Sathish Sivaprakasam

发表

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

Huidong Shi, D. Munn, J. Lee, 2014, Immunity.

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis.

Nagendra Singh, Sathish Sivaprakasam, P. Prasad, 2016, Pharmacology & therapeutics.

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR

R. Kaufman, A. Sharma, Nagendra Singh, 2019, Nature Communications.

Drosophila INDY and Mammalian INDY: Major Differences in Transport Mechanism and Structural Features despite Mostly Similar Biological Functions

V. Ganapathy, I. Urbatsch, Sathish Sivaprakasam, 2021, Metabolites.

SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet.

V. Ganapathy, N. Moustaid‐Moussa, J. Dufour, 2021, Biochimica et biophysica acta. Molecular basis of disease.

Unconventional Functions of Amino Acid Transporters: Role in Macropinocytosis (SLC38A5/SLC38A3) and Diet-Induced Obesity/Metabolic Syndrome (SLC6A19/SLC6A14/SLC6A6)

Merin Rose Mathew, Y. Bhutia, V. Ganapathy, 2022, Biomolecules.

α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice

Y. Bhutia, V. Ganapathy, S. Ramachandran, 2021, The Biochemical journal.

Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood–brain barrier

Y. Bhutia, V. Ganapathy, Sathish Sivaprakasam, 2021, The Biochemical journal.

Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer

Y. Bhutia, V. Ganapathy, E. Babu, 2019, Asian journal of pharmaceutical sciences.

A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood–Brain Barrier Endothelial Cell Line hCMEC/D3

Y. Bhutia, V. Ganapathy, R. Rueda, 2021, Nutrients.

Hereditary hemochromatosis disrupts uric acid homeostasis and causes hyperuricemia via altered expression/activity of xanthine oxidase and ABCG2

V. Ganapathy, Sathish Sivaprakasam, Bojana Ristic, 2020, The Biochemical journal.

Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health

Y. Bhutia, V. Ganapathy, S. Ramachandran, 2017, Nutrients.

Gut Microbiome and Colon Cancer: Role of Bacterial Metabolites and Their Molecular Targets in the Host

Y. Bhutia, V. Ganapathy, Sathish Sivaprakasam, 2017, Current Colorectal Cancer Reports.

The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment

V. Ganapathy, S. Ramachandran, P. Bhattacharjee, 2020, Oncogene.

Potent Inhibition of Macropinocytosis by Niclosamide in Cancer Cells: A Novel Mechanism for the Anticancer Efficacy for the Antihelminthic

Merin Rose Mathew, Y. Bhutia, V. Ganapathy, 2023, Cancers.

Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy

V. Ganapathy, Sathish Sivaprakasam, Jin Sun, 2017, Drug delivery.

Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis.

Y. Bhutia, V. Ganapathy, Shengping Yang, 2017, Comprehensive Physiology.

SLC6A14, a Na+/Cl−-coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling

Y. Bhutia, V. Ganapathy, M. Thangaraju, 2020, The Biochemical journal.

Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions.

Y. Bhutia, V. Ganapathy, T. Boettger, 2015, The Biochemical journal.

Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu

V. Ganapathy, S. Ramachandran, Sathish Sivaprakasam, 2019, Canadian journal of gastroenterology & hepatology.

Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation

V. Ganapathy, R. Kolhe, Nagendra Singh, 2018, The Journal of Immunology.

Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues

Merin Rose Mathew, Y. Bhutia, V. Ganapathy, 2022, Bioscience reports.

Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice

V. Ganapathy, J. Colmer-Hamood, A. Hamood, 2020, The Biochemical journal.

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR

R. Kaufman, Nagendra Singh, Sathish Sivaprakasam, 2019, Nature Communications.

Binding of Citrate-Fe3+ to Plastic Culture Dishes, an Artefact Useful as a Simple Technique to Screen for New Iron Chelators

Y. Bhutia, Sathish Sivaprakasam, Yangzom D. Bhutia, 2022, International journal of molecular sciences.

Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY)

V. Ganapathy, R B Sutton, I. Urbatsch, 2020, The Biochemical journal.

RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis

B. Pace, Mingsheng Zhang, V. Ganapathy, 2015, Cell Death and Differentiation.

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis.

Nagendra Singh, Sathish Sivaprakasam, P. Prasad, 2016, Pharmacology & therapeutics.

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

Huidong Shi, D. Munn, J. Lee, 2014, Immunity.

Sigma Receptors: Novel Regulators of Iron/Heme Homeostasis and Ferroptosis

Merin Rose Mathew, Sathish Sivaprakasam, Yangzom D. Bhutia, 2023, International journal of molecular sciences.

Induction of Oxidative Stress and Ferroptosis in Triple-Negative Breast Cancer Cells by Niclosamide via Blockade of the Function and Expression of SLC38A5 and SLC7A11

Sathish Sivaprakasam, S. Sennoune, Yangzom D. Bhutia, 2024, Antioxidants.

Impact of Oncogenic Changes in p53 and KRAS on Macropinocytosis and Ferroptosis in Colon Cancer Cells and Anticancer Efficacy of Niclosamide with Differential Effects on These Two Processes

Sathish Sivaprakasam, S. Sennoune, Yangzom D. Bhutia, 2024, Cells.

Metabolic Signature of Warburg Effect in Cancer: An Effective and Obligatory Interplay between Nutrient Transporters and Catabolic/Anabolic Pathways to Promote Tumor Growth

Sathish Sivaprakasam, Yangzom D. Bhutia, Vadivel Ganapathy, 2024, Cancers.