N. Kaku

发表

Effect of probiotics on gut microbiome in patients with administration of surgical antibiotic prophylaxis: A randomized controlled study.

K. Yanagihara, N. Kaku, N. Matsumoto, 2020, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Exploring the microbiota of upper respiratory tract during the development of pneumonia in a mouse model

K. Yanagihara, N. Kaku, D. Sasaki, 2019, PloS one.

Detection of SARS-CoV-2 using qRT-PCR in saliva obtained from asymptomatic or mild COVID-19 patients, comparative analysis with matched nasopharyngeal samples

K. Morita, K. Ariyoshi, M. Tashiro, 2021, PloS one.

Performance evaluation of the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay for the detection of IMP metallo-β-lactamase activity in Enterobacteriaceae.

K. Yanagihara, N. Kaku, K. Kosai, 2018, Diagnostic microbiology and infectious disease.

Molecular and epidemiological analysis of IMP-1 metallo-β-lactamase-producing Klebsiella pneumoniae in a tertiary care hospital in Japan.

Taishi Tsubouchi, K. Yanagihara, N. Kaku, 2019, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

In Vitro Activity of Lascufloxacin against Streptococcus pneumoniae with Mutations in the Quinolone Resistance-Determining Regions

K. Yanagihara, N. Kaku, D. Sasaki, 2018, Antimicrobial Agents and Chemotherapy.

Title Simultaneous screening for JAK 2 and calreticulin gene mutations inmyeloproliferative neoplasms with high resolution melting

K. Yanagihara, N. Kaku, D. Sasaki, 2019 .

Simultaneous screening for JAK2 and calreticulin gene mutations in myeloproliferative neoplasms with high resolution melting.

K. Yanagihara, N. Kaku, D. Sasaki, 2016, Clinica chimica acta; international journal of clinical chemistry.

Detection of Legionella pneumophila serogroup 1 in blood cultures from a patient treated with tumor necrosis factor-alpha inhibitor

K. Yanagihara, M. Fukuda, N. Kaku, 2013, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Efficacy and pharmacokinetics of ME1100, a novel optimized formulation of arbekacin for inhalation, compared with amikacin in a murine model of ventilator-associated pneumonia caused by Pseudomonas aeruginosa

K. Yanagihara, N. Kaku, K. Kosai, 2016, The Journal of antimicrobial chemotherapy.

Immunomodulatory Effect of Linezolid on Methicillin-Resistant Staphylococcus aureus Supernatant-Induced MUC5AC Overexpression in Human Airway Epithelial Cells

K. Yanagihara, N. Kaku, Y. Morinaga, 2014, Antimicrobial Agents and Chemotherapy.

TNF-α inhibits the growth of Legionella pneumophila in airway epithelial cells by inducing apoptosis.

K. Yanagihara, N. Kaku, K. Kosai, 2017, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Investigation on the virulence of non-encapsulated Streptococcus pneumoniae using liquid agar pneumonia model.

M. Nahm, K. Yanagihara, N. Kaku, 2022, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Antimicrobial and immunomodulatory effects of tedizolid against methicillin-resistant Staphylococcus aureus in a murine model of hematogenous pulmonary infection.

K. Yanagihara, N. Kaku, K. Kosai, 2016, International journal of medical microbiology : IJMM.

Efficacy and safety of cefditoren pivoxil for exacerbations of chronic obstructive pulmonary disease: A prospective multicenter interventional study.

K. Yanagihara, N. Kaku, K. Kosai, 2019, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Pathogenic Effect of Prevotella intermedia on a Mouse Pneumonia Model Due to Methicillin-Resistant Staphylococcus aureus With Up-Regulated α-Hemolysin Expression

S. Konno, K. Yanagihara, N. Kaku, 2020, Frontiers in Microbiology.

Efficacy of Azithromycin in a Mouse Pneumonia Model against Hospital-Acquired Methicillin-Resistant Staphylococcus aureus

S. Konno, K. Yanagihara, N. Kaku, 2019, Antimicrobial Agents and Chemotherapy.

In vivo efficacy of biapenem with ME1071, a novel metallo-β-lactamase (MBL) inhibitor, in a murine model mimicking ventilator-associated pneumonia caused by MBL-producing Pseudomonas aeruginosa.

K. Yanagihara, N. Kaku, Y. Morinaga, 2013, International journal of antimicrobial agents.

Plasmid-Mediated AmpC β-Lactamase and Underestimation of Extended-Spectrum β-Lactamase in Cefepime-Susceptible Elevated-Ceftazidime-MIC Enterobacteriaceae Isolates.

