D. Pei

发表

Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq.

G. Pan, A. Hutchins, Lin Guo, 2019, Molecular cell.

A negative feedback loop of transcription factors that controls stem cell pluripotency and self‐renewal

G. Pan, D. Pei, Jun Li, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts.

Jialiang Liang, Lingwen Zeng, Biliang Zhang, 2010, Cell stem cell.

Vitamin C enhances the generation of mouse and human induced pluripotent stem cells.

H. Redl, D. Cai, Lingwen Zeng, 2010, Cell stem cell.

Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics

J. Chen, Lin Guo, He Liu, 2011, Cell Research.

Hallmarks of pluripotency

G. Daley, R. Jaenisch, P. Park, 2015, Nature.

Esrrb Activates Oct4 Transcription and Sustains Self-renewal and Pluripotency in Embryonic Stem Cells*

Tao Wang, Duanqing Pei, Miguel A. Esteban, 2008, Journal of Biological Chemistry.

Proprotein Convertase Furin Interacts with and Cleaves Pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi Network*

Ping Wang, G. Thomas, D. Pei, 2004, Journal of Biological Chemistry.

SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1

Shuo Lin, Song Li, Liangliang Xu, 2012, Cell Regeneration.

iPS Cells: Mapping the Policy Issues

Patrick L. Taylor, R. Lovell-Badge, Kazuto Kato, 2009, Cell.

A Dominant-negative Form of Mouse SOX2 Induces Trophectoderm Differentiation and Progressive Polyploidy in Mouse Embryonic Stem Cells*

G. Pan, D. Pei, Jun Li, 2007, Journal of Biological Chemistry.

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

Stephen J. Weiss, Duanqing Pei, S. Weiss, 1995, Nature.

CA‐MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch

D. Pei, 1999, FEBS letters.

Activation of membrane-type matrix metalloproteinase 3 zymogen by the proprotein convertase furin in the trans-Golgi network.

T. Kang, D. Pei, H. Nagase, 2002, Cancer research.

Pluripotency without Proliferation

D. Pei, Xiaodong Shu, 2016, Cell.

Vitamin C modulates TET1 function during somatic cell reprogramming

G. Pan, Hongjie Yao, Guo-liang Xu, 2013, Nature Genetics.

Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells

G. Pan, Minghui Gao, Junwei Wang, 2020, Cell discovery.

Sorting Nexin 33 Induces Mammalian Cell Micronucleated Phenotype and Actin Polymerization by Interacting with Wiskott-Aldrich Syndrome Protein*

Juan Zhang, Liangliang Xu, D. Pei, 2009, The Journal of Biological Chemistry.

VHL inactivation induces HEF1 and Aurora kinase A.

P. Maxwell, S. Harten, D. Shukla, 2010, Journal of the American Society of Nephrology : JASN.

miR-204–containing exosomes ameliorate GVHD-associated dry eye disease

D. Pei, Xialin Liu, R. Ju, 2022, Science advances.

Challenges and advances in clinical applications of mesenchymal stromal cells

D. Pei, P. Lai, Xin Du, 2021, Journal of Hematology & Oncology.

BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone

Jing Chen, Jing Liu, Jiekai Chen, 2011, Cell Research.

BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling

Lin Guo, Xiaoshan Wang, Shangtao Cao, 2020, Nature Cell Biology.

EMT and MET as paradigms for cell fate switching.

D. Pei, Jiekai Chen, Qingkai Han, 2012, Journal of molecular cell biology.

Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells

ping wang, Jing Liu, Sheng Ding, 2011, Cell Research.

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

Wei Li, Y. E. Chen, Jifeng Zhang, 2011, Cell Research.

Icaritin, an Exogenous Phytomolecule, Enhances Osteogenesis but Not Angiogenesis—An In Vitro Efficacy Study

Yixiang Wang, Xin-luan Wang, D. Pei, 2012, PloS one.

Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

Ruilin Sun, Shanping Jiang, Binghui Chen, 2020, National science review.

Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

H. Shan, Z. Wu, Z. Li, 2020, medRxiv.

Treating COVID-19 with Chloroquine

Duanqing Pei, Hong Shan, Mingxing Huang, 2020, Journal of molecular cell biology.

Sequential EMT-MET induces neuronal conversion through Sox2

D. Pei, Hui Zheng, Yuan Li, 2017, Cell Discovery.

Stem cell aging in adult progeria

W. Chan, D. Pei, H. Cheung, 2015, Cell Regeneration.

Editorial Amniotic Stem Cells: Potential in Regenerative Medicine

T. Nikaido, M. Bani‐Yaghoub, D. Pei, 2012 .

The Battle between TET Proteins and DNA Methylation for the Right Cell.

Dongwei Li, D. Pei, Jiekai Chen, 2018, Trends in cell biology.

IL-6 trans-signaling promotes the expansion and anti-tumor activity of CAR T cells

Yangqiu Li, Suna Wang, D. Pei, 2020, Leukemia.

Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells

Yangqiu Li, Yi-long Wu, Suna Wang, 2017, Journal of Hematology & Oncology.

In vitro culture and directed osteogenic differentiation of human pluripotent stem cells on peptides-decorated two-dimensional microenvironment.

