K. Kraemer

发表

Transcription-coupled nucleotide excision repair as a determinant of cisplatin sensitivity of human cells.

Y. Pommier, A. Sarasin, T. Furuta, 2002, Cancer research.

The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts.

Sikandar G. Khan, K. Kraemer, S. Emmert, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide Excision Repair Proteins Rapidly Accumulate but Fail to Persist in Human XP‐E (DDB2 Mutant) Cells

K. Kraemer, S. Emmert, Kyu-Seon Oh, 2011, Photochemistry and photobiology.

XPC initiation codon mutation in xeroderma pigmentosum patients with and without neurological symptoms.

Sikandar G. Khan, R. Schiffmann, C. Brewer, 2009, DNA repair.

Persistence of repair proteins at unrepaired DNA damage distinguishes diseases with ERCC2 (XPD) mutations: cancer‐prone xeroderma pigmentosum vs. non‐cancer‐prone trichothiodystrophy

Sikandar G. Khan, J. Jagdeo, T. Ueda, 2008, Human mutation.

Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage.

Sikandar G. Khan, K. Kraemer, Kyu-Seon Oh, 2007, DNA repair.

Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients.

Sikandar G. Khan, H. Inui, A. Sarasin, 2006, Carcinogenesis.

The human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function.

T. D. Schneider, Sikandar G. Khan, H. Inui, 2002, Nucleic acids research.

The human XPG gene: gene architecture, alternative splicing and single nucleotide polymorphisms.

T. D. Schneider, Sikandar G. Khan, K. Kraemer, 2001, Nucleic acids research.

Clinical, cellular, and molecular features of an Israeli xeroderma pigmentosum family with a frameshift mutation in the XPC gene: sun protection prolongs life.

Sikandar G. Khan, A. Frumkin, K. Kraemer, 2000, The Journal of investigative dermatology.

Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer.

H. van Steeg, K. Kraemer, 1999, Molecular medicine today.

Effect of mutations in XPD(ERCC2) on pregnancy and prenatal development in mothers of patients with trichothiodystrophy or xeroderma pigmentosum

Sikandar G. Khan, M. Tucker, A. Goldstein, 2012, European Journal of Human Genetics.

Two essential splice lariat branchpoint sequences in one intron in a xeroderma pigmentosum DNA repair gene: mutations result in reduced XPC mRNA levels that correlate with cancer risk.

Hiroki Inui, T. D. Schneider, Juliet R. Aiken, 2003, Human molecular genetics.

Phenotypic heterogeneity in the XPB DNA helicase gene (ERCC3): xeroderma pigmentosum without and with Cockayne syndrome

Sikandar G. Khan, K. Lachlan, A. Lehmann, 2006, Human mutation.

Thyroid nodules in xeroderma pigmentosum patients: a feature of premature aging

K. Kraemer, S. G. Khan, D. Tamura, 2020, Journal of Endocrinological Investigation.

Diagnosis and Treatment of Early Melanoma: NIH Consensus Development Panel on Early Melanoma

Gary S. Rogers, Natale Cascinelli, Lowell A. Goldsmith, 1992 .

Sunlight and skin cancer: another link revealed.

K. Kraemer, 1997, Proceedings of the National Academy of Sciences of the United States of America.

DYSPLASTIC NAEVI AND CUTANEOUS MELANOMA RISK

W. Clark, D. Elder, D. Guerry, 1983, The Lancet.

Familial cutaneous malignant melanoma: autosomal dominant trait possibly linked to the Rh locus.

W. Clark, D. Elder, M. Greene, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Hereditary dysplastic nevus syndrome: lymphoid cell ultraviolet hypermutability in association with increased melanoma susceptibility.

H. L. Waters, M. Greene, A. Bredberg, 1986, Cancer research.

Ultraviolet mutagenesis in a plasmid vector replicated in lymphoid cells from patient with the melanoma-prone disorder dysplastic nevus syndrome.

H. L. Waters, M. Seidman, S. Seetharam, 1989, Cancer research.

The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm.

W. Lambert, K. Kraemer, M. M. Lee, 1994, Archives of dermatology.

Xeroderma Pigmentosum: Cutaneous, Ocular, and Neurologic Abnormalities in 830 Published Cases

K. Kraemer, J. Scotto, M. M. Lee, 1987 .

Abnormal processing of transfected plasmid DNA in cells from patients with ataxia telangiectasia.

M. Poot, K. Kraemer, T. M. Rünger, 1992, Mutation research.

Use of supF, an Escherichia coli tyrosine suppressor tRNA gene, as a mutagenic target in shuttle-vector plasmids.

