P. Prasad

发表

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

Huidong Shi, D. Munn, J. Lee, 2014, Immunity.

Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast.

R. Blakely, V. Ganapathy, P. Prasad, 1992, Biochemistry.

SLC19: the folate/thiamine transporter family

V. Ganapathy, P. Prasad, Sylvia B. Smith, 2004, Pflügers Archiv.

Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types.

V. Ganapathy, P. Prasad, Pamela M. Martin, 2007, Investigative ophthalmology & visual science.

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis.

Nagendra Singh, Sathish Sivaprakasam, P. Prasad, 2016, Pharmacology & therapeutics.

Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells.

V. Ganapathy, P. Prasad, F. Leibach, 1994, Biochimica et biophysica acta.

Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.

V. Ganapathy, Santosh V. Thakkar, E. Babu, 2010, Biochimica et biophysica acta.

Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand.

V. Ganapathy, M. Thangaraju, P. Prasad, 2007, Investigative ophthalmology & visual science.

Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines.

V. Ganapathy, S. Miyauchi, P. Prasad, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation

M. Thangaraju, S. Manicassamy, P. Prasad, 2021, The Journal of Immunology.

Species-Specific Influence of Lithium on the Activity of SLC13A5 (NaCT): Lithium-Induced Activation Is Specific for the Transporter in Primates

Y. Bhutia, V. Ganapathy, E. Babu, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells.

V. Ganapathy, P. Prasad, W. Huang, 2001, Investigative ophthalmology & visual science.

Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells.

V. Ganapathy, P. Prasad, M. Ola, 2001, American journal of physiology. Cell physiology.

Molecular cloning of the human placental folate transporter.

V. Ganapathy, P. Prasad, S. Ramamoorthy, 1995, Biochemical and biophysical research communications.

Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.

V. Ganapathy, I. Goldman, P. Prasad, 2010, Investigative ophthalmology & visual science.

Differential Recognition of β-Lactam Antibiotics by Intestinal and Renal Peptide Transporters, PEPT 1 and PEPT 2 (*)

V. Ganapathy, M. Brandsch, P. Prasad, 1995, The Journal of Biological Chemistry.

Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.

V. Ganapathy, P. Prasad, F. Leibach, 1997, Biochimica et biophysica acta.

RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal

V. Ganapathy, S. Ramachandran, M. Thangaraju, 2020, Cancer Research.

Identity of SMCT1 (SLC5A8) as a neuron‐specific Na+‐coupled transporter for active uptake of l‐lactate and ketone bodies in the brain

V. Ganapathy, L. Zhuang, P. Prasad, 2006, Journal of neurochemistry.

Placental transporters relevant to drug distribution across the maternal-fetal interface.

V. Ganapathy, P. Prasad, F. Leibach, 2000, The Journal of pharmacology and experimental therapeutics.

Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line.

V. Ganapathy, P. Seth, P. Prasad, 1999, The Journal of pharmacology and experimental therapeutics.

Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity

S. Manicassamy, P. Prasad, A. Suryawanshi, 2020, Frontiers in Immunology.

Characterization of N 5-Methyltetrahydrofolate Uptake in Cultured Human Retinal Pigment Epithelial Cells

V. Ganapathy, Wei Huang, P. Prasad, 2005 .

Selective expression of the high-affinity isoform of the folate receptor (FR-alpha) in the human placental syncytiotrophoblast and choriocarcinoma cells.

V. Ganapathy, P. Prasad, S. Ramamoorthy, 1994, Biochimica et biophysica acta.

Vitamin B3: niacin and transcriptome analysis in relation to the GPR109A receptor

M. Thangaraju, P. Prasad, P. Rajpurohit, 2019 .

Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis

Y. Bhutia, V. Ganapathy, M. Thangaraju, 2016, Investigative ophthalmology & visual science.

Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium.

V. Ganapathy, P. Prasad, Pamela M. Martin, 2011, Investigative ophthalmology & visual science.

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).

V. Ganapathy, Y. Fei, L. Zhuang, 2005, The Biochemical journal.

Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).

