J. Jansen

发表

Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.

L. Mullenders, H. Vrieling, F. D. de Gruijl, 2009, DNA repair.

Send in the clamps: control of DNA translesion synthesis in eukaryotes.

N. de Wind, M. Fousteri, J. Jansen, 2007, Molecular cell.

Methyl methanesulfonate-induced hprt mutation spectra in the Chinese hamster cell line CHO9 and its xrcc1-deficient derivative EM-C11.

H. Vrieling, A. V. van Zeeland, J. Jansen, 1998, Mutation research.

Analysis of mutant frequencies and mutation spectra in hMTH1 knockdown TK6 cells exposed to UV radiation.

L. Mullenders, M. Harms-Ringdahl, F. D. de Gruijl, 2013, Mutation research.

Alkylpurine–DNA–N-Glycosylase Knockout Mice Show Increased Susceptibility to Induction of Mutations by Methyl Methanesulfonate

D. Cooper, G. Margison, A. V. van Zeeland, 1998, Molecular and Cellular Biology.

Molecular analysis of hprt gene mutations in skin fibroblasts of rats exposed in vivo to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.

H. Vrieling, A. V. van Zeeland, P. Lohman, 1994, Cancer research.

DNA mismatch repair-dependent DNA damage responses and cancer.

N. de Wind, J. Jansen, Robbert Ijsselsteijn, 2020, DNA repair.

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

N. de Wind, J. Jansen, H. Jacobs, 2005, Nucleic acids research.

Roles of mutagenic translesion synthesis in mammalian genome stability, health and disease.

N. de Wind, J. Jansen, Anastasia Tsaalbi-Shtylik, 2015, DNA repair.

The Rev1 translesion synthesis polymerase has multiple distinct DNA binding modes.

N. de Wind, G. Siegal, K. Kamiya, 2011, DNA repair.

The gene encoding hypoxanthine-guanine phosphoribosyltransferase as target for mutational analysis: PCR cloning and sequencing of the cDNA from the rat.

H. Vrieling, A. V. van Zeeland, J. Jansen, 1992, Mutation research.

Different sets of translesion synthesis DNA polymerases protect from genome instability induced by distinct food-derived genotoxins.

N. de Wind, F. Delbos, Piya Temviriyanukul, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Transcription and replication: Far relatives make uneasy bedfellows

N. de Wind, G. Hendriks, L. Mullenders, 2010, Cell cycle.

Transcription and replication

G. Hendriks, J. Jansen, N. Wind, 2010 .

Molecular dosimetry of 7-alkyl- and O6-alkylguanine in DNA by electrochemical detection.

A. V. van Zeeland, A. de Groot, J. Jansen, 1994, Mutation research.

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance.

N. de Wind, C. Reynaud, P. V. D. van den Berk, 2011, DNA repair.

Mammalian polymerase zeta is essential for post-replication repair of UV-induced DNA lesions.

N. de Wind, G. Hendriks, Himabindu Gali, 2009, DNA repair.

Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells.

N. de Wind, G. Hendriks, L. Mullenders, 2008, DNA repair.

Temporally distinct translesion synthesis pathways for ultraviolet light-induced photoproducts in the mammalian genome.

N. de Wind, F. Delbos, Piya Temviriyanukul, 2012, DNA repair.

Transcription-coupled repair and apoptosis provide specific protection against transcription-associated mutagenesis by ultraviolet light

N. de Wind, G. Hendriks, L. Mullenders, 2010, Transcription.

Mechanisms and biomarkers of genotoxicity. Molecular dosimetry of chemical mutagens.

H. Vrieling, A. V. van Zeeland, A. de Groot, 1995, Toxicology Letters.

GEnOME InSTAbILITy FOLLOwInG MITOTIC TRAnSMISSIOn OF unREPLICATEd dnA LESIOnS

Piya Temviriyanukul, J. Jansen, Anastasia Tsaalbi-Shtylik, 2014 .

Nucleotide excision repair modulates the cytotoxic and mutagenic effects of N-n-butyl-N-nitrosourea in cultured mammalian cells as well as in mouse splenocytes in vivo.

A. Tates, L. Mullenders, H. Vrieling, 1999, Mutagenesis.

in hypermutating immunoglobulin genes in Rev1-defi cient mice

J. Jansen, P. Berk, H. Jacobs, 2006 .

Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions

N. de Wind, G. Hendriks, Piya Temviriyanukul, 2015, The Journal of cell biology.

Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.

A. Tates, L. Mullenders, H. Vrieling, 1998, Cancer research.

Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.

A. Tates, H. Vrieling, A. V. van Zeeland, 1995, Cancer research.

AT base pairs are the main target for mutations at the hprt locus of rat skin fibroblasts exposed in vitro to the monofunctional alkylating agent N-ethyl-N-nitrosourea.

H. Vrieling, A. V. van Zeeland, J. Jansen, 1994, Mutagenesis.

Mutagenic replication: target for tumor therapy?