M. Seidman, K. Kraemer, Kenneth H. Kraemer, 1989, Mutation research.

Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin.

Shosuke Ito, Kazumasa Wakamatsu, K. Wakamatsu, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin.

R. Tarone, K. Kraemer, J. DiGiovanna, 1988, The New England journal of medicine.

Mortality‐associated immunological abnormalities in trichothiodystrophy: correlation of reduced levels of immunoglobulin and neutrophils with poor patient survival

Sikandar G. Khan, K. Oetjen, K. Kraemer, 2018, British journal of haematology.

Growth and Nutrition in Children With Trichothiodystrophy

K. Kraemer, D. Tamura, J. DiGiovanna, 2014, Journal of pediatric gastroenterology and nutrition.

High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients

Sikandar G. Khan, M. Raffeld, S. Beltaifa, 2014, Pigment cell & melanoma research.

Ocular manifestations of xeroderma pigmentosum: long-term follow-up highlights the role of DNA repair in protection from sun damage.

Sikandar G. Khan, J. Clayton, H. Inui, 2013, Ophthalmology.

One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells.

K. Kraemer, M. Protić-Sabljić, Miroslava PROTI-SABLJI, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Relationship of neurologic degeneration to genotype in three xeroderma pigmentosum group G patients.

Sikandar G. Khan, H. Inui, L. Grossman, 2002, The Journal of investigative dermatology.

Melanoma to Vitiligo: The Melanocyte in Biology & Medicine-Joint Montagna Symposium on the Biology of Skin/PanAmerican Society for Pigment Cell Research Annual Meeting.

G. Barsh, W. Pavan, M. Kulesz-Martin, 2020, The Journal of investigative dermatology.

Dysplastic nevus syndrome. Familial and sporadic precursors of cutaneous melanoma.

M. Greene, K. Kraemer, 1985, Dermatologic clinics.

Acquired precursors of cutaneous malignant melanoma. The familial dysplastic nevus syndrome.

W. Clark, D. Elder, D. Guerry, 1985, The New England journal of medicine.

Heritable genetic alterations in a xeroderma pigmentosum group G/Cockayne syndrome pedigree.

K. Kraemer, M. A. Macinnes, M. Park, 1997, Mutation research.

Xeroderma pigmentosum knockouts

K. Kraemer, 1996, The Lancet.

DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells.

I. Rapin, J. Hoeijmakers, W. Vermeulen, 1996, The Journal of investigative dermatology.

Multiple skin cancers in adults with mutations in the XP-E (DDB2) DNA repair gene.

K. Kraemer, S. Emmert, Kyu-Seon Oh, 2011, The Journal of investigative dermatology.

Ultraviolet mutagenesis in human lymphocytes: the effect of cellular transformation.

K. Kraemer, C. Parris, 1992, Experimental cell research.

Disorders of DNA repair

K. Kraemer, S. Moriwaki, 2010 .

Rare diseases provide rare insights into DNA repair pathways, TFIIH, aging and cancer center.

V. Bohr, K. Kraemer, M. Sander, 2005, DNA repair.

Genetic diversity in melanoma metastases from a patient with xeroderma pigmentosum.

E. Jaffe, M. Raffeld, K. Kraemer, 2010, The Journal of investigative dermatology.

Risk of cutaneous melanoma in dysplastic nevus syndrome types A and B.

W. Clark, D. Elder, M. Tucker, 1986, The New England journal of medicine.

A stop codon in xeroderma pigmentosum group C families in Turkey and Italy: molecular genetic evidence for a common ancestor.

Sikandar G. Khan, K. Kraemer, S. Emmert, 2001, The Journal of investigative dermatology.

Hypersensitivity of xeroderma pigmentosum cells to dietary carcinogens.

D. Whyte, K. Kraemer, M. Protić-Sabljić, 1985, Mutation research.

Analysis of point mutations in an ultraviolet-irradiated shuttle vector plasmid propagated in cells from Japanese xeroderma pigmentosum patients in complementation groups A and F.

K. Kraemer, T. Yagi, M. Sato, 1991, Cancer research.

Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates.

K. Kraemer, H. Coon, J. Robbins, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.

M. Seidman, S. Seetharam, A. Bredberg, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Chemoprevention of Skin Cancer in Xeroderma Pigmentosum

K. Kraemer, J. DiGiovanna, G. Peck, 1992, The Journal of dermatology.

Chimeric Negative Regulation of p14ARF and TBX1 by a t(9;22) Translocation Associated with Melanoma, Deafness, and DNA Repair Deficiency

Sikandar G. Khan, P. Meltzer, J. Butman, 2013, Human mutation.