V. Ganapathy, Y. Fei, L. Zhuang, 2005, The Biochemical journal.

The Relationship Between Probiotics and Dietary Fiber Consumption and Cardiovascular Health

Nagendra Singh, A. Gurav, P. Prasad, 2017 .

Transport of D-serine via the amino acid transporter ATB(0,+) expressed in the colon.

V. Ganapathy, Wei Huang, T. Nakanishi, 2002, Biochemical and biophysical research communications.

TRANSPORT OF WATER-SOLUBLE VITAMINS - A Review -

V. Ganapathy, P. Prasad, H. Frederick, 1998 .

Transplacental transport of water-soluble vitamins

V. Ganapathy, P. Prasad, F. Leibach, 1998 .

Characterization of N5-methyltetrahydrofolate uptake in cultured human retinal pigment epithelial cells.

V. Ganapathy, P. Prasad, F. Leibach, 1997, Investigative ophthalmology & visual science.

Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line

V. Ganapathy, Wei Huang, Haiping Wang, 1998 .

The Wnt–β-Catenin–IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota

M. Thangaraju, S. Manicassamy, P. Prasad, 2020, The Journal of Immunology.

GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis

V. Ganapathy, M. Thangaraju, P. Bhattacharjee, 2018, The Journal of Immunology.

Canonical Wnt Signaling in CD11c+ APCs Regulates Microbiota-Induced Inflammation and Immune Cell Homeostasis in the Colon

M. Thangaraju, S. Manicassamy, P. Prasad, 2018, The Journal of Immunology.

Stimulation of Na+/Cl--coupled opioid peptide transport system in SK-N-SH cells by L-kyotorphin, an endogenous substrate for H+-coupled peptide transporter PEPT2.

V. Ganapathy, Santosh V. Thakkar, S. Miyauchi, 2008, Drug metabolism and pharmacokinetics.

Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A.

V. Ganapathy, T. Fujita, P. Prasad, 2001, Biochimica et biophysica acta.

Role of transporters in placental transfer of drugs.

V. Ganapathy, P. Prasad, 2005, Toxicology and applied pharmacology.

Sodium-dependent high-affinity binding of carnitine to human placental brush border membranes

V. Ganapathy, P. Prasad, F. Leibach, 1996 .

Primary Structure and Functional Characteristics of a Mammalian Sodium-coupled High Affinity Dicarboxylate Transporter*

V. Ganapathy, Haiping Wang, P. Prasad, 1999, The Journal of Biological Chemistry.

The Wnt-β-catenin-IL-10 signaling axis in intestinal antigen-presenting cells protects mice from colitis-associated colon cancer in response to gut microbiota

M. Thangaraju, S. Manicassamy, P. Prasad, 2020, The Journal of Immunology.

Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta.

V. Ganapathy, P. Prasad, F. Leibach, 1999, American journal of obstetrics and gynecology.

Primary Structure, Genomic Organization, and Functional and Electrogenic Characteristics of Human System N 1, a Na+- and H+-coupled Glutamine Transporter*

V. Ganapathy, T. Nakanishi, Haiping Wang, 2000, The Journal of Biological Chemistry.

Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.

S. Barman, V. Ganapathy, S. Offermanns, 2013, Biochimica et biophysica acta.

Cloning of the Sodium-dependent, Broad-scope, Neutral Amino Acid Transporter Bo from a Human Placental Choriocarcinoma Cell Line*

V. Ganapathy, Y. Fei, T. Yang-Feng, 1996, The Journal of Biological Chemistry.

Heterologous expression systems for studying placental transporters.

V. Ganapathy, Y. Fei, P. Prasad, 2006, Methods in molecular medicine.

Sodium-dependent vitamin C transporter SVCT2: expression and function in bone marrow stromal cells and in osteogenesis.

V. Ganapathy, P. Prasad, M. Hamrick, 2013, Stem cell research.

Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+).

V. Ganapathy, P. Prasad, P. Shekhawat, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Na+- and Cl--coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes.

V. Ganapathy, T. Nakanishi, P. Prasad, 2001, The Journal of physiology.

Brief hyperglycaemia in the early pregnant rat increases fetal weight at term by stimulating placental growth and affecting placental nutrient transport

T. Powell, T. Jansson, P. Prasad, 2007, The Journal of physiology.

Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs.