B. Xie, D. Pei, Yi Deng, 2015, ACS applied materials & interfaces.

The efficacy and safety of CAR-T cell therapy in patients with refractory ALL and concomitant HBV infection

D. Pei, P. Li, P. Lai, 2020, Leukemia.

Identification and Characterization of the Fifth Membrane-type Matrix Metalloproteinase MT5-MMP*

D. Pei, 1999, The Journal of Biological Chemistry.

A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo

Shuo Lin, Bin Wu, Song Li, 2011, Cell Research.

Sorting Nexin 10 Induces Giant Vacuoles in Mammalian Cells*

D. Pei, M. He, Baoming Qin, 2006, Journal of Biological Chemistry.

Total synthesis of cyclic tetrapeptide FR235222, a potent immunosuppressant that inhibits mammalian histone deacetylases.

D. Pei, D. Ma, B. Zou, 2005, Organic letters.

CD215+ Myeloid Cells Respond to Interleukin 15 Stimulation and Promote Tumor Progression

Yangqiu Li, Suna Wang, W. Ye, 2017, Front. Immunol..

Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

Liu Wang, Qi Zhou, Xiao Han, 2018, Cancer communications.

Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells

G. Pan, Y. Liu, P. Liu, 2013, Cell Regeneration.

Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer

Suna Wang, Yang Li, Zhenfeng Zhang, 2019, Journal of Hematology & Oncology.

DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells

Yangqiu Li, Suna Wang, Peng Li, 2018, Oncoimmunology.

The Art of Reprogramming for Regenerative Medicine

J. Kuang, D. Pei, Tao Huang, 2022, Frontiers in Cell and Developmental Biology.

Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo

Huanxing Su, Haitao Wang, Lin Guo, 2015, Cell Regeneration.

Application of iPS Cells in Dental Bioengineering and Beyond

P. Liu, D. Pei, Jinglei Cai, 2014, Stem Cell Reviews and Reports.

BMP4 drives primed to naïve transition through PGC-like state

Shangtao Cao, He Liu, Jing Liu, 2022, Nature Communications.

Where cell fate conversions meet Chinese philosophy

G. Pan, A. Hutchins, D. Pei, 2014, Cell Research.

The E3 Ligase MIB1 Promotes Proteasomal Degradation of NRF2 and Sensitizes Lung Cancer Cells to Ferroptosis

D. Pei, Xiaofei Zhang, Xiaodong Shu, 2021, Molecular Cancer Research.

Hypoproliferative human neural progenitor cell xenografts survived extendedly in the brain of immunocompetent rats

G. Pan, Di Zhang, Haitao Wang, 2021, Stem cell research & therapy.

Hypoproliferative human NPC xenografts survived extendedly in the brain of immunocompetent rats

G. Pan, Di Zhang, Haitao Wang, 2020 .

Expression of matrix metalloproteinase‐2 and ‐9 and their inhibitors, tissue inhibitor of metalloproteinase‐1 and ‐2, in primary cultures of human prostatic stromal and epithelial cells * †

Michael J. Wilson, R. Sellers, D. Peehl, 2002, Journal of cellular physiology.

Melanoma Chondroitin Sulfate Proteoglycan Regulates Matrix Metalloproteinase-dependent Human Melanoma Invasion into Type I Collagen*

M. Herlyn, T. Kang, M. Simpson, 2001, The Journal of Biological Chemistry.

Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma

Suna Wang, P. Liu, Xiaofeng Jiang, 2017, Front. Immunol..

Establishment of peripheral blood mononuclear cell-derived humanized lung cancer mouse models for studying efficacy of PD-L1/PD-1 targeted immunotherapy

Suna Wang, Peng Li, Xiaofang Sun, 2018, mAbs.

Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells

G. Pan, Zhibin Wang, Cizhong Jiang, 2015, Scientific Reports.

Functional characterization of MT3‐MMP in transfected MDCK cells: progelatinase A activation and tubulogenesis in 3‐D collagen lattice

D. Pei, A. Jiang, Wangrong Yang, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Serum metalloproteinase leukolysin (MMP‐25/MT‐6): a potential metabolic marker for atopy‐associated inflammation

D. Pei, M. Blumenthal, M. Miller, 2010, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

In their words

Ling-An Wu, Li Gong, Liping Wei, 2008 .

Rejuvenation of &bgr; cells by epigenetic editing

D. Pei, Tao Wang, 2018, The Journal of clinical investigation.

H3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition

Shangtao Cao, J. Kuang, Dongwei Li, 2022, Cell & bioscience.

Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage

D. Pei, 1999, Cell Research.

An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish

Shuo Lin, Song Li, Liangliang Xu, 2012, Hepatology.

Evaluation of CML TKI Induced Cardiovascular Toxicity and Development of Potential Rescue Strategies in a Zebrafish Model

D. Pei, Heying Li, Xiaodong Shu, 2021, Frontiers in Pharmacology.

Membrane type-1 matrix metalloproteinase promotes human melanoma invasion and growth.

J. Iida, D. Pei, J. McCarthy, 2004, The Journal of investigative dermatology.

SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding.

D. Pei, Yongli Shan, Xiaodong Shu, 2017, Structure.

SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells

D. Pei, Dajiang Qin, Xiaodong Shu, 2013, Cell Regeneration.

Expression, purification and charaterization of recombinant mouse MT5‐MMP protein products

Jianxun Lei, D. Pei, J. Yi, 1999, FEBS letters.

Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation

H. Schöler, Xinwen Chen, J. Kuang, 2020, National science review.

C3aR costimulation enhances the antitumor efficacy of CAR-T cell therapy through Th17 expansion and memory T cell induction

D. Pei, P. Lai, Yulian Wang, 2022, Journal of Hematology & Oncology.

Distinct Roles of Catalytic and Pexin-like Domains in Membrane-type Matrix Metalloproteinase (MMP)-mediated Pro-MMP-2 Activation and Collagenolysis*

D. Pei, A. Jiang, Aixiang Jiang, 2003, Journal of Biological Chemistry.

Overexpression of matrix metalloproteinases leads to lethality in transgenic Xenopus laevis: Implications for tissue‐dependent functions of matrix metalloproteinases during late embryonic development

Yunbo Shi, D. Pei, Qing Li, 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended Phox Homology (PX) Domain Critical for Inhibition of SNX10-induced Vacuolation*

Bin Wu, D. Pei, Tingting Xu, 2013, The Journal of Biological Chemistry.

Zfyve9a regulates the proliferation of hepatic cells during zebrafish embryogenesis.

D. Pei, Nian Liu, Xiaodong Shu, 2013, The International journal of developmental biology.

anti-psychotic drug, enhances the generation of induced pluripotent stem cells.

Sheng Ding, Jing Liu, D. Pei, 2011 .

Mutations of nuclear localization signals in mNANOG generate dominant negative mutants

Juan Zhang, D. Pei, Xiaofei Zhang, 2009 .

Aromatic Residues in the C-terminal Domain 2 Are Required for Nanog to Mediate LIF-independent Self-renewal of Mouse Embryonic Stem Cells*

Zhe Wang, D. Pei, X. Chi, 2008, Journal of Biological Chemistry.

Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium

F. Hou, Shangtao Cao, D. Pei, 2022, Cell & Bioscience.

Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1.

Michael J. Wilson, D. Pei, A. Jiang, 2004, Journal of andrology.

Co-recycling of MT1-MMP and MT3-MMP through the Trans-Golgi Network

J. Keski‐Oja, D. Pei, D. Ma, 2004, Journal of Biological Chemistry.

Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3.

S. Weiss, D. Pei, G. Majmudar, 1994, The Journal of biological chemistry.

Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and transition to a decoupling state.

Y. Zhang, Xiaomin Ma, Wei Zhang, 2022, Cell reports.

Reprogramming in suspension

D. Pei, Jiekai Chen, 2012, Nature Methods.

Direct activation of pro-matrix metalloproteinase-2 by leukolysin/membrane-type 6 matrix metalloproteinase/matrix metalloproteinase 25 at the asn(109)-Tyr bond.

D. Pei, J. Nie, 2003, Cancer research.

Oligomerization through Hemopexin and Cytoplasmic Domains Regulates the Activity and Turnover of Membrane-type 1 Matrix Metalloproteinase*

J. Keski‐Oja, K. Lehti, D. Pei, 2002, The Journal of Biological Chemistry.

Complete Restoration of Cell Surface Activity of Transmembrane-truncated MT1-MMP by a Glycosylphosphatidylinositol Anchor

J. Pei, D. Pei, M. Blumenthal, 2007, Journal of Biological Chemistry.

Mint-3 Regulates the Retrieval of the Internalized Membrane-type Matrix Metalloproteinase, MT5-MMP, to the Plasma Membrane by Binding to Its Carboxyl End Motif EWV*

Ping Wang, D. Pei, Xing Wang, 2004, Journal of Biological Chemistry.

Generation of tooth–periodontium complex structures using high-odontogenic potential dental epithelium derived from mouse embryonic stem cells

D. Pei, Jinglei Cai, Shicheng Wei, 2017, Stem Cell Research & Therapy.

Modeling of hemophilia A using patient-specific induced pluripotent stem cells derived from urine cells.

G. Pan, Juan Du, P. Liu, 2014, Life sciences.

Reprogramming of mouse and human somatic cells by high‐performance engineered factors

Jialei Hu, Jing Liu, D. Pei, 2011, EMBO reports.

Why it is important to study human–monkey embryonic chimeras in a dish

Elias T. Zambidis, J. I. Izpisúa Belmonte, Nam Pho, 2022, Nature Methods.

Valproic acid‐induced hepatotoxicity in alpers syndrome is associated with mitochondrial permeability transition pore opening‐dependent apoptotic sensitivity in an induced pluripotent stem cell model

D. Pei, Liang Yang, Xingguo Liu, 2015, Hepatology.

Valproic Acid-induced Hepatotoxicity in Alpers Syndrome is Associated with mPTP Opening Dependent Apoptotic Sensitivity in an iPSC Model

D. Pei, Liang Yang, Xingguo Liu, 2015 .

Differentiation of secreted and membrane-type matrix metalloproteinase activities based on substitutions and interruptions of triple-helical sequences.

K. Brew, C. Overall, G. Fields, 2007, Biochemistry.

The Roles of Substrate Thermal Stability and P2 and P1′ Subsite Identity on Matrix Metalloproteinase Triple-helical Peptidase Activity and Collagen Specificity*

K. Brew, C. Overall, G. Fields, 2006, Journal of Biological Chemistry.

The Hemopexin Domain of Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) Is Not Required for Its Activation of proMMP2 on Cell Surface but Is Essential for MT1-MMP-mediated Invasion in Three-dimensional Type I Collagen*

Ping Wang, D. Pei, J. Nie, 2004, Journal of Biological Chemistry.

Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle.

