M. Brenner

发表

Notch signaling drives synovial fibroblast identity and arthritis pathology

N. Hacohen, C. Nusbaum, P. Gregersen, 2020, Nature.

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue

Shuqiang Li, N. Hacohen, C. Nusbaum, 2018, Arthritis Research & Therapy.

Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family.

Michael B Brenner, H. Ford, Marcia M. Miller, 2005, Proceedings of the National Academy of Sciences of the United States of America.

MHC Class II Presentation Is Controlled by the Lysosomal Small GTPase, Arl8b

P. Ricciardi-Castagnoli, M. Brenner, Xavier Michelet, 2015, The Journal of Immunology.

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.

T. Thornhill, M. Warman, J. Smolen, 2010, Arthritis and rheumatism.

Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Mycobacterium tuberculosis Infection

M. Brenner, Xavier Michelet, A. Tuli, 2018, The Journal of Immunology.

Mycobacterium tuberculosis Arl 8 b and Determines Cell Death Type in Repair Is Dependent on the Small GTPase Lysosome-Mediated Plasma Membrane

M. Brenner, Xavier Michelet, A. Tuli, 2018 .

Cadherin‐11 contributes to pulmonary fibrosis: potential role in TGF‐β production and epithelial to mesenchymal transition

Minghua Wu, Seo-Hee Cho, D. J. Schneider, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PD-1hi CXCR5- T peripheral helper cells promote B cells responses in lupus via MAF and IL-21.

A. V. Bocharnikov, M. Petri, B. Diamond, 2019, JCI insight.

CD1 antigen presentation: how it works

Michael B. Brenner, M. Brenner, D. C. Barral, 2007, Nature Reviews Immunology.

Saposins utilize two strategies for lipid transfer and CD1 antigen presentation

Ying Sun, G. Besra, R. Grenha, 2012, Proceedings of the National Academy of Sciences.

The Role of Innate Immunity in Autoimmunity

L. Lanier, M. Shlomchik, M. Kronenberg, 2004, The Journal of experimental medicine.

Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections.

M. Simon, N. Letvin, P. Sehgal, 2002, Science.

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin.

D. Rimm, M. Brenner, S. Shaw, 1994, Nature.

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin

D. Rimm, M. Brenner, S. Shaw, 1994, Nature.

Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity

U. V. von Andrian, A. Tavakkoli, L. Lynch, 2017, Immunity.

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

G. Besra, D. Sant'Angelo, P. Brennan, 2014, Nature Immunology.

Regulatory iNKT cells lack PLZF expression and control Treg cell and macrophage homeostasis in adipose tissue

G. Besra, U. V. von Andrian, D. Sant'Angelo, 2014, Nature immunology.

Human autoreactive T cells recognize CD1b and phospholipids

G. Besra, J. Altman, J. Rossjohn, 2015, Proceedings of the National Academy of Sciences.

CD1b Tetramers Bind \(\alpha \beta \) T Cell Receptors to Identify a Mycobacterial Glycolipid-Reactive T Cell Repertoire in Humans

I. Wilson, J. Altman, A. Schiefner, 2011 .

The Journal of Experimental Medicine CORRESPONDENCE

I. Wilson, J. Altman, A. Schiefner, 2005 .

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

J. Katz, I. van Rhijn, D. Moody, 2009, The Journal of experimental medicine.

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

J. Katz, I. van Rhijn, D. Moody, 2009, The Journal of experimental medicine.

Chapter 1 Antigen Presentation by CD1

M. Brenner, S. Garg, Nadia R. Cohen, 2009 .

CD1 and Tuberculosis

M. Brenner, C. Dascher, 2005 .

New insights into pathways for CD1-mediated antigen presentation.

M. Brenner, M. Cernadas, M. Sugita, 2004, Current opinion in immunology.

T cell activation by lipopeptide antigens.

I. Wilson, D. Zajonc, D. Moody, 2005, Science.

CD 1 and Major Histocompatibility Complex II Molecules Follow a Different Course during Dendritic Cell Maturation

P. Peters, N. V. D. Wel, M. Brenner, 2003 .

Evolutionary constraints on CD1 structure: insights from comparative genomic analysis.

M. Brenner, C. Dascher, 2003, Trends in immunology.

CD1-Restricted Microbial Lipid Antigen-Specific Recognition Found in the CD8+ αβ T Cell Pool

E. Grant, S. Porcelli, M. Brenner, 1999, The Journal of Immunology.

CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection

G. Besra, E. Grant, D. Moody, 2000, Nature.

Fine Specificity of TCR Complementarity-Determining Region Residues and Lipid Antigen Hydrophilic Moieties in the Recognition of a CD1-Lipid Complex1

I. Wilson, G. Besra, M. Degano, 2002, The Journal of Immunology.

Fibroblast‐like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin‐11

M. Brenner, Zhizhan Gu, Sook Kyung Chang, 2010, Immunological reviews.

Mixed Effects Association of Single Cells Identifies an Expanded Th1-Skewed Cytotoxic Effector CD4+ T Cell Subset in Rheumatoid Arthritis

S. Raychaudhuri, E. Karlson, M. Weinblatt, 2018 .

Reverse Association of Single Cells to Rheumatoid Arthritis Accounting for Mixed Effects Identifies an Expanded CD27- HLA-DR+ Effector Memory CD4+ T Cell Population

S. Raychaudhuri, E. Karlson, M. Weinblatt, 2017, bioRxiv.

Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity

J. Lieberman, J. Orange, J. Thiery, 2013, Molecular biology of the cell.

Susceptibility of Mice Deficient in CD1D or TAP1 to Infection with Mycobacterium tuberculosis

Chyung-Ru Wang, M. Brenner, C. Dascher, 1999, The Journal of experimental medicine.

T cell receptor‐dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity

M. Krangel, H. Band, M. Roncarolo, 2000, European journal of immunology.

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly.

M. Brenner, F. Hochstenbach, S. Watkins, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The γδT Cell Receptor

J. Strominger, M. Krangel, M. Brenner, 1988 .

Calnexin retains unassembled major histocompatibility complex class I free heavy chains in the endoplasmic reticulum

M. Brenner, S. Rajagopalan, 1994, The Journal of experimental medicine.

Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain

S. Balk, S. Porcelli, M. Brenner, 1993, The Journal of experimental medicine.

Structural Features of the Acyl Chain Determine Self-phospholipid Antigen Recognition by a CD1d-restricted Invariant NKT (iNKT) Cell*

M. Lafleur, D. Moody, C. Costello, 2003, Journal of Biological Chemistry.

Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit

J. Strominger, I. Trowbridge, M. Brenner, 1985, Cell.

CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice

D. Moody, Chyung-Ru Wang, Hak-Jong Choi, 2009, The Journal of experimental medicine.

CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice

D. Moody, Chyung-Ru Wang, Hak-Jong Choi, 2009, The Journal of experimental medicine.

Rifampin Increases Cytokine-Induced Expression of the CD1b Molecule in Human Peripheral Blood Monocytes

L. Tentori, E. Bonmassar, G. Graziani, 1998, Antimicrobial Agents and Chemotherapy.

CD1--a new paradigm for antigen presentation and T cell activation.