L. Ferraro, S. Tanganelli, P. Prasad, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules.

P. Prasad, A. Dalpiaz, S. Manfredini, 2004, Bioorganic & medicinal chemistry.

Transporter-mediated effects of diclofenamic acid and its ascorbyl pro-drug in the in vivo neurotropic activity of ascorbyl nipecotic acid conjugate.

L. Ferraro, S. Tanganelli, P. Prasad, 2004, Journal of pharmaceutical sciences.

Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter.

V. Ganapathy, P. Prasad, V. Mahesh, 1994 .

Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter.

V. Ganapathy, P. Prasad, S. Ramamoorthy, 1993, Biochemistry.

Mouse Models of Colitis-Associated Colon Cancer.

S. Manicassamy, P. Prasad, Dan Swafford, 2021, Methods in molecular biology.

Inhibition of the H+/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP.

V. Ganapathy, Y. Fei, M. Brandsch, 1996, Biochemical and biophysical research communications.

Genetic Deletion of LRP5 and LRP6 in Macrophages Exacerbates Colitis-Associated Systemic Inflammation and Kidney Injury in Response to Intestinal Commensal Microbiota

Z. Dong, M. Thangaraju, S. Manicassamy, 2022, The Journal of Immunology.

Cloning and Expression of a b0,+-like Amino Acid Transporter Functioning as a Heterodimer with 4F2hc Instead of rBAT

V. Ganapathy, Haiping Wang, P. Prasad, 1999, The Journal of Biological Chemistry.

Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function.

V. Ganapathy, Haiping Wang, P. Prasad, 1999, Biochemical and biophysical research communications.

The amino acid transport system y+L induced in Xenopus laevis oocytes by human choriocarcinoma cell (JAR) mRNA is functionally related to the heavy chain of the 4F2 cell surface antigen.

V. Ganapathy, Y. Fei, P. Prasad, 1995, Biochemistry.

Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization.

V. Ganapathy, T. Yang-Feng, P. Prasad, 1995, Biochemical and biophysical research communications.

Cloning and functional characterization of a new subtype of the amino acid transport system N.

R. Martindale, V. Ganapathy, T. Nakanishi, 2001, American journal of physiology. Cell physiology.

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A.

V. Ganapathy, Haiping Wang, P. Prasad, 2000, Biochimica et biophysica acta.

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy.

D. Munn, V. Ganapathy, M. Thangaraju, 2008, The Biochemical journal.

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues

V. Ganapathy, P. Prasad, M. Hamrick, 2014, BMC Musculoskeletal Disorders.

Basic Science Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells

K. Wenger, V. Ganapathy, M. Thangaraju, 2013 .

Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells.

K. Wenger, V. Ganapathy, M. Thangaraju, 2013, The spine journal : official journal of the North American Spine Society.

Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.

V. Ganapathy, C. Wagner, P. Prasad, 2007, Biochimica et biophysica acta.

Molecular and functional characterization of intestinal Na(+)-dependent neutral amino acid transporter B0.

V. Ganapathy, Y. Fei, P. Prasad, 1997, The American journal of physiology.

Identification and functional assay of the interaction motifs in the partner protein OsNAR2.1 of the two-component system for high-affinity nitrate transport

V. Ganapathy, Wei Huang, T. Nakanishi, 2014, The New phytologist.

Regulation of proton‐coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate

V. Ganapathy, P. Prasad, Pamela M. Martin, 2012, Glia.

Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells.

V. Ganapathy, P. Prasad, Pamela M. Martin, 2008, Investigative ophthalmology & visual science.

Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells.

V. Ganapathy, P. Prasad, F. Leibach, 1996, Placenta.

Cloning of neutral amino acid transporter B0 from a human placental choriocarcinoma cell line

V. Ganapathy, Y. Fei, P. Prasad, 1996 .

Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond.

V. Ganapathy, M. Thangaraju, P. Prasad, 2009, Pharmacology & therapeutics.

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.

Sudha Ananth, L. Hawthorn, V. Ganapathy, 2014, Cancer research.

Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter.

V. Ganapathy, Y. Fei, P. Prasad, 1999, Archives of biochemistry and biophysics.

Human Placental Na+-dependent Multivitamin Transporter

V. Ganapathy, Wei Huang, Haiping Wang, 1999, The Journal of Biological Chemistry.

Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.

V. Ganapathy, T. Fujita, Y. Fei, 1998, The Journal of biological chemistry.

Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells.

V. Ganapathy, P. Prasad, S. Ramamoorthy, 1997, Placenta.

Cloning and Functional Expression of a cDNA Encoding a Mammalian Sodium-dependent Vitamin Transporter Mediating the Uptake of Pantothenate, Biotin, and Lipoate*

V. Ganapathy, T. Fujita, Haiping Wang, 1998, The Journal of Biological Chemistry.

Structure and function of mammalian sodium-dependent multivitamin transporter.

V. Ganapathy, P. Prasad, 2000, Current opinion in clinical nutrition and metabolic care.

Keratinocytes join forces with immune cells in the prosecution of SMVT as a "false" biotin transporter.

V. Ganapathy, P. Prasad, 2003, The Journal of investigative dermatology.

NELF is a nuclear protein involved in hypothalamic GnRH neuronal migration

Hyung-Goo Kim, W. Xiong, L. Layman, 2010, Molecular and Cellular Endocrinology.

Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family.

V. Ganapathy, Y. Fei, L. Zhuang, 2005, The Biochemical journal.

Structure, function, and genomic organization of human Na(+)-dependent high-affinity dicarboxylate transporter.

V. Ganapathy, Haiping Wang, Y. Fei, 2000, American journal of physiology. Cell physiology.

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.

V. Ganapathy, P. Seth, P. Prasad, 1999, The Journal of pharmacology and experimental therapeutics.

Placenta as a nutritional unit

V. Ganapathy, P. Prasad, Chandra R. Jones, 2004 .

Targeting the Sodium-Dependent Multivitamin Transporter (SMVT) for Improving the Oral Absorption Properties of a Retro-Inverso Tat Nonapeptide

V. Ganapathy, P. Prasad, P. Sinko, 2001, Pharmaceutical Research.

Electrogenic nature of rat sodium-dependent multivitamin transport.

V. Ganapathy, P. Prasad, F. Leibach, 2000, Biochemical and biophysical research communications.

Sodium-dependent carnitine transport in human placental choriocarcinoma cells.

V. Ganapathy, P. Prasad, S. Ramamoorthy, 1996, Biochimica et biophysica acta.

Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.

V. Ganapathy, P. Prasad, F. Leibach, 1994, Endocrinology.

Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

V. Ganapathy, Y. Fei, L. Zhuang, 2006, Pharmaceutical Research.

Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2.

V. Ganapathy, P. Prasad, Q. Ji, 2001, Experimental eye research.

Transporters and receptors for short-chain fatty acids as the molecular link between colonic bacteria and the host.

V. Ganapathy, M. Thangaraju, Nagendra Singh, 2013, Current opinion in pharmacology.

Design, synthesis and activity of ascorbic acid prodrugs of nipecotic, kynurenic and diclophenamic acids, liable to increase neurotropic activity.

L. Ferraro, S. Tanganelli, P. Prasad, 2002, Journal of medicinal chemistry.

Regulation of placental amino acid transporter activity by mammalian target of rapamycin.

Y. Kanai, T. Powell, T. Jansson, 2009, American journal of physiology. Cell physiology.

Uptake Measurements of Thyroid Hormones and Amino Acids in Cultured Cells

V. Ganapathy, P. Prasad, F. Leibach, 1996 .

Cloning and Functional Characterization of a Potential-sensitive, Polyspecific Organic Cation Transporter (OCT3) Most Abundantly Expressed in Placenta*

V. Ganapathy, Haiping Wang, Y. Fei, 1998, The Journal of Biological Chemistry.

Regulation of the human serotonin transporter by interleukin-1 beta.

V. Ganapathy, P. Prasad, S. Ramamoorthy, 1995, Biochemical and Biophysical Research Communications - BBRC.

Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1).