J. Jansen, N. Wind, 2019, Cell Research.

Synthesis, characterization, crystal structures and magnetic properties of di- and polynuclear bis(μ-3-pyridin-2-yl-1,2,4- triazolato)copper(II) compounds containing N-methylimidazole, pyrazole or 4,4′-bipyridine as co-ligands

A. Spek, J. G. Haasnoot, J. Jansen, 1993 .

Crystal structures, electrical conductivity and band-structure calculations of three new [cation][Ni(C3S5)2]2 compounds

A. Spek, D. Reefman, J. G. Haasnoot, 1992 .

Induction of hprt gene mutations in splenic T-lymphocytes from the rat exposed in vivo to DNA methylating agents is correlated with formation of O6-methylguanine in bone marrow and not in the spleen.

A. Tates, H. Vrieling, A. V. van Zeeland, 1996, Carcinogenesis.

Formation and persistence of DNA adducts in pouch skin fibroblasts and liver tissue of rats exposed in vivo to the monofunctional alkylating agents N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.

H. Vrieling, A. V. van Zeeland, A. de Groot, 1994, Mutation research.

Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light

N. de Wind, F. Delbos, C. Reynaud, 2014, Nucleic acids research.

nitrosourea N-Ethyl-N-nitrosourea , or N-( 2-Hydroxyethyl )-N Ethylmethanesulfonate , to in Vivo Mutagenesis in T-Lymphocytes of Rats Exposed hprt-Alkylguanine in 6 O Marked Differences in the Role of Updated

A. Tates, H. Vrieling, J. Jansen, 2006 .

Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents.

A. V. van Zeeland, J. Jansen, A. A. Zeeland, 1997, Mutagenesis.

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress

Benjamin P. C. Chen, N. de Wind, E. Friedberg, 2015, Nucleic acids research.

Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice

N. de Wind, P. V. D. van den Berk, J. Jansen, 2006, The Journal of experimental medicine.

Biological functions of translesion synthesis proteins in vertebrates.

N. de Wind, J. Jansen, 2003, DNA repair.

De novo mutations in PLXND1 and REV3L cause Möbius syndrome

A. Hoischen, N. de Wind, D. Schubert, 2015, Nature Communications.

Reduced methylation-induced mutagenesis in rat splenocytes in vivo by sub-chronic low dose exposure to N-metyl-N-nitrosourea.

L. Mullenders, H. van Steeg, A. V. van Zeeland, 2008, Mutation research.

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage

N. de Wind, P. V. D. van den Berk, J. Jansen, 2014, Nucleic acids research.

Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

N. de Wind, J. Jonkers, F. D. de Gruijl, 2009, Proceedings of the National Academy of Sciences.

Separate Domains of Rev1 Mediate Two Modes of DNA Damage Bypass in Mammalian Cells

N. de Wind, Z. Livneh, A. Hendel, 2009, Molecular and Cellular Biology.

Nucleotide excision repair in differentiated cells.

L. Mullenders, H. Vrieling, A. V. van Zeeland, 2007, Mutation research.

The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage.

L. Mullenders, H. Vrieling, A. V. van Zeeland, 1999, Nucleic acids research.

Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A

N. de Wind, L. Mullenders, J. Moser, 2014, Nucleic acids research.

Detection of point mutations in T lymphocytes.

A. Tates, H. Vrieling, A. V. van Zeeland, 1995, Clinical chemistry.

Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase.

H. Vrieling, A. V. van Zeeland, J. Jansen, 1999, Mutation research.

Supplemental Information Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis

Harry Vrieling, Giel Hendriks, G. Pfeifer, 2009 .

Induction of mismatch repair deficiency, compromised DNA damage signaling and compound hypermutagenesis by a dietary mutagen in a cell-based model for Lynch syndrome

N. de Wind, J. Jansen, M. Drost, 2021, Carcinogenesis.

When mismatch repair met translesion synthesis

N. de Wind, J. Jansen, Anastasia Tsaalbi-Shtylik, 2015, Cell cycle.

Post-translesion synthesis repair

N. de Wind, J. Jansen, Anastasia Tsaalbi-Shtylik, 2015, Oncotarget.

Transcription-coupled repair and apoptosis provide specific protection against transcription-associated mutagenesis by ultraviolet light

N. de Wind, G. Hendriks, L. Mullenders, 2010, Transcription.

Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis

G. Hendriks, L. Mullenders, H. Vrieling, 2010, Current Biology.

Brief Definitive Report Strand-biased Defect in C/g Transversions in Hypermutating Immunoglobulin Genes in Rev1-defi Cient Mice

N. de Wind, P. V. D. van den Berk, J. Jansen, 2022 .

Separate Domains of Rev1 Mediate Two Modes of DNA Damage Bypass in Mammalian Cells

N. de Wind, Z. Livneh, G. Hendriks, 2009, Molecular and Cellular Biology.