S. Adam‐Klages

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

J. Paul Robinson, Jonathan A. Rebhahn, Kylie M. Quinn, 2019, European journal of immunology.

Novel splice variants of human IKKε negatively regulate IKKε‐induced IRF3 and NF‐kB activation

D. Kabelitz, H. Fickenscher, S. Adam‐Klages, 2011, European journal of immunology.

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

R. Spang, P. Stadler, A. Rosenwald, 2012, Nature Genetics.

Caspase‐8 and caspase‐7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF‐R1 receptosomes

D. Kabelitz, B. Edelmann, S. Adam‐Klages, 2011, The EMBO journal.

The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK.

S. Adam‐Klages, G. Scherer, M. Paulsen, 2005, Experimental cell research.

TNF Receptor Component of the Signaling Pathways of the for Activated C-Kinase 1 as a Novel Motif-Containing Protein , Identifies Receptor Neutral Sphingomyelinase Activation , a WD Interaction with Factor Associated with

W. Kolanus, D. Adam, S. Adam‐Klages, 2002 .

Interaction with Factor Associated with Neutral Sphingomyelinase Activation, a WD Motif-Containing Protein, Identifies Receptor for Activated C-Kinase 1 as a Novel Component of the Signaling Pathways of the p55 TNF Receptor1

W. Kolanus, D. Adam, S. Adam‐Klages, 2002, The Journal of Immunology.

Caspase Inhibition Blocks Human T Cell Proliferation by Suppressing Appropriate Regulation of IL-2, CD25, and Cell Cycle-Associated Proteins1

D. Kabelitz, N. Reiling, S. Adam‐Klages, 2004, The Journal of Immunology.

Vδ2 T cell deficiency in granulomatosis with polyangiitis (Wegener's granulomatosis).

S. Sebens, D. Kabelitz, S. Adam‐Klages, 2013, Clinical immunology.

Species-specific differences in the usage of several caspase substrates.

S. Adam‐Klages, S. Ussat, Ulf-Eike Werner, 2002, Biochemical and biophysical research communications.

Monitoring Circulating γδ T Cells in Cancer Patients to Optimize γδ T Cell-Based Immunotherapy

S. Sebens, H. Oberg, D. Kabelitz, 2014, Front. Immunol..

Upregulation of p21(WAF1/Cip1) precedes tumor necrosis factor-induced necrosis-like cell death.

D. Kabelitz, S. Adam‐Klages, G. Scherer, 2002, Biochemical and biophysical research communications.

Inositol-trisphosphate reduces alveolar apoptosis and pulmonary edema in neonatal lung injury.

S. Uhlig, S. Adam‐Klages, S. Schütze, 2012, American journal of respiratory cell and molecular biology.

Down-regulation of the cancer/testis antigen 45 (CT45) is associated with altered tumor cell morphology, adhesion and migration

O. Janssen, D. Kabelitz, S. Adam‐Klages, 2013, Cell Communication and Signaling.

The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

Y. Hannun, D. Kabelitz, L. Kolker, 2009, Proceedings of the National Academy of Sciences.

Small vessel vasculitis and relapsing panniculitis in tumour necrosis factor receptor associated periodic syndrome (TRAPS)

F. Moosig, U. Mrowietz, S. Adam‐Klages, 2004, Annals of the rheumatic diseases.

Topical application of phosphatidyl-inositol-3,5-bisphosphate for acute lung injury in neonatal swine

S. Uhlig, S. Adam‐Klages, S. Schütze, 2012, Journal of cellular and molecular medicine.

Modulation of CD4+ T-cell activation by CD95 co-stimulation

O. Janssen, P. Krammer, D. Kabelitz, 2011, Cell Death and Differentiation.

Role of caspases in TNF‐mediated regulation of cPLA2

S. Adam‐Klages, M. Krönke, 2002, FEBS letters.

TLR-induced immunomodulatory cytokine expression by human gingival stem/progenitor cells.

C. Dörfer, M. Mekhemar, S. Adam‐Klages, 2017, Cellular immunology.

TLR expression profile of human gingival margin-derived stem progenitor cells

C. Dörfer, M. Mekhemar, S. Adam‐Klages, 2015, Medicina oral, patologia oral y cirugia bucal.

Anti-HLA-DR-triggered monocytes mediate in vitro T cell anergy.

M. Schiller, H. Lorenz, J. Kalden, 2008, International immunology.

Cycle-Associated Proteins Regulation of IL-2, CD25, and Cell Proliferation by Suppressing Appropriate Caspase Inhibition Blocks Human T Cell

D. Kabelitz, N. Reiling, S. Adam‐Klages, 2004 .

Regulation of IL-2 , CD 25 , and Cell Proliferation by Suppressing Appropriate Caspase Inhibition Blocks Human T Cell

D. Kabelitz, N. Reiling, S. Adam‐Klages, 2004 .

Caspases and proliferation

S. Adam‐Klages, M. Paulsen, Markus Falk, 2005 .

Human NK Cells Require Caspases for Activation‐Induced Proliferation and Cytokine Release but not for Cytotoxicity

D. Kabelitz, S. Adam‐Klages, G. Scherer, 2010, Scandinavian journal of immunology.

Interaction with XIAP prevents full caspase‐3/‐7 activation in proliferating human T lymphocytes

D. Kabelitz, S. Adam‐Klages, Inga Lepenies, 2008, European journal of immunology.

Cleavage of human cytosolic phospholipase A2 by caspase-1 (ICE) and caspase-8 (FLICE).