V. Ganapathy, Y. Fei, P. Prasad, 1996, Biochemical and biophysical research communications.

Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+).

V. Ganapathy, T. Nakanishi, P. Prasad, 2001, The Journal of clinical investigation.

Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta.

V. Ganapathy, P. Prasad, F. Leibach, 2000, Biochemical and biophysical research communications.

Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

Y. Kanai, F. Rosario, T. Powell, 2011, Endocrinology.

High‐fat diet before and during pregnancy causes marked up‐regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

T. Powell, T. Jansson, P. Prasad, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.

G. Cresci, N. Lambert, J. Mellinger, 2009, Cancer research.

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family.

V. Ganapathy, P. Prasad, F. Leibach, 1998, Biochemical and biophysical research communications.

Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

N. Lambert, V. Ganapathy, M. Thangaraju, 2010, The Journal of Biological Chemistry.

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Raja Jothi, Lirong Pei, Huidong Shi, 2015, Nature Communications.

Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

Y. Bhutia, V. Ganapathy, Shengping Yang, 2016, British journal of pharmacology.

The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy

Y. Bhutia, V. Ganapathy, E. Babu, 2014 .

Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans.

Robert Podolsky, R. Martindale, V. Ganapathy, 2005, Biochimica et biophysica acta.

Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.

V. Ganapathy, M. Thangaraju, P. Prasad, 2009, The Biochemical journal.

Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway.

O. Fiehn, Jeong-Hyeon Choi, H. Ding, 2019, Cancer research.

Human Intestinal H+/Peptide Cotransporter

M. Hediger, V. Ganapathy, Y. Fei, 1995, The Journal of Biological Chemistry.

The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function.

V. Ganapathy, M. Thangaraju, Nagendra Singh, 2013, The Biochemical journal.

SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.

V. Ganapathy, M. Thangaraju, E. Sterneck, 2006, Cancer research.

RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy

V. Ganapathy, S. Ramachandran, M. Thangaraju, 2021, Molecular Cancer Research.

Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.

Huidong Shi, Jeong-Hyeon Choi, V. Ganapathy, 2016, Cancer research.

An RPE cell line as a useful in vitro model for studying retinoic acid receptor beta: expression and affinity.

A. De Luca, P. Prasad, A. Dalpiaz, 2008, Bioscience reports.

Up-regulation of the amino acid transporter ATB(0,+) (SLC6A14) in carcinoma of the cervix.

Robert Podolsky, R. Martindale, V. Ganapathy, 2006, Gynecologic oncology.

Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages

M. Thangaraju, S. Manicassamy, P. Prasad, 2021, Frontiers in Immunology.

Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

V. Ganapathy, E. Babu, S. Ramachandran, 2011, Oncogene.

Sodium-Coupled Transport of the Short Chain Fatty Acid Butyrate by SLC5A8 and Its Relevance to Colon Cancer

G. Cresci, J. Mellinger, V. Ganapathy, 2008, Journal of Gastrointestinal Surgery.

Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood–brain barrier

P. Brust, V. Ganapathy, P. Prasad, 2003, Brain Research.

Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

Sudha Ananth, L. Hawthorn, V. Ganapathy, 2013, Molecular and Cellular Biology.

Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant.

V. Ganapathy, P. Prasad, F. Leibach, 1999, Biochimica et biophysica acta.

Exon‐Intron Structure, Analysis of Promoter Region, and Chromosomal Localization of the Human Type 1 σ Receptor Gene

V. Ganapathy, Y. Fei, T. Yang-Feng, 1998, Journal of neurochemistry.

Functional characteristics of NaS2, a placenta-specific Na+-coupled transporter for sulfate and oxyanions of the micronutrients selenium and chromium.

V. Ganapathy, Y. Fei, S. Miyauchi, 2006, Placenta.

SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter.

V. Ganapathy, P. Prasad, Pamela M. Martin, 2006, Life sciences.

Identification of the histidyl residue obligatory for the catalytic activity of the human H+/peptide cotransporters PEPT1 and PEPT2.

