S. Fling

发表

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

Salil S. Bhate, Garry P. Nolan, G. Nolan, 2020, Nature Communications.

A new data-driven cell population discovery and annotation method for single-cell data, FAUST, reveals correlates of clinical response to cancer immunotherapy

J. Taube, R. Gottardo, Greg Finak, 2019, bioRxiv.

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Pham Phung, Terri Wrin, Dennis R. Burton, 2009, Science.

Broad neutralization coverage of HIV by multiple highly potent antibodies

Pham Phung, Terri Wrin, Chi-Huey Wong, 2011, Nature.

Gene expression markers of Tumor Infiltrating Leukocytes

Patrick Danaher, Steven P. Fling, Andrew B. White, 2016, Journal of Immunotherapy for Cancer.

CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis.

M. Starnbach, L. Steele, S. D’Orazio, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Differential APC requirements of self- and nonself-reactive T cells and T cell hybridomas specific for retinal S-antigen.

S. Fling, D. Gregerson, S. Prasad, 1997, Journal of autoimmunity.

Multiple, autoreactive TCR V beta genes utilized in response to a small pathogenic peptide of an autoantigen in EAU.

D. Gold, S. Fling, D. Gregerson, 1992, Cellular immunology.

Tuberculosis following PD-1 blockade for cancer immunotherapy

J. Nieva, D. Barber, P. Nghiem, 2019, Science Translational Medicine.

Pembrolizumab in mycosis fungoides with PD-L1 structural variants.

Sebastian Fernandez-Pol, H. Stehr, J. Zehnder, 2021, Blood advances.

Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.

J. Taube, T. Olencki, E. Lipson, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Identification of an HIV-1 Clade A Envelope That Exhibits Broad Antigenicity and Neutralization Sensitivity and Elicits Antibodies Targeting Three Distinct Epitopes

Sergei L. Kosakovsky Pond, D. Burton, D. Montefiori, 2013, Journal of Virology.

HLA-DMA and DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

B. Arp, S. Fling, D. Pious, 1994 .

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

B. Arp, S. Fling, D. Pious, 1994, Nature.

Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets

P. Danaher, D. Bedognetti, J. Beechem, 2020, Nature Cancer.

Novel Mutants Define Genes Required for the Expression of Human Histocompatibility Leukocyte Antigen DM: Evidence for Loci on Human Chromosome 6p

B. Arp, S. Fling, K. Muczynski, 1997, The Journal of experimental medicine.

Three-year survival, correlates and salvage therapies in patients receiving first-line pembrolizumab for advanced Merkel cell carcinoma

J. Taube, T. Olencki, E. Lipson, 2021, Journal for ImmunoTherapy of Cancer.

Mycobacterium tuberculosis Protects Against Challenge with Vaccination with the T Cell Antigen Mtb 8.4

J. Flynn, R. Coler, S. Reed, 2001 .

Vaccination with the T Cell Antigen Mtb 8.4 Protects Against Challenge with Mycobacterium tuberculosis1

J. Flynn, R. Coler, S. Reed, 2001, The Journal of Immunology.

Assignment of several epitopes to cyanogen bromide peptides of bovine retinal S-antigen by immunoblotting with peptide-specific antibodies.

S. Fling, D. Gregerson, V. Knospe, 1988, Current eye research.

IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC)

H. Maecker, J. Seigne, L. Appleman, 2021, Journal for ImmunoTherapy of Cancer.

The use of synthetic peptides in the study of experimental autoimmune uveitis.

S. Fling, L. A. Donoso, D. Gregerson, 1990, Current eye research.

Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy

S. Lewin, J. Lifson, R. Sékaly, 2022, Science Translational Medicine.

Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea.

S. Fling, S P Fling, D S Gregerson, 1986, Analytical biochemistry.

Identification of a uveitogenic cyanogen bromide peptide of bovine retinal S‐antigen and preparation of a uveitogenic, peptide‐specific T cell line

S. Fling, D. Gregerson, W. F. Obritsch, 1987, European journal of immunology.

Characterization of immunologically active cyanogen bromide peptide fragments of bovine and human retinal S-antigen.

S. Fling, R. Wohlhueter, D. Gregerson, 1986, Experimental eye research.

Effect of CD4+ T cell count on treatment-emergent adverse events among patients with and without HIV receiving immunotherapy for advanced cancer

J. Martinez-Picado, R. Ramaswami, S. Fling, 2022, Journal for ImmunoTherapy of Cancer.

The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.