J. Wan, Huanxing Su, Wutian Wu, 2013, Stem cell research.

Three-dimensional molecular architecture of mouse organogenesis

Xiaoping Zhou, D. Pei, Jiekai Chen, 2022, bioRxiv.

Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset

Danhua Jiang, Yi-jia Lin, J. Kuang, 2022, Science advances.

Regeneration of the human segmentation clock in somitoids in vitro

Shangtao Cao, Fang Wu, J. Kuang, 2022, The EMBO journal.

Single Cell Sequencing Reveals Early PGC-like Intermediates During Mouse Primed to Naïve Transition

Shangtao Cao, He Liu, Jing Liu, 2021 .

Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells

Yangqiu Li, W. Ye, P. Liu, 2015, Journal of Hematology & Oncology.

Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3

Jufang Huang, T. Egan, D. Pei, 2016, Traffic.

An efficient and tunable route to AG7088, a rhinovirus protease inhibitor

D. Pei, Q. Lei, D. Ma, 2004, Tetrahedron Letters.

Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA

D. Pei, Liang Yang, Haite Tang, 2015, Cellular and Molecular Life Sciences.

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva

G. Pan, C. Mummery, P. ten Dijke, 2015, Stem cell reports.

Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors

D. Pei, Xiaodong Shu, Yihan Zhang, 2022, Cell Death & Disease.

Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids

J. Chan, H. Chu, D. Pei, 2022, Signal Transduction and Targeted Therapy.

What controls organ regeneration

D. Pei, 2017 .

Generation of tooth-like structures from integration-free human urine induced pluripotent stem cells

G. Pan, Y. Liu, P. Liu, 2013, Cell Regeneration.

Differentiation of mouse embryonic stem cells into dental epithelial-like cells induced by ameloblasts serum-free conditioned medium.

Yan Jin, Yunshan Guo, Juan Tang, 2010, Biochemical and biophysical research communications.

MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition*

Maikun Teng, Liwen Niu, Xiangpeng Guo, 2011, The Journal of Biological Chemistry.

Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits

Jiang Peng, James F. Griffith, Ling Qin, 2015, Biomaterials.

Mesenchymal–epithelial transition in development and reprogramming

J. Thiery, D. Pei, Xiaodong Shu, 2019, Nature Cell Biology.

Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

K. Yuen, J. Ziebuhr, R. Hilgenfeld, 2005, PLoS Biology.

Assembly of indole-2-carboxylic acid esters through a ligand-free copper-catalysed cascade process.

D. Pei, Zhengqiu Li, Q. Cai, 2009, Chemical communications.

Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reactions.

D. Pei, Zhengqiu Li, Q. Cai, 2010, Organic letters.

Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants.

Honglin Li, Shaomeng Wang, Shiliang Li, 2013, Angewandte Chemie.

Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant.

Ke Ding, Zhang Zhang, Yong Xu, 2012, Journal of medicinal chemistry.

Total synthesis of cyclic tetrapeptide FR235222, a potent immunosuppressant that inhibits mammalian histone deacetylases.

D. Pei, D. Ma, B. Zou, 2005, Organic letters.

Genomic instability in laminopathy-based premature aging

David J. Chen, K. Cheah, C. López-Otín, 2005, Nature Medicine.

Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine

T. Nikaido, A. Gruslin, M. Hengstschläger, 2012, Stem cells international.

Amniotic Stem Cells: Potential in Regenerative Medicine

T. Nikaido, M. Hengstschläger, M. Bani‐Yaghoub, 2012, Stem cells international.

Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin.

A. Schambach, D. Zychlinski, D. Pei, 2011, Human molecular genetics.

Direct generation of ES-like cells from unmodified mouse embryonic fibroblasts by Oct4/Sox2/Myc/Klf4

D. Pei, Wen Li, Dajiang Qin, 2007, Cell Research.

Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime

Zhe Zhang, N. Lemoine, Lirong Zhang, 2020, Frontiers in Immunology.

Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition

G. Pan, Minghui Gao, Junwei Wang, 2019, The Journal of Biological Chemistry.

Urine as a source of stem cells.

H. Tse, W. Tian, J. Grillari, 2013, Advances in biochemical engineering/biotechnology.

Generation of human induced pluripotent stem cells from urine samples

H. Tse, J. Grillari, D. Pei, 2012, Nature Protocols.

Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments

Yangqiu Li, Suna Wang, W. Ye, 2015, Journal of Hematology & Oncology.

PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells

Yangqiu Li, Suna Wang, Peng Li, 2017, Oncoimmunology.

Generation of induced pluripotent stem cells from urine.

H. Tse, H. Redl, J. Grillari, 2011, Journal of the American Society of Nephrology : JASN.

Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel

D. Pei, Yuanyue Shan, Mingfeng Zhang, 2023, bioRxiv.

Transcription Activator-like Effector Nuclease (TALEN)-mediated Gene Correction in Integration-free β-Thalassemia Induced Pluripotent Stem Cells*

Hui Zhang, Guangjin Pan, Duanqing Pei, 2013, The Journal of Biological Chemistry.

Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in β-Thalassemia Induced Pluripotent Stem Cells (iPSCs)*

G. Pan, Nansheng Chen, D. Pei, 2015, The Journal of Biological Chemistry.

Effects of cholic acid modified glucosamine on chondrogenic differentiation

X. Zhu, Yingjun Wang, D. Pei, 2016 .

Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch

D. Pei, Yunqian Guo, Hui Zheng, 2016, Scientific Reports.

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells

Yangqiu Li, G. Qing, Donghai Wu, 2015, Haematologica.