Effects of 8-methoxypsoralen and ultraviolet radiation on human lymphoid cells in vitro.

H. L. Waters, R. Tarone, J. DiPaolo, 1981, The Journal of investigative dermatology.

Hereditary melanoma and the dysplastic nevus syndrome: the risk of cancers other than melanoma.

W. Clark, D. Elder, M. Greene, 1987, Journal of the American Academy of Dermatology.

Assessment of Human Lymphoid Cell Damage Induced by Therapeutic Levels of 8-Methoxypsoralen and Long Wavelength Ultraviolet Radiation In Vitro

K. Kraemer, 1983 .

Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells.

D. Brash, M. Seidman, S. Seetharam, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The nucleosome‐binding protein HMGN2 modulates global genome repair

M. Bustin, T. Ueda, K. Kraemer, 2009, The FEBS journal.

UV light-induced cyclobutane pyrimidine dimers are mutagenic in mammalian cells

P. Munson, K. Dixon, K. Kraemer, 1986, Molecular and cellular biology.

Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients

J. Egly, T. Ueda, K. Kraemer, 2009, The Journal of experimental medicine.

Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome

K. Kraemer, S. Emmert, 2013, The Journal of investigative dermatology.

Colony-forming ability of ultraviolet-irradiated xeroderma pigmentosum fibroblasts from different DNA repair complementation groups.

K. Kraemer, J. Robbins, A. Andrews, 1976, Biochimica et biophysica acta.

Five complementation groups in xeroderma pigmentosum.

D. Bootsma, K. Kraemer, J. Robbins, 1975, Mutation research.

DNA repair and mutagenesis in Werner syndrome

G. Dianov, V. Bohr, M. Seidman, 2001, Environmental and molecular mutagenesis.

Evidence for defective repair of cyclobutane pyrimidine dimers with normal repair of other DNA photoproducts in a transcriptionally active gene transfected into Cockayne syndrome cells.

R. Tarone, K. Kraemer, J. Robbins, 1991, Mutation research.

Cockayne syndrome and xeroderma pigmentosum

I. Rapin, K. Kraemer, J. Robbins, 2000, Neurology.

Impaired interferon production and natural killer cell activation in patients with the skin cancer-prone disorder, xeroderma pigmentosum.

H. Kenneth, K. Kraemer, Abin Varghese Thomas, 1993, The Journal of clinical investigation.

Ultraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal.

K. Kraemer, C. Parris, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum lymphoblastoid cells and fibroblasts.

H. L. Waters, M. Seidman, S. Seetharam, 1991, Mutation research.

Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosum.

M. Seidman, S. Seetharam, K. Kraemer, 1987, The Journal of clinical investigation.

Impaired ultraviolet-B-induced cytokine induction in xeroderma pigmentosum fibroblasts.

P. Amerio, K. Kraemer, B. Wang, 2001, The Journal of investigative dermatology.

To determine the contribution of a human DNA repair gene, ERCC2 (XPD), to mutagenesis in human cells, two ERCC2 (XPD).transformed xeroderma pigmentosum complementation group

L. Prakash, M. Seidman, K. Kraemer, 2006 .

Detection of ataxia telangiectasia heterozygous cell lines by postirradiation cumulative labeling index: measurements with coded samples.

Y. Shiloh, J. Little, H. Nagasawa, 1987, Cancer research.

Cockayne syndrome, MEN1, and genomic variants: Exome sequencing is changing our view of the genetic landscape

Sikandar G. Khan, K. Kraemer, D. Tamura, 2021, Pediatric dermatology.

Pembrolizumab treatment of a patient with xeroderma pigmentosum with disseminated melanoma and multiple nonmelanoma skin cancers

K. Kraemer, D. Tamura, S. G. Khan, 2018, The British journal of dermatology.

Repair of UV photolesions in xeroderma pigmentosum group C cells induced by translational readthrough of premature termination codons

Sikandar G. Khan, R. Gatti, K. Kraemer, 2013, Proceedings of the National Academy of Sciences.

A potential laboratory test for dysplastic nevus syndrome: ultraviolet hypermutability of a shuttle vector plasmid.

R. Tarone, K. Kraemer, S. Moriwaki, 1994, The Journal of investigative dermatology.

Ultraviolet hypermutability of a shuttle vector propagated in xeroderma pigmentosum variant cells.

