Maurizio Botta

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Novel Virtual Screening Protocol Based on the Combined Use of Molecular Modeling and Electron-Ion Interaction Potential Techniques To Design HIV-1 Integrase Inhibitors

Cristina Tintori, Fabrizio Manetti, Nevena Veljkovic, 2007, J. Chem. Inf. Model..

Research on anti-HIV-1 agents. Investigation on the CD4-Suradista binding mode through docking experiments

Fabrizio Manetti, Maurizio Botta, Federico Corelli, 2000, J. Comput. Aided Mol. Des..

Lennard-Jones Potential and Dummy Atom Settings to Overcome the AUTODOCK Limitation in Treating Flexible Ring Systems

Maurizio Botta, Stefano Forli, M. Botta, 2007, J. Chem. Inf. Model..

Insight into the Allosteric Inhibition of Abl Kinase

Cristina Tintori, Maurizio Botta, Anna Lucia Fallacara, 2014, J. Chem. Inf. Model..

Highlighting Medicinal Chemistry in Italy Special Issue.

Maurizio Botta, 2019, ACS medicinal chemistry letters.

Molecular Dynamics and DFT Study on HIV-1 Nucleocapsid Protein-7 in Complex with Viral Genome

Fabrizio Manetti, Maurizio Botta, Mattia Mori, 2010, J. Chem. Inf. Model..

A Genetic-Function-Approximation-Based QSAR Model for the Affinity of Arylpiperazines toward alpha1 Adrenoceptors

Fabrizio Manetti, Maurizio Botta, Matteo Magnani, 2006, J. Chem. Inf. Model..

Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions

Maurizio Botta, Mattia Mori, Ylenia Cau, 2015, J. Chem. Inf. Model..

Protein Kinases: Docking and Homology Modeling Reliability

Maurizio Botta, Tiziano Tuccinardi, Antonio Giordano, 2010, J. Chem. Inf. Model..

Computer-assisted perception of similarity using the Chiron program: a powerful tool for the analysis and prediction of biogenetic patterns

Maurizio Botta, Stephen Hanessian, Benoit Larouche, 1992, J. Chem. Inf. Comput. Sci..

Variable selection and specification of robust QSAR models from multicollinear data: arylpiperazinyl derivatives with affinity and selectivity for α2-adrenoceptors

Maurizio Botta, Martyn G. Ford, David W. Salt, 2004, J. Comput. Aided Mol. Des..

Preface [Neglected Diseases: Extensive Space for Modern Drug Discovery]

Maurizio Botta, Francesco Orofino, 2018 .

Developing Pyrrole‐Derived Antimycobacterial Agents: a Rational Lead Optimization Approach

Fabrizio Manetti, Maurizio Botta, Mariangela Biava, 2011, ChemMedChem.

Targets Looking for Drugs: A Multistep Computational Protocol for the Development of Structure-Based Pharmacophores and Their Applications for Hit Discovery

Cristina Tintori, Fabrizio Manetti, Maurizio Botta, 2008, J. Chem. Inf. Model..

A Combination of Molecular Dynamics and Docking Calculations to Explore the Binding Mode of ADS-J1, a Polyanionic Compound Endowed with Anti-HIV-1 Activity

Cristina Tintori, Fabrizio Manetti, Silvio Massa, 2006, J. Chem. Inf. Model..

Chapter 11:Application of Molecular Modelling to Speed-up the Lead Discovery Process

Maurizio Botta, Anna Lucia Fallacara, Iuni M. L. Trist, 2017 .

Unconventional Plasticity of HIV-1 Reverse Transcriptase: How Inhibitors Could Open a Connection "Gate" between Allosteric and Catalytic Sites

Maurizio Botta, Marco Radi, Luca Bellucci, 2013, J. Chem. Inf. Model..

Construction and Validation of a RET TK Catalytic Domain by Homology Modeling

Fabrizio Manetti, Maurizio Botta, Tiziano Tuccinardi, 2007, J. Chem. Inf. Model..

Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors

Cristina Tintori, Maurizio Botta, Giovanni Maga, 2015, J. Chem. Inf. Model..

SMALL MOLECULES SOLVING BIG PROBLEMS: PRESENT AND FUTURE OF DRUG DISCOVERY

Maurizio Botta, Anna Lucia Fallacara, Iuni Margaret Laura Tris, 2018, Journal of the Siena Academy of Sciences.

Predicting the Binding Mode of Known NCp7 Inhibitors To Facilitate the Design of Novel Modulators

Fabrizio Manetti, Maurizio Botta, Mattia Mori, 2011, J. Chem. Inf. Model..