Cyclin-dependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State*

M. Washburn, L. Florens, T. Xie, 2015, The Journal of Biological Chemistry.

The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters

H. Tse, A. Hutchins, Haitao Wu, 2014, Cell Research.

Resolution of Reprogramming Transition States by Single Cell RNA-Sequencing

G. Pan, A. Hutchins, Lin Guo, 2017, bioRxiv.

Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.

W. Liu, F. Tang, Boqiang Hu, 2014, Cell stem cell.

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

Jieying Zhu, Lin Guo, Jiekai Chen, 2012, Nature Genetics.

The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

G. Pan, Lingwen Zeng, D. Pei, 2011, Cell stem cell.

GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways

Yangqiu Li, Suna Wang, W. Ye, 2016, Oncotarget.

Ribosomal RNA Gene Transcription Mediated by the Master Genome Regulator Protein CCCTC-binding Factor (CTCF) Is Negatively Regulated by the Condensin Complex*

G. Pan, Cizhong Jiang, Kaimeng Huang, 2013, The Journal of Biological Chemistry.

The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity

Siyuan Lin, Guan-Zheng Luo, Mingwei Gao, 2021, Nature.

RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions.

Chunhui Hou, A. Hutchins, Shaorong Gao, 2017, Cell stem cell.

RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions.

Chunhui Hou, A. Hutchins, Shaorong Gao, 2017, Cell stem cell.

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

G. Pan, Hongjie Yao, Xiaoshan Wang, 2017, Nature Communications.

Long-term self-renewal of human pluripotent stem cells on peptide-decorated poly(OEGMA-co-HEMA) brushes under fully defined conditions.

X. Zhao, Z. Li, Y. Deng, 2013, Acta biomaterialia.

Generation of integration-free neural progenitor cells from cells in human urine

G. Pan, Huanxing Su, Wutian Wu, 2013, Nature Methods.

Title Generation of integration-free neural progenitor cells from cellsin human urine

G. Pan, Huanxing Su, Wutian Wu, 2013 .

SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.

Yangming Wang, Lin Guo, J. Kuang, 2020, Cell reports.

Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function.

Xiaozhong Peng, A. Hutchins, B. Qiang, 2017, Cell reports.

Stem-like Cancer Cells Are Inducible by Increasing Genomic Instability in Cancer Cells

Quentin Liu, Y. Zeng, T. Kang, 2009, The Journal of Biological Chemistry.

Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming

H. Tse, W. Chan, Hong Song, 2015, Nature Cell Biology.

Efficient induction of neural progenitor cells from human ESC/iPSCs on Type I Collagen

Bo Feng, Haitao Wang, Dongwei Li, 2021, Science China Life Sciences.

Metabolic switch and epithelial–mesenchymal transition cooperate to regulate pluripotency

D. Pei, Hui Zheng, Yuan Li, 2020, The EMBO journal.

Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming

H. Schöler, D. Pei, Xingguo Liu, 2020, The EMBO journal.

Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming.

D. Pei, Liang Yang, Haite Tang, 2018, Cell metabolism.

Chromatin Accessibility Dynamics during iPSC Reprogramming.

A. Hutchins, Lin Guo, Xiaoshan Wang, 2017, Cell stem cell.

Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming.

Yong Li, Qi Long, Linpeng Li, 2016, Cell metabolism.

Transcriptional pause release is a rate-limiting step for somatic cell reprogramming.

Jun Wang, A. Schambach, Minghui He, 2014, Cell stem cell.

Transitions between epithelial and mesenchymal states during cell fate conversions

Duanqing Pei, D. Pei, Hui Zheng, 2014, Protein & Cell.

The mesenchymal-to-epithelial transition in somatic cell reprogramming.

D. Pei, Q. Zhuang, Ting Zhou, 2012, Current opinion in genetics & development.

Therapeutic developments in matrix metalloproteinase inhibition

P. Shah, T. Rajavashisth, D. Pei, 2002 .

The oncogene c-Jun impedes somatic cell reprogramming

G. Pan, A. Hutchins, Kaimeng Huang, 2015, Nature Cell Biology.

Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells

G. Pan, Junwei Wang, Di Zhang, 2020, Cell Discovery.

Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune response

G. Pan, Jie Liu, D. Pei, 2014, Science China Life Sciences.

Low Immunogenicity of Neural Progenitor Cells Differentiated from Induced Pluripotent Stem Cells Derived from Less Immunogenic Somatic Cells

G. Pan, P. Liu, D. Pei, 2013, PloS one.

JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells

G. Pan, D. Pei, Chuman Wu, 2020, Nature Communications.

Cancer: pathological nuclear reprogramming?

Xin Lu, D. Pei, C. Goding, 2014, Nature Reviews Cancer.

Chinese a Nti鄄 Cancer a Ssociation

J. Yun, Y. Zeng, T. Kang, 2022 .

Generation of Human Induced Pluripotent Stem Cells from Umbilical Cord Matrix and Amniotic Membrane Mesenchymal Cells*

Huanxing Su, Wutian Wu, K. So, 2010, The Journal of Biological Chemistry.

Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency

Shangtao Cao, Jing Liu, D. Pei, 2021, Cell Regeneration.

