G. Li

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p53-independent induction of p21waf1/cip1 contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells

J. Huo, S. Metz, G. Li, 2004, Cell Death and Differentiation.

Inhibition of voltage-gated Ca2+ channels and insulin secretion in HIT cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-62: comparison with antagonists of calmodulin and L-type Ca2+ channels.

H. Hidaka, C. Wollheim, G. Li, 1992, Molecular pharmacology.

Effects of inhibitors of guanine nucleotide synthesis on membrane potential and cytosolic free Ca2+ levels in insulin-secreting cells.

S. Metz, G. Li, R. Luo, 2000, Biochemical pharmacology.

Prolonged depletion of guanosine triphosphate induces death of insulin-secreting cells by apoptosis.

M. Rabaglia, A. Kowluru, S. Metz, 1998, Endocrinology.

Inhibition of calcium-induced insulin secretion from intact HIT-T15 or INS-1 beta cells by GTP depletion.

S. Metz, G. Li, M. Meredith, 1997, Biochemical pharmacology.

Effect of disruption of actin filaments by Clostridium botulinum C2 toxin on insulin secretion in HIT-T15 cells and pancreatic islets.

C. Wollheim, K. Aktories, I. Just, 1994, Molecular biology of the cell.

Induction of sugar uptake response to insulin by serum depletion in fusing L6 myoblasts.

A. Klip, G. Li, W. Logan, 1984, The American journal of physiology.

Role of calcium ions in insulin action on hexose transport in L6 muscle cells.

A. Klip, G. Li, W. Logan, 1984, The American journal of physiology.

Insulin binding to differentiating muscle cells in culture.

A. Klip, G. Li, D. Walker, 1983, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.

Hexose transport in L6 muscle cells. Kinetic properties and the number of [3H]cytochalasin B binding sites.

A. Klip, G. Li, W. Logan, 1982, Biochimica et biophysica acta.

Effects of paxilline on K+ channels in rat mesenteric arterial cells.

G. Li, D. W. Cheung, 1999, European journal of pharmacology.

Effect of a glucokinase inhibitor on energy production and insulin release in pancreatic islets.

H. Najafi, F. Matschinsky, G. Li, 1996, The American journal of physiology.

Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin.

A. Kowluru, S. Metz, G. Li, 1997, The Journal of clinical investigation.

Use of a soluble tetrazolium compound to assay metabolic activation of intact beta cells.

S. Metz, G. Li, V. Segu, 1998, Metabolism: clinical and experimental.

Glucose regulation of glutaminolysis and its role in insulin secretion.

B. Wolf, H. Najafi, F. Matschinsky, 1999, Diabetes.

Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells.

C. Wollheim, M. Palmer, G. Li, 1994, The Biochemical journal.

Inositol tetrakisphosphate isomers and elevation of cytosolic Ca2+ in vasopressin-stimulated insulin-secreting RINm5F cells.

G. Mayr, C. Wollheim, W. Schlegel, 1992, The Journal of biological chemistry.

Potentiation of stimulus-induced insulin secretion in protein kinase C-deficient RINm5F cells.

C. Wollheim, S. Ullrich, G. Li, 1990, The Biochemical journal.

Galanin activates nucleotide‐dependent K+ channels in insulin‐secreting cells via a pertussis toxin‐sensitive G‐protein.

O. Petersen, C. Wollheim, O. Petersen, 1989, The EMBO journal.

Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells.

C. Wollheim, G. Li, W. Pralong, 1996, Cell calcium.

Stimulus-response coupling in insulin-secreting HIT cells. Effects of secretagogues on cytosolic Ca2+, diacylglycerol, and protein kinase C activity.

C. Wollheim, G. Li, R. Regazzi, 1990, The Journal of biological chemistry.

Contractile responses and signal transduction of endothelin-1 in aorta and mesenteric vasculature of adult spontaneously hypertensive rats.

E. Schiffrin, L. Deng, G. Li, 1993, Canadian journal of physiology and pharmacology.

Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins.

C. Wollheim, E. Roche, G. Li, 1993, The Biochemical journal.

Ca2+ stores in insulin-secreting cells: lack of effect of cADP ribose.

G. Rutter, C. Wollheim, G. Rutter, 1994, Cell calcium.

Different requirements for protein kinase C activation and Ca2+-independent insulin secretion in response to guanine nucleotides. Endogenously generated diacylglycerol requires elevated Ca2+ for kinase C insertion into membranes.

C. Wollheim, S. Ullrich, G. Li, 1989, The Journal of biological chemistry.

Extracellular ATP causes Ca2(+)-dependent and -independent insulin secretion in RINm5F cells. Phospholipase C mediates Ca2+ mobilization but not Ca2+ influx and membrane depolarization.

O. Petersen, C. Wollheim, G. Li, 1991, Journal of Biological Chemistry.

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines.

C B Wollheim, P. Meda, P. Halban, 1992, Endocrinology.

Evidence for differential roles of the Rho subfamily of GTP-binding proteins in glucose- and calcium-induced insulin secretion from pancreatic beta cells.

M. Rabaglia, A. Kowluru, K. Aktories, 1997, Biochemical pharmacology.

Measurement and modeling of glucose-6-phosphatase in pancreatic islets.

H. Najafi, F. Matschinsky, G. Li, 1997, American Journal of Physiology.

Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.

M. Rabaglia, S. Seavey, A. Kowluru, 1996, The Journal of clinical investigation.

Characterization of prenylcysteine methyltransferase in insulin-secreting cells.

A. Kowluru, S. Metz, G. Li, 1996, The Biochemical journal.