H. L. Waters, M. Seidman, S. Seetharam, 1993, The Journal of investigative dermatology.

Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: A complex genotype–phenotype relationship

R. Schiffmann, N. Patronas, K. Kraemer, 2007, Neuroscience.

DNA REPAIR-DEFICIENT HUMAN DISEASES

K. Kraemer, 1992 .

Topical enzyme therapy for skin diseases?

K. Kraemer, J. DiGiovanna, 2002, Journal of the American Academy of Dermatology.

Unexpected occurrence of xeroderma pigmentosum in an uncle and nephew.

Sikandar G. Khan, R. Schiffmann, A. Paller, 2009, Archives of dermatology.

Xeroderma pigmentosum – bridging a gap between clinic and laboratory

K. Kraemer, Shinjiro Moriwaki, 2001, Photodermatology, photoimmunology & photomedicine.

Xeroderma pigmentosum knockout mice: an immunologic tale.

K. Kraemer, 1996, The Journal of investigative dermatology.

REDUCED REPAIR OF NON‐DIMER PHOTOPRODUCTS IN A GENE TRANSFECTED INTO XERODERMA PIGMENTOSUM CELLS

K. Kraemer, M. Protić-Sabljić, 1986, Photochemistry and photobiology.

Xeroderma pigmentosum long-term lymphoid lines with increased ultraviolet sensitivity.

K. Kraemer, D. Buell, J. Robbins, 1974, Journal of the National Cancer Institute.

NRAS hypermutability in familial melanoma with CDKN2A mutations--cause and effect?

K. Kraemer, 2003, Journal of the National Cancer Institute.

Hypoglycinaemia and psychomotor delay in a child with xeroderma pigmentosum

K. Kraemer, D. Whiteman, H. Levy, 1999, Journal of Inherited Metabolic Disease.

Skin cancers, blindness, and anterior tongue mass in African brothers.

Sikandar G. Khan, K. Kraemer, D. Tamura, 2008, Journal of the American Academy of Dermatology.

Adult-onset xeroderma pigmentosum neurological disease--observations in an autopsy case.

S. Merchant, R. Brumback, K. Kraemer, 2002, Clinical neuropathology.

Xeroderma Pigmentosum: Spinal Cord Astrocytoma with 9-Year Survival after Radiation and Isotretinoin Therapy

N. Patronas, K. Kraemer, J. DiGiovanna, 1998, Journal of cutaneous medicine and surgery.

In-vivo assessment of DNA ligation efficiency and fidelity in cells from patients with Fanconi's anemia and other cancer-prone hereditary disorders.

C. Bauer, K. Kraemer, T. M. Rünger, 1993, Toxicology letters.

Hypermutability of UV-treated plasmids in dysplastic nevus/familial melanoma cell lines.

M. Tucker, A. Goldstein, R. Tarone, 1997, Cancer research.

Dysplastic nevus syndrome and cancer risk--response.

K. Kraemer, 1987, Journal of the American Academy of Dermatology.

Dysplastic nevi on the scalp of prepubertal children from melanoma-prone families.

W. Clark, D. Elder, M. Greene, 1983, The Journal of pediatrics.

Debilitating hip degeneration in trichothiodystrophy: Association with ERCC2/XPD mutations, osteosclerosis, osteopenia, coxa valga, contractures, and osteonecrosis

Sikandar G. Khan, S. Paul, K. Kraemer, 2022, American journal of medical genetics. Part A.

Trichothiodystrophy hair shafts display distinct ultrastructural features

Sikandar G. Khan, R. Rice, K. Kraemer, 2022, Experimental dermatology.

Management of Xeroderma Pigmentosum

K. Kraemer, D. Tamura, J. DiGiovanna, 2018, DNA Repair Disorders.

Mutations in the TTDN1 gene are associated with a distinct trichothiodystrophy phenotype

Sikandar G. Khan, K. Kraemer, D. Tamura, 2014, The Journal of investigative dermatology.

High‐risk pregnancy and neonatal complications in the DNA repair and transcription disorder trichothiodystrophy: report of 27 affected pregnancies

Sikandar G. Khan, M. Tucker, A. Goldstein, 2011, Prenatal diagnosis.

Brittle hair, developmental delay, neurologic abnormalities, and photosensitivity in a 4-year-old girl.

Sikandar G. Khan, N. Patronas, W. Zein, 2010, Journal of the American Academy of Dermatology.

The effect of donor age on the processing of UV-damaged DNA by cultured human cells: reduced DNA repair capacity and increased DNA mutability.

