I. Bergheim

S. Bischoff, I. Bergheim, M. Gershon, 2010, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Dietary fructose and intestinal barrier: potential risk factor in the pathogenesis of nonalcoholic fatty liver disease.

I. Bergheim, Astrid Spruss, 2009, The Journal of nutritional biochemistry.

Toll‐like receptor 4 is involved in the development of fructose‐induced hepatic steatosis in mice

S. Bischoff, I. Bergheim, Astrid Spruss, 2009, Hepatology.

Plasminogen Activator Inhibitor-1 is Regulated Through Dietary Fat Intake and Heritability: Studies in Twins

A. Pfeiffer, I. Bergheim, M. Kruse, 2017, Twin Research and Human Genetics.

Effect of acute beer ingestion on the liver: studies in female mice

C. Hellerbrand, S. Bischoff, I. Bergheim, 2015, European Journal of Nutrition.

Stimulation of fat accumulation in hepatocytes by PGE2-dependent repression of hepatic lipolysis, β-oxidation and VLDL-synthesis

H. Vogel, A. Schürmann, I. Bergheim, 2012, Laboratory Investigation.

Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1.

G. Arteel, J. Luyendyk, R. Roth, 2006, Gastroenterology.

Consumption of decaffeinated coffee protects against the development of early non-alcoholic steatohepatitis: Role of intestinal barrier function

J. Fernandez-Checa, Anja Baumann, I. Bergheim, 2018, Redox biology.

Moderate alcohol consumption diminishes the development of non-alcoholic fatty liver disease (NAFLD) in ob/ob mice

I. Bergheim, Astrid Spruss, C. Degen, 2016, European Journal of Nutrition.

Expression of toll‐like receptors 1–5 but not TLR 6–10 is elevated in livers of patients with non‐alcoholic fatty liver disease

S. Bischoff, I. Bergheim, Astrid Spruss, 2015, Liver international : official journal of the International Association for the Study of the Liver.

Bifidobacterium adolescentis protects from the development of nonalcoholic steatohepatitis in a mouse model.

S. Bischoff, I. Bergheim, Astrid Spruss, 2014, The Journal of nutritional biochemistry.

Dmbt1 does not affect a Western style diet-induced liver damage in mice

S. Bischoff, I. Bergheim, J. Mollenhauer, 2013, Journal of clinical biochemistry and nutrition.

Role of the inducible nitric oxide synthase in the onset of fructose-induced steatosis in mice.

S. Bischoff, K. Uebel, I. Bergheim, 2011, Antioxidants & redox signaling.

Toll-like receptors 1-9 are elevated in livers with fructose-induced hepatic steatosis.

S. Bischoff, I. Bergheim, Astrid Spruss, 2012, The British journal of nutrition.

Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice.

S. Bischoff, I. Bergheim, Astrid Spruss, 2011, The Journal of nutritional biochemistry.

Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice.

S. Bischoff, I. Bergheim, T. Brune, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Nonalcoholic Fatty Liver Disease in Humans Is Associated with Increased Plasma Endotoxin and Plasminogen Activator Inhibitor 1 Concentrations and with Fructose Intake 1

S. Bischoff, I. Bergheim, A. Königsrainer, 2008 .

Influence of Energy Balance and Glycemic Index on Metabolic Endotoxemia in Healthy Men

N. Breusing, A. Bosy-Westphal, M. Lagerpusch, 2017, Journal of the American College of Nutrition.

Roles of Kupffer Cells in Alcoholic Liver Disease

N. Enomoto, Y. Takei, G. Arteel, 2005 .

Citrulline and Nonessential Amino Acids Prevent Fructose-Induced Nonalcoholic Fatty Liver Disease in Rats.

I. Bergheim, J. de Bandt, P. Jegatheesan, 2015, The Journal of nutrition.

Nutrition, Intestinal Permeability, and Blood Ethanol Levels Are Altered in Patients with Nonalcoholic Fatty Liver Disease (NAFLD)

S. Bischoff, I. Bergheim, Astrid Spruss, 2012, Digestive Diseases and Sciences.

Alterations of nitric oxide homeostasis as trigger of intestinal barrier dysfunction in non‐alcoholic fatty liver disease

M. Trauner, Anja Baumann, I. Bergheim, 2022, Journal of cellular and molecular medicine.

GW9662, a peroxisome proliferator-activated receptor gamma antagonist, attenuates the development of non-alcoholic fatty liver disease.

