J. Oshima

发表

ERCC4 variants identified in a cohort of patients with segmental progeroid syndromes

D. Nickerson, M. Bamshad, L. Hudgins, 2018, Human mutation.

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

G. Schellenberg, E. Wijsman, D. Galas, 1995, Science.

WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations

M. Poot, H. Hoehn, D. Lessel, 2010, Human Genetics.

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.

Junko Oshima, G. Hunninghake, M. Monick, 2009, American journal of respiratory and critical care medicine.

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

Peter Nürnberg, Ivan Dikic, Melanie Bahlo, 2014, Nature Genetics.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Mismatch repair in extracts of Werner syndrome cell lines.

T. Kunkel, R. Monnat, A. Umar, 1997, Cancer research.

Werner Syndrome Protein

M. Gray, L. Loeb, J. Oshima, 1998, The Journal of Biological Chemistry.

A Novel LMNA Mutation Causes Altered Nuclear Morphology and Symptoms of Familial Partial Lipodystrophy (Dunnigan Variety) with Progeroid Features

D. Lessel, F. Hisama, C. Kubisch, 2010, Molecular Syndromology.

Genomic structure and expression of STM2, the chromosome 1 familial Alzheimer disease gene.

G. Schellenberg, Y. Fu, P. Poorkaj, 1996, Genomics.

An encouraging progress report on the treatment of progeria and its implications for atherogenesis.

F. Hisama, G. Martin, J. Oshima, 2014, Circulation.

Coronary artery disease in a Werner syndrome‐like form of progeria characterized by low levels of progerin, a splice variant of lamin A

K. McBride, D. Lessel, F. Hisama, 2011, American journal of medical genetics. Part A.

LMNA mutations in atypical Werner's syndrome

I. Mian, B. Kennedy, N. B. Hanson, 2003, The Lancet.

Homozygosity mapping of the Werner syndrome locus (WRN).

J. Weber, G. Schellenberg, E. Wijsman, 1994, Genomics.

CTC1 mutations in a Brazilian family with progeroid features and recurrent bone fractures

D. Sillence, M. Dorschner, D. Lessel, 2018, Molecular genetics & genomic medicine.

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

K. E. Hunt, M. Poot, P. Rabinovitch, 1997, Human Genetics.

Targeted long-read sequencing identifies missing pathogenic variants in unsolved Werner syndrome cases

E. Eichler, F. Hisama, K. Yokote, 2022, Journal of Medical Genetics.

SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome—the Myhre syndrome

F. Hisama, Takayasu Mori, G. Martin, 2021, GeroScience.

Phenomics and lamins: from disease to therapy.

R. Hegele, J. Oshima, 2007, Experimental cell research.

Search and Insights into Novel Genetic Alterations Leading to Classical and Atypical Werner Syndrome

F. Hisama, J. Oshima, 2014, Gerontology.

Association between APOE ε 2/ ε 3/ ε 4 polymorphism and disability severity in a national long-term care survey sample

K. Manton, G. Martin, A. Kulminski, 2008 .

Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes

M. Poot, T. Haaf, T. Müller, 2019, Aging cell.

Fundamentals of cell proliferation: control of the cell cycle.

J. Campisi, J. Oshima, Judith Campisi, 1991, Journal of dairy science.

Oxidative Stress Induced Senescence Gives Rise to Transcriptionally Distinct Physiological States

J. Oshima, Nikolay Burnaevskiy, A. Mendenhall, 2022, bioRxiv.

The G 2-phase Decatenation Checkpoint Is Defective in Werner Syndrome Cells 1 , 2

J. Oshima, A. Franchitto, P. Pichierri, 2003 .

The G2-phase decatenation checkpoint is defective in Werner syndrome cells.

J. Oshima, A. Franchitto, P. Pichierri, 2003, Cancer research.

The Werner syndrome protein: an update

J. Oshima, 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.

S. Edland, S. Deeb, R. Tilvis, 2000, American journal of medical genetics.

Genetic diversity is a predictor of mortality in humans

Luigi Ferrucci, Alexander Teumer, Vilmundur Gudnason, 2014, BMC Genetics.

Gene action at the werner helicase locus: its role in the pathobiology of aging

M. Poot, P. Rabinovitch, M. Gray, 2001 .

The Werner syndrome protein is a DNA helicase

M. Gray, L. Loeb, G. Martin, 1997, Nature Genetics.

Uncommon cause of cirrhosis—A case of Werner syndrome with a novel WRN mutation

J. Oshima, S. Amalnath, D. Baskar, 2017, Indian Journal of Gastroenterology.

Functional deficit associated with a missense Werner syndrome mutation.