R. Tarone, L. Grossman, K. Kraemer, 1996, Mutation research.

Quantification of expression of linked cloned genes in a simian virus 40-transformed xeroderma pigmentosum cell line

D. Whyte, B. Howard, C. Gorman, 1985, Molecular and cellular biology.

Lessons Learned from Xeroderma Pigmentosum

K. Kraemer, 1996, Photochemistry and photobiology.

Forty Years of Research on Xeroderma Pigmentosum at the US National Institutes of Health

K. Kraemer, J. DiGiovanna, 2015, Photochemistry and photobiology.

An SV40-transformed xeroderma pigmentosum group D cell line: establishment, ultraviolet sensitivity, transfection efficiency and plasmid mutation induction.

M. Seidman, S. Seetharam, K. Kraemer, 1986, Mutation research.

Abnormal XPD-induced nuclear receptor transactivation in DNA repair disorders: trichothiodystrophy and xeroderma pigmentosum

Sikandar G. Khan, J. Egly, T. Ueda, 2012, European Journal of Human Genetics.

Ocular manifestations of trichothiodystrophy.

Sikandar G. Khan, J. Clayton, W. Zein, 2011, Ophthalmology.

Host cell reactivation by human cells of DNA expression vectors damaged by ultraviolet radiation or by acid-heat treatment.

K. Kraemer, M. Protić-Sabljić, 1986, Carcinogenesis.

Carrier detection in xeroderma pigmentosum.

R. Parshad, R. Tarone, K. Sanford, 1990, The Journal of clinical investigation.

Founder mutations in xeroderma pigmentosum.

K. Kraemer, D. Tamura, J. DiGiovanna, 2010, The Journal of investigative dermatology.

The Activation Of ATM Depends On Chromatin Interactions Occurring Prior To DNA-Damage Induction

G. Gerlitz, Y. Shiloh, A. Nussenzweig, 2008, Nature Cell Biology.

For the record: the history of precursors to malignant melanoma.

W. Clark, D. Elder, D. Guerry, 1984, Archives of dermatology.

N‐methyl‐N‐nitrosourea‐lnduced mutations in a shuttle plasmid replicated in human cells

L. C. Waters, M. Sikpi, R. J. Preston, 1990, Molecular carcinogenesis.

Inhibition of mixed leukocyte culture reaction by 8-methoxypsoralen and long-wavelength ultraviolet radiation.

R. Tarone, K. Kraemer, W. Levis, 1981, The Journal of investigative dermatology.

Strict sun protection results in minimal skin changes in a patient with xeroderma pigmentosum and a novel c.2009delG mutation in XPD (ERCC2)

Sikandar G. Khan, A. Bircher, T. Ueda, 2009, Experimental dermatology.

Xeroderma pigmentosum/cockayne syndrome complex: first neuropathological study and review of eight other cases.

D. Dickson, I. Rapin, K. Kraemer, 2001, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

Cornifying Darier disease--a unique variant. II. Surgical treatment.

K. Kraemer, G. Peck, K. Cohen, 1976, Archives of dermatology.

Differences in peripheral neuropathy in xeroderma pigmentosum complementation groups A and D as evaluated by nerve conduction studies

Sikandar G. Khan, N. Patronas, T. Lehky, 2021, BMC Neurology.

The DNA repair genes XPB and XPD defend cells from retroviral infection.

F. Bushman, A. Sarasin, R. Fishel, 2006, Proceedings of the National Academy of Sciences of the United States of America.

DNA repair disorders with overlaps and paradoxes

I. Rapin, K. Kraemer, J. Robbins, 2000 .

Reduced DNA repair in cultured melanocytes and nevus cells from a patient with xeroderma pigmentosum.

W. Clark, V. Hearing, S. Yuspa, 1989, Archives of dermatology.

Topical immunotherapy of basal cell carcinomas with dinitrochlorobenzene.

K. Kraemer, W. Klingler, G. Peck, 1973, Cancer research.

Normal vitamin D levels can be maintained despite rigorous photoprotection: six years' experience with xeroderma pigmentosum.

K. Kraemer, J. DiGiovanna, R B Sollitto, 1997, Journal of the American Academy of Dermatology.

Xeroderma Pigmentosum: An Inherited Disease with Sun Sensitivity, Multiple Cutaneous Neoplasms, and Abnormal DNA Repair

K. Kraemer, H. Coon, M. Lutzner, 1974 .

DNA crosslinking and cell survival in human lymphoid cells treated with 8-methoxypsoralen and long wavelength ultraviolet radiation.