Anja Baumann, I. Bergheim, M. L. Pisarello, 2022, Metabolism: clinical and experimental.

Microbiota profiling in aging-associated inflammation and liver degeneration.

O. Witte, C. Frahm, T. Grune, 2021, International journal of medical microbiology : IJMM.

Oral Supplementation of Glutamine Attenuates the Progression of Nonalcoholic Steatohepatitis in C57BL/6J Mice.

Anja Baumann, I. Bergheim, C. Jin, 2017, The Journal of nutrition.

Female Mice Are More Susceptible to Nonalcoholic Fatty Liver Disease: Sex-Specific Regulation of the Hepatic AMP-Activated Protein Kinase-Plasminogen Activator Inhibitor 1 Cascade, but Not the Hepatic Endotoxin Response

S. Bischoff, I. Bergheim, Astrid Spruss, 2012, Molecular medicine.

Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice

S. Bischoff, I. Bergheim, Astrid Spruss, 2010, Journal of Lipid Research.

An iso-α-acid-rich extract from hops (Humulus lupulus) attenuates acute alcohol-induced liver steatosis in mice.

C. Hellerbrand, I. Bergheim, C. Jin, 2018, Nutrition.

A low fructose diet in the treatment of pediatric obesity: A pilot study

S. Bischoff, I. Bergheim, S. Wagnerberger, 2011, Pediatrics international : official journal of the Japan Pediatric Society.

Fructose-induced steatosis in mice: role of plasminogen activator inhibitor-1, microsomal triglyceride transfer protein and NKT cells

S. Bischoff, I. Bergheim, Astrid Spruss, 2011, Laboratory Investigation.

REVIEWS: CURRENT TOPICS Dietary fructose and intestinal barrier: potential risk factor in the pathogenesis of nonalcoholic fatty liver disease

I. Bergheim, Astrid Spruss, 2009 .

Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers s⃞s⃞ This article contains supplemental data in the form of 3 figures. Published, JLR Papers in Press, October 19, 2005.

P. Fritz, I. Bergheim, E. Stange, 2006, Journal of Lipid Research.

Oral intake of xanthohumol attenuates lipoteichoic acid-induced inflammatory response in human PBMCs

C. Hellerbrand, Anja Baumann, I. Bergheim, 2022, European Journal of Nutrition.

Role of retinoic acid receptors in squamous-cell carcinoma in human esophagus

C. Bode, I. Bergheim, A. Parlesak, 2005, Journal of carcinogenesis.

Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children

I. Bergheim, Anika Nier, A. J. Engstler, 2017, PloS one.

Alcoholic liver disease and exacerbation by malnutrition and infections: what animal models are currently available?

S. Dooley, P. Eagon, I. Bergheim, 2011, Annals of the New York Academy of Sciences.

Beyond the Individual -A Scoping Review and Bibliometric Mapping of Ecological Determinants of Eating Behavior in Older Adults

C. Brombach, I. Bergheim, Í. R. Montez De Sousa, 2022, Public Health Reviews.

Markers of Intestinal Permeability Are Rapidly Improved by Alcohol Withdrawal in Patients with Alcohol-Related Liver Disease

S. Mueller, I. Bergheim, Annette Brandt, 2021, Nutrients.

Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis

M. Ebert, S. Wölfl, C. Meyer, 2018, Cell Death & Disease.

Fructose, a trigger of metabolic diseases?—a narrative review

Anja Baumann, I. Bergheim, Annette Brandt, 2022, Exploration of Digestive Diseases.

A moderate weight reduction through dietary intervention decreases hepatic fat content in patients with non-alcoholic fatty liver disease (NAFLD): a pilot study

J. Machann, S. Bischoff, I. Bergheim, 2013, European Journal of Nutrition.

Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function

S. Bischoff, I. Bergheim, Astrid Spruss, 2012, Laboratory Investigation.

Lactobacillus casei Shirota protects from fructose-induced liver steatosis: a mouse model.