V. Bohr, Takashi Tadokoro, J. Oshima, 2013, DNA repair.

Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.

R. Schiestl, J. Oshima, R. Reliene, 2008, Mutation research.

WRN or telomerase constructs reverse 4-nitroquinoline 1-oxide sensitivity in transformed Werner syndrome fibroblasts.

S. Weissman, M. Meyn, F. Hisama, 2000, Cancer research.

Advances in Brief WRN or Telomerase Constructs Reverse 4-Nitroquinoline 1-Oxide Sensitivity in Transformed Werner Syndrome Fibroblasts 1

S. Weissman, M. Meyn, F. Hisama, 2000 .

WRN mutations in Werner syndrome

R. Monnat, M. Moser, J. Oshima, 1999, Human mutation.

Regional genomic instability predisposes to complex dystrophin gene rearrangements

L. D. White, A. Breman, C. Eng, 2009, Human Genetics.

TNF‐α/IFN‐γ synergy amplifies senescence‐associated inflammation and SARS‐CoV‐2 receptor expression via hyper‐activated JAK/STAT1

J. Oshima, J. Kirkland, T. Tchkonia, 2022, Aging cell.

Rapamycin decreases DNA damage accumulation and enhances cell growth of WRN-deficient human fibroblasts

G. Martin, J. Oshima, B. Saha, 2014, Aging cell.

Precision Medicine and Progress in the Treatment of Hutchinson-Gilford Progeria Syndrome.

F. Hisama, J. Oshima, 2018, JAMA.

LMNA mutations in progeroid syndromes.

B. Kennedy, J. Oshima, Shurong Huang, 2005, Novartis Foundation symposium.

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

Alex P. Reiner, Luigi Ferrucci, Steve Horvath, 2018, Aging.

POLD1 Germline Mutations in Patients Initially Diagnosed with Werner Syndrome

J. Baldwin, W. Brown, J. Högel, 2015, Human mutation.

Functional evidence for a metastasis suppressor gene for rat prostate cancer within a 60-kilobase region on human chromosome 8p21-p12.

J. Barrett, V. Larionov, G. Martin, 2002, Cancer research.

Advances in Brief Functional Evidence for a Metastasis Suppressor Gene for Rat Prostate Cancer within a 60-Kilobase Region on Human Chromosome 8 p 21p 121

J. Barrett, V. Larionov, G. Martin, 2002 .

LCR-initiated rearrangements at the IDS locus, completed with Alu-mediated recombination or non-homologous end joining

A. Breman, P. Ward, C. Eng, 2011, Journal of Human Genetics.

DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations

R. Risques, G. Martin, J. Oshima, 2013, Front. Genet..

Phenotypic heterogeneity in body fat distribution in patients with atypical Werner's syndrome due to heterozygous Arg133Leu lamin A/C mutation.

A. Garg, J. Oshima, Katherine N Jacob, 2005, The Journal of clinical endocrinology and metabolism.

Evidence against DNA polymerase β as a candidate gene for Werner syndrome

G. Schellenberg, C. Disteche, T. Ogihara, 1994, Human Genetics.

Ageing: Dietary protection for genes

G. Martin, J. Oshima, 2016, Nature.

High incidence of BSCL2 intragenic recombinational mutation in Peruvian type 2 Berardinelli–Seip syndrome

F. Hisama, Takayasu Mori, G. Martin, 2017, American journal of medical genetics. Part A.

Inactivating Mutations in Exonuclease and Polymerase Domains in DNA Polymerase Delta Alter Sensitivities to Inhibitors of dNTP Synthesis.

G. Martin, J. Oshima, A. Herr, 2019, DNA and cell biology.

Effect of Ku86 and DNA-PKcs deficiency on non-homologous end-joining and homologous recombination using a transient transfection assay.

R. Schiestl, M. B. Secretan, A. Bishop, 2004, Mutation research.

WRN's tenth anniversary.

V. Bohr, F. Hisama, J. Oshima, 2006, Science of aging knowledge environment : SAGE KE.

Atypical progeroid syndrome: An unknown helicase gene defect?

J. Oshima, C. Aalfs, A. Nieuwint, 2003, American journal of medical genetics. Part A.

Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation.

K. E. Hunt, G. Martin, J. Oshima, 1998, Nucleic acids research.

Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers.

