David M Williams

发表

A novel DNA damage recognition protein in Schizosaccharomyces pombe

M. Santibanez-Koref, G. Margison, Ghazala Begum, 2006, Nucleic acids research.

The effect of tautomeric constant on the specificity of nucleotide incorporation during DNA replication: support for the rare tautomer hypothesis of substitution mutagenesis.

H. Adams, D. Hornby, David M Williams, 2003, Journal of molecular biology.

Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations

G. Margison, M. Tsunoda, David M Williams, 2013, Nucleic acids research.

Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.

J. Tainer, M. Santibanez-Koref, G. Margison, 2012, Molecular cell.

Synthesis of Nb(O2H5C7)3Y (Y: O, S and Se): Crystal Structure of Oxo-tris(tropolonato)niobium(V) Monohydrate: a Seven Coordinate Monomer Containing a Terminal Nb=O Bond.

M. Drew, David M Williams, D. A. Rice, 1987 .

Synthesis of Nb(O2H5C7)3Y (Y = O, S and Se): Crystal structure of oxo-tris-(tropolonato)niobium(V) monohydrate: a seven coordinate monomer containing a terminal NbO bond

M. Drew, David M Williams, D. A. Rice, 1986 .

The synthesis and properties of oligoribonucleotide-spermine conjugates.

J. Grasby, David M Williams, Andrew Marsh, 2004, Organic & biomolecular chemistry.

Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

J. Chin, K. J. Patel, Koichi Sato, 2020, Nature.

Convenient and Efficient Syntheses of Oligodeoxyribonucleotides Containing O 6-(Carboxymethyl)Guanine and O 6-(4-Oxo-4-(3-Pyridyl)Butyl)Guanine

G. Margison, A. Povey, A. Watson, 2012, Nucleosides, nucleotides & nucleic acids.

Synthesis of Suitably-Protected Phosphoramidites of 2′-Fluoro-2′-Deoxyguanosine and 2′-Amino-2′-Deoxyguanosine for Incorporation Into Oligoribonucleotides

David M Williams, F. Eckstein, F. Benseler, 1992 .

Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation–π interactions

C. Hunter, J. Tainer, G. Margison, 2012, Proceedings of the National Academy of Sciences.

Alkylated DNA damage flipping bridges base and nucleotide excision repair

John A Tainer, Oliver Fleck, J. Tainer, 2009, Nature.

The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine.

H. Adams, G. Margison, David M Williams, 2006, Organic & biomolecular chemistry.

The syntheses of tricyclic analogues of O6-methylguanine.

David M Williams, David M. Hammond, D. Edmont, 2003, Organic & biomolecular chemistry.

Synthesis of Tricyclic Nucleoside Analogue of O6-Methyl-2'-Deoxyguanosine

David M Williams, K. Abdu, David M. Williams, 2013 .

Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of O6-methylguanine and their recognition by MGMT and Atl1

Timothy D. Craggs, G. Margison, A. Povey, 2020, Nucleosides, nucleotides & nucleic acids.

The Synthesis and Properties of Tricyclic Analogues of S 6–Methylthioguanineand O 6-Methylguanine

H. Adams, G. Margison, David M Williams, 2007, Nucleosides, nucleotides & nucleic acids.

A new and versatile synthesis of 5-substituted pyrrolo[2,3-d]pyrimidines

David M Williams, D. Edmont, David M. Williams, 2000 .

Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT)

G. Margison, Nicola Glynn, David M Williams, 2006, Nucleic acids research.

Some pyrrolopyrimidine chemistry directed to the synthesis of tricyclic purine analogues

David M Williams, Daniel M. Brown, David M. Williams, 1995 .

2'-Fluoro- and 2'-amino-2'-deoxynucleoside 5'-triphosphates as substrates for T7 RNA polymerase.

D. Williams, David M Williams, F. Eckstein, 1992, Biochemistry.

Novel syntheses of (Z)-alkene and alkane base-modified nucleosides.

J. Grasby, S. E. Lee, David M Williams, 2000 .

7,8-Dihydropyrido[2,3-d]pyrimidin-2-one; a bicyclic cytosine analogue capable of enhanced stabilisation of DNA duplexes.

N. Buurma, David M Williams, T. Shibata, 2006, Chemical communications.

Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation

B. F. Taylor, Nicholas H Williams, David M Williams, 2005, Nucleic acids research.

Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR.

J. Grasby, D. Williams, N. Mignet, 2001, Nucleic acids research.

Novel Syntheses of (Z)‐Alkene and Alkane Based‐Modified Nucleosides.

J. Grasby, S. E. Lee, David M Williams, 2000 .

Properties of 2'-fluorothymidine-containing oligonucleotides: interaction with restriction endonuclease EcoRV.

D. Williams, David M Williams, F. Eckstein, 1991, Biochemistry.

Flap endonucleases pass 5′-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5′-ends

J. Tainer, L. Finger, J. Exell, 2012, Nucleic acids research.

An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues.

D. M. Brown, M. Zaccolo, E. Gherardi, 1996, Journal of molecular biology.

O⁶-carboxymethylguanine in DNA forms a sequence context-dependent wobble base-pair structure with thymine.

G. Margison, M. Tsunoda, David M Williams, 2014, Acta crystallographica. Section D, Biological crystallography.

Incorporation of a complete set of deoxyadenosine and thymidine analogues suitable for the study of protein nucleic acid interactions into oligodeoxynucleotides. Application to the EcoRV restriction endonuclease and modification methylase.

D. Williams, F. Seela, David M Williams, 1990, Biochemistry.

Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links

K. J. Patel, L. Finger, J. Grasby, 2022, Journal of the American Chemical Society.

The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase

G. Margison, A. Povey, C. Eyers, 2013, Nucleic acids research.

The reactions of tetrahydrothiophene (tht) with tribromosulphidoniobium(V) and trichlorosulphidoniobium(V) and the crystal structures of three of the products Nb2Cl4S3·4tht, Nb2Br4S3·4tht, and NbBr3S·2tht

M. Drew, David M Williams, D. A. Rice, 1983 .