S. Bischoff, I. Bergheim, Astrid Spruss, 2013, The Journal of nutritional biochemistry.

Nutritional Intake and the Risk for Non-Alcoholic Fatty Liver Disease (NAFLD)

J. Schattenberg, I. Bergheim, J. Schattenberg, 2019, Nutrients.

Effects of different standard and special diets on cognition and brain mitochondrial function in mice

I. Bergheim, T. Linn, G. Eckert, 2021, Nutritional neuroscience.

Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and ‘inflammaging'

O. Witte, K. Wagner, B. Wessner, 2022, Redox biology.

Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors

J. Schattenberg, I. Bergheim, J. Menke, 2014, Cell Death and Differentiation.

Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes

H. Steinbrenner, L. Klotz, H. Sies, 2018, Redox biology.

Cinnamon Extract Improves Insulin Sensitivity in the Brain and Lowers Liver Fat in Mouse Models of Obesity

F. Schick, J. Machann, A. Schürmann, 2014, PloS one.

Cinnamon extract protects against acute alcohol-induced liver steatosis in mice.

S. Bischoff, I. Bergheim, Astrid Spruss, 2009, The Journal of nutrition.

Alcohol and retinoids.

H. Ishii, D. Crabb, C. Lieber, 2001, Alcoholism, clinical and experimental research.

Oral arginine supplementation protects female mice from the onset of non-alcoholic steatohepatitis

I. Bergheim, C. Jin, Anika Nier, 2017, Amino Acids.

Oral intake of xanthohumol attenuates lipoteichoic acid-induced inflammatory response in human PBMCs

C. Hellerbrand, Anja Baumann, I. Bergheim, 2022, European Journal of Nutrition.

Lactobacillus rhamnosus GG Protects against Non-Alcoholic Fatty Liver Disease in Mice

S. Bischoff, A. Schwiertz, I. Bergheim, 2014, PloS one.

Anti-inflammatory and antioxidant activities of Inula viscosa and Senecio anteuphorbium

I. Bergheim, J. Guigonis, K. Belhamel, 2018, Oriental Pharmacy and Experimental Medicine.

Sodium butyrate protects mice from the development of the early signs of non-alcoholic fatty liver disease: role of melatonin and lipid peroxidation

I. Bergheim, W. Vetter, C. Jin, 2016, British Journal of Nutrition.

Oral intake of chicoric acid reduces acute alcohol-induced hepatic steatosis in mice.

I. Bergheim, Astrid Spruss, Marianne Landmann, 2014, Nutrition.

Cinnamon extract inhibits degranulation and de novo synthesis of inflammatory mediators in mast cells

I. Bergheim, Y. Hagenlocher, A. Lorentz, 2013, Allergy.

Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

J. Schattenberg, I. Bergheim, C. Jin, 2015, Gut.

Adipokines and Endotoxemia Correlate with Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease (NAFLD)

J. Schattenberg, C. Labenz, I. Bergheim, 2020, Nutrients.

Midbody-Localized Aquaporin Mediates Intercellular Lumen Expansion During Early Cleavage of an Invasive Freshwater Bivalve

A. Wanninger, A. Calcino, I. Bergheim, 2022, Frontiers in Cell and Developmental Biology.

Diets rich in fructose, fat or fructose and fat alter intestinal barrier function and lead to the development of nonalcoholic fatty liver disease over time.

I. Bergheim, Astrid Spruss, O. Huber, 2015, The Journal of nutritional biochemistry.

Rapid and sensitive determination of protein-nitrotyrosine by ELISA: Application to human plasma

N. Breusing, T. Grune, I. Bergheim, 2012, Free radical research.

Short‐Term Isocaloric Intake of a Fructose‐ but not Glucose‐Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight Healthy Subjects

I. Bergheim, Anika Nier, Tony Bruns, 2019, Molecular nutrition & food research.

Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu

D. Schuppan, P. Galle, P. Simon, 2017, Cell Death & Disease.

Beneficial Effects of Vitamin D Treatment in an Obese Mouse Model of Non-Alcoholic Steatohepatitis

H. Hermanns, K. Lenaerts, I. Bergheim, 2017, Zeitschrift für Gastroenterologie.

Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury

C. Trautwein, J. Hengstler, A. Ghallab, 2020, Zeitschrift für Gastroenterologie.

Citrulline supplementation attenuates the development of non-alcoholic steatohepatitis in female mice through mechanisms involving intestinal arginase

Anja Baumann, I. Bergheim, A. Camarinha-Silva, 2021, Redox biology.

