V. Shafirovich

发表

Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes.

S. Broyde, S. Amin, N. Geacintov, 2018, Biochemistry.

Differences in the Access of Lesions to the Nucleotide Excision Repair Machinery in Nucleosomes.

S. Broyde, N. Geacintov, V. Shafirovich, 2015, Biochemistry.

Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA*

Kent D. Sugden, J. Min, N. Geacintov, 2016, The Journal of Biological Chemistry.

Electron transfer at a distance induced by site-selective photoionization of 2-aminopurine in oligonucleotides and investigated by transient absorption techniques

V. Shafirovich, A. Dourandin, Weidong Huang, 2000 .

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion

S. Broyde, J. Min, N. Geacintov, 2020, bioRxiv.

The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion

S. Broyde, J. Min, N. Geacintov, 2020, bioRxiv.

Crossover from superexchange to hopping as the mechanism for photoinduced charge transfer in DNA hairpin conjugates.

Q. Wang, Milen Raytchev, V. Shafirovich, 2006, Journal of the American Chemical Society.

Proton-coupled electron transfer reactions at a distance in DNA duplexes

N. Geacintov, V. Shafirovich, 2004 .

One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA

J. Cadet, N. Geacintov, V. Shafirovich, 2014, International journal of radiation biology.

Remarkable Enhancement of Nucleotide Excision Repair of a Bulky Guanine Lesion in a Covalently Closed Circular DNA Plasmid Relative to the Same Linearized Plasmid.

N. Geacintov, V. Shafirovich, Marina Kolbanovskiy, 2020, Biochemistry.

Generation of guanine-amino acid cross-links by a free radical combination mechanism.

N. Geacintov, V. Shafirovich, Yuriy Uvaydov, 2014, Physical chemistry chemical physics : PCCP.

Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics.

S. Broyde, L. Jia, N. Geacintov, 2006, Biochemistry.

The Carbonate Radical Is a Site-selective Oxidizing Agent of Guanine in Double-stranded Oligonucleotides*

N. Geacintov, V. Shafirovich, A. Dourandin, 2001, The Journal of Biological Chemistry.

Intrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU).

N. Geacintov, V. Shafirovich, Conor Crean, 2008, Free radical biology & medicine.

Lifetimes and reaction pathways of guanine radical cations and neutral guanine radicals in an oligonucleotide in aqueous solutions.

N. Geacintov, V. Shafirovich, Yekaterina Rokhlenko, 2012, Journal of the American Chemical Society.

Oxidation of single-stranded oligonucleotides by carbonate radical anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines

N. Geacintov, V. Shafirovich, Yuriy Uvaydov, 2007, Nucleic acids research.

Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides.

N. Geacintov, V. Shafirovich, B. Yun, 2003, Chemical research in toxicology.

Solvent Exposure Associated with Single Abasic Sites Alters the Base Sequence Dependence of Oxidation of Guanine in DNA in GG Sequence Contexts

P. Dedon, N. Geacintov, V. Shafirovich, 2011, Chembiochem : a European journal of chemical biology.

Oxidation of guanine and 8-oxo-7,8-dihydroguanine by carbonate radical anions: insight from oxygen-18 labeling experiments.

N. Geacintov, V. Shafirovich, Conor Crean, 2005, Angewandte Chemie.

Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies.

S. Broyde, L. Jia, N. Geacintov, 2007, Biochemistry.

Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine by oxyl radicals produced by photolysis of azo compounds.