P. Peters, E. Grant, D. Moody, 1998, Clinical immunology and immunopathology.

Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine.

L. Tentori, E. Bonmassar, G. Graziani, 1997, Pharmacological research.

Oligoclonality of human intestinal intraepithelial T cells

M. Brenner, A. Bhan, H. Dersimonian, 1992, The Journal of experimental medicine.

Ion permeation mechanism of the potassium channel

G. Besra, E. Grant, D. Moody, 2022 .

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

Nir Hacohen, Kamil Slowikowski, Andrew Filer, 2018, Nature Communications.

Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases

Joyce B. Kang, S. Raychaudhuri, F. Powrie, 2021, bioRxiv.

SLAMF7 engagement super-activates macrophages in acute and chronic inflammation

P. Blazar, J. K. Lange, D. Rao, 2020, bioRxiv.

Disruptive innovation in rheumatology: new networks of global public–private partnerships are needed to take advantage of scientific progress

S. Raychaudhuri, T. Huizinga, L. Klareskog, 2020, Annals of the Rheumatic Diseases.

Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation.

G. Watts, M. Brenner, B. Madarampalli, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Distinct fibroblast subsets drive inflammation and damage in arthritis

S. Raychaudhuri, H. Perlman, D. Fearon, 2019, Nature.

Cadherin-11 Provides Specific Cellular Adhesion between Fibroblast-like Synoviocytes

D. Patel, G. Watts, M. Brenner, 2004, The Journal of experimental medicine.

Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro.

M. Brenner, David M. Lee, H. Kiener, 2006, The American journal of pathology.

T-cell receptor delta-chain can substitute for alpha to form a beta delta heterodimer.

M. Brenner, F. Hochstenbach, 1989, Nature.

T-cell receptor δ-chain can substitute for α to form a βδ heterodimer

M. Brenner, F. Hochstenbach, 1989, Nature.

Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs.

S. Almo, A. Clatworthy, S. Porcelli, 2000, Journal of immunology.

Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation

P. Peters, S. Kent, H. Shams, 2008, Proceedings of the National Academy of Sciences.

Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells.

S. Porcelli, M. Brenner, S. Behar, 1994, Nature.

Immune cell profiling to guide therapeutic decisions in rheumatic diseases

S. Raychaudhuri, D. Rao, M. Brenner, 2015, Nature Reviews Rheumatology.

Intrathymic programming of effector fates in three molecularly distinct {gamma}{delta} T cell subtypes

N. Malhotra, Katelyn E. Sylvia, Joonsoo Kang, 2012 .

Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen.

L. Tentori, E. Bonmassar, G. Graziani, 1998, Life sciences.

Conservation of a CD1 multigene family in the guinea pig.

E. Kawasaki, S. Porcelli, M. Brenner, 1999, Journal of Immunology.

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

David K. Finlay, S. Beyaz, A. Tavakkoli, 2018, Nature Immunology.

Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.

Alexander S. Banks, A. Kohlgruber, L. Lynch, 2017, The Journal of clinical investigation.

Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules

A. Kaser, S. Zeissig, M. Brenner, 2008, European journal of immunology.

RNAi screens of lysosomal trafficking.

M. Brenner, S. Garg, 2015, Methods in cell biology.

CUX1 and IκBζ mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts

S. Raychaudhuri, Kamil Slowikowski, G. Watts, 2019, bioRxiv.

Serum lipids regulate dendritic cell CD1 expression and function

G. Besra, L. Hugendubler, M. Brenner, 2008, Immunology.

The CD1 family of lipid antigen-presenting molecules.

I. Wilson, S. Porcelli, M. Brenner, 1998, Immunology today.

Class II histocompatibility molecules associate with calnexin during assembly in the endoplasmic reticulum.

M. Brenner, S. Rajagopalan, C. Huntoon, 1994, International immunology.

Activation strategies for invariant natural killer T cells

P. Brennan, A. Kohlgruber, M. Brenner, 2016, Immunogenetics.

Recognition of nonpeptide antigens by T cells

Y. Tanaka, B. Bloom, M. Brenner, 1996, Journal of Molecular Medicine.

Influence of Mycobacterium bovis Bacillus Calmette Guérin on In Vitro Induction of CD1 Molecules in Human Adherent Mononuclear Cells

E. Bonmassar, G. Graziani, A. Aquino, 2002, Infection and Immunity.

Influence of Mycobacterium bovisBacillus Calmette Guérin on In Vitro Induction of CD1 Molecules in Human Adherent Mononuclear Cells

E. Bonmassar, G. Graziani, A. Aquino, 2001, Infection and Immunity.

Pathways of CD1 and lipid antigen delivery, trafficking, processing, loading, and presentation.

M. Brenner, D. C. Barral, M. Sugita, 2007, Current topics in microbiology and immunology.

Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin).

M. Brenner, F. Hochstenbach, S. Rajagopalan, 1993, The Journal of biological chemistry.

Antigen presentation by CD1 and MHC-encoded class I-like molecules.

S. Porcelli, M. Brenner, E. Beckman, 1996, Current opinion in immunology.

Membrane anchoring of calnexin facilitates its interaction with its targets.

S. C. Ho, S. Pillai, M. Brenner, 1999, Molecular immunology.

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells

B. Stranger, S. Raychaudhuri, Wei-Min Chen, 2014, PLoS genetics.

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4[superscript +] Effector Memory T Cells

B. Stranger, S. Raychaudhuri, Wei-Min Chen, 2014 .

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells

B. Stranger, S. Raychaudhuri, Wei-Min Chen, 2014, PLoS genetics.

Subcellular localization of mycobacteria in tissues and detection of lipid antigens in organelles using cryo-techniques for light and electron microscopy.

P. Peters, M. Brenner, C. Dascher, 2005, Current opinion in microbiology.

Pillars article: analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med. 1993. 178: 1-16.

S. Balk, S. Porcelli, M. Brenner, 2014, Journal of immunology.

Identification of guinea pig γδ T cells and characterization during pulmonary tuberculosis

M. Brenner, C. Dascher, J. Bukowski, 2004 .

Analysis of T Cell Antigen Receptor ( TCR ) Expression by Human Peripheral Blood C D 4-8-cr T Cells Demonstrates Preferential Use of Several V ~ Genes and an Invariant TCR cr Chain

M. Brenner, C. E. Yockey, Steven PorceUi, 2003 .

Conservation of CD1 Intracellular Trafficking Patterns Between Mammalian Species1

S. Porcelli, D. Clemens, G. Watts, 2002, The Journal of Immunology.

Distinct structural and functional epitopes of the αEβ7 integrin

E. Ebert, D. Mandelbrot, M. Brenner, 1994 .

Clonally expanded Valpha12+ (AV12S1),CD8+ T cells from a patient with rheumatoid arthritis are autoreactive.

J. Lederer, M. Brenner, S. Behar, 1998, Arthritis and rheumatism.

Self-Terminating during the Course of Rapid NKT Cell Responses Are

M. Brenner, C. Dascher, Asako, 2008 .

Rapid NKT Cell Responses Are Self-Terminating during the Course of Microbial Infection1

A. Chiba, M. Brenner, C. Dascher, 2008, The Journal of Immunology.

Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis–Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria

A. Chiba, M. Brenner, S. Behar, 2008, PLoS pathogens.

Diverse TCRs recognize murine CD1.