K. Kohn, K. Kraemer, D. Glaubiger, 1981, Mutation research.

Trichothiodystrophy: a systematic review of 112 published cases characterises a wide spectrum of clinical manifestations

K. Kraemer, D. Tamura, J. DiGiovanna, 2008, Journal of Medical Genetics.

Decreased thymidine incorporation in circulating leukocytes after treatment of psoriasis with psoralen and long-wave ultraviolet light.

G. Weinstein, K. Kraemer, Kenneth H. Kraemer, 1977, The Journal of investigative dermatology.

Ataxia-Telangiectasia: A Multisystem Hereditary Disease with Immunodeficiency, Impaired Organ Maturation, X-Ray Hypersensitivity, and a High Incidence of Neoplasia

T. Waldmann, K. Kraemer, D. Nelson, 1983 .

DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum.

K. Kraemer, J. Scotto, M. M. Lee, 1984, Carcinogenesis.

Cornifying Darier disease--a unique variant. I. Report of a case.

K. Kraemer, W. Klingler, G. Peck, 1976, Archives of dermatology.

Ophthalmic manifestations and histopathology of xeroderma pigmentosum: two clinicopathological cases and a review of the literature.

K. Kraemer, D. Tamura, J. DiGiovanna, 2011, Survey of ophthalmology.

Clearing of melanoma in situ with intralesional interferon alfa in a patient with xeroderma pigmentosum.

M. Turner, M. Roth, K. Kraemer, 1994, Archives of dermatology.

Repair of DNA in xeroderma pigmentosum conjunctiva.

K. Kraemer, D. Newsome, J. Robbins, 1975, Archives of ophthalmology.

Retinoid protection against x-ray-induced chromatid damage in human peripheral blood lymphocytes.

R. Parshad, R. Tarone, F. Price, 1992, The Journal of clinical investigation.

High risk of malignant melanoma in melanoma-prone families with dysplastic nevi.

W. Clark, D. Elder, M. Greene, 1985, Annals of internal medicine.

Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair

Sikandar G. Khan, M. Tucker, A. Goldstein, 2010, Journal of Medical Genetics.

Joining of linear plasmid DNA is reduced and error‐prone in Bloom's syndrome cells.

K. Kraemer, T. M. Rünger, 1989, The EMBO journal.

Burning issues in the diagnosis of xeroderma pigmentosum

K. Kraemer, D. Tamura, S.G. Khan, 2013, The British journal of dermatology.

Defective DNA repair in humans: clinical and molecular studies of xeroderma pigmentosum.

R. Parshad, R. Tarone, D. Brash, 1990, Basic life sciences.

PSORALEN PLUS ULTRAVIOLET RADIATION‐INDUCED INHIBITION OF DNA SYNTHESIS AND VIABILITY IN HUMAN LYMPHOID CELLS IN VITRO*

R. Tarone, K. Kraemer, O. Ellingson, 1979, Photochemistry and photobiology.

Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas

Sikandar G. Khan, M. Raffeld, M. C. Hollander, 2009, Proceedings of the National Academy of Sciences.

The dysplastic nevus syndrome: our definition.

W. Clark, D. Elder, D. Guerry, 1982, The American Journal of dermatopathology.

Dysplastic nevi as precursors to hereditary melanoma.

K. Kraemer, 1983, The Journal of dermatologic surgery and oncology.

Abnormal rate and duration of ultraviolet-induced thymidine incorporation into lymphocytes from patients with Xeroderma pigmentosum and associated neurological complications.

K. Kraemer, J. Robbins, 1972, Mutation research.

Prolonged ultraviolet-induced thymidine incorporation into xeroderma pigmentosum lymphocytes: studies on its duration, amount, localization and relationship to hydroxyurea.

K. Kraemer, J. Robbins, 1972, Biochimica et biophysica acta.

Global contributions to the understanding of DNA repair and skin cancer.

K. Kraemer, J. DiGiovanna, 2014, The Journal of investigative dermatology.

DNA repair in tumor cells from the variant form of xeroderma pigmentosum.

B. Flaxman, K. Kraemer, J. Robbins, 1975, The Journal of investigative dermatology.

Influence of ataxia telangiectasia gene dosage on bleomycin-induced chromosome breakage and inhibition of replication in human lymphoblastoid cell lines.

K. Kraemer, P. Kohn, J. K. Buchanan, 1982, Experimental cell research.

Effect of X-radiation on DNA and histone synthesis in ataxia telangiectasia and normal lymphoblastoid cells.

M. Bustin, K. Kraemer, N. Soares, 1983, Mutation research.

A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism.

Sikandar G. Khan, E. Metter, S. Bale, 2000, Carcinogenesis.

Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene.

A. Lehmann, J. Krutmann, S. Queillé, 2001, Human molecular genetics.

Xeroderma pigmentosum and related disorders: examining the linkage between defective DNA repair and cancer.

M. Seidman, K. Kraemer, C. Parris, 1994, The Journal of investigative dermatology.

Xeroderma pigmentosum-variant patients from America, Europe, and Asia.

Roger Woodgate, Hiroki Inui, Wen Hao Wu, 2008, The Journal of investigative dermatology.

DNA polymerase η is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

P. Gearhart, A. Lehmann, Xianmin Zeng, 2001, Nature Immunology.

Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

Michael Bustin, Jae-Hwan Lim, M. Bustin, 2003, The EMBO journal.

SHINING A LIGHT ON XERODERMA PIGMENTOSUM

K. Kraemer, J. DiGiovanna, 2012, The Journal of investigative dermatology.

The Role of Polymerase η in Somatic Hypermutation Determined by Analysis of Mutations in a Patient with Xeroderma Pigmentosum Variant

P. Lipsky, K. Kraemer, Ş. Yavuz, 2002, The Journal of Immunology.

An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study.

Sikandar G. Khan, Hongbing Shen, M. Spitz, 2001, Cancer research.

Expression of a transfected DNA repair gene (XPA) in xeroderma pigmentosum group A cells restores normal DNA repair and mutagenesis of UV-treated plasmids.

K. Tanaka, K. Kraemer, M. Saijo, 1995, Carcinogenesis.

Hydroa vacciniforme-like lymphoproliferative disorder: an EBV disease with a low risk of systemic illness in Caucasians.

F. Collins, T. Myers, E. Jaffe, 2019, Blood.

Sequence specificity of aflatoxin B1-induced mutations in a plasmid replicated in xeroderma pigmentosum and DNA repair proficient human cells.

J. Groopman, M. Seidman, K. Kraemer, 1992, Cancer research.

XPC branch‐point sequence mutations disrupt U2 snRNP binding, resulting in abnormal pre‐mRNA splicing in xeroderma pigmentosum patients

Sikandar G. Khan, K. Yamanegi, Zhi-Ming Zheng, 2010, Human mutation.

Oculo-Cutaneous and Internal Neoplasms in Xeroderma Pigmentosum: Implications for Theories of Carcinogenesis

K. Kraemer, 1980 .

Four-dimensional, dynamic mosaicism is a hallmark of normal human skin that permits mapping of the organization and patterning of human epidermis during terminal differentiation

Sikandar G. Khan, K. Kraemer, D. Tamura, 2018, PloS one.

Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells.

M. Seidman, A. Bredberg, K. Kraemer, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Heterozygous individuals bearing a founder mutation in the XPA DNA repair gene comprise nearly 1% of the Japanese population.

C. Land, K. Kodama, K. Mabuchi, 2006, Mutation research.

EARLY ONSET OF SKIN AND ORAL CAVITY NEOPLASMS IN XERODERMA PIGMENTOSUM

K. Kraemer, J. Scotto, M. M. Lee, 1982, The Lancet.

Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia.

H L Levy, T D Schneider, Sikandar G. Khan, 1998, The Journal of investigative dermatology.

Survival of human lymphoblastoid cells after DNA damage measured by growth in microtiter wells.

K. Kraemer, H. Waters, J. K. Buchanan, 1980, Mutation research.

UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells.

E. Appella, M. Bustin, S. Mazur, 2011, DNA repair.

Age-associated changes in DNA repair and mutation rates

R. Tarone, Q. Wei, L. Grossman, 2001 .

Mutational hotspot variability in an ultraviolet-treated shuttle vector plasmid propagated in xeroderma pigmentosum and normal human lymphoblasts and fibroblasts.

M. Seidman, S. Seetharam, K. Kraemer, 1990, Journal of molecular biology.

Predisposition to hematologic malignancies in patients with xeroderma pigmentosum

Sikandar G. Khan, K. Oetjen, K. Calvo, 2020, Haematologica.

PIGMENTOSUM: IMPLICATIONS FOR THEORIES OF CARCINOGENESIS

K. Kraemer, 1980 .

Use of Human Lymphoblastoid Cell Lines to Determine Cellular Hypersensitivity to Physical and Chemical Agents

K. Kraemer, 1983 .

Repair Proficient Human Cells Plasmid Replicated in Xeroderma Pigmentosum and DNA-induced Mutations in a 1 Sequence Specificity of Aflatoxin B Updated

J. Groopman, M. Seidman, K. Kraemer, 2006 .

DNA Repair and Mutagenesis Induced by Dimer and Non-Dimer Photoproducts Measured with Plasmid Vectors in Xeroderma Pigmentosum Cells

D. Brash, M. Seidman, S. Seetharam, 1989 .

Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair

Y. Pommier, S. Akiyama, D. Zimonjic, 2001, Nature Medicine.

Xeroderma Pigmentosum: A Model for Human Premature Aging.