N. Geacintov, V. Shafirovich, J. Shao, 2010, Chemical research in toxicology.

Combination Reactions of Superoxide with 8-Oxo-7,8-dihydroguanine Radicals in DNA

N. Geacintov, V. Shafirovich, Yuriy Uvaydov, 2005, Journal of Biological Chemistry.

DNA Sequence Context as a Determinant of the Quantity and Chemistry of Guanine Oxidation Produced by Hydroxyl Radicals and One-electron Oxidants*

M. DeMott, P. Dedon, N. Geacintov, 2008, Journal of Biological Chemistry.

Proton-coupled electron-transfer reactions at a distance in DNA duplexes: Kinetic deuterium isotope effect

N. Geacintov, V. Shafirovich, and Alexander Dourandin, 2001 .

Stabilization of DNA hairpins by stilbene capping of the terminal base pair

V. Shafirovich, C. Richert, F. Lewis, 2006 .

5′,8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance

N. Geacintov, V. Shafirovich, Michael A. Terzidis, 2019, Cells.

Translesion synthesis past guanine(C8)-thymine(N3) intrastrand cross-links catalyzed by selected A- and Y-family polymerases.

N. Geacintov, V. Shafirovich, Yuan-Cho Lee, 2016, Molecular bioSystems.

Nitroxyl and its anion in aqueous solutions: Spin states, protic equilibria, and reactivities toward oxygen and nitric oxide

V. Shafirovich, S. Lymar, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation.

J. Cloutier, P. Dedon, N. Geacintov, 2007, Nature chemical biology.

Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.

D. Patel, L. Marky, N. Zhang, 2013, Biochemistry.

DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions.

N. Geacintov, V. Shafirovich, A. Joffe, 2003, Chemical research in toxicology.

Excision of Oxidatively Generated Guanine Lesions by Competitive DNA Repair Pathways

N. Geacintov, V. Shafirovich, 2021, International journal of molecular sciences.

Excision of Oxidatively Generated Guanine Lesions by Competing Base and Nucleotide Excision Repair Mechanisms in Human Cells.

N. Geacintov, V. Shafirovich, Marina Kolbanovskiy, 2019, Chemical research in toxicology.

Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra.

S. Broyde, L. Jia, N. Geacintov, 2009, Chemical research in toxicology.

Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods.

S. Broyde, L. Jia, N. Geacintov, 2006, Chemical research in toxicology.

Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes.

S. Broyde, L. Jia, N. Geacintov, 2005, Biochemistry.

Spiroiminodihydantoin lesions derived from guanine oxidation: structures, energetics, and functional implications.

S. Broyde, L. Jia, N. Geacintov, 2005, Biochemistry.

Combination of nitrogen dioxide radicals with 8-oxo-7,8-dihydroguanine and guanine radicals in DNA: oxidation and nitration end-products.

N. Geacintov, V. Shafirovich, Conor Crean, 2005, Journal of the American Chemical Society.

Direct spectroscopic observation of 8-oxo-7,8-dihydro-2′-deoxyguanosine radicals in double-stranded DNA generated by one-electron oxidation at a distance by 2-aminopurine radicals

J. Cadet, N. Geacintov, D. Gasparutto, 2001 .

Synthesis and fluorescence properties of a porphyrin–fullerene molecular wire

D. Schuster, J. Tomé, Sean A. Vail, 2004 .

Miscoding events during DNA synthesis past the nitration-damaged base 8-nitroguanine.

N. Geacintov, S. Shibutani, N. Suzuki, 2005, Biochemistry.

Proton-coupled electron transfer in the oxidation of guanines by an aromatic pyrenyl radical cation in aqueous solutions

N. Geacintov, V. Shafirovich, A. Dourandin, 2000 .

Dynamics and efficiency of DNA hole transport via alternating AT versus poly(A) sequences.

M. Wasielewski, Josh Vura-Weis, V. Shafirovich, 2007, Journal of the American Chemical Society.

One‐electron Oxidation of a Pyrenyl Photosensitizer Covalently Attached to DNA and Competition Between its Further Oxidation and DNA Hole Injection

P. Dedon, N. Geacintov, V. Shafirovich, 2010, Photochemistry and photobiology.

Oxidation of Guanine at a Distance in Oligonucleotides Induced by Two-Photon Photoionization of 2-Aminopurine

N. Geacintov, V. Shafirovich, A. Dourandin, 1999 .

Photoinduced oxidative DNA damage revealed by an agarose gel nicking assay: A biophysical chemistry laboratory experiment

N. Geacintov, V. Shafirovich, Carolyn Singh, 2003 .

Base and Nucleotide Excision Repair Pathways in DNA Plasmids Harboring Oxidatively Generated Guanine Lesions.

