. Bisgaard, B. Jacobsson, 2018, The Journal of nutrition.

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohort

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2023, EBioMedicine.

Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial

K. Bønnelykke, H. Bisgaard, L. Howe, 2018, British Medical Journal.

Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial.

N. Rupp, H. Bisgaard, S. Szefler, 2018, The Lancet. Respiratory medicine.

Predictors of indoor fine particulate matter in infants' bedrooms in Denmark.

Ole Hertel, Hans Bisgaard, Klaus Bønnelykke, 2011, Environmental research.

Analyzing postprandial metabolomics data using multiway models: A simulation study

E. Acar, A. Smilde, H. Hoefsloot, 2023, bioRxiv.

Prevalence and predictors of antibiotic administration during pregnancy and birth.

K. Bønnelykke, H. Bisgaard, K. Krogfelt, 2013, PloS one.

Factors to Consider in Prescribing Asthma Biologic Therapies to Children.

N. Papadopoulos, W. Phipatanakul, S. Szefler, 2023, The journal of allergy and clinical immunology. In practice.

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

Hongmei, Laurent F. Thomas, M. Jarvelin, 2022, medRxiv.

Associations between Inhaled Corticosteroid in the First 6 Years of Life and Obesity Related Traits.

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2021, American journal of respiratory and critical care medicine.

VEGFA variants are associated with pre‐school lung function, but not neonatal lung function

D. Postma, J. Vonk, G. Koppelman, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation

C. Auffray, P. Howarth, K. Rabe, 2021, European Respiratory Journal.

Atopic and non-atopic effects of fish oil supplementation during pregnancy

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2023, Thorax.

Objective confirmation of asthma diagnosis, treatment adherence and patient outcomes in children and adolescents

B. Chawes, M. Hermansen, B. Chawes, 2021, Acta paediatrica.

COVID-19 lockdown, genetic ADHD susceptibility, and mental health in 10- year-old children

K. Bønnelykke, B. Glenthøj, J. Stokholm, 2023, Psychiatry Research.

Objective assessments of allergic and nonallergic rhinitis in young children

H. Bisgaard, B. Chawes, E. Kreiner-Møller, 2009, Allergy.

Gene editing in the context of an increasingly complex genome

M. Nesbit, L. Castellano, J. Stebbing, 2018, BMC Genomics.

Mar 06, 2020 Reduced IL-2 response from peripheral blood mononuclear cells exposed to bacteria at 6months of age is associated with elevated total-IgE and allergic rhinitis during the first

K. Bønnelykke, H. Bisgaard, M. Rasmussen, 2019 .

Handgrip strength associates with effort-dependent lung function measures among adolescents with and without asthma

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2023, Scientific reports.

Apr 27, 2021 FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus

T. Werge, N. Grarup, T. Ahluwalia, 2020 .

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

C. Pipper, K. Bønnelykke, H. Bisgaard, 2009, American journal of respiratory and critical care medicine.

Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization.

H. Bisgaard, J. Stokholm, B. Chawes, 2016, The Journal of allergy and clinical immunology.

Neonates with reduced neonatal lung function have systemic low-grade inflammation

K. Bønnelykke, H. Bisgaard, J. Stokholm, 2015, Journal of Allergy and Clinical Immunology.

A chemical structure and machine learning approach to assess the potential bioactivity of endogenous metabolites and their association with early-childhood hs-CRP levels

M. Lovrić, B. Chawes, I. Šunić, 2023, bioRxiv.

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Speci c E ects

Yongmei, M. Nalls, F. Rivadeneira, 2020 .

Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects.

M. Nalls, F. Rivadeneira, T. Ahluwalia, 2017 .

COVID-19 lockdown, genetic ADHD susceptibility, and mental health in 10- year-old children

K. Bønnelykke, B. Glenthøj, J. Stokholm, 2023, Psychiatry Research.

The infant gut virome is associated with preschool asthma risk independently of bacteria.

Shiraz A. Shah, K. Bønnelykke, J. Castro-Mejía, 2023, Nature medicine.

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Kyle J. Gaulton, Sara M. Willems, Samuel E. Jones, 2018, Nature Genetics.

Sphingolipid classes and the interrelationship with pediatric asthma and asthma risk factors.

K. Bønnelykke, J. Stokholm, B. Chawes, 2023, Allergy.

Maternal Diet Associates with Offspring Bone Mineralization, Fracture Risk and Enamel Defects in Childhood and Influences the Prenatal Effect of High-Dose Vitamin D Supplementation

K. Bønnelykke, J. Stokholm, B. Chawes, 2024, Nutrients.

Characterizing human postprandial metabolic response using multiway data analysis

E. Acar, A. Smilde, B. Chawes, 2023, bioRxiv.

Allergic rhinitis is associated with otitis media with effusion: a birth cohort study

P. Cayé-Thomasen, K. Bønnelykke, H. Bisgaard, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

No associations between type 1 diabetes and atopic dermatitis, allergic rhinitis, or asthma in childhood: a nationwide Danish case-cohort study

B. Chawes, J. Svensson, S. U. Thorsen, 2023, Scientific reports.

Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases

Shiraz A. Shah, K. Bønnelykke, H. Bisgaard, 2023, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.