K. Yanagihara, N. Kaku, K. Kosai, 2018, Japanese journal of infectious diseases.

The definition of healthcare-associated pneumonia (HCAP) is insufficient for the medical environment in Japan: a comparison of HCAP and nursing and healthcare-associated pneumonia (NHCAP)

K. Yanagihara, M. Fukuda, N. Kaku, 2013, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Tedizolid inhibits MUC5AC production induced by methicillin-resistant Staphylococcus aureus in human airway epithelial cells.

K. Yanagihara, N. Kaku, K. Kosai, 2017, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

In vitro and in vivo activities of piperacillin-tazobactam and meropenem at different inoculum sizes of ESBL-producing Klebsiella pneumoniae.

N. Kaku, N. Uno, H. Hasegawa, 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells.

K. Yanagihara, N. Kaku, N. Uno, 2014, Pulmonary pharmacology & therapeutics.

Azithromycin Attenuates Lung Inflammation in a Mouse Model of Ventilator-Associated Pneumonia by Multidrug-Resistant Acinetobacter baumannii

K. Yanagihara, N. Kaku, Y. Morinaga, 2013, Antimicrobial Agents and Chemotherapy.

Title : Nationwide surveillance of methicillin-resistant Staphylococcus aureus isolated from 1 bloodstream infections in Japan 2 3 Short title : Surveillance of MRSA isolated from BSI in Japan 4 5

D. Sasaki, N. Kaku, T. Miyazaki, 2021 .

Molecular epidemiology of Clostridioides difficile and risk factors for the detection of toxin gene-positive strains.

K. Yanagihara, N. Kaku, K. Kosai, 2019, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

The Effect of In Vitro Hemolysis on Measurement of Cell-Free DNA.

K. Yanagihara, N. Kaku, N. Uno, 2019, The journal of applied laboratory medicine.

Evaluation of FilmArray respiratory panel multiplex polymerase chain reaction assay for detection of pathogens in adult outpatients with acute respiratory tract infection

K. Yanagihara, N. Kaku, K. Kosai, 2018, Journal of Infection and Chemotherapy.

A novel macrolide, solithromycin suppresses mucin overexpression induced by Pseudomonas aeruginosa LPS in airway epithelial cells.

N. Kaku, K. Kosai, N. Uno, 2020, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Flow cytometry assay for the detection of single-copy DNA in human lymphocytes

K. Yanagihara, N. Kaku, N. Uno, 2020, Nucleic acids research.

Performance evaluation of the Verigene®Clostridium difficile nucleic acid test, an automated multiplex molecular testing system for detection of C. difficile toxin.

K. Yanagihara, N. Kaku, K. Kosai, 2017, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Clinical evaluation of a fully automated and high-throughput molecular testing system for detection of influenza virus

K. Yanagihara, N. Kaku, K. Kosai, 2022, Virology Journal.

A Methodology for Assessing Tumor Clonality of Adult T Cell Leukemia/Lymphoma

K. Yanagihara, N. Kaku, D. Sasaki, 2020, Molecular therapy. Methods & clinical development.

Molecular characteristics of methicillin‐resistant Staphylococcus aureus isolated from skin and soft tissue infections collected in the Japanese nationwide surveillance

Tetsuya Matsumoto, K. Yanagihara, N. Kaku, 2019, The Journal of dermatology.

Title Influence of antimicrobial regimen on decreased in-hospital mortality ofpatients with MRSA bacteremia

Koichi, K. Yanagihara, N. Kaku, 2017 .

Active Surveillance of Methicillin-Resistant Staphylococcus aureus Using a Fully Automated Molecular Test in an Emergency Medical Center.

O. Tasaki, K. Yanagihara, N. Kaku, 2015, Japanese journal of infectious diseases.

Influence of antimicrobial regimen on decreased in-hospital mortality of patients with MRSA bacteremia.

K. Yanagihara, N. Kaku, N. Uno, 2014, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Efficacy and Pharmacokinetics of the Combination of OP0595 and Cefepime in a Mouse Model of Pneumonia Caused by Extended-Spectrum-Beta-Lactamase-Producing Klebsiella pneumoniae

K. Yanagihara, N. Kaku, K. Kosai, 2017, Antimicrobial Agents and Chemotherapy.

Safety, efficacy, and analysis of key parameters after prophylactic administration of a sustained-release formulation of azithromycin in lung cancer surgery.

T. Nagayasu, Keitaro Matsumoto, K. Yanagihara, 2021, Annals of palliative medicine.

A case of intravascular large B-cell lymphoma (IVLBCL) with no abnormal findings on chest computed tomography diagnosed by random transbronchial lung biopsy.

K. Yanagihara, N. Kaku, S. Kohno, 2010, Internal medicine.

Fluoroquinolone resistance in extended‐spectrum β‐lactamase‐producing Klebsiella pneumoniae in a Japanese tertiary hospital: silent shifting to CTX‐M‐15‐producing K. pneumoniae

K. Yanagihara, N. Kaku, K. Kosai, 2017, Journal of medical microbiology.

Detection of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae using the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay.

