A. Takeiri

发表

A newly established GDL1 cell line from gpt delta mice well reflects the in vivo mutation spectra induced by mitomycin C.

Masayuki Mishima, T. Nohmi, A. Takeiri, 2006, Mutation research.

High-content imaging analyses of γH2AX-foci and micronuclei in TK6 cells elucidated genotoxicity of chemicals and their clastogenic/aneugenic mode of action

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2019, Genes and Environment.

HSP90 inhibitor CH5164840 induces micronuclei in TK6 cells via an aneugenic mechanism.

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo

D. Kirkland, A. Takeiri, H. Martus, 2022, Mutation Research/Genetic Toxicology and Environmental Mutagenesis.

Two structurally distinct inhibitors of glycogen synthase kinase 3 induced centromere positive micronuclei in human lymphoblastoid TK6 cells.

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2008, Mutation research.

Advantages of evaluating γH2AX induction in non-clinical drug development

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2018, Genes and Environment.

Whole cell-ELISA to measure the gammaH2AX response of six aneugens and eight DNA-damaging chemicals.

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2010, Mutation research.

Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS

Masayuki Mishima, Tsuneo Hashizume, M. Honma, 2021, Genes and Environment.

Mutation Spectra in Cisplatin- and Transplatin-treated GDL1 Cells Clarified the Different Mode of Action of These Compounds in Mammalian Cells

Masayuki Mishima, T. Nohmi, A. Takeiri, 2007 .

High-content imaging analyses of γH2AX-foci and micronuclei in TK6 cells elucidated genotoxicity of chemicals and their clastogenic/aneugenic mode of action

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2019, Genes and Environment.

Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene‐induced genotoxicity in vivo

K. Jishage, Masayuki Mishima, T. Nohmi, 2017, Environmental and molecular mutagenesis.

Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D3 analog, pefcalcitol

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2017, Genes and Environment.

In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C.

K. Jishage, Masayuki Mishima, M. Yamada, 2014, DNA repair.

MHC-associated peptide proteomics enabling highly sensitive detection of immunogenic sequences for the development of therapeutic antibodies with low immunogenicity

A. Takeiri, A. Maeda, F. Mimoto, 2018, mAbs.

Lack of Mutagenicity of SMD-502, a New Vitamin D3 Analog for Topical Application, in Skin and Liver of gpt delta Transgenic Mice and in GDL1 Cells

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2012 .

Molecular characterization of mitomycin C-induced large deletions and tandem-base substitutions in the bone marrow of gpt delta transgenic mice.

O. Ueda, Hiroshi Suzuki, Masayuki Mishima, 2003, Chemical research in toxicology.

New DNA probes to detect aneugenicity in rat bone marrow micronucleated cells by a pan-centromeric FISH analysis.

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2013, Mutation research.

Advantages of evaluating γH2AX induction in non-clinical drug development

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2018, Genes and Environment.

The predominant role of apoptosis in γH2AX formation induced by aneugens is useful for distinguishing aneugens from clastogens.

Masayuki Mishima, A. Takeiri, A. Harada, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

Preclinical in vitro evaluation of immune suppression induced by GYM329, Fc-engineered sweeping antibody.

Masayuki Mishima, A. Takeiri, A. Harada, 2023, The Journal of toxicological sciences.

Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4+ T cell interleukin-2 secretion

Masayuki Mishima, Yukari Nishito, A. Takeiri, 2023, mAbs.

New DNA probes to detect aneugenicity in rat bone marrow micronucleated cells by a pan-centromeric FISH analysis.

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2013, Mutation research.

Fluorescent dye-based simple staining for in vivo micronucleus test with flow cytometer.

Masayuki Mishima, A. Takeiri, Kenji Tanaka, 2013, Mutation research.