T. J. Murray, S. Fling, C. Cluff, 2008, Bioorganic & medicinal chemistry letters.

Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors

V. Velcheti, M. Ernstoff, Jeffrey S. Miller, 2018, Clinical Cancer Research.

PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.

Drew M. Pardoll, Janis M. Taube, Paul T. Nghiem, 2016, The New England journal of medicine.

Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab

Ludmila V. Danilova, J. Taube, E. Lipson, 2018, Journal of Immunotherapy for Cancer.

PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy

R. Gottardo, S. Riddell, B. Dréno, 2020, Journal for ImmunoTherapy of Cancer.

Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

H. Kluger, S. Topalian, P. Nghiem, 2018, Journal of Immunotherapy for Cancer.

Cell-based gene therapy experiments in murine experimental autoimmune encephalomyelitis

L. Weiner, S. Fling, J. Du, 2005, Gene Therapy.

Single-cell RNA-sequencing reveals predictive features of response to pembrolizumab in Sézary syndrome

Tianying Su, S. Fling, N. Ramchurren, 2022, medRxiv.

A Synthetic TLR4 Antagonist Has Anti-Inflammatory Effects in Two Murine Models of Inflammatory Bowel Disease 1

D. Persing, R. Hershberg, R. Ulevitch, 2005, The Journal of Immunology.

New interpretable machine-learning method for single-cell data reveals correlates of clinical response to cancer immunotherapy

Greg Finak, Raphael Gottardo, Nina Bhardwaj, 2021, Patterns.

New interpretable machine learning method for 1 single-cell data reveals correlates of clinical response to 2 cancer immunotherapy

Greg Finak, Raphael Gottardo, Evan Greene, 2019 .

Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced Cancer-A Phase 1 Study.

M. Sznol, M. Ernstoff, L. Fong, 2019, JAMA oncology.

The Murine Cytomegalovirus Immunomodulatory Gene m152 Prevents Recognition of Infected Cells by M45-Specific CTL But Does Not Alter the Immunodominance of the M45-Specific CD8 T Cell Response In Vivo1

U. Koszinowski, M. Munks, S. Fling, 2002, The Journal of Immunology.

Human CD8+ T Cells Recognize the 60-kDa Cysteine-Rich Outer Membrane Protein from Chlamydia trachomatis1

S. Fling, K. Grabstein, M. Alderson, 2004, The Journal of Immunology.

Unresponsiveness to self-peptides of S-antigen in EAU: an overview of recent results.

L. Donoso, D. Gold, S. Fling, 1992, Current eye research.

Pembrolizumab in Relapsed and Refractory Mycosis Fungoides and Sézary Syndrome: A Multicenter Phase II Study.

H. Kohrt, R. Pierce, H. Maecker, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Classically Restricted Human CD8+ T Lymphocytes Derived from Mycobacterium tuberculosis-Infected Cells: Definition of Antigenic Specificity1

S. Reed, S. Fling, K. Grabstein, 2001, The Journal of Immunology.

An Inclusion Membrane Protein from Chlamydia trachomatis Enters the MHC Class I Pathway and Stimulates a CD8+ T Cell Response 1

M. Starnbach, S. Fling, M. Alderson, 2003, The Journal of Immunology.

A radiosensitive APC activity dissociates IL-2 secretion and activation-induced cell death by autoreactive T cell hybridomas.

S. Fling, D. Gregerson, S. Prasad, 1995, International Immunology.

The Murine Cytomegalovirus

U. Koszinowski, M. Munks, S. Fling, 2002 .

T Cell Response In Vivo Immunodominance of the M 45-Specific CD 8 CTL But Does Not Alter the Recognition of Infected Cells by M 45-Specific Prevents m 152 Immunomodulatory Gene The Murine Cytomegalovirus

U. Koszinowski, M. Munks, S. Fling, 2002 .

PHASE I TRIAL OF ALT-803, A NOVEL RECOMBINANT INTERLEUKIN-15 COMPLEX, IN PATIENTS WITH ADVANCED SOLID TUMORS

V. Velcheti, M. Ernstoff, Jeffrey S. Miller, 2018 .

In vitro unresponsiveness to autologous sequences of the immunopathogenic autoantigen, S-antigen.