Chromatin accessibility dynamics during cell fate reprogramming

P. Zhu, Dongwei Li, D. Pei, 2021, EMBO reports.

Fast and Efficient Mouse Pluripotency Reprogramming Using a Chemically-Defined Medium

D. Pei, Jiekai Chen, Jie Wang, 2022, Methods and protocols.

AP-1 activity is a major barrier of human somatic cell reprogramming

Yuting Liu, Lin Guo, He Liu, 2021, Cellular and Molecular Life Sciences.

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4.

G. Pan, P. Zhu, Yuting Liu, 2019, Cell reports.

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency.

G. Pan, Xiaoshan Wang, Shangtao Cao, 2018, Cell stem cell.

Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage

Yuting Liu, Lin Guo, Xiaoshan Wang, 2017, The Journal of Biological Chemistry.

Srebp‐1 Interacts with c‐Myc to Enhance Somatic Cell Reprogramming

D. Pei, Xingguo Liu, Keshi Chen, 2016, Stem cells.

Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo

Huanxing Su, Haitao Wang, Lin Guo, 2015, Cell Regeneration.

Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming, and long non-coding RNAs

A. Hutchins, D. Pei, 2015, Science bulletin.

Failure to replicate the STAP cell phenomenon

Peter J. Park, George Q. Daley, Marius Wernig, 2015, Nature.

The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming.

Duanqing Pei, D. Pei, Xiaodong Shu, 2014, Current opinion in genetics & development.

The homeobox transcription factor MSX2 partially mediates the effects of bone morphogenetic protein 4 (BMP4) on somatic cell reprogramming

X. Yang, D. Pei, Hui Zheng, 2018, The Journal of Biological Chemistry.

MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin

Wenjing Guo, Shangtao Cao, Jing Liu, 2022, Stem Cell Reviews and Reports.

JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

G. Pan, S. Akira, Ji-fan Hu, 2020, Nature Communications.

Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade

G. Pan, D. Pei, D. Ye, 2020, Nature Metabolism.

Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming

D. Pei, Hui Zheng, Dajiang Qin, 2019, Cell Discovery.

Mesenchymal–epithelial transition in development and reprogramming

J. Thiery, D. Pei, Xiaodong Shu, 2019, Nature Cell Biology.

Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction

D. Pei, Xingguo Liu, Keshi Chen, 2017, Cell Death & Disease.

Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells

Xiaoshan Wang, D. Pei, Jiekai Chen, 2017, The Journal of Biological Chemistry.

A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes

G. Pan, A. Hutchins, D. Pei, 2017, Nature Communications.

Gadd45a is a heterochromatin relaxer that enhances iPS cell generation

G. Pan, H. Schöler, D. Pei, 2016, EMBO reports.

TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells

Wenhao Huang, Guangjin Pan, Duanqing Pei, 2016, Scientific Reports.

Generating a Non-Integrating Human Induced Pluripotent Stem Cell Bank from Urine-Derived Cells

Hui Zhang, Rongping Luo, Jundi Hou, 2013, PloS one.

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming

G. Pan, Jing Liu, D. Pei, 2013, Nature Cell Biology.

Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells.

G. Pan, Huanxing Su, Wutian Wu, 2013, Stem cell research.

Class IIa Histone Deacetylases and Myocyte Enhancer Factor 2 Proteins Regulate the Mesenchymal-to-Epithelial Transition of Somatic Cell Reprogramming*

Haitao Wu, D. Pei, Longqi Liu, 2013, The Journal of Biological Chemistry.

Order from chaos: single cell reprogramming in two phases.

G. Pan, D. Pei, 2012, Cell stem cell.

Stem cell science on the rise in China.

Qi Zhou, D. Sipp, T. Cheng, 2012, Cell stem cell.

The mighty mice prove pluripotency for iPSCs.

D. Pei, 2010, Journal of molecular cell biology.

Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases

H. Tse, D. Pei, M. Esteban, 2010, Thrombosis and Haemostasis.

MicroRNAs in somatic cell reprogramming.

D. Pei, Q. Zhuang, Baoming Qin, 2013, Current opinion in cell biology.

The N-terminal domain is a transcriptional activation domain required for Nanog to maintain ES cell self-renewal

G. Pan, J Zhang, D. Pei, 2009 .

The C-terminal Pentapeptide of Nanog Tryptophan Repeat Domain Interacts with Nac1 and Regulates Stem Cell Proliferation but Not Pluripotency*

D. Pei, Yunqian Guo, Zhe Wang, 2009, The Journal of Biological Chemistry.

Regulation of Pluripotency and Reprogramming by Transcription Factors*

D. Pei, 2009, Journal of Biological Chemistry.

Proteins in DNA methylation and their role in neural stem cell proliferation and differentiation

H. Loh, D. Pei, Hui Zheng, 2021, Cell Regeneration.

Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals.

G. Pan, D. Pei, Baoming Qin, 2004, Experimental cell research.

Verified the effectiveness of AsCpf1 system in a variety of vertebrate species

Shilong Chu, Hong Song, D. Pei, 2018, bioRxiv.

Identification of New Transcription Factors that Can Promote Pluripotent Reprogramming

P. Zhu, Dongwei Li, D. Pei, 2021, Stem Cell Reviews and Reports.

Somatic cell reprogramming for regenerative medicine: SCNT vs. iPS cells

G. Pan, Hongjie Yao, D. Pei, 2012, BioEssays : news and reviews in molecular, cellular and developmental biology.

Porcine induced pluripotent stem cells may bridge the gap between mouse and human iPS

D. Pei, L. Lai, Jianyong Xu, 2010, IUBMB life.

Induced pluripotent stem cell technology in regenerative medicine and biology.