In Vitro and in Vivo Models of Non-Alcoholic Fatty Liver Disease (NAFLD)

I. Bergheim, Ina Bergheim, Giridhar Kanuri, 2013, International journal of molecular sciences.

1 Alcohol Drinking Patterns and Nutrition in Alcoholic Liver Disease

I. Bergheim, G. Kanuri, S. Wagnerberger, 2017 .

Alcohol Drinking Patterns and Nutrition in Alcoholic Liver Disease

I. Bergheim, G. Kanuri, S. Wagnerberger, 2012 .

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

C. Trautwein, J. Haybaeck, T. Longerich, 2019, Gut.

Nutritional deficiencies in German middle-class male alcohol consumers: relation to dietary intake and severity of liver disease

C. Bode, I. Bergheim, A. Parlesak, 2003, European Journal of Clinical Nutrition.

Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH)

I. Bergheim, C. Jin, A. J. Engstler, 2015, British Journal of Nutrition.

Treatment with the 5-HT3 antagonist tropisetron modulates glucose-induced obesity in mice

S. Bischoff, I. Bergheim, V. Volynets, 2009, International Journal of Obesity.

Differences in the prevalence of metabolic disorders between prepubertal boys and girls from 5 to 8 years of age

I. Bergheim, M. Hulpke-Wette, S. Wagnerberger, 2014, Acta paediatrica.

Dietary pattern and leisure time activity of overweight and normal weight children in Germany: sex-specific differences

S. Bischoff, I. Bergheim, S. Wagnerberger, 2013, Nutrition Journal.

Validation of Malnutrition Screening Tools in Liver Cirrhosis

V. Stadlbauer, A. Horvath, I. Bergheim, 2020, Nutrients.

Metformin attenuates the onset of non-alcoholic fatty liver disease and affects intestinal microbiota and barrier in small intestine

Anja Baumann, I. Bergheim, A. Camarinha-Silva, 2019, Scientific Reports.

Beer Is Less Harmful for the Liver than Plain Ethanol: Studies in Male Mice Using a Binge-Drinking Model.

I. Bergheim, Marianne Landmann, D. Ziegenhardt, 2015, Alcohol and alcoholism.

Metabolic Abnormalities in Normal Weight Children Are Associated with Increased Visceral Fat Accumulation, Elevated Plasma Endotoxin Levels and a Higher Monosaccharide Intake

Anja Baumann, I. Bergheim, Anika Nier, 2019, Nutrients.

Cytochrome P450 levels are altered in patients with esophageal squamous-cell carcinoma.

C. Bode, I. Bergheim, A. Parlesak, 2007, World journal of gastroenterology.

Anti-inflammatory and antioxidant activities of Inula viscosa and Senecio anteuphorbium

I. Bergheim, J. Guigonis, K. Belhamel, 2018, Oriental Pharmacy and Experimental Medicine.

Microbiome and Diseases: Hepatic Disorders

D. Schuppan, I. Bergheim, 2018 .

Short-Term Intake of a Fructose-, Fat- and Cholesterol-Rich Diet Causes Hepatic Steatosis in Mice: Effect of Antibiotic Treatment

I. Bergheim, C. Jin, Annette Brandt, 2017, Nutrients.

Oral citrulline supplementation protects female mice from the development of non-alcoholic fatty liver disease (NAFLD)

I. Bergheim, C. Jin, J. Bandt, 2017, European Journal of Nutrition.

Oral arginine supplementation protects female mice from the onset of non-alcoholic steatohepatitis

I. Bergheim, C. Jin, Anika Nier, 2017, Amino Acids.

Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis

C. Trautwein, N. Gassler, J. Hengstler, 2023, Nature communications.

Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis

M. Ebert, S. Wölfl, C. Meyer, 2018, Cell Death and Disease.

Relations of gut liver axis components and gut microbiota in obese children with fatty liver: A pilot study.