V. Ganapathy, Y. Fei, P. Prasad, 1997, Biochemistry.

Expression and Differential Polarization of the Reduced-folate Transporter-1 and the Folate Receptor α in Mammalian Retinal Pigment Epithelium*

V. Ganapathy, F. Sirotnak, P. Prasad, 2000, The Journal of Biological Chemistry.

Transport via SLC 5 A 8 with Subsequent Inhibition of Histone Deacetylases HDAC 1 and HDAC 3 Underlies the Antitumor Activity of 3-Bromopyruvate

M. Thangaraju, P. Prasad, S. Itagaki, 2011 .

Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3‐bromopyruvate

V. Ganapathy, M. Thangaraju, P. Prasad, 2009, Cancer.

Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A.

V. Ganapathy, P. Prasad, W. Huang, 2001, Biochimica et biophysica acta.

Differential Influence of the 4F2 Heavy Chain and the Protein Related to b0,+ Amino Acid Transport on Substrate Affinity of the Heteromeric b0,+ Amino Acid Transporter*

V. Ganapathy, Wei Huang, Jian Wang, 2000, The Journal of Biological Chemistry.

Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine.

V. Ganapathy, P. Prasad, F. Leibach, 2000, Biochimica et biophysica acta.

Circadian clocks regulate adenylyl cyclase activity rhythms in human RPE cells.

E. Frigato, C. Bertolucci, P. Prasad, 2006, Biochemical and biophysical research communications.

Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells

Elangovan Gopal, Ferdinando Palmieri, Walter Stühmer, 2010, EMBO reports.

Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function.

V. Ganapathy, P. Prasad, W. Huang, 1999, Biochemical and biophysical research communications.

Inhibition of Amino Acid Transport System A by Interleukin-1β in Trophoblasts

V. Ganapathy, P. Prasad, Radhika K Subramanian, 2005, The Journal of the Society for Gynecologic Investigation: JSGI.

Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-deficient jvs (OCTN2(-/-)) mice.

V. Ganapathy, M. Bennett, D. Matern, 2007, Molecular genetics and metabolism.

Cloning of the Human Thiamine Transporter, a Member of the Folate Transporter Family*

V. Ganapathy, P. Prasad, L. Devoe, 1999, The Journal of Biological Chemistry.

Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate.

P. Prasad, A. Dalpiaz, C. Biondi, 2007, International journal of pharmaceutics.

Sodium-coupled Monocarboxylate Transporters in Normal Tissues and in Cancer

V. Ganapathy, M. Thangaraju, S. Miyauchi, 2008, The AAPS Journal.

Biological functions of SLC5A8, a candidate tumour suppressor.

V. Ganapathy, S. Miyauchi, P. Prasad, 2005, Biochemical Society transactions.

SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer.

V. Ganapathy, S. Ramachandran, M. Thangaraju, 2011, Cancer research.

Inhibition of system A amino acid transport activity by ethanol in BeWo choriocarcinoma cells.

V. Ganapathy, P. Prasad, L. Devoe, 2002, American journal of obstetrics and gynecology.

SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer*

V. Ganapathy, E. Babu, S. Ramachandran, 2011, The Journal of Biological Chemistry.

c/ebpδ Null Mouse as a Model for the Double Knock-out of slc5a8 and slc5a12 in Kidney*

V. Ganapathy, M. Thangaraju, E. Sterneck, 2006, Journal of Biological Chemistry.

Cellular uptake of amino acids: Systems and regulation

V. Ganapathy, Katsuhisa Inoue, P. Prasad, 2003 .

Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).

V. Ganapathy, P. Prasad, C. Bridges, 2001, Biochimica et biophysica acta.

Sodium-dependent high-affinity binding of carnitine to human placental brush border membranes.

V. Ganapathy, P. Prasad, F. Leibach, 1996, Biochimica et biophysica acta.

Expression of slc5a8 in Kidney and Its Role in Na+-coupled Transport of Lactate*

V. Ganapathy, Y. Fei, L. Zhuang, 2004, Journal of Biological Chemistry.

Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N.