E M Wijsman, G. Schellenberg, E. Wijsman, 1996, American journal of human genetics.

Positional Cloning of the Werner's Syndrome Gene

G. Schellenberg, E. Wijsman, Chang-En Yu, 1996, Science.

Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A.

P. Rabinovitch, R. Risques, G. Martin, 2008, Experimental cell research.

Lessons from human progeroid syndromes

George M. Martin, Junko Oshima, G. Martin, 2000, Nature.

Correction of cellular phenotypes of Hutchinson-Gilford Progeria cells by RNA interference

Joel H. Janes, Nataliya Libina, J. Campisi, 2005, Human Genetics.

How Research on Human Progeroid and Antigeroid Syndromes Can Contribute to the Longevity Dividend Initiative.

F. Hisama, G. Martin, J. Oshima, 2016, Cold Spring Harbor perspectives in medicine.

Chapter 18 – The Biological Basis of Aging: Implications for Medical Genetics

F. Hisama, G. Martin, J. Oshima, 2013 .

The genetics of human longevity.

A. Reiner, S. Cummings, E. Ziv, 2004, The American journal of medicine.

Analysis of microsatellite instability and hypermutation of immunoglobulin variable genes in Werner syndrome

V. Bohr, P. Gearhart, J. Oshima, 2001, Mechanisms of Ageing and Development.

Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains.

W. Funk, J. Oshima, W D Funk, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Werner helicase expression in human fetal and adult aortas

H. Youssoufian, G. Martin, J. Oshima, 1999, Experimental Gerontology.

WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair

Junko Oshima, Judith Campisi, R. Schiestl, 2003, Aging cell.

Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.

G. Schellenberg, E. Wijsman, J. Nakura, 1997, American journal of human genetics.

Accumulation of Werner protein at DNA double-strand breaks in human cells

S. Nakajima, A. Yasui, A. Nussenzweig, 2005, Journal of Cell Science.

The Werner syndrome protein is involved in RNA polymerase II transcription.

M. Gray, V. Bohr, A. Balajee, 1999, Molecular biology of the cell.

Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence

J. Oshima, Nikolay Burnaevskiy, A. Mendenhall, 2022, GeroScience.

Werner syndrome protein limits MYC-induced cellular senescence.

B. Clurman, D. Russell, R. Monnat, 2003, Genes & development.

Atypical Aicardi‐Goutieres syndrome: Is the WRN locus a modifier?

D. Lessel, P. Nürnberg, F. Hisama, 2014, American journal of medical genetics. Part A.

Characterization of the human and mouse WRN 3'-->5' exonuclease.

N. Ellis, J. Campisi, J. Oshima, 2000, Nucleic acids research.

Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions

R. Monnat, J. Oshima, J. Sidorova, 2017, Ageing Research Reviews.

Werner protein recruits DNA polymerase delta to the nucleolus.

S. Weissman, A. Szekely, J. Oshima, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease

I. Saira Mian, Junko Oshima, Judith Campisi, 1998, Nature Genetics.

What Geriatricians Should Know About the Werner Syndrome

M. Poot, M. Gray, G. Martin, 1999, Journal of the American Geriatrics Society.

RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting

K. Yokote, J. Oshima, Y. Maezawa, 2018, Mechanisms of Ageing and Development.

Leukocyte Telomere Length Is Associated with Disability in Older U.S. Population

A. Yashin, P. Rabinovitch, R. Risques, 2010, Journal of the American Geriatrics Society.

The spectrum of WRN mutations in Werner syndrome patients

Markus Schuelke, Thomas Dorn, Johannes Ring, 2006, Human mutation.

WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects

M. Poot, A. Federico, D. Schindler, 2017, Human mutation.

The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.

C. Harris, R. Beyer, R. Monnat, 2016, Human molecular genetics.

Accelerated epigenetic aging in Werner syndrome

S. Horvath, T. Haaf, G. Martin, 2017, Aging.

DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome

S. Horvath, A. Mégarbané, T. Haaf, 2022, Aging cell.

Review of How Genetic Research on Segmental Progeroid Syndromes Has Documented Genomic Instability as a Hallmark of Aging But Let Us Now Pursue Antigeroid Syndromes!

F. Hisama, G. Martin, J. Oshima, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

Dysfunction of the MDM2/p53 axis is linked to premature aging.