A. Weisz, P. Vajro, R. Tarallo, 2018, Clinics and research in hepatology and gastroenterology.

Toll-like receptor 1 as a possible target in non-alcoholic fatty liver disease

J. Schattenberg, Anja Baumann, I. Bergheim, 2021, Scientific Reports.

Critical Role of Plasminogen Activator Inhibitor-1 in Cholestatic Liver Injury and Fibrosis

G. Arteel, I. Bergheim, Luping Guo, 2006, Journal of Pharmacology and Experimental Therapeutics.

Distribution of cytochrome P450 2C, 2E1, 3A4, and 3A5 in human colon mucosa

C. Bode, I. Bergheim, A. Parlesak, 2005, BMC clinical pharmacology.

Treatment of alcoholic liver disease.

C. McClain, G. Arteel, I. Bergheim, 2005, Digestive diseases.

Treatment with alpha‐galactosylceramide protects mice from early onset of nonalcoholic steatohepatitis: Role of intestinal barrier function

I. Bergheim, C. Jin, Annette Brandt, 2017, Molecular nutrition & food research.

Gw9662, a peroxisome proliferator-activated receptor gamma antagonist, attenuates the development of non-alcoholic fatty liver disease

Anja Baumann, I. Bergheim, Anika Nier, 2020, Journal of Hepatology.

I. Bergheim, Annette Brandt, Finn Jung, 2023, Exploration of Digestive Diseases.

Fructose: a modulator of intestinal barrier function and hepatic health?

Anja Baumann, I. Bergheim, Raphaela Staltner, 2023, European Journal of Nutrition.

Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions

Anja Baumann, I. Bergheim, A. Camarinha-Silva, 2023, Cells.

Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice.

C. Trautwein, N. Gassler, K. Streetz, 2014, Journal of hepatology.

Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats.

I. Bergheim, A. Waligora-Dupriet, J. de Bandt, 2016, The British journal of nutrition.

Sex-specific differences in the development of acute alcohol-induced liver steatosis in mice.

S. Mueller, S. Bischoff, I. Bergheim, 2013, Alcohol and alcoholism.

Loss of lipopolysaccharide‐binding protein attenuates the development of diet‐induced non‐alcoholic fatty liver disease in mice

C. Trautwein, I. Bergheim, C. Jin, 2017, Journal of gastroenterology and hepatology.

Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

J. Schattenberg, I. Bergheim, C. Jin, 2015, Gut.

TNFα is a key trigger of inflammation in diet-induced non-obese MASLD in mice

Anja Baumann, I. Bergheim, Annette Brandt, 2023, Redox biology.

Oral Glutamine Supplementation Protects Female Mice from Nonalcoholic Steatohepatitis.

I. Bergheim, C. Jin, J. de Bandt, 2015, The Journal of nutrition.

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin.

C. McClain, S. Bischoff, I. Bergheim, 2008, Journal of hepatology.

Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice.

S. Bischoff, I. Bergheim, T. Brune, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Relations of gut liver axis components and gut microbiota in obese children with fatty liver: A pilot study.

A. Weisz, P. Vajro, J. Troisi, 2018, Clinics and research in hepatology and gastroenterology.

Multiple gut–liver axis abnormalities in children with obesity with and without hepatic involvement

P. Vajro, I. Bergheim, M. Boffardi, 2017, Pediatric obesity.

The Frequent Adiponutrin (PNPLA3) Variant p.Ile148Met Is Associated with Early Liver Injury: Analysis of a German Pediatric Cohort

F. Lammert, M. Krawczyk, I. Bergheim, 2015, Gastroenterology research and practice.

Citrulline and Nonessential Amino Acids Prevent Fructose-Induced Nonalcoholic Fatty Liver Disease in Rats.

I. Bergheim, J. de Bandt, P. Jegatheesan, 2015, The Journal of nutrition.