N. Geacintov, V. Shafirovich, Marina Kolbanovskiy, 2021, Chemical research in toxicology.

Absolute configurations of DNA lesions determined by comparisons of experimental ECD and ORD spectra with DFT calculations.

S. Broyde, N. Geacintov, V. Shafirovich, 2009, Chirality.

Oxidative modification of guanine bases initiated by oxyl radicals derived from photolysis of azo compounds.

N. Geacintov, V. Shafirovich, J. Shao, 2010, The journal of physical chemistry. B.

Proton-Coupled Photoinduced Electron Transfer, Deuterium Isotope Effects, and Fluorescence Quenching in Noncovalent Benzo[a]pyrenetetraol—Nucleoside Complexes in Aqueous Solutions

N. Geacintov, V. Shafirovich, S. H. Courtney, 1995 .

Photoinduced charge separation in pyrenedicarboxamide-linked DNA hairpins

M. Wasielewski, Milen Raytchev, Josh Vura-Weis, 2008, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Reactions of Small Reactive Species with DNA

N. Geacintov, V. Shafirovich, 2012 .

Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase.

S. Broyde, L. Jia, N. Geacintov, 2008, DNA repair.

The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.

S. Broyde, N. Geacintov, Moinuddin A. Chowdhury, 2017, Biochemistry.

Magnetic field effect on triplet formation as a probe of intersystem crossing mechanisms in benzo[a]pyrene diol epoxide derivative-guanosine complexes and covalent adducts

N. Geacintov, V. Shafirovich, V. A. Kuz’min, 1994 .

Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide.

N. Geacintov, V. Shafirovich, B. Yun, 2011, Chemical research in toxicology.

Oxidation of Guanine by Carbonate Radicals Derived from Photolysis of Carbonatotetramminecobalt(III) Complexes and the pH Dependence of Intrastrand DNA Cross‐Links Mediated by Guanine Radical Reactions

N. Geacintov, V. Shafirovich, B. Yun, 2008, Chembiochem : a European journal of chemical biology.

Mechanisms of oxidation of guanine in DNA by carbonate radical anion, a decomposition product of nitrosoperoxycarbonate.

Peter C Dedon, Yelena Margolin, Seog K. Kim, 2007, Chemistry.

Oxidative DNA Damage Associated with Combination of Guanine and Superoxide Radicals and Repair Mechanisms via Radical Trapping*

N. Geacintov, V. Shafirovich, Nicholas E Geacintov, 2004, Journal of Biological Chemistry.

Getting to guanine: mechanism and dynamics of charge separation and charge recombination in DNA revisited

Qiang Wang, Torsten Fiebig, Milen Raytchev, 2008, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Mechanistic Aspects of Hydration of Guanine Radical Cations in DNA

J. Cadet, N. Geacintov, V. Shafirovich, 2014, Journal of the American Chemical Society.

Inhibition of E. coli RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure—Function Relationships

S. Broyde, N. Geacintov, V. Shafirovich, 2022, International journal of molecular sciences.

Structural basis for the recognition of diastereomeric 5′,8-cyclo-2′-deoxypurine lesions by the human nucleotide excision repair system

S. Broyde, N. Geacintov, V. Shafirovich, 2014, Nucleic acids research.

Photoinduced electron transfer and strand cleavage in pyrenyl–DNA complexes and adducts

K. Solntsev, N. Geacintov, V. Shafirovich, 1998 .

The Kinetic Deuterium Isotope Effect as a Probe of a Proton Coupled Electron Transfer Mechanism in the Oxidation of Guanine by 2-Aminopurine Radicals

N. Geacintov, V. Shafirovich, A. Dourandin, 2000 .

Generation of 8‐oxo‐7,8‐dihydroguanine in G‐Quadruplexes Models of Human Telomere Sequences by One‐electron Oxidation

N. Geacintov, V. Shafirovich, Tomasz J Merta, 2018, Photochemistry and photobiology.

Removal of oxidatively generated DNA damage by overlapping repair pathways☆

N. Geacintov, V. Shafirovich, 2017, Free radical biology & medicine.

Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation

J. Cloutier, P. Dedon, N. Geacintov, 2006 .

Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide.