M. Brenner, S. Behar, C. Roy, 1999, Journal of immunology.

Apolipoprotein-mediated pathways of lipid antigen presentation

F. Sacks, G. Besra, D. Moody, 2005, Nature.

Mycobacterial Lipid Antigens Responses in Guinea Pigs by Immunization Induction of CD 1-Restricted Immune

S. Porcelli, M. Brenner, C. Dascher, 2002 .

Induction of CD1-Restricted Immune Responses in Guinea Pigs by Immunization with Mycobacterial Lipid Antigens1

S. Porcelli, M. Brenner, C. Dascher, 2002, The Journal of Immunology.

Characterization of guinea‐pig group 1 CD1 proteins

S. Porcelli, M. Brenner, C. Dascher, 2002, Immunology.

A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair

J. Ramalho, Lília Espada, V. Hsu, 2016, The Journal of cell biology.

iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy.

Katherine B. LeClair, Alexander S. Banks, D. Drucker, 2016, Cell metabolism.

iNKT Cells Induce FGF 21 f or Thermogenesis and Are Required for Maximal Weight Loss in GLP 1 Therapy Graphical

Katherine B. LeClair, Alexander S. Banks, D. Drucker, 2016 .

Two forms of the T-cell receptor γ protein found on peripheral blood cytotoxic T lymphocytes

J. Seidman, J. Mclean, M. Krangel, 1987, Nature.

Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition.

S. Colgan, J. Madara, M. Brenner, 1994, The Journal of clinical investigation.

Sufficient for the Development of NK T Cells Expression of CD1d2 on Thymocytes Is Not

T. Chun, Chyung-Ru Wang, M. Brenner, 2013 .

Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis.

S. Porcelli, D. McMurray, G. Watts, 2003, International immunology.

Expression of CD1d2 on thymocytes is not sufficient for the development of NK T cells in CD1d1-deficient mice.

T. Chun, M. Brenner, S. Cardell, 1999, Journal of immunology.

CD 1 d 1-Deficient Mice Sufficient for the Development of NK T Cells Expression of CD 1 d 2 on Thymocytes Is Not

T. Chun, Chyung-Ru Wang, M. Brenner, 1999 .

SpeciesTrafficking Patterns Between Mammalian Conservation of CD1 Intracellular

S. Porcelli, G. Watts, M. Brenner, 2022 .

the Guinea Pig Conservation of a CD1 Multigene Family in

James R. Brown, E. Kawasaki, S. Porcelli, 2022 .

University of Birmingham Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface

G. Besra, J. Rossjohn, D. Pellicci, 2017 .

Transnuclear mice reveal Peyer's patch iNKT cells that regulate B‐cell class switching to IgG1

Lestat R. Ali, S. Crowley, Hee-Jin Jeong, 2019, The EMBO journal.

Arthritis critically dependent on innate immune system players.

Ralph Weissleder, Umar Mahmood, Christophe Benoist, 2002, Immunity.

CD1a-, b-, and c-Restricted TCRs Recognize Both Self and Foreign Antigens1

E. Grant, M. Brenner, M. Vincent, 2005, The Journal of Immunology.

Self-recognition of Cd1 by ␥ / ␦ T Cells: Implications for Innate Immunity

P. Peters, O. Majdic, A. Krensky, 2000 .

Lysosomal Localization of Murine CD1d Mediated by AP-3 Is Necessary for NK T Cell Development 1

G. Besra, P. Peters, M. Brenner, 2003, The Journal of Immunology.

Newly identified γδ and βδ T-cell receptors

M. Brenner, F. Hochstenbach, 2004, Journal of Clinical Immunology.

Human T cell receptor gamma delta structure.

J. Mclean, M. Krangel, H. Band, 1989, Advances in experimental medicine and biology.

Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes.

J. Mclean, M. Krangel, H. Band, 1987, Science.

Natural and synthetic non-peptide antigens recognized by human gamma delta T cells.

Y. Tanaka, B. Bloom, E. Nieves, 1995, Nature.

Flexible migration program regulates γδ T-cell involvement in humoral immunity

B. Moser, M. Brenner, K. Willimann, 2003 .

Crucial role of TCR gamma chain junctional region in prenyl pyrophosphate antigen recognition by gamma delta T cells.

H. Band, M. Brenner, J. Bukowski, 1998, Journal of immunology.

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells.

D. Golan, H. Band, Y. Tanaka, 1995, Immunity.

Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors1

Chi‐Huey Wong, G. Besra, M. Brenner, 2006, The Journal of Immunology.

CD4+-T-Cell Effector Functions and Costimulatory Requirements Essential for Surviving Mucosal Infection with Citrobacter rodentium

L. Bry, M. Brenner, M. Brigl, 2006, Infection and Immunity.

Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit.

J. Mclean, M. Krangel, H. Band, 1987, Science.

Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody.

R. Warnke, J. Mclean, J. Strominger, 1987, Journal of immunology.

Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells.

J. Bonifacino, G. Watts, M. Brenner, 2002, Immunity.

The Lysosomal Small Gtpase, Arl8b Mhc Class Ii Presentation Is Controlled By

P. Ricciardi-Castagnoli, M. Brenner, Xavier Michelet, 2022 .

iNKT Cell Cytotoxic Responses Control T-Lymphoma Growth In Vitro and In Vivo

J. Orange, S. Grupp, K. Nichols, 2013, Cancer Immunology Research.

iNKTCellCytotoxicResponsesControlT-LymphomaGrowth In Vitro and In Vivo

J. Orange, S. Grupp, K. Nichols, 2013 .

CytotoxicResponsesControl T-LymphomaGrowth In Vitro and In Vivo

J. Orange, S. Grupp, K. Nichols, 2013 .

iNKTCell CytotoxicResponsesControl T-LymphomaGrowth In Vitro and In Vivo

J. Orange, S. Grupp, K. Nichols, 2013 .

Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor

J. Mclean, J. Strominger, I. Trowbridge, 1984, The Journal of experimental medicine.

Extensive junctional diversity of rearranged human T cell receptor delta genes.

J. Mclean, J. Strominger, M. Krangel, 1988, Science.

Identification of putative human T cell receptor delta complementary DNA clones.

M. Krangel, M. Brenner, S. Hata, 1987, Science.

CD1 Molecules Efficiently Present Antigen in Immature Dendritic Cells and Traffic Independently of MHC Class II During Dendritic Cell Maturation1

P. Peters, M. Brenner, R. Rogers, 2002, The Journal of Immunology.

Dendritic Cell Maturation Independently of MHC Class II During Immature Dendritic Cells and Traffic CD 1 Molecules Efficiently Present Antigen in

P. Peters, N. V. D. Wel, M. Brenner, 2002 .

VLA‐1: a T cell surface antigen which defines a novel late stage of human T cell activation

J. Strominger, D. Mann, M. Brenner, 1985, European journal of immunology.

Discordant expression of CD3 and T-cell receptor beta-chain antigens in T-lineage lymphomas.

