D. Scicchitano

发表

Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.

L. Samson, B. Engelward, B. Plosky, 2002, DNA repair.

Transcription past DNA adducts derived from polycyclic aromatic hydrocarbons.

D. Scicchitano, 2005, Mutation research.

Transcription and DNA damage: a link to a kink.

I. Mellon, D. Scicchitano, Isabel Mellon, 1997, Environmental health perspectives.

Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription

C. Berens, A. Gandolfi, N. Geacintov, 2015, The Journal of Biological Chemistry.

Construction and puriﬁcation of site-speciﬁcally modiﬁed DNA templates for transcription assays

N. Geacintov, D. Scicchitano, R. Perlow, 2022 .

Intragenomic Repair Heterogeneity of DNA

P. Hanawalt, D. Scicchitano, 2016 .

Intragenomic repair heterogeneity of DNA damage.

P. Hanawalt, D. Scicchitano, 1992, Environmental health perspectives.

Lack of sequence-specific removal of N-methylpurines from cellular DNA.

P. Hanawalt, D. Scicchitano, 1990, Mutation research.

Measurements of genomic and gene-specific DNA repair of alkylation damage in cultured human T-lymphocytes.

S. Robison, D. Scicchitano, J. Hartshorn, 1990, Basic life sciences.

Relationships Between DNA Repair and Transcription in Defined DNA Sequences in Mammalian Cells

P. Hanawalt, G. Spivak, I. Mellon, 1989 .

Two expressed human genes sustain slightly more DNA damage after alkylating agent treatment than an inactive gene.

S. Robison, D. Scicchitano, J. D. Bartlett, 1991, Mutation research.

Site-specific benzo[a]pyrene diol epoxide-DNA adducts inhibit transcription elongation by bacteriophage T7 RNA polymerase.

N. Geacintov, D. Scicchitano, D. J. Choi, 1994, Biochemistry.

Functional nucleotide excision repair is required for the preferential removal of N-ethylpurines from the transcribed strand of the dihydrofolate reductase gene of Chinese hamster ovary cells

G. Plitas, D. Scicchitano, A. Sitaram, 1997, Molecular and cellular biology.

Incorrect base insertion and prematurely terminated transcripts during T7 RNA polymerase transcription elongation past benzo[a]pyrenediol epoxide-modified DNA.

N. Geacintov, D. Scicchitano, R. Roth, 1996, Journal of molecular biology.

3-Methyladenine and 7-methylguanine exhibit no preferential removal from the transcribed strand of the dihydrofolate reductase gene in Chinese hamster ovary B11 cells.

D. Scicchitano, A. Sitaram, W. Wang, 1995, Biochemistry.

Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.

M. Dolan, A. Pegg, D. Scicchitano, 1984, Cancer research.

DNA Damage and Transcription Elongation: Consequences and RNA Integrity

K. Dreij, D. Scicchitano, John A. Burns, 2010 .

Transcription processing at 1,N2-ethenoguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase.

S. Broyde, F. Guengerich, D. Scicchitano, 2008, Journal of molecular biology.

Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase

S. Broyde, D. Scicchitano, John A. Burns, 2008, Nucleic acids research.

Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase.

S. Broyde, L. Jia, N. Geacintov, 2008, DNA repair.

DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.

B. Hingerty, S. Broyde, N. Geacintov, 2002, Journal of molecular biology.

The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.

S. Broyde, N. Geacintov, Moinuddin A. Chowdhury, 2017, Biochemistry.

Studies of the repair of O6-alkylguanine and O4-alkylthymine in DNA by alkyltransferases from mammalian cells and bacteria.

M. Dolan, A. Pegg, D. Scicchitano, 1985, Environmental health perspectives.

O6-Methylguanine induces altered proteins at the level of transcription in human cells

K. Dreij, D. Scicchitano, John A. Burns, 2010, Nucleic acids research.

Kinetics of repair of O6-methylguanine in dna by O6-methylguanine-DNA methyltransferase in vitro and in vivo.

A. Pegg, D. Scicchitano, 1982, Biochemical and biophysical research communications.

Inhibition of O6-alkylguanine-DNA-alkyltransferase by metals.

A. Pegg, D. Scicchitano, 1987, Mutation research.

Repair of oligodeoxynucleotides containing O6-methylguanine by O6-alkylguanine-DNA-alkyltransferase.

B. Gaffney, J. Essigmann, A. Pegg, 1986, Carcinogenesis.

Repair of O6-propylguanine and O6-butylguanine in DNA by O6-alkylguanine-DNA alkyltransferases from rat liver and E. coli.

M. Dolan, A. Pegg, D. Scicchitano, 1985, Carcinogenesis.

Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene.

P. Hanawalt, D. Scicchitano, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli.

M. Dolan, A. Pegg, D. Scicchitano, 1984, Biochemical and biophysical research communications.

Increased Flexibility Enhances Misincorporation

S. Broyde, N. Geacintov, D. Scicchitano, 2007, Journal of Biological Chemistry.

The Spacious Active Site of a Y-Family DNA Polymerase Facilitates Promiscuous Nucleotide Incorporation Opposite a Bulky Carcinogen-DNA Adduct

S. Broyde, N. Geacintov, D. Scicchitano, 2004, Journal of Biological Chemistry.

Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences.

S. Broyde, N. Geacintov, D. Scicchitano, 2003, Nucleic acids research.

O6-methylguanine–induced transcriptional mutagenesis reduces p53 tumor-suppressor function

G. Margison, K. Dreij, D. Scicchitano, 2018, Proceedings of the National Academy of Sciences.

Transcription and DNA adducts: what happens when the message gets cut off?

E. Olesnicky, D. Scicchitano, A. Dimitri, 2004, DNA repair.

Construction and purification of site-specifically modified DNA templates for transcription assays.

N. Geacintov, D. Scicchitano, R. Perlow, 2003, Nucleic acids research.

Genetic instability associated with loop or stem–loop structures within transcription units can be independent of nucleotide excision repair

C. Berens, Moinuddin A. Chowdhury, D. Scicchitano, 2018, Nucleic acids research.

Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway.

Kahn Rhrissorrakrai, Kristian Dreij, Kristin C Gunsalus, 2010, Carcinogenesis.

Bacteriophage T7 RNA polymerase transcription elongation is inhibited by site-specific, stereospecific benzo[c]phenanthrene diol epoxide DNA lesions.

S. Amin, N. Geacintov, D. Scicchitano, 2001, Biochemistry.

Use of oligodeoxynucleotides containing O6-alkylguanine for the assay of O6-alkylguanine-DNA-alkyltransferase activity.

M. Dolan, A. Pegg, D. Scicchitano, 1988, Cancer research.