J. Rice

发表

Use of high-content analysis and machine learning to characterize complex microbial samples via morphological analysis

Jennifer M. Petitte, Michael Doherty, Jacob Ladd, 2019, PloS one.

Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents.

Laura G. Dubois, Philip F. Hughes, J. Strachan, 2009, Journal of Medicinal Chemistry.

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90.

Philip F. Hughes, J. Veal, S. Hall, 2012, Bioorganic & medicinal chemistry letters.

Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90.

J. Veal, S. Hall, J. Rice, 2008, Bioorganic & medicinal chemistry letters.

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis.

Laura G. Dubois, J. Veal, P. Fadden, 2008, Arthritis and rheumatism.

Novel carbazole and acyl-indole antimitotics.

J. Veal, S. Hall, J. Rice, 2009, Bioorganic & medicinal chemistry letters.

The production of an active protein kinase C-delta in insect cells is greatly enhanced by the use of the basic protein promoter.

D. Burns, T. M. Gurganus, N. Rankl, 1994, Protein expression and purification.

A comparison of large-scale Sf9 insect cell growth and protein production: stirred vessel vs. airlift.

D. Burns, T. M. Gurganus, N. Rankl, 1993, BioTechniques.

The use of high-content screening for the discovery and characterization of compounds that modulate mitotic index and cell cycle progression by differing mechanisms of action.

J. Rice, A. Barabasz, Briana E. Foley, 2006, Assay and drug development technologies.

High content analysis enables high-throughput nematicide discovery screening for measurement of viability and movement behavior in response to natural product samples

Jennifer M Petitte, Mary H Lewis, Tucker K Witsil, 2019, PloS one.

High content analysis methods enable high throughput nematode discovery screening for viability and movement behavior in a multiplex sample in response to natural product treatment

Jennifer M. Petitte, Xiang Huang, J. Rice, 2018, bioRxiv.

Targeting of multiple signaling pathways by the Hsp90 inhibitor SNX-2112 in EGFR resistance models as a single agent or in combination with erlotinib.

J. Veal, P. Fadden, S. Hall, 2009, Oncology research.

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90.

Philip F. Hughes, J. Veal, S. Hall, 2012, Bioorganic & medicinal chemistry letters.