R. Warnke, S. Smith, L. Picker, 1987, The American journal of pathology.

Lymphocytes bearing antigen-specific γδ T-cell receptors accumulate in human infectious disease lesions

B. Bloom, C. Pirmez, M. Brenner, 1989, Nature.

Expression of T cell receptor delta chains in benign and malignant T lineage lymphoproliferations.

R. Warnke, L. Picker, S. Michie, 1988, The American journal of pathology.

T-cell receptors of human suppressor cells

M. Krangel, B. Bloom, M. Brenner, 1987, Nature.

Isolation of anti-idiotypic antibodies to T cells using an anti-framework determinant antibody.

H. Maecker, M. Brenner, K. Kitamura, 1987, Journal of immunological methods.

Direct presentation of non-peptide prenyl pyrophosphate antigens to human γδ T cells

Yoshimasa Tanaka, B. Bloom, M. Brenner, 1996 .

Lymphocytes Bearing Either γδ-TCR or αβ-TCR Can Recognize Non-MHC Encoded CD1 Molecules

S. Balk, S. Porcelli, M. Brenner, 1989 .

T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.

J. Mclean, J. Strominger, M. Krangel, 1987, Proceedings of the National Academy of Sciences of the United States of America.

CHARACTERIZATION OF A THIRD FORM OF THE HUMAN T CELL RECEPTOR y/S

J. Seidman, J. Mclean, J. Strominger, 2003 .

A pathway of costimulation that prevents anergy in CD28- T cells: B7- independent costimulation of CD1-restricted T cells

S. Porcelli, M. Brenner, S. Behar, 1995, The Journal of experimental medicine.

Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells.

J. Mclean, J. Strominger, M. Brenner, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Flexible migration program regulates (cid:1)(cid:2) T-cell involvement in humoral immunity

B. Moser, M. Brenner, K. Willimann, 2003 .

Cd1b-Mediated T Cell Recognition of a Glycolipid Antigen Generated from Mycobacterial Lipid and Host Carbohydrate during Infection

G. Besra, E. Grant, D. Moody, 2000, The Journal of experimental medicine.

Murine CD1d-restricted T cell recognition of cellular lipids.

S. Porcelli, M. Brenner, S. Cardell, 2000, Immunity.

Regulation of CD1 Antigen-presenting Complex Stability*

G. Besra, M. Brenner, R. Tatituri, 2010, The Journal of Biological Chemistry.

Assembly and retention of CD1b heavy chains in the endoplasmic reticulum.

S. Porcelli, M. Brenner, M. Sugita, 1997, Journal of immunology.

Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules

A. Kaser, M. Brenner, R. Blumberg, 2007 .

Aquaporin 2 promotes cell migration and epithelial morphogenesis.

J. Norman, Dennis Brown, H. Lu, 2012, Journal of the American Society of Nephrology : JASN.

Cytotoxic T lymphocytes in resistance to tuberculosis.

K. Rock, B. Bloom, S. Porcelli, 1998, Advances in experimental medicine and biology.

The CD1-restricted T-cell response to mycobacteria.

P. Peters, D. Moody, S. Porcelli, 1996, Research in immunology.

Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner

Irah L. King, G. Besra, Michael Tighe, 2011, Nature Immunology.

A novel monoclonal antibody, 1B3.1, binds to a new epitope of the VLA-1 molecule.

L. Chess, D. Cohen, M. Brenner, 1989, Cellular immunology.

Clonal T lymphocyte recognition of the fine structure of the HLA-A2 molecule.

J. Mclean, J. Strominger, M. Brenner, 1985, Journal of immunology.

The transcriptional programs of iNKT cells.

P. Brennan, L. Lynch, M. Brenner, 2015, Seminars in immunology.

IL-6 Production by Pulmonary Dendritic Cells Impedes Th1 Immune Responses 1

M. Brenner, M. Cernadas, I. Dodge, 2003, The Journal of Immunology.

Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes.

J. Smolen, M. Brenner, David M. Lee, 2009, Arthritis and rheumatism.

A predominance of the T cell receptor V gamma 2/V delta 2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition.

J. Mclean, H. Band, M. Brenner, 1991, Journal of immunology.

CD1-mediated (cid:2) / (cid:3) T Cell Maturation of Dendritic Cells

M. Brenner, C. Morita, F. Spada, 2002 .

Evidence for Human CD4+ T Cells in the CD1-Restricted Repertoire: Derivation of Mycobacteria-Reactive T Cells from Leprosy Lesions1

S. Porcelli, M. Brenner, A. Burdick, 2000, The Journal of Immunology.

T cells expressing gamma delta chain receptors in rheumatoid arthritis.

M. Feldmann, F. Brennan, A. Jackson, 1988, Journal of autoimmunity.

The immune cell landscape in kidneys of patients with lupus nephritis

Nir Hacohen, Matthias Kretzler, Kamil Slowikowski, 2019, Nature Immunology.

, an Attaching and Effacing Pathogen Citrobacter rodentium Mucosal Infection with Lymphoid Tissue, for Surviving Acute Antibody, but Not the Gut-Associated Critical Role of T Cell-Dependent Serum

L. Bry, M. Brenner, 2003 .

Immunity to infection

N. Letvin, M. Brenner, 1992, Current Opinion in Immunology.

Plateletpheresis-associated lymphopenia in frequent platelet donors.

D. Neuberg, D. Longo, D. Wesemann, 2019, Blood.

NK T cells provide lipid antigen-specific cognate help for B cells

G. Besra, S. Pillai, M. Brenner, 2008, Proceedings of the National Academy of Sciences.

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

J. Katz, I. van Rhijn, D. Moody, 2009, The Journal of experimental medicine.

T lymphocyte recognition of human group 1 CD1 molecules: implications for innate and acquired immunity.

M. Brenner, M. Sugita, 2000, Seminars in immunology.

CD1c molecules broadly survey the endocytic system.

P. Peters, M. Brenner, R. Rogers, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Separate pathways for antigen presentation by CD1 molecules.

E. V. van Donselaar, P. Peters, E. Donselaar, 1999, Immunity.

Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission.

T. Yamamura, S. Miyake, M. Brenner, 2003, International immunology.

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

N. Hacohen, G. Besra, M. Brenner, 2011, Immunity.

Lesions Mycobacteria-Reactive T Cells from Leprosy CD 1-Restricted Repertoire : Derivation of T Cells in the + Evidence for Human CD 4 Porcelli and

S. Porcelli, M. Brenner, A. Burdick, 2000 .

Discordant Expression ofCD3 and T-Cell Receptor

R. Warnke, S. Smith, L. Picker, 2007 .

Recognition of mycobacterial antigens by gamma delta T cells.

J. Mclean, H. Band, M. Brenner, 1990, Research in immunology.

Characteristics of 27 Human T-Cell Leukemia Cell Lines With/Without T-Cell Receptors of T3-Tiαβ or T3-Tiγδ Complex

K. Kohno, Y. Matsuo, H. Drexler, 1989 .

Flexible migration program regulates gamma delta T-cell involvement in humoral immunity.

B. Moser, M. Brenner, K. Willimann, 2003, Blood.

How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens.