Miguel A Esteban, Hung-Fat Tse, Duanqing Pei, 2010, Advances in biochemical engineering/biotechnology.

SS18 regulates pluripotent-somatic transition through phase separation

Wenjing Guo, Shangtao Cao, J. Kuang, 2021, Nature Communications.

The nuclear factor CECR2 promotes somatic cell reprogramming by reorganizing the chromatin structure

P. Zhu, J. Kuang, Jing Liu, 2020, The Journal of biological chemistry.

Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes.

A. Schambach, B. Menten, D. Zychlinski, 2012, Human molecular genetics.

Induced Pluripotent Stem Cells Can Be Used to Model the Genomic Imprinting Disorder Prader-Willi Syndrome*

D. Pei, L. Lai, Wen Li, 2010, The Journal of Biological Chemistry.

Towards an Optimized Culture Medium for the Generation of Mouse Induced Pluripotent Stem Cells*

Jing Liu, Jiekai Chen, Wenzhi He, 2010, The Journal of Biological Chemistry.

Research Highlight The Mighty Mice Prove Pluripotency for iPSCs

D. Pei, 2010 .

Generation of Induced Pluripotent Stem Cell Lines from Tibetan Miniature Pig*

D. Pei, Jiekai Chen, L. Lai, 2009, The Journal of Biological Chemistry.

Induced pluripotent stem cell (iPS) technology: promises and challenges

D. Pei, Yi Gan, Dajiang Qin, 2009 .

Mouse Meningiocytes Express Sox2 and Yield High Efficiency of Chimeras after Nuclear Reprogramming with Exogenous Factors*

Shaorong Gao, Lingwen Zeng, D. Pei, 2008, Journal of Biological Chemistry.

The magic continues for the iPS strategy

D. Pei, 2008, Cell Research.

Epigenetic Landmarks During Somatic Reprogramming

D. Pei, Jiekai Chen, 2016, IUBMB life.

Membrane type-matrix metalloproteinases (MT-MMP).

C. López-Otín, S. Zucker, D. Pei, 2003, Current topics in developmental biology.

Single cell atlas of developing mouse dental germs reveals populations of CD24+ and Plac8+ odontogenic cells.

Zhonghan Li, Xiaoming Chen, Hong-ying Huang, 2022, Science bulletin.

A new diaryl urea compound, D181, induces cell cycle arrest in the G1 and M phases by targeting receptor tyrosine kinases and the microtubule skeleton

Honglin Li, Hualiang Jiang, D. Pei, 2012, Investigational New Drugs.

Generation of RAG 1- and 2-deficient rabbits by embryo microinjection of TALENs

Peng Li, D. Pei, L. Lai, 2013, Cell Research.

Matrix metalloproteinases target protease-activated receptors on the tumor cell surface.

D. Pei, 2005, Cancer cell.

Increased aggressiveness of human prostate PC-3 tumor cells expressing cell surface localized membrane type-1 matrix metalloproteinase (MT1-MMP).

Michael J. Wilson, J. Slaton, D. Pei, 2009, Journal of andrology.

Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells

Yangqiu Li, Suna Wang, Xiaofang Sun, 2021, Oncogene.

Species-specific rewiring of definitive endoderm developmental gene activation via endogenous retroviruses through TET1-mediated demethylation.

A. Hutchins, Zhongqi Liufu, Lin Guo, 2022, Cell reports.

A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer

Zhe Zhang, P. Liu, C. Chelala, 2019, Clinical Cancer Research.

Cancer stem cells: advances in biology and clinical translation-a Keystone Symposia report.

I. Weissman, R. White, X. Wang, 2021, Annals of the New York Academy of Sciences.

Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity

Jiucun Wang, Weichen Zhou, L. Jin, 2014, BMC Genomics.

Establishment of porcine and human expanded potential stem cells

Lia S. Campos, Fengtang Yang, S. Teichmann, 2019, Nature Cell Biology.

The magic of four: induction of pluripotent stem cells from somatic cells by Oct4, Sox2, Myc and Klf4

D. Pei, H. Qi, 2007, Cell Research.

JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells

G. Pan, D. Pei, Chuman Wu, 2020, Nature Communications.

Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade

Yi Wu, G. Pan, D. Pei, 2020, Nature Metabolism.

Insight into the maintenance of odontogenic potential in mouse dental mesenchymal cells based on transcriptomic analysis

P. Liu, Yuming Zhao, L. Ge, 2016, PeerJ.

Establishment of porcine and human expanded potential stem cells

Lia S. Campos, Fengtang Yang, S. Teichmann, 2019, Nature Cell Biology.

Human induced-T-to-natural killer cells have potent anti-tumour activities

Yangqiu Li, T. Graf, W. Feng, 2022, Biomarker research.

Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia

Yangqiu Li, Suna Wang, W. Ye, 2017, Oncotarget.

