John H. Wilson

发表

Transcription destabilizes triplet repeats

Yunfu Lin, L. Hubert, John H. Wilson, 2009, Molecular carcinogenesis.

Neural reprogramming in retinal degeneration.

Krista I Kinard, James R. Anderson, B. Jones, 2007, Investigative ophthalmology & visual science.

Molecular Biology of The Cell: A Problems Approach

Tim Hunt, T. Hunt, John H. Wilson, 2002 .

Molecular Biology of Eucaryotic Cells

William B. Wood, Leroy E. Hood, W. Wood, 1976 .

Pointing fingers at the limiting step in gene targeting

John H. Wilson, 2003, Nature Biotechnology.

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

S. Haggarty, S. Erdin, M. Talkowski, 2020, eLife.

GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells

D. Mittelman, John H. Wilson, B. Santillan, 2014, PloS one.

Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1.

Yunfu Lin, L. Hubert, John H. Wilson, 2011, Human molecular genetics.

Rhodopsin Gene Expression Determines Rod Outer Segment Size and Rod Cell Resistance to a Dominant-Negative Neurodegeneration Mutant

T. Wensel, John H. Wilson, I. Sandoval, 2012, PloS one.

Targeting vector configuration and method of gene transfer influence targeted correction of theAPRT gene in Chinese hamster ovary cells

John H. Wilson, R. Nairn, G. Adair, 1993, Somatic cell and molecular genetics.

Gene targeting in normal and amplified cell lines

John H. Wilson, Huiqing Zheng, 1990, Nature.

Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay.

T. Wensel, John H. Wilson, Ramon Roman-Sanchez, 2016, Experimental eye research.

Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy

A. Bradley, T. Wensel, John H. Wilson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Repair of chromosomal double-strand breaks by precise ligation in human cells.

Yunfu Lin, John H. Wilson, William Y. Lin, 2013, DNA repair.

Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa.

S. Wu, T. Wensel, John H. Wilson, 2011, Investigative ophthalmology & visual science.

Transcription promotes contraction of CAG repeat tracts in human cells

Yunfu Lin, John H. Wilson, Vincent Dion, 2006, Nature Structural &Molecular Biology.

Knockout punches with a fistful of zinc fingers

John H. Wilson, 2008, Proceedings of the National Academy of Sciences.

Mechanisms ofNonhomologous Recombination inMammalian Cells

John H. Wilson, T. Porter, 1985 .

Soy Protein Nanoﬁber Scaffolds for Uniform Maturation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium

A. Swaroop, Tiansen Li, P. Lelkes, 2020 .

The fractured genome of HeLa cells

D. Mittelman, John H. Wilson, 2013, Genome Biology.

Repair of single-stranded loops in I into mammalian cells

U. Weiss, John H. Wilson, M. Mclean, 2016 .

Distinct requirements for Ku in N nucleotide addition at V(D)J- and non-V(D)J-generated double-strand breaks.

D. Roth, John H. Wilson, M. Calicchio, 2004, Nucleic acids research.

BRCA2 Enters the Fray

S. Elledge, John H. Wilson, 2002, Science.

Convergent transcription through microsatellite repeat tracts induces cell death

Yunfu Lin, John H. Wilson, William Y. Lin, 2014, Molecular Biology Reports.

Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye.

T. Wensel, John H. Wilson, P. Carvounis, 2010, Investigative ophthalmology & visual science.

Manipulating the mammalian genome by homologous recombination

K. Vasquez, John H. Wilson, Z Intody, 2001, Proceedings of the National Academy of Sciences of the United States of America.

R loops stimulate genetic instability of CTG·CAG repeats

R. Wells, M. Napierala, S. Dent, 2009, Proceedings of the National Academy of Sciences.

Outer Segment Formation of Transplanted Photoreceptor Precursor Cells

T. Kurth, D. Corbeil, John H. Wilson, 2012, PloS one.

Activation of gene expression by triplex-directed psoralen crosslinks.

Jie Song, John H. Wilson, Mei Li, 2004, Gene.

Environmental Stress Induces Trinucleotide Repeat Mutagenesis in Human Cells by Alt-Nonhomologous End Joining Repair.

Yunfu Lin, John H. Wilson, Nimrat Chatterjee, 2016, Journal of molecular biology.

Insertion of a Telomere Repeat Sequence into a Mammalian Gene Causes Chromosome Instability

A. E. Kilburn, John H. Wilson, M. J. Shea, 2001, Molecular and Cellular Biology.

Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice

W. Hauswirth, T. Wensel, John H. Wilson, 2011, Nucleic acids research.

Microsatellite Repeats: Canaries in the Coalmine

John H. Wilson, Nimrat Chatterjee, B. Santillan, 2013 .

Effects of nicks on repair of single-stranded loops in heteroduplex DNA in mammalian cells

U. Weiss, J. H. Wilson, John H. Wilson, 1989, Somatic cell and molecular genetics.

Role of ERCC1 in removal of long non‐homologous tails during targeted homologous recombination

John H. Wilson, R. Nairn, G. Adair, 2000, The EMBO journal.

Targeted Recombination at the Chinese Hamster APRT Locus Using Insertion versus Replacement Vectors

J. H. Wilson, J. Scheerer, John H. Wilson, 1998, Somatic cell and molecular genetics.

Transcription-Induced CAG Repeat Contraction in Human Cells Is Mediated in Part by Transcription-Coupled Nucleotide Excision Repair

Yunfu Lin, John H. Wilson, 2007, Molecular and Cellular Biology.

Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells

D. Mittelman, Yunfu Lin, John H. Wilson, 2009, Proceedings of the National Academy of Sciences.

Instability and chromatin structure of expanded trinucleotide repeats.

John H. Wilson, Vincent Dion, 2009, Trends in genetics : TIG.

Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline.

R. Waterland, Yunfu Lin, L. Hubert, 2008, Human molecular genetics.

Defined oligomeric SV40 DNA: A sensitive probe of general recombination in somatic cells

John H. Wilson, C. Wake, 1980, Cell.

Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR.

Yunfu Lin, John H. Wilson, Nimrat Chatterjee, 2016, DNA repair.

Fanconi anemia pathway regulates convergent transcription-induced cell death at trinucleotide repeats in human cells.

Yunfu Lin, John H. Wilson, Nimrat Chatterjee, 2016, Postdoc journal : a journal of postdoctoral research and postdoctoral affairs.

Engineered Nucleases and Trinucleotide Repeat Diseases

D. Mittelman, John H. Wilson, Christopher Moye, 2016 .

Environmental stress induces trinucleotide repeat mutagenesis in human cells

Yunfu Lin, John H. Wilson, Nimrat Chatterjee, 2015, Proceedings of the National Academy of Sciences.

Transcription-induced DNA toxicity at trinucleotide repeats

Yunfu Lin, John H. Wilson, 2011, Cell cycle.

DNA end joining becomes less efficient and more error-prone during cellular senescence.

D. Mittelman, O. Pereira-smith, A. Seluanov, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Convergent Transcription through a Long CAG Tract Destabilizes Repeats and Induces Apoptosis

Yunfu Lin, John H. Wilson, Ma Wan, 2010, Molecular and Cellular Biology.

Hsp90 modulates CAG repeat instability in human cells

D. Mittelman, Yunfu Lin, John H. Wilson, 2010, Cell Stress and Chaperones.

Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.

Yunfu Lin, John H. Wilson, Yunfu Lin, 2009, DNA repair.

Convergent transcription through microsatellite repeat tracts induces cell death

Yunfu Lin, John H. Wilson, William Y. Lin, 2014, Molecular Biology Reports.

Stress, genomes, and evolution

D. Mittelman, John H. Wilson, 2010, Cell Stress and Chaperones.

Transcription and triplet repeat instability

Yunfu Lin, John H. Wilson, Vincent Dion, 2006 .

Nucleotide Excision Repair, Mismatch Repair, and R-Loops Modulate Convergent Transcription-Induced Cell Death and Repeat Instability

Yunfu Lin, John H. Wilson, 2012, PloS one.

Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination.

A. Seluanov, V. Gorbunova, Yunfu Lin, 2008, DNA repair.

Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells.

D. Mittelman, A. Seluanov, V. Gorbunova, 2004, Human molecular genetics.

Abrupt Onset of Mutations in a Developmentally Regulated Gene during Terminal Differentiation of Post-Mitotic Photoreceptor Neurons in Mice

T. Wensel, John H. Wilson, A. K. Gross, 2014, PloS one.

Rhodopsin–EGFP knock-ins for imaging quantal gene alterations

T. Wensel, John H. Wilson, A. K. Gross, 2005, Vision Research.

A novel selectable system for detecting expansion of CAG.CTG repeats in mammalian cells.

Yunfu Lin, John H. Wilson, Vincent Dion, 2005, Mutation research.

Selectable System for Monitoring the Instability of CTG/CAG Triplet Repeats in Mammalian Cells

A. Seluanov, V. Gorbunova, John H. Wilson, 2003, Molecular and Cellular Biology.

Long CTG Tracts from the Myotonic Dystrophy Gene Induce Deletions and Rearrangements during Recombination at the APRT Locus in CHO Cells

R. Wells, John H. Wilson, G. McKenzie, 2003, Molecular and Cellular Biology.

Topoisomerase 1 and Single-Strand Break Repair Modulate Transcription-Induced CAG Repeat Contraction in Human Cells

Yunfu Lin, L. Hubert, John H. Wilson, 2011, Molecular and Cellular Biology.

The nature of dominant mutations of rhodopsin and implications for gene therapy

T. Wensel, John H. Wilson, 2003, Molecular Neurobiology.

Efficient modification of the APRT gene by FLP/FRT site-specific targeting

R. V. Merrihew, John H. Wilson, R. G. Sargent, 1995, Somatic cell and molecular genetics.

Impaired photoreceptor protein transport and synaptic transmission in a mouse model of Bardet–Biedl syndrome

J. Lupski, S. Wu, N. Katsanis, 2007, Vision Research.

A common microRNA signature in mouse models of retinal degeneration.

K. Hokamp, Tiansen Li, John H. Wilson, 2008, Experimental eye research.

Cancer. BRCA2 enters the fray.

S. Elledge, John H. Wilson, 2002, Science.

Loss of photoreceptor potential from retinal progenitor cell cultures, despite improvements in survival.

C. Gallagher, F. Mansergh, John H. Wilson, 2010, Experimental eye research.

Role of the nucleotide excision repair gene ERCC1 in formation of recombination-dependent rearrangements in mammalian cells.

A. E. Kilburn, J. H. Wilson, John H. Wilson, 2000, Nucleic acids research.

Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases.

M. Brenneman, J. H. Wilson, John H. Wilson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Subcellular localization of mutant P23H rhodopsin in an RFP fusion knock-in mouse model of retinitis pigmentosa

T. Wensel, John H. Wilson, Michael A. Robichaux, 2021, bioRxiv.

Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration

T. Wensel, John H. Wilson, A. K. Gross, 2006, Vision Research.