L. Donoso, S. Fling, D. Gregerson, 1991, Journal of immunology.

Preparation of overlapping peptides of bovine retinal S-antigen and their localization by immunoblotting with peptide-specific antibodies.

S. Fling, D. Gregerson, V. Knospe, 1988, Current eye research.

Durable Responses with Pembrolizumab in Relapsed/Refractory Mycosis Fungoides and Sézary Syndrome: Final Results from a Phase 2 Multicenter Study

H. Kohrt, H. Maecker, J. Yearley, 2018, Blood.

Pembrolizumab for Treatment of Relapsed/Refractory Mycosis Fungoides and Sezary Syndrome: Clinical Efficacy in a Citn Multicenter Phase 2 Study

Ash A. Alizadeh, H. Kohrt, H. Maecker, 2016 .

Identification of T cell recognition sites in S-antigen: dissociation of proliferative and pathogenic sites.

L. Donoso, S. Fling, D. Gregerson, 1989, Cellular immunology.

Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses

P. Danaher, C. Morrison, Song Liu, 2022, Science Translational Medicine.

A Phase II Randomized Study of CDX-1401, a Dendritic Cell Targeting NY-ESO-1 Vaccine, in Patients with Malignant Melanoma Pre-Treated with Recombinant CDX-301, a Recombinant Human Flt3 Ligand.

M. Ernstoff, P. Friedlander, A. Pavlick, 2016 .

S-antigen-specific rat T cell lines recognize peptide fragments of S-antigen and mediate experimental autoimmune uveoretinitis and pinealitis.

S. Fling, D. Gregerson, W. F. Obritsch, 1986, Journal of immunology.

A multiplexed assay for quantifying immunomodulatory proteins supports correlative studies in immunotherapy clinical trials

Jeffrey R. Whiteaker, Regine M. Schoenherr, Jacob J. Kennedy, 2023, Frontiers in Oncology.

A phase 1b/2a study of safety and efficacy of NT-I7 in combination with anti-PD-L1 (atezolizumab) in patients with anti-PD-1/PD-L1 naïve or relapsed/refractory (R/R) high-risk skin cancers: The phase 1b report.

J. Sosman, P. Friedlander, P. Funchain, 2022, Journal of Clinical Oncology.

SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art

Pier Federico Gherardini, Marta Luksza, Bernard A. Fox, 2018, Journal of Immunotherapy for Cancer.

Conserved T cell receptor V gene usage by uveitogenic T cells.

S. Fling, E. Heber-Katz, X. Zhang, 1991, Clinical immunology and immunopathology.

A new perspective of S-antigen from immunochemical analysis.

L. Donoso, S. Fling, D. Gregerson, 1990, Current eye research.

Multiple, spatially distinct T cell epitopes within a pathogenic 123 residue cyanogen bromide peptide of bovine retinal s-antigen.

M. Boyce-Jacino, L. Donoso, S. Fling, 1990, Current eye research.

CITN11-02 interim trial results: subcutaneous administration of recombinant human IL-15 (rhIL-15) is associated with expansion of peripheral blood CD56+ NK cells and CD8+ T cells

T. Waldmann, H. Kohrt, H. Wakelee, 2015, Journal of Immunotherapy for Cancer.

Novel Mutants Define Genes Required for the Expression of Human Histocompatibility Leukocyte Antigen DM: Evidence for Loci on Human Chromosome 6p

B. Arp, S. Fling, K. Muczynski, 1997, The Journal of experimental medicine.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, David M. Schauder, 2016, Journal for ImmunoTherapy of Cancer.

Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.

J. Taube, T. Olencki, E. Lipson, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

T antigen–specific CD8+ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinoma

A. Bentzen, S. Hadrup, S. Topalian, 2024, The Journal of clinical investigation.

432 Nemvaleukin alfa, a novel engineered IL-2 cytokine, in combination with the anti-PD-1 antibody pembrolizumab in patients with recurrent/metastatic head and neck squamous cell carcinoma (ION-01 study)

S. Huh, J. Geiger, S. Fling, 2021, Journal for ImmunoTherapy of Cancer.

Identification of an HIV-1 Clade A Envelope That Exhibits Broad Antigenicity and Neutralization Sensitivity and Elicits Antibodies Targeting Three Distinct Epitopes

Sergei L. Kosakovsky Pond, D. Burton, D. Montefiori, 2013, Journal of Virology.