Subcellular Distribution and Cytokine- and Chemokine-regulated Secretion of Leukolysin/MT6-MMP/MMP-25 in Neutrophils*

C. Overall, T. Kang, A. Guo, 2001, The Journal of Biological Chemistry.

Regulation of the Pluripotency Marker Rex-1 by Nanog and Sox2*

G. Pan, D. Pei, Yunqian Guo, 2006, Journal of Biological Chemistry.

Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells. VOLUME 283 (2008) PAGES 4480-4489

D. Pei, X. Chi, Tianhua Ma, 2009, Journal of Biological Chemistry.

Transitions between epithelial and mesenchymal states during cell fate conversions

D. Pei, Hui Zheng, Xiang Li, 2014, Protein & Cell.

A reciprocal antagonism between miR‐376c and TGF‐β signaling regulates neural differentiation of human pluripotent stem cells

G. Pan, D. Pei, Zhenghui Su, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized

Yangqiu Li, Suna Wang, W. Ye, 2016, Journal of Hematology & Oncology.

MAP2K6 remodels chromatin and facilitates reprogramming by activating Gatad2b-phosphorylation dependent heterochromatin loosening

Jing Liu, D. Pei, Jiekai Chen, 2021, Cell Death & Differentiation.

Low-dose AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice with subtle antibody response

Bo Feng, Chi-kong Li, D. Pei, 2022, Nature Communications.

Stem cell aging in adult progeria

W. Chan, D. Pei, H. Cheung, 2015, Cell Regeneration.

Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis

Qi Wang, D. Pei, Tingting Xu, 2014, Proteins.

PX domain and CD domain play different roles in localization and vacuolation of Sorting Nexin 10

Bin Wu, D. Pei, Baoming Qin, 2009 .

Toll-like receptor 2 costimulation potentiates the antitumor efficacy of CAR T Cells

D. Pei, P. Lai, J. Weng, 2018, Leukemia.

Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

Xiaoshan Wang, D. Pei, Heying Li, 2018, Nature Communications.

Piglets cloned from induced pluripotent stem cells

Huanming Yang, Zhenzhen Yang, Jing Li, 2012, Cell Research.

Differential Inhibition of Membrane Type 3 (MT3)-Matrix Metalloproteinase (MMP) and MT1-MMP by Tissue Inhibitor of Metalloproteinase (TIMP)-2 and TIMP-3 Regulates Pro-MMP-2 Activation*

M. Bernardo, R. Fridman, M. Kashiwagi, 2004, Journal of Biological Chemistry.

Atovaquone derivatives as potent cytotoxic and apoptosis inducing agents.

Lei Duan, F. Zhou, D. Pei, 2009, Bioorganic & medicinal chemistry letters.

Deubiquitylating Nanog: novel role of USP21 in embryonic stem cell maintenance

D. Pei, 2017, Signal Transduction and Targeted Therapy.

SNX17 Recruits USP9X to Antagonize MIB1-Mediated Ubiquitination and Degradation of PCM1 during Serum-Starvation-Induced Ciliogenesis

D. Pei, Heying Li, Wenguang Yin, 2019, Cells.

GATA2−/− human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment

G. Pan, Juan Du, Xiaofang Sun, 2015, Cell Regeneration.

The Stem Cell Pluripotency Factor NANOG Activates Transcription with Two Unusually Potent Subdomains at Its C Terminus*

G. Pan, D. Pei, 2005, Journal of Biological Chemistry.

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

G. Pan, Hongjie Yao, Xiaoshan Wang, 2017, Nature Communications.

Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway.

Qiang He, Ke Ding, Zhang Zhang, 2010, ACS medicinal chemistry letters.

Single-cell RNA sequencing reveals the developmental program underlying proximal–distal patterning of the human lung at the embryonic stage

Qina He, Shangtao Cao, He Liu, 2023, Cell Research.

Vitamin C improves the quality of somatic cell reprogramming

D. Pei, M. Esteban, 2012, Nature Genetics.

Remission for Loss of Odontogenic Potential in a New Micromilieu In Vitro

A. Hutchins, P. Liu, L. Ge, 2016, PloS one.

Human Embryo Editing: Opportunities and Importance of Transnational Cooperation.

R. Lovell-Badge, R. Jaenisch, J. Rossant, 2017, Cell stem cell.

Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C

C. Siu, H. Tse, D. Pei, 2011, Aging.

Cysteine Array Matrix Metalloproteinase (CA-MMP)/MMP-23 Is a Type II Transmembrane Matrix Metalloproteinase Regulated by a Single Cleavage for Both Secretion and Activation*

D. Pei, Tiebang Kang, Huaxiong Qi, 2000, The Journal of Biological Chemistry.

Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming.

D. Pei, Liang Yang, Haite Tang, 2019, Cell metabolism.

Naloxone regulates the differentiation of neural stem cells via a receptor‐independent pathway

H. Loh, P. Law, D. Pei, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Models of global gene expression define major domains of cell type and tissue identity

A. Hutchins, Yong Wang, Xiaoshan Wang, 2017, Nucleic acids research.

Identification of a Nuclear Localization Signal in OCT4 and Generation of a Dominant Negative Mutant by Its Ablation*

Guangjin Pan, Nan Liu, Duanqing Pei, 2004, Journal of Biological Chemistry.

BMI1 enables interspecies chimerism with human pluripotent stem cells

G. Pan, Shilong Chu, Hong Song, 2018, Nature Communications.

Shedding of Membrane Type Matrix Metalloproteinase 5 by a Furin-type Convertase

D. Pei, Xing Wang, 2001, The Journal of Biological Chemistry.

A Novel CCK Receptor GPR173 Mediates Potentiation of GABAergic Inhibition

Y. Chan