M. Brenner, M. Brigl, 2010, Seminars in immunology.

Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism

C. Blobel, G. Watts, M. Brenner, 2015, Arthritis Research & Therapy.

Rapid and reliable generation of invariant natural killer T‐cell lines in vitro

P. Brennan, A. Chiba, M. Brenner, 2009, Immunology.

MHC class I-like, class II-like and CD1 molecules: distinct roles in immunity.

M. Brenner, E. Beckman, Evan M. Beckman, 1995, Immunology today.

p126 (CDw101), a costimulatory molecule preferentially expressed on mucosal T lymphocytes.

E. Ebert, M. Brenner, E. Mizoguchi, 1996, Journal of immunology.

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

G. Besra, L. Eggeling, J. Rossjohn, 2013, Proceedings of the National Academy of Sciences.

Structural elucidation of diglycosyl diacylglycerol and monoglycosyl diacylglycerol from Streptococcus pneumoniae by multiple-stage linear ion-trap mass spectrometry with electrospray ionization.

F. Hsu, J. Turk, M. Brenner, 2012, Journal of mass spectrometry : JMS.

Innate recognition of cell wall β-glucans drives invariant natural killer T cell responses against fungi.

G. Besra, B. Fuchs, E. Mylonakis, 2011, Cell host & microbe.

In vitro T lymphocyte proliferative response to Yersinia enterocolitica in Reiter's syndrome. Lack of response in other HLA-B27 positive individuals.

M. Brenner, S. Kobayashi, C. Wiesenhutter, 1984, Arthritis and rheumatism.

Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire [published erratum appears in J Exp Med 1991 Nov 1;174(5):following 1286]

H. Band, M. Brenner, H. Dersimonian, 1991, The Journal of experimental medicine.

Mechanisms of Vδ1 γδ T Cell Activation by Microbial Components1

M. Brenner, M. Sugita, H. Das, 2004, The Journal of Immunology.

Identification of Cadherin 11 as a Mediator of Dermal Fibrosis and Possible Role in Systemic Sclerosis

Anuh T. George, M. Mayes, R. Lafyatis, 2014, Arthritis & rheumatology.

γδ T Cells in Leprosy Lesions

M. Brenner, R. Modlin, J. Ohmen, 1991 .

Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies.

G. Besra, M. Brenner, N. Veerapen, 2010, Bioconjugate chemistry.

CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ alpha beta T cell pool.

E. Grant, S. Porcelli, M. Brenner, 1999, Journal of immunology.

Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d

R. Dwek, G. Besra, P. Rudd, 2010, Proceedings of the National Academy of Sciences of the United States of America.

Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system

R. Warnke, L. Picker, J. Strominger, 1989, The Journal of experimental medicine.

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction

G. Besra, P. Azadi, P. Brennan, 2014, Proceedings of the National Academy of Sciences.

Identification of a putative second T-cell receptor

J. Seidman, J. Mclean, J. Strominger, 1986, Nature.

Recognition of cluster of differentiation 1 antigens by human CD4−CD8>− cytolytic T lymphocyte

S. Balk, S. Porcelli, M. Brenner, 1989, Nature.

CD1 antigen presentation and infectious disease.

M. Brenner, C. Dascher, 2003, Contributions to microbiology.

Activation strategies for invariant natural killer T cells

P. Brennan, A. Kohlgruber, M. Brenner, 2016, Immunogenetics.

Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.

J. Seidman, J. Mclean, M. Krangel, 1987, Nature.

Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide

G. Besra, V. Cerundolo, M. Brenner, 2009, Bioorganic & medicinal chemistry letters.

Recognition of mycobacterial antigens by γδ T cells

J. Mclean, M. Brenner, R. Modlin, 1990 .

Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer.

E. Ebert, J. Madara, M. Brenner, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer.

E. Ebert, J. Madara, M. Brenner, 1998, The American journal of physiology.

Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion

M. Brenner, H. Kiener, 2005, Arthritis research & therapy.

Commentary Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion

M. Brenner, H. Kiener, 2005 .

The synovial cadherin (cadherin-11) promotes intercellular motility

M. Brenner, P. G. Allen, David M. Lee, 2007, Arthritis Research & Therapy.

Cadherin-11 regulates synovial fibroblast behavior in health and disease

M. Takeichi, G. Watts, M. Brenner, 2007, Arthritis Research & Therapy.

Tumor necrosis factor polymorphisms in psoriatic arthritis: association with the promoter polymorphism TNF-857 independent of the PSORS1 risk allele

M. Brenner, P. G. Allen, David M. Lee, 2007, Arthritis Research & Therapy.

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

Nir Hacohen, Kamil Slowikowski, Andrew Filer, 2019, Nature Immunology.

Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies

S. Byers, S. Dakshanamurthy, L. Shapiro, 2013, Oncotarget.

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells

G. Besra, J. Rossjohn, F. Hsu, 2015, The Journal of Immunology.

Characterization of polar lipids of Listeria monocytogenes by HCD and low-energy CAD linear ion-trap mass spectrometry with electrospray ionization

F. Hsu, J. Turk, M. Brenner, 2015, Analytical and Bioanalytical Chemistry.

How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease

C. Benoist, D. Mathis, I. Matsumoto, 2002, Nature Immunology.

High Throughput Identification of Non-Coding Functional SNPs via Type IIS Enzyme Restriction

Y. Okada, S. Raychaudhuri, H. Westra, 2018, Nature Genetics.

CD1d-Restricted NKT Cells Express a Chemokine Receptor Profile Indicative of Th1-Type Inflammatory Homing Cells 1

J. Strominger, C. Hess, T. Means, 2003, The Journal of Immunology.

Calnexin: a membrane-bound chaperone of the endoplasmic reticulum.

D. Y. Thomas, J. Bergeron, J. Bergeron, 1994, Trends in biochemical sciences.

Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire

J. Strominger, H. Band, S. Porcelli, 1990, The Journal of experimental medicine.

Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system

R. Mariuzza, M. Brenner, C. Morita, 2009, Springer Seminars in Immunopathology.

Fast, sensitive, and accurate integration of single cell data with Harmony

Fan Zhang, Kamil Slowikowski, Soumya Raychaudhuri, 2018, bioRxiv.

Direct and Regulated Interaction of Integrin αEβ7 with E-Cadherin

Yih-Tai Chen, E. A. Murphy, M. Brenner, 1998, The Journal of cell biology.

CD1-restricted T cell recognition of microbial lipoglycan antigens.

P. Brennan, M. Kronenberg, B. Bloom, 1995, Science.

Recognition of a lipid antigen by GDI-restricted αβ+ T cells

S. Porcelli, M. Brenner, S. Behar, 1994, Nature.

T Cell Activation by Lipopeptide Antigens

I. Wilson, D. Zajonc, D. Moody, 2004, Science.

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection

L. Bry, S. Kent, M. Brenner, 2003, Nature Immunology.

CD1-dependent dendritic cell instruction

E. Grant, M. Brenner, J. Gumperz, 2002, Nature Immunology.

Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining

Takashi Yamamura, Michael B. Brenner, Jenny E. Gumperz, 2002, The Journal of experimental medicine.

Natural and synthetic non-peptide antigens recognized by human γδ T cells

B. Bloom, E. Nieves, M. Brenner, 1995, Nature.

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

H. Band, Y. Tanaka, B. Bloom, 1995, Journal of immunology.

Functionally distinct subsets of human gamma/delta T cells.