R. Martindale, V. Ganapathy, T. Nakanishi, 2001, Biochemical and biophysical research communications.

Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart

V. Ganapathy, P. Prasad, Sylvia B. Smith, 2003, BMC Developmental Biology.

Transplacental Gradient for o-Serine in Humans

V. Ganapathy, Wei Huang, P. Prasad, 2019 .

Serine Racemase and D-Serine Transport in Human Placenta and Evidence for a Transplacental Gradient for D-Serine in Humans

V. Ganapathy, Wei Huang, P. Prasad, 2004, The Journal of the Society for Gynecologic Investigation: JSGI.

Human placenta as a target organ for cocaine action: Interaction of cocaine with the placental serotonin transporter

V. Ganapathy, P. Prasad, V. Mahesh, 1994, Placenta.

Retinal Ganglion Cell Loss and Mild Vasculopathy in Methylene Tetrahydrofolate Reductase (Mthfr)-Deficient Mice: A Model of Mild Hyperhomocysteinemia.

R. Rozen, V. Ganapathy, S. Markand, 2015, Investigative ophthalmology & visual science.

Human Cell Culture

B. Palsson, C. Boshoff, A. Virmani, 2002, Human Cell Culture.

Molecular and Cellular Pathobiology SIRT 1 Is Essential for Oncogenic Signaling by Estrogen / Estrogen Receptor a in Breast Cancer

V. Ganapathy, S. Ramachandran, M. Thangaraju, 2011 .

Functional link between tyrosine phosphorylation and human serotonin transporter gene expression.

V. Ganapathy, P. Prasad, F. Leibach, 1997, European journal of pharmacology.

Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse.

Kebin Liu, P. Prasad, Sylvia B. Smith, 2009, Investigative ophthalmology & visual science.

Functional characterization, localization, and molecular identification of rabbit intestinal N-amino acid transporter.

V. Ganapathy, P. Saha, U. Sundaram, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Differential Modulation of Sodium- and Chloride-Dependent Opioid Peptide Transport System by Small Nonopioid Peptides and Free Amino Acids

V. Ganapathy, Santosh V. Thakkar, S. Miyauchi, 2007, Journal of Pharmacology and Experimental Therapeutics.

Functional Identification of a Novel Transport System for Endogenous and Synthetic Opioid Peptides in the Rabbit Conjunctival Epithelial Cell Line CJVE

V. Ganapathy, P. Prasad, Pamela M. Martin, 2009, Pharmaceutical Research.

Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer.

Y. Bhutia, V. Ganapathy, E. Babu, 2015, The Biochemical journal.

Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles. Transport and binding.

V. Ganapathy, P. Prasad, F. Leibach, 1992, The Journal of biological chemistry.

Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1).

V. Ganapathy, Y. Fei, P. Prasad, 1996, Biochemical and biophysical research communications.

Abstract 17: Tumor-suppressive function of SLC5A8 in renal cancer cells

K. Robertson, V. Ganapathy, M. Thangaraju, 2012 .

Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1).

V. Ganapathy, Y. Fei, P. Prasad, 1996, Biochemical and Biophysical Research Communications - BBRC.

Rapid Report

V. Ganapathy, T. Nakanishi, P. Prasad, 2001 .

Molecular and functional characterization of the intestinal amino acid transporter B

V. Ganapathy, Y. Fei, P. Prasad, 1997 .

Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

V. Ganapathy, E. Babu, S. Ramachandran, 2011, Oncogene.

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis.

Nagendra Singh, Sathish Sivaprakasam, P. Prasad, 2016, Pharmacology & therapeutics.

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

Huidong Shi, D. Munn, J. Lee, 2014, Immunity.

Use of human placenta in studies of monoamine transporters.

V. Ganapathy, P. Prasad, F. Leibach, 1998, Methods in enzymology.

High‐fat diet before and during pregnancy causes marked up‐regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice

T. Powell, T. Jansson, P. Prasad, 2009, The FASEB Journal.

Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3‐bromopyruvate

V. Ganapathy, M. Thangaraju, P. Prasad, 2009, Cancer.

Identification of a renal cell line that constitutively expresses the kidney‐sp ecific high‐affinity H+/peptide cotransporter

M. Brandsch, C. Brandsch, P. Prasad, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.