N. Geacintov, V. Shafirovich, A. Kolbanovskiy, 2002, Chemical research in toxicology.

Nitrogen dioxide as an oxidizing agent of 8-oxo-7,8-dihydro-2'-deoxyguanosine but not of 2'-deoxyguanosine.

J. Cadet, N. Geacintov, D. Gasparutto, 2001, Chemical research in toxicology.

Oxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: relationship between kinetics and distribution of alkali-labile lesions.

P. Dedon, N. Geacintov, V. Shafirovich, 2008, The journal of physical chemistry. B.

Methylation of 2'-deoxyguanosine by a free radical mechanism.

N. Geacintov, V. Shafirovich, Conor Crean, 2009, The journal of physical chemistry. B.

Inhibition of Excison of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Excision Repair Factor XPC-RAD23B.

N. Geacintov, V. Shafirovich, Marina Kolbanovskiy, 2020, Biochemistry.

Structural, energetic and dynamic properties of guanine(C8)–thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair

S. Broyde, N. Geacintov, V. Shafirovich, 2011, Nucleic acids research.

Proton-coupled hole hopping in nucleosomal and free DNA initiated by site-specific hole injection.

N. Geacintov, V. Shafirovich, Zhi Liu, 2012, Physical chemistry chemical physics : PCCP.

Variable inhibition of unwinding rates of DNA catalyzed by the SARS-Cov-2 (COV19) helicase nsp13 by structurally distinct single DNA lesions

N. Geacintov, V. Shafirovich, T. Lupoli, 2021, bioRxiv.

Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways*

N. Geacintov, D. Gasparutto, V. Shafirovich, 2015, The Journal of Biological Chemistry.

Multiphoton Near‐Infrared Femtosecond Laser Pulse‐Induced DNA Damage With and Without the Photosensitizer Proflavine

N. Geacintov, V. Shafirovich, A. Dourandin, 1999, Photochemistry and photobiology.

The role of one-electron reduction of lipid hydroperoxides in causing DNA damage.

N. Geacintov, V. Shafirovich, B. Yun, 2009, Chemistry.

Role of Free Radical Reactions in the Formation of DNA Damage

N. Geacintov, V. Shafirovich, 2010 .

Photogatalytic formation of a strong oxidant Os(bipy)33+ inside lipid vesicles with a high quantum yield

V. Shafirovich, E. I. Knerel’man, 1986 .

Acid–base equilibria in aqueous solutions of 2-aminopurine radical cations generated by two-photon photoionization

N. Geacintov, V. Shafirovich, A. Dourandin, 2000 .

Influence of adduct stereochemistry and hydrogen-bonding solvents on photoinduced charge transfer in a covalent benzo[a]pyrene diol epoxide-nucleoside adduct on picosecond time scales

N. Geacintov, V. Shafirovich, D. O'Connor, 1994 .

Recognition and Repair of Oxidatively Generated DNA Lesions in Plasmid DNA by a Facilitated Diffusion Mechanism.

N. Geacintov, V. Shafirovich, Marina Kolbanovskiy, 2021, Biochemical Journal.

Reversible bridge-mediated excited-state symmetry breaking in stilbene-linked DNA dumbbells.

M. Wasielewski, Milen Raytchev, Josh Vura-Weis, 2008, The journal of physical chemistry. B.

Thermodynamic profiles and nuclear magnetic resonance studies of oligonucleotide duplexes containing single diastereomeric spiroiminodihydantoin lesions.

D. Patel, L. Marky, N. Zhang, 2013, Biochemistry.

N. Geacintov, V. Shafirovich, B. Yun, 2008, Chembiochem : a European journal of chemical biology.