H. Spits, M. Brenner, C. Martínez, 1991, European journal of immunology.

Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions

P. Brennan, M. Brenner, M. Brigl, 2013, Nature Reviews Immunology.

Antigen presentation: Mixing oil and water

S. Porcelli, M. Brenner, 1997, Current Biology.

Invariant natural killer T cells recognize lipid self-antigen induced by microbial danger signals

G. Besra, P. Brennan, F. Hsu, 2011, Nature Immunology.

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

M. Brenner, J. Bukowski, C. Morita, 1999 .

Human gamma delta T cells recognize alkylamines derived from microbes, edible plants, and tea: implications for innate immunity.

M. Brenner, J. Bukowski, C. Morita, 1999, Immunity.

Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity.

M. Brenner, S. Garg, Nadia R. Cohen, 2009, Advances in immunology.

Molecular mechanism of lipopeptide presentation by CD1a.

R. Dwek, I. Wilson, D. Zajonc, 2005, Immunity.

CD1: antigen presentation and T cell function.

Michael B Brenner, M. Brenner, Manfred Brigl, 2004, Annual review of immunology.

Conservation of a CD1 multigene family in the guinea pig.

E. Kawasaki, S. Porcelli, M. Brenner, 1999, Journal of immunology.

A family of beta 7 integrins on human mucosal lymphocytes.

M. Brenner, S. Shaw, R. Schwarting, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection

G. Besra, F. Hsu, G. Watts, 2011, The Journal of experimental medicine.

The immune cell landscape in kidneys of lupus nephritis patients

Nir Hacohen, Matthias Kretzler, Chad Nusbaum, 2018, bioRxiv.

Fibroblast pathology in inflammatory diseases.

Kevin Wei, M. Brenner, H. N. Nguyen, 2021, The Journal of clinical investigation.

Distinct fibroblast subsets drive inflammation and damage in arthritis

S. Raychaudhuri, H. Perlman, D. Fearon, 2019, Nature.

HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness

G. Rätsch, S. Raychaudhuri, L. Ivashkiv, 2019, Science Translational Medicine.

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

N. Hacohen, C. Nusbaum, P. Gregersen, 2018, bioRxiv.

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

Shuqiang Li, N. Hacohen, C. Nusbaum, 2018, bioRxiv.

Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells.

J. Madara, M. Brenner, K. Cepek, 1993, Journal of immunology.

Soft matrix is a natural stimulator for cellular invasiveness

Soo Young Lee, D. Tschumperlin, M. Brenner, 2014, Molecular biology of the cell.

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

P. Gregersen, S. Raychaudhuri, T. Esko, 2019, bioRxiv.

The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules.

P. Stewart, M. Kronenberg, S. Porcelli, 1997, Immunity.

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

S. Porcelli, M. Brenner, C. Morita, 1992, Nature.

HBEGF+ macrophages identified in rheumatoid arthritis promote joint tissue invasiveness and are reshaped differentially by medications

G. Rätsch, S. Raychaudhuri, L. Ivashkiv, 2019, bioRxiv.

The transcriptional landscape of αβ T cell differentiation

Charles C. Kim, G. Nolan, D. Koller, 2013, Nature Immunology.

T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines.

M. Brenner, W. Agace, J. Higgins, 2000, Current opinion in cell biology.

The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility.

M. Brenner, P. G. Allen, H. Kiener, 2006, Molecular biology of the cell.

The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism.

E. Parisini, Jia-huai Wang, Jin‐huan Liu, 2007, Journal of molecular biology.

Molecular Basis for Leukocyte Integrin αEβ7 Adhesion to Epithelial (E)-Cadherin

K. Tan, Jia-huai Wang, D. Mandelbrot, 2000, The Journal of experimental medicine.

IQGAP1 and Calmodulin Modulate E-cadherin Function*

D. Sacks, M. Brenner, J. Higgins, 1999, The Journal of Biological Chemistry.

A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

F. Alt, R. DePinho, L. Chess, 1986, Nature.

Critical Role of T Cell-Dependent Serum Antibody, but Not the Gut-Associated Lymphoid Tissue, for Surviving Acute Mucosal Infection with Citrobacter rodentium, an Attaching and Effacing Pathogen 1

L. Bry, M. Brenner, 2004, The Journal of Immunology.

γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis

Amir I. Mina, Alexander S. Banks, T. Shay, 2018, Nature Immunology.

Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis

Kamil Slowikowski, Elizabeth W Karlson, Soumya Raychaudhuri, 2018, Science Translational Medicine.

Autocrine Loop Involving IL‐6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators

Kevin Wei, G. Watts, F. Mizoguchi, 2017, Immunity.

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

Kamil Slowikowski, Andrew Filer, Soumya Raychaudhuri, 2017, Nature.

Nonpeptide ligands for human gamma delta T cells.

Y. Tanaka, B. Bloom, G. De Libero, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Mucosal T Lymphocyte Numbers Are Selectively Reduced in Integrin αE (CD103)-Deficient Mice

D. Beier, E. A. Murphy, M. Schön, 1999, The Journal of Immunology.

Mast Cells: A Cellular Link Between Autoantibodies and Inflammatory Arthritis

C. Benoist, D. Mathis, D. Friend, 2002, Science.

Distinct iNKT Cell Populations Use IFNγ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis.

A. Kohlgruber, L. Lynch, M. Brenner, 2020, Cell metabolism.

Understanding the function of CD1-restricted T cells

M. Brenner, J. Gumperz, M. Vincent, 2003, Nature Immunology.

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

S. Raychaudhuri, Kamil Slowikowski, M. Gutierrez-Arcelus, 2019, Nature Communications.

Differential effects of cytolytic T cell subsets on intracellular infection.

A. Sette, B. Bloom, S. Porcelli, 1997, Science.

A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE network

N. Hacohen, T. Eisenhaure, M. Kretzler, 2018, bioRxiv.

Clonal V alpha 12.1+ T cell expansions in the peripheral blood of rheumatoid arthritis patients

T. Rème, M. Weinblatt, D. Glass, 1993, The Journal of experimental medicine.

Genetic polymorphism directs IL-6 expression in fibroblasts but not selected other cell types

G. Watts, M. Brenner, E. Noss, 2015, Proceedings of the National Academy of Sciences.

Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis

L. Donlin, M. Postow, S. Goodman, 2021, bioRxiv.

Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration.

M. Weisman, V. Go, Qiang Wang, 2017, The American journal of pathology.

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M. Weisman, V. Go, Qiang Wang, 2016 .

Functionally distinct subsets of human γ/δ T cells

C. Martínez-A, H. Spits, M. Brenner, 1991 .

Arl13b regulates endocytic recycling traffic

J. Ramalho, V. Hsu, G. Watts, 2012, Proceedings of the National Academy of Sciences.

Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution.