C. Prives, J. Högel, David R. Tong, 2017, The Journal of clinical investigation.

Ethnic-specific WRN mutations in South Asian Werner syndrome patients: potential founder effect in patients with Indian or Pakistani ancestry

D. Lessel, S. Nampoothiri, G. Nürnberg, 2013, Molecular genetics & genomic medicine.

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis

V. Bohr, J. Oshima, W. Cheng, 2008, Human Genetics.

Werner Syndrome

J. Oshima, Li-shan Chen, Dongyou Liu, 2020, Constitutional Oncogenetics.

Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population.

T. Ogihara, S. Edland, J. Higaki, 1997, American journal of medical genetics.

Werner helicase is localized to transcriptionally active nucleoli of cycling cells.

M. Gray, H. Youssoufian, G. Martin, 1998, Experimental cell research.

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A.

M. Gray, L. Loeb, J. Oshima, 1998, Nucleic acids research.

Multisystem Progeroid Syndrome With Lipodystrophy, Cardiomyopathy, and Nephropathy Due to an LMNA p.R349W Variant

R. Hegele, A. Garg, M. Linton, 2020, Journal of the Endocrine Society.

Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains

W. Funk, J. Oshima, P. Whittier, 2001 .

Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy

J. Bell, A. Mégarbané, G. Martin, 2023, Human molecular genetics.

Homozygous and compound heterozygous mutations at the Werner syndrome locus.

G. Schellenberg, T. Ogihara, J. Nakura, 1996, Human molecular genetics.

Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene.

C. Ware, H. Youssoufian, G. Martin, 2000, Genetics.

SOD2 polymorphisms: unmasking the effect of polymorphism on splicing

K. Manton, Hai Huang, Lin Lee, 2007, BMC Medical Genetics.

Werner syndrome helicase modulates G4 DNA-dependent transcription and opposes mechanistically distinct senescence-associated gene expression programs

C. Harris, R. Beyer, R. Monnat, 2015, bioRxiv.

Werner protein recruits DNA polymerase δ to the nucleolus

S. Weissman, A. Szekely, J. Oshima, 2000 .

Alterations of chaperone protein expression in presenilin mutant neurons in response to glutamate excitotoxicity

Q. Hu, G. Martin, J. Oshima, 2002, Pathology international.

Truncated prelamin A expression in HGPS-like patients: a transcriptional study

R. Wevers, N. Lévy, E. Morava, 2015, European Journal of Human Genetics.

Linkage disequilibrium and haplotype studies of chromosome 8p 11.1-21.1 markers and Werner syndrome.

G. Schellenberg, E. Wijsman, T. Ogihara, 1994, American journal of human genetics.

Polymorphisms at the Werner locus: I. Newly identified polymorphisms, ethnic variability of 1367Cys/Arg, and its stability in a population of Finnish centenarians.

K. E. Hunt, S. Edland, S. Deeb, 1999, American journal of medical genetics.

Integrated mapping analysis of the Werner syndrome region of chromosome 8.

J. Weber, C. Disteche, M. Boehnke, 1994, Genomics.

Novel LMNA mutations in Greek and Myanmar Patients with Progeroid Features and Cardiac Manifestations

F. Hisama, G. Martin, J. Oshima, 2020, Aging pathobiology and therapeutics.

Lack of WRN results in extensive deletion at nonhomologous joining ends.

R. Schiestl, J. Campisi, J. Oshima, 2002, Cancer research.

Modulation of cell growth, p34cdc2 and cyclin A levels by SV-40 large T antigen.

J. Campisi, R. Schlegel, J. Oshima, 1993, Oncogene.

Regulation of c‐fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors

J. Campisi, G. Martin, J. Oshima, 1995, Journal of cellular physiology.

I. DNA HELICASE AND DNA EXONUCLEASE RESIDE ON THE SAME POLYPEPTIDE

M. Gray, L. Loeb, J. Oshima, 1998 .

Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes.

M. Emond, R. Monnat, M. Moser, 2000, Cancer research.

Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene.

J. Campisi, J. Oshima, T. Seshadri, 1993, The Journal of biological chemistry.

Werner syndrome through the lens of tissue and tumour genomics

Scott R. Kennedy, P. Welcsh, R. Monnat, 2016, Scientific Reports.

Association between APOE epsilon 2/epsilon 3/epsilon 4 polymorphism and disability severity in a national long-term care survey sample.