Sikandar G. Khan, K. Kraemer, D. Tamura, 2021, The Journal of investigative dermatology.

Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case-control study.

Sikandar G. Khan, C. Berking, I. König, 2005, Carcinogenesis.

No association between three xeroderma pigmentosum group C and one group G gene polymorphisms and risk of cutaneous melanoma

Sikandar G. Khan, I. König, A. Ziegler, 2005, European Journal of Human Genetics.

Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes.

M. Spitz, Q. Wei, L. Grossman, 2002, Mutation research.

A novel complex insertion/deletion mutation in the XPC DNA repair gene leads to skin cancer in an Iraqi family.

Sikandar G. Khan, J. Simon, K. Kraemer, 2006, The Journal of investigative dermatology.

GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy.

Sikandar G. Khan, R. Stephens, S. Seneca, 2016, American journal of human genetics.

Xeroderma pigmentosum complementation group G patient with a novel homozygous missense mutation and no neurological abnormalities

Sikandar G. Khan, K. Kraemer, S. Moriwaki, 2012, Experimental dermatology.

Site-specific oxidative DNA damage at polyguanosines produced by copper plus hydrogen peroxide.

J. Sagripanti, K. Kraemer, 1989, The Journal of biological chemistry.

Living with xeroderma pigmentosum: comprehensive photoprotection for highly photosensitive patients

Sikandar G. Khan, K. Kraemer, D. Tamura, 2014, Photodermatology, photoimmunology & photomedicine.

Characterization of tiger-tail banding and hair shaft abnormalities in trichothiodystrophy.

R. Schiffmann, K. Kraemer, J. DiGiovanna, 2004, Journal of the American Academy of Dermatology.

Ultraviolet Mutagenesis of a Shuttle Vector Plasmid in Repair Proficient and Deficient Human Cells

D. Brash, M. Seidman, A. Bredberg, 1991 .

Molecular Studies of Mutagenesis using Plasmid Vectors in Xeroderma Pigmentosum Cells

D. Brash, M. Seidman, S. Seetharam, 1989 .

The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D)

Sikandar G. Khan, H. Fine, N. Patronas, 2013, Acta Neuropathologica Communications.

Xeroderma Pigmentosum and Other DNA Repair-Deficient Photodermatoses

K. Kraemer, M. Berneburg, 2007 .

The human DNA repair gene, ERCC2 (XPD), corrects ultraviolet hypersensitivity and ultraviolet hypermutability of a shuttle vector replicated in xeroderma pigmentosum group D cells.

L. Prakash, M. Seidman, K. Kraemer, 1994, Cancer research.

Alterations in leukocyte aryl hydrocarbon hydroxylase activity associated with treatment and age in psoriasis patients and healthy individuals

R. Tarone, K. Kraemer, H. Gelboin, 2004, Archives of Dermatological Research.

Histopathology of the Inner Ear in Patients With Xeroderma Pigmentosum and Neurologic Degeneration

J. Nadol, C. Brewer, K. Kraemer, 2013, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

Auditory analysis of xeroderma pigmentosum 1971-2012: hearing function, sun sensitivity and DNA repair predict neurological degeneration.

Sikandar G. Khan, R. Schiffmann, S. Merchant, 2013, Brain : a journal of neurology.

Contact Allergy to Tylosin

G. Weinstein, K. Kraemer, V. Torres, 1976 .

Neurodegeneration as the presenting symptom in 2 adults with xeroderma pigmentosum complementation group F

Rena A. Godfrey, C. Toro, W. Gahl, 2018, Neurology: Genetics.

Relationship of DNA strand breakage produced by bromodeoxyuridine to topoisomerase II activity in Bloom-syndrome fibroblasts.

Y. Pommier, D. Kerrigan, K. Kraemer, 1991, Mutation research.

The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D)

Sikandar G. Khan, H. Fine, S. Hewitt, 2013, Acta neuropathologica communications.

Complementing xeroderma pigmentosum fibroblasts restore biological activity to UV-damaged DNA.

R. Day, K. Kraemer, J. Robbins, 1975, Mutation research.