E. A. Murphy, M. Brenner, S. Shaw, 1994, The Journal of biological chemistry.

Biology of the Human γ T‐Cell Receptor

H. Band, S. Porcelli, M. Brenner, 1991 .

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

J. Grunewald, A. Eklund, M. Brenner, 2006 .

T Cell V‐Gene Usage in Man in Some Normal and Abnormal Situations a

J. Grunewald, A. Eklund, M. Brenner, 1991, Annals of the New York Academy of Sciences.

Cadherin-11 in Synovial Lining Formation and Pathology in Arthritis

M. Takeichi, G. Watts, M. Brenner, 2007, Science.

Post-EMT: Cadherin-11 mediates cancer hijacking fibroblasts

Xin Hu, P. Friedl, P. Khong, 2019, bioRxiv.

Structure of the Vδ domain of a human γδ T-cell antigen receptor

A. Llera, B. A. Fields, M. Lebedeva, 1998, Nature.

Biology of the human gamma delta T-cell receptor.

H. Band, S. Porcelli, M. Brenner, 1991, Immunological reviews.

Modulation of matrix metalloproteinase production by rheumatoid arthritis synovial fibroblasts after cadherin 11 engagement.

G. Watts, M. Brenner, E. Noss, 2011, Arthritis and rheumatism.

Lymphocyte adhesion to epithelia and endothelia mediated by the lymphocyte endothelial-epithelial cell adhesion molecule glycoprotein.

M. Schön, M. Brenner, C. Shieh, 1999, Journal of immunology.

Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4[superscript +] Effector Memory T Cells

B. Stranger, S. Raychaudhuri, Wei-Min Chen, 2014 .

The gamma delta T cell receptor.

J. Strominger, M. Krangel, M. Brenner, 1988, Advances in immunology.

Retention of unassembled components of integral membrane proteins by calnexin.

M. Brenner, Y. Xu, S. Rajagopalan, 1994, Science.

The immune cell landscape in kidneys of patients with lupus nephritis

Paul J. Hoover, Shuqiang Li, N. Hacohen, 2019, Nature Immunology.

Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells.

M. Brenner, C. Dascher, V. Peña-Cruz, 2003, The Journal of investigative dermatology.

Recognition and destruction of virus-infected cells by human gamma delta CTL.

M. Brenner, J. Bukowski, C. Morita, 1994, Journal of immunology.

Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells

Joonsoo Kang, T. Shay, P. Brennan, 2012, Nature Immunology.

Functional genomics of stromal cells in chronic inflammatory diseases

S. Raychaudhuri, Kamil Slowikowski, Kevin Wei, 2018, Current opinion in rheumatology.

Mechanisms of Vdelta1 gammadelta T cell activation by microbial components.

M. Brenner, M. Sugita, H. Das, 2004, Journal of immunology.

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

Yoshimasa Tanaka, D. Golan, H. Band, 1995 .

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

Manolis Kellis, D. Pennington, L. Dyck, 2021, Nature Immunology.

CD1-mediated γ/δ T Cell Maturation of Dendritic Cells

M. Brenner, C. Morita, F. Spada, 2002, The Journal of experimental medicine.

Molecular Recognition of Lipid Antigens by T Cell Receptors

Ian A. Wilson, Michael B. Brenner, Steven A. Porcelli, 1999, The Journal of experimental medicine.

Cytoplasmic Tail-Dependent Localization of CD1b Antigen-Presenting Molecules to MIICs

E. V. van Donselaar, P. Peters, S. Porcelli, 1996, Science.

Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.

Charles C. White, T. Raj, E. Karlson, 2016, Human molecular genetics.

Antigens and Antigen-Presenting Molecules for γδ T Cells

J. Mclean, S. Porcelli, M. Brenner, 1991 .

Pattern of Interaction with Antigen Complexes: Evidence for a Common Molecular Recognition of Human CD1b

S. Almo, A. Clatworthy, S. Porcelli, 2013 .

Molecular Recognition of Human CD1b Antigen Complexes: Evidence for a Common Pattern of Interaction with αβ TCRs1

Gennaro De Libero, Michael B. Brenner, Steven A. Porcelli, 2000, The Journal of Immunology.

Predominant T cell receptor V gene usage in patients with abnormal clones of B cells.

J. Grunewald, M. Brenner, H. Wigzell, 1991, Blood.

Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFNγ in NK cells.

D. Leaf, J. Varon, T. Shay, 2020, The Journal of clinical investigation.

Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders.

P. Schur, C. Benoist, M. Weinblatt, 2003, Arthritis and rheumatism.

Clonal Vctl 2 . 1 + T Cell Expansions in the Peripheral Blood of Rheumatoid Arthritis Patients

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Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes

N. Malhotra, Katelyn E. Sylvia, Joonsoo Kang, 2012, Nature Immunology.

Regulation of Tumor Necrosis Factor Alpha Gene Expression by Mycobacteria Involves the Assembly of a Unique Enhanceosome Dependent on the Coactivator Proteins CBP/p300

Michael B. Brenner, M. Brenner, C. Dascher, 2003, Molecular and Cellular Biology.

CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts

S. Raychaudhuri, Kamil Slowikowski, G. Watts, 2020, Proceedings of the National Academy of Sciences.

Transendothelial chemotaxis of human αβ and γδ T lymphocytes to chemokines

T. Springer, T. Diacovo, M. Brenner, 1998 .

A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling

P. Brennan, B. Croker, M. Brenner, 2020, Cell reports.

Manifestations of Inflammatory Arthritis Are Critically Dependent on LFA-11

C. Ballantyne, M. Brenner, David M. Lee, 2005, The Journal of Immunology.

Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells

Buhm Han, Soumya Raychaudhuri, Philip L De Jager, 2013, Proceedings of the National Academy of Sciences.

Self-Recognition of Cd1 by γ/δ T Cells

E. V. van Donselaar, P. Peters, O. Majdic, 2000, The Journal of Experimental Medicine.

γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis

Amir I. Mina, Alexander S. Banks, T. Shay, 2018, Nature Immunology.

Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal

Christopher V. Barback, S. Raychaudhuri, Wei Wang, 2020, Science Advances.

CD1-specific T cells in microbial immunity.

M. Brenner, J. Gumperz, Jenny E. Gumperz, 2001, Current opinion in immunology.

A study of the specificity of the direct binding between bacteria and HLA antigens.

D. Kono, M. Brenner, D. Yu, 1984, Clinical and experimental immunology.

Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity.

E. V. van Donselaar, P. Peters, O. Majdic, 2000, The Journal of experimental medicine.

Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions.

B. Bloom, C. Pirmez, M. Brenner, 1989, Nature.

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway

G. Besra, A. Galione, P. Tynan, 2016, Wellcome open research.

Molecule Glycoprotein Endothelial-Epithelial Cell Adhesion Endothelia Mediated by the Lymphocyte Lymphocyte Adhesion to Epithelia and Brenner

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Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice.

D. Beier, E. A. Murphy, M. Schön, 1999, Journal of immunology.

Cloning, expression, and crystallization of the Vδ domain of a human γδ T‐cell receptor

B. A. Fields, M. Lebedeva, R. Mariuzza, 1996, Protein science : a publication of the Protein Society.

Cloning, expression, and crystallization of the VS domain of a human y6 T-cell receptor

B. A. Fields, M. Lebedeva, R. Mariuzza, 1996 .

An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide

M. Brenner, M. Sugita, 1994, The Journal of experimental medicine.

The β7 integrins in mucosal homing and retention

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The beta 7 integrins in mucosal homing and retention.

M. Brenner, S. Shaw, 1995, Seminars in immunology.

Interactions of human alpha/beta and gamma/delta T lymphocyte subsets in shear flow with E-selectin and P-selectin

T. Springer, T. Diacovo, M. Brenner, 1996, The Journal of experimental medicine.

Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration

V. Hsu, M. Brenner, Zhizhan Gu, 2011, The Journal of cell biology.

Cadherin-11 regulates fibroblast inflammation

Soo Young Lee, R. Grenha, M. Brenner, 2011, Proceedings of the National Academy of Sciences.

Early Recycling Compartment Trafficking of CD1a Is Essential for Its Intersection and Presentation of Lipid Antigens

G. De Libero, L. Mori, G. Watts, 2009, The Journal of Immunology.

The Role of α and β Chains in Ligand Recognition by β7 Integrins*

K. Tan, Jia-huai Wang, Y. Takada, 2000, The Journal of Biological Chemistry.

Murine M290 integrin expression modulated by mast cell activation.

M. Brenner, L. Ducharme, S. Shaw, 1994, Immunity.

Role of adhesion molecules in synovial inflammation

M. Brenner, S. Agarwal, 2006, Current opinion in rheumatology.

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

S. Raychaudhuri, Kamil Slowikowski, M. Gutierrez-Arcelus, 2019, Nature Communications.

Antigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune system.

R. Mariuzza, M. Brenner, C. Morita, 2000, Springer seminars in immunopathology.

Single Cell Transcriptomics and Flow Cytometry Reveal Disease-associated Fibroblast Subsets in Rheumatoid Arthritis

N. Hacohen, S. Raychaudhuri, Kamil Slowikowski, 2017, bioRxiv.

Antigen for Diverse NKT Cells Identification of a Potent Microbial Lipid

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Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

S. Beyaz, A. Tavakkoli, L. Dyck, 2018, Nature Immunology.

Innate T Cells Govern Adipose Tissue Biology

A. Kohlgruber, M. Brenner, N. LaMarche, 2018, The Journal of Immunology.

Mechanisms of Vδ1 γδ T Cell Activation by Microbial Components.

M. Brenner, M. Sugita, H. Das, 2004, The Journal of Immunology.

CD1 and major histocompatibility complex II molecules follow a different course during dendritic cell maturation.

Gerty Schreibelt, Peter J Peters, Michael B Brenner, 2003, Molecular biology of the cell.

Insights into Immunoregulation and Pathogenesis from a Third World Disease

W. Jacobs, J. Convit, S. Snapper, 1989 .

Crucial Role of TCRγ Chain Junctional Region in Prenyl Pyrophosphate Antigen Recognition by γδ T Cells

H. Band, M. Brenner, J. Bukowski, 1998, The Journal of Immunology.

Th 1-Type Inflammatory Homing Cells Chemokine Receptor Profile Indicative of CD 1 d-Restricted NKT Cells Express a

Brian J. Wilson, C. Hess, A. Luster, 2003 .

TCR usage and functional capabilities of human gamma delta T cells at birth.

H. Band, M. Brenner, C. Morita, 1994, Journal of immunology.

CD1 assembly and the formation of CD1-antigen complexes.

I. Wilson, D. Zajonc, M. Brenner, 2005, Current opinion in immunology.

Cutting Edge: Major CD8 T Cell Response to Live Bacillus Calmette-Guérin Is Mediated by CD1 Molecules1

I. Yano, M. Brenner, Y. Enomoto, 2003, The Journal of Immunology.

Critically Dependent on LFA-1 Manifestations of Inflammatory Arthritis Are

C. Ballantyne, M. Brenner, David M. Lee, 2005 .

Analysis of clones derived from human CD7+CD4-CD8-CD3- thymocytes.

R. Ware, M. Brenner, K. Weinhold, 1991, International immunology.

Newly identified gamma delta and beta delta T-cell receptors.

M. Brenner, F. Hochstenbach, 1990, Journal of Clinical Immunology.

Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.

M. Brenner, David M. Lee, H. Kiener, 2008, Arthritis and rheumatism.

Pathologically distinct fibroblast subsets drive inflammation and tissue damage in arthritis

S. Raychaudhuri, H. Perlman, D. Fearon, 2018, bioRxiv.

The role of alpha and beta chains in ligand recognition by beta 7 integrins.

Y. Takada, A. Irie, M. Brenner, 2000, The Journal of biological chemistry.

Complex Moieties in the Recognition of a CD 1-Lipid Residues and Lipid Antigen Hydrophilic Complementarity-Determining Region Fine Specificity of TCR

I. Wilson, G. Besra, M. Degano, 2002 .

Cadherin-11 mediates synovial lining organization: a new therapeutic target in inflammatory arthritis

M. Brenner, E. Noss, 2007 .

"Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire"

H. Band, M. Brenner, H. Dersimonian, 1991, The Journal of experimental medicine.

CD1a expression defines an interleukin‐12 producing population of human dendritic cells

G. Watts, M. Brenner, M. Cernadas, 2009, Clinical and experimental immunology.

Expression profiling of constitutive mast cells reveals a unique identity within the immune system

A. Regev, C. Benoist, M. Merad, 2016, Nature Immunology.

Expression of a candidate cadherin in T lymphocytes.

D. Rimm, M. Brenner, K. Cepek, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Conservation and divergence in modules of the transcriptional programs of the human and mouse immune systems

Charles C. Kim, D. Koller, A. Regev, 2018, bioRxiv.

Alpha 4/180, a novel form of the integrin alpha 4 subunit.

M. Brenner, M. Hemler, C. Pujades, 1993, The Journal of biological chemistry.

Diverse TCRs recognize murine CD1.

Chyung-Ru Wang, M. Brenner, S. Behar, 1999, Journal of immunology.

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 1; peer review: 2 approved, 2 approved with reservations]

G. Besra, A. Galione, P. Tynan, 2022 .

iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy.

Katherine B. LeClair, Alexander S. Banks, D. Drucker, 2016, Cell metabolism.

Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells

Joonsoo Kang, T. Shay, P. Brennan, 2012, Nature Immunology.

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 2; peer review: 4 approved]

G. Besra, A. Galione, P. Tynan, 2021 .

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway

G. Besra, A. Galione, P. Tynan, 2016 .

Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor

J. Mclean, J. Strominger, I. Trowbridge, 1984, The Journal of experimental medicine.

Fast, sensitive, and accurate integration of single cell data with Harmony

Kamil Slowikowski, Soumya Raychaudhuri, Michael Brenner, 2019, Nature Methods.

Human T cell receptor-gamma and -delta chain pairing analyzed by transfection of a T cell receptor-delta negative mutant cell line.

J. Mclean, M. Krangel, H. Band, 1990, Journal of immunology.

Increased Frequency of T Cell Receptor Va12.1 Expression on CD8 + T Cells : Evidence that Va

H. Band, M. Brenner, H. Dersimonian, 1991 .

Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis

Shuqiang Li, N. Hacohen, C. Nusbaum, 2019, Nature Immunology.

Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor.

A. Llera, B. A. Fields, M. Lebedeva, 1998, Nature.