A. Yashin, K. Manton, A. Kulminski, 2008, Age and ageing.

Renal dysfunction, malignant neoplasms, atherosclerotic cardiovascular diseases, and sarcopenia as key outcomes observed in a three-year follow-up study using the Werner Syndrome Registry

M. Kuzuya, K. Yokote, H. Nakagami, 2023, Aging.

Transfection of Neuroprogenitor Cells with Iron Nanoparticles for Magnetic Resonance Imaging Tracking: Cell Viability, Differentiation, and Intracellular Localization

Yongmin Kim, S. Minoshima, D. Cross, 2005, Molecular Imaging and Biology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

WRN helicase expression in Werner syndrome cell lines.

R. Monnat, M. Moser, J. Oshima, 2000, Nucleic acids research.

Recent Advances in Understanding Werner Syndrome [version 1; peer review: 3 approved]

V. Bohr, K. Yokote, J. Oshima, 2022 .

Cell-to-Cell Variation in Gene Expression for Cultured Human Cells is Controlled in Trans by Diverse Genes: Implications for the Pathobiology of Aging.

W. Han, P. Ladd, Lin Lee, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

A YAC, P1, and cosmid contig and 17 new polymorphic markers for the Werner syndrome region at 8p12-p21.

B. Trask, G. Schellenberg, F. Hisama, 1996, Genomics.

Werner syndrome in a Lebanese family

D. Lessel, M. Nasrallah, J. Oshima, 2022, American journal of medical genetics. Part A.

A Case Report of Werner’s Syndrome With a Novel Mutation From India

J. Oshima, Namrata Chhabra, Satyaki Ganguly, 2020, Cureus.

Characteristic Clinical Features of Werner Syndrome with a Novel Compound Heterozygous WRN Mutation c.1720+1G>A Plus c.3139-1G>C

K. Abe, K. Yokote, M. Takemoto, 2018, Internal medicine.

Biallelic WRN Mutations in Newly Identified Japanese Werner Syndrome Patients

T. Kusaka, M. Kuzuya, K. Yokote, 2018, Molecular Syndromology.

Clinical utility gene card for: Werner Syndrome - Update 2014

F. Hisama, C. Kubisch, G. Martin, 2014, European Journal of Human Genetics.

Clinical utility gene card for: Werner syndrome

F. Hisama, C. Kubisch, G. Martin, 2012, European Journal of Human Genetics.

Collagen expression in fibroblasts with a novel LMNA mutation.

G. Martin, J. Oshima, D. Leistritz, 2007, Biochemical and biophysical research communications.

No detectable mutations at Werner helicase locus in progeria

W. Brown, G. Martin, J. Oshima, 1996, The Lancet.

Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex

S. Schwartz, J. Alijotas-Reig, J. Oshima, 2023, Aging.

A Flanking Gene Problem Leads to the Discovery of a Gprc5b Splice Variant Predominantly Expressed in C57Bl/6J Mouse Brain and in Maturing Neurons

Q. Hu, Lin Lee, G. Martin, 2010, PLoS ONE.

Health‐Protective and Adverse Effects of the Apolipoprotein E ɛ2 Allele in Older Men

A. Yashin, K. Manton, A. Kulminski, 2008, Journal of the American Geriatrics Society.

Werner Syndrome

J. Oshima, Li-shan Chen, 2002, Journal of biomedicine & biotechnology.

Werner Syndrome

F. Hisama, J. Oshima, George M. Martin, 2019 .

Narrowing the position of the Werner syndrome locus by homozygosity analysis-extension of homozygosity analysis.

G. Schellenberg, E. Wijsman, T. Ogihara, 1996, Genomics.

LMNA mutations in atypical Werner's syndrome

C. Vigouroux, A. Garg, J. Capeau, 2003, The Lancet.

Aβ 1–40 enhances the proliferation of human diploid fibroblasts

G. Martin, J. Oshima, G. Zitnik, 2016, Neurobiology of Aging.

The Werner syndrome protein: an update

J. Oshima, 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.

G. Hunninghake, M. Monick, T. Nyunoya, 2009, American journal of respiratory and critical care medicine.

SOD2 polymorphisms: unmasking the effect of polymorphism on splicing

K. Manton, Hai Huang, Lin Lee, 2007, BMC Medical Genetics.

LMNA mutations in atypical Werner's syndrome

B. Kennedy, A. Garg, G. Martin, 2003, The Lancet.

An encouraging progress report on the treatment of progeria and its implications for atherogenesis.

F. Hisama, G. Martin, J. Oshima, 2014, Circulation.

An Encouraging Progress Report on the Treatment of Progeria and Its Implications for Atherogenesis Running Title: Oshima Et Al.; Progeria Clinical Trial

F. Hisama, J. Oshima, George M. Martin, 2022 .