Structure, Function, Involvement in Diseases and Targeting of 14-3-3 Proteins: An Update.

Maurizio Botta, Mattia Mori, Ylenia Cau, 2017, Current medicinal chemistry.

A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors.

Fabrizio Manetti, Maurizio Botta, Stefano Forli, 2006, Journal of medicinal chemistry.

Molecular modeling of azole antifungal agents active against Candida albicans. 1. A comparative molecular field analysis study.

Silvio Massa, Maurizio Botta, Federico Corelli, 1996 .

Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity.

Fabrizio Manetti, Maurizio Botta, Paola Molicotti, 2006, Journal of medicinal chemistry.

A Multidisciplinary Approach for the Identification of Novel HIV‐1 Non‐Nucleoside Reverse Transcriptase Inhibitors: S‐DABOCs and DAVPs

Maurizio Botta, Marco Radi, Mercedes Armand-Ugón, 2008, ChemMedChem.

Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin.

Fabrizio Manetti, Maurizio Botta, Claudio Battilocchio, 2010, Bioorganic & medicinal chemistry.

A Multidisciplinary Research on Verbesina caracasana

Maurizio Botta, Bruno Botta, G. Delle Monache, 1997 .

Molecular basis for the binding of competitive inhibitors of maize polyamine oxidase.

Fabrizio Manetti, Maurizio Botta, Fabio Polticelli, 2004, Biochemistry.

Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses.

Maurizio Botta, Mattia Mori, Giorgio Maccari, 2010, Chemistry & biology.

1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings.

Fabrizio Manetti, Maurizio Botta, Mariangela Biava, 2008, Journal of medicinal chemistry.

Discovery of small molecule HIV-1 integrase dimerization inhibitors.

Cristina Tintori, Silvio Massa, Zeger Debyser, 2012, Bioorganic & medicinal chemistry letters.

Design and Synthesis of Thiadiazoles and Thiazoles Targeting the Bcr‐Abl T315I Mutant: from Docking False Positives to ATP‐Noncompetitive Inhibitors

Fabrizio Manetti, Maurizio Botta, Marco Radi, 2010, ChemMedChem.

Application of Pharmacophore Models in Medicinal Chemistry

Fabrizio Manetti, Maurizio Botta, Andrea Tafi, 2006 .

Small molecules modulation of 14-3-3 protein-protein interactions.

Maurizio Botta, Mattia Mori, G. Vignaroli, 2013, Drug discovery today. Technologies.

N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds.

Fabrizio Manetti, Maurizio Botta, Silvia Schenone, 2008, Bioorganic & medicinal chemistry letters.

Computational studies of the interaction between the HIV‐1 integrase tetramer and the cofactor LEDGF/p75: Insights from molecular dynamics simulations and the Informational spectrum method

Cristina Tintori, Nevena Veljkovic, Veljko Veljkovic, 2010, Proteins.

An update on dual Src/Abl inhibitors.

Maurizio Botta, Silvia Schenone, Francesca Musumeci, 2012, Future medicinal chemistry.

Small Molecule Inhibitors Targeting HIV‐1 Reverse Transcriptase Dimerization

Fabrizio Manetti, Maurizio Botta, Valentina Corradi, 2008, Chembiochem : a European journal of chemical biology.

1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation.

Fabrizio Manetti, Maurizio Botta, Mariangela Biava, 2009, European journal of medicinal chemistry.

High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction.

Cristina Tintori, Maurizio Botta, Anna Lucia Fallacara, 2014, Bioorganic & medicinal chemistry letters.

Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.

Fabrizio Manetti, Maurizio Botta, Valentina Corradi, 2011, Bioorganic & medicinal chemistry letters.

Computer-Assisted Perception of Similarity Using the Chiron Program: A Powerful Tool for the Analysis and Prediction of Biogenetic Patterns.

Maurizio Botta, Stephen Hanessian, Benoit Larouche, 1993 .

Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors.

Fabrizio Manetti, Maurizio Botta, Silvia Schenone, 2009, Bioorganic & medicinal chemistry letters.

3D QSAR Models Built on Structure‐Based Alignments of Abl Tyrosine Kinase Inhibitors

Fabrizio Manetti, Maurizio Botta, Silvia Schenone, 2009, ChemMedChem.

Synthetic SRC-kinase domain inhibitors and their structural requirements.

Fabrizio Manetti, Maurizio Botta, Silvia Schenone, 2007, Anti-cancer agents in medicinal chemistry.

Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein-protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis.

Fabrizio Manetti, Maurizio Botta, Valentina Corradi, 2010, Bioorganic & medicinal chemistry letters.