K. Yanagihara, N. Kaku, K. Kosai, 2019, Journal of microbiological methods.

Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012: General view of the pathogens' antibacterial susceptib

M. Fujita, M. Kaku, A. Ukimura, 2017, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Strong influence of human leukocyte antigen-DP variants on response to hepatitis B vaccine in a Japanese population.

K. Yanagihara, N. Kaku, D. Sasaki, 2017, Vaccine.

Performance of anti-SARS-CoV-2 antibody testing in asymptomatic or mild COVID-19 patients: A retrospective study in outbreak on a cruise ship

K. Morita, K. Ariyoshi, S. Kohno, 2021, PloS one.

Clinical application of a ligation-independent pathway of multiplex ligation-dependent probe amplification for the determination of quinolone susceptibility of Streptococcus pneumoniae.

K. Yanagihara, N. Kaku, K. Kosai, 2016, Journal of microbiological methods.

Efficacy of meropenem and amikacin combination therapy against carbapenemase-producing Klebsiella pneumoniae mouse model of pneumonia.

K. Yanagihara, N. Kaku, K. Ota, 2020, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Evaluation of anti-SARS-CoV-2 antibody testing in asymptomatic or mild COVID-19 patients in outbreak on a cruise ship

K. Morita, K. Ariyoshi, S. Kohno, 2021, medRxiv.

[Case of pulmonary adenocarcinoma with co-existing pulmonary actinomycosis in one region of the lung].

N. Kaku, S. Kohno, H. Soda, 2009, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

Gargle sample is an effective option in a novel fully automated molecular point-of-care test for influenza: a multicenter study

K. Yanagihara, N. Kaku, H. Mukae, 2023, Virology Journal.

Title: Multicenter performance evaluation of a novel rapid molecular point-of-care test to detect influenza using nasopharyngeal swabs and gargle samples Running head: Performance of a novel rapid POC test for Flu

K. Yanagihara, N. Kaku, H. Mukae, 2022 .

Had COVID-19 spread in the community before the first confirmed case in Nagasaki, Japan?

K. Yanagihara, N. Kaku, D. Sasaki, 2021, Microbes and infection.

Evaluation of a novel rapid TRC assay for the detection of influenza using nasopharyngeal swabs and gargle samples

K. Yanagihara, N. Kaku, N. Uno, 2021, European Journal of Clinical Microbiology & Infectious Diseases.

Multicenter evaluation of molecular point-of-care testing and digital immunoassays for influenza virus A/B and respiratory syncytial virus in patients with influenza-like illness.

K. Yanagihara, N. Kaku, K. Kosai, 2021, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Pseudomonas aeruginosa Bacteremia among Immunocompetent and Immunocompromised Patients: Relation to Initial Antibiotic Therapy and Survival.

K. Yanagihara, N. Kaku, Y. Morinaga, 2016, Japanese journal of infectious diseases.

Performance evaluation of BD Phoenix™, an automated microbiology system, for the screening of IMP-producing Enterobacteriaceae.

K. Yanagihara, N. Kaku, K. Kosai, 2018, Journal of microbiological methods.

Results of the Second Questionnaire Survey on the Genetic Testing for Infectious Diseases

Tetsuya Matsumoto, K. Yanagihara, M. Nagao, 2020, Kansenshogaku zasshi.

The surveillance of colistin-resistance and mobilized colistin resistance genes in multi-drug resistant Enterobacteriaceae isolated in Japan

M. Kaku, K. Yanagihara, N. Ohmagari, 2021, International Journal of Antimicrobial Agents.

Surveillance of colistin-resistance and mcr genes in multi-drug resistant Enterobacteriaceae

N. Ohmagari, N. Kaku, K. Kosai, 2021, medRxiv.

Antimicrobial and immunomodulatory effects of tedizolid against methicillin-resistant Staphylococcus aureus in a murine model of hematogenous pulmonary infection.

K. Yanagihara, N. Kaku, K. Kosai, 2016, International journal of medical microbiology : IJMM.

Susceptibility of Clostridium species isolated in Japan to fidaxomicin and its major metabolite OP-1118.

K. Yanagihara, N. Kaku, K. Kosai, 2018, Journal of Infection and Chemotherapy.

TNF-α inhibits the growth of Legionella pneumophila in airway epithelial cells by inducing apoptosis.

K. Yanagihara, N. Kaku, K. Kosai, 2017, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Influence of antimicrobial regimen on decreased in-hospital mortality of patients with MRSA bacteremia.

K. Yanagihara, N. Kaku, N. Uno, 2014, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

A high α1-antitrypsin/interleukin-10 ratio predicts bacterial pneumonia in adults with community-acquired pneumonia: a prospective cohort study

K. Yanagihara, N. Kaku, K. Kosai, 2023, Pneumonia.