S. Adam‐Klages, M. Krönke, S. Lüschen, 1998, Biochemical and biophysical research communications.

18:1/18:1-Dioleoyl-phosphatidylglycerol prevents alveolar epithelial apoptosis and profibrotic stimulus in a neonatal piglet model of acute respiratory distress syndrome.

S. Uhlig, S. Adam‐Klages, S. Schütze, 2014, Pulmonary pharmacology & therapeutics.

In vitro comparison of different carrier materials with rat bone marrow MSCs

D. Kabelitz, S. Adam‐Klages, J. Wiltfang, 2013, Clinical Oral Investigations.

Inhibition of p38 mitogen-activated protein kinase reduces TNF-induced activation of NF-kappaB, elicits caspase activity, and enhances cytotoxicity.

S. Adam‐Klages, G. Scherer, H. Ungefroren, 2004, Experimental cell research.

Death receptors and caspases

O. Janssen, D. Kabelitz, D. Adam, 2005, Immunologic research.

Overexpression of Acid Ceramidase Protects from Tumor Necrosis Factor–Induced Cell Death

T. Linke, K. Sandhoff, D. Adam, 2000, The Journal of experimental medicine.

Aurora kinase inhibitor AZD1152 has an additional effect of platinum on a sequential application at the human ovarian cancer cell line SKOV3

C. Schem, A. Caliebe, S. Sebens, 2013, Archives of Gynecology and Obstetrics.

Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor

D. Adam, S. Adam‐Klages, M. Krönke, 1998, Journal of leukocyte biology.

repp86: A human protein associated in the progression of mitosis.

Friedrich Buck, R. Parwaresch, M. Szczepanowski, 2003, Molecular cancer research : MCR.

Involvement of FAN in TNF-induced apoptosis.

O. Cuvillier, S. Caspar-Bauguil, R. Salvayre, 2001, The Journal of clinical investigation.

CD40 Signals Apoptosis through FAN-regulated Activation of the Sphingomyelin-Ceramide Pathway*

J. Jaffrezou, R. Salvayre, S. Adam‐Klages, 1999, The Journal of Biological Chemistry.

FAN, a Novel WD-Repeat Protein, Couples the p55 TNF-Receptor to Neutral Sphingomyelinase

J. Schneider-Mergener, W. Kolanus, D. Adam, 1996, Cell.

Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.

R. Lüllmann-Rauch, N. Frey, D. Adam, 2016, Cardiovascular research.

Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN‐deficient mice

K. Pfeffer, S. Adam‐Klages, M. Krönke, 1999, The EMBO journal.

Human EML4, a novel member of the EMAP family, is essential for microtubule formation.

R. Parwaresch, S. Adam‐Klages, F. Buck, 2006, Experimental cell research.

gammadelta T-cells: basic features and potential role in vasculitis.

H. Oberg, D. Kabelitz, S. Adam‐Klages, 2010, Clinical and experimental rheumatology.

Novel bispecific antibodies increase γδ T-cell cytotoxicity against pancreatic cancer cells.

S. Freitag-Wolf, S. Sebens, H. Oberg, 2014, Cancer research.

poly(I:C) costimulation induces a stronger antiviral chemokine and granzyme B release in human CD4 T cells than CD28 costimulation

T. Meyer, H. Oberg, D. Kabelitz, 2012, Journal of leukocyte biology.

Ki-Mcm6, a New Monoclonal Antibody Specific to Mcm6: Comparison of the Distribution Profile of Mcm6 and the Ki-67 Antigen

R. Parwaresch, H. Wacker, E. Endl, 2001, Laboratory Investigation.

Activation of ERK1/2 and cPLA(2) by the p55 TNF receptor occurs independently of FAN.

W. Schneider-Brachert, D. Adam, S. Adam‐Klages, 2000, Biochemical and biophysical research communications.

A Novel Cytoplasmic Domain of the p55 Tumor Necrosis Factor Receptor Initiates the Neutral Sphingomyelinase Pathway*

D. Adam, S. Adam‐Klages, M. Krönke, 1996, The Journal of Biological Chemistry.

Caspase-mediated inhibition of human cytosolic phospholipase A2 during apoptosis.

S. Adam‐Klages, M. Krönke, S. Lüschen, 1998, Journal of immunology.

Regulation of repp86 stability by human Siah2.

W. Klapper, R. Parwaresch, M. Szczepanowski, 2007, Biochemical and biophysical research communications.

Monitoring and functional characterization of the lymphocytic compartment in pancreatic ductal adenocarcinoma patients.

M. Ebsen, S. Freitag-Wolf, S. Sebens, 2016, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Influence of physical activity on the immune system in breast cancer patients during chemotherapy

W. Jonat, H. Oberg, C. Röcken, 2018, Journal of Cancer Research and Clinical Oncology.

Sensitization to Death Receptor Cytotoxicity by Inhibition of Fas-associated Death Domain Protein (FADD)/Caspase Signaling

D. Kabelitz, S. Adam‐Klages, G. Scherer, 2000, The Journal of Biological Chemistry.

During Apoptosis 2 Cytosolic Phospholipase A Caspase-Mediated Inhibition of Human

S. Adam‐Klages, M. Krönke, S. Ussat, 1998 .

Un rôle pour la protéine FAN (factor associated with neutral sphingomyelinase activation) dans la signalisation de l’apoptose

O. Cuvillier, S. Adam‐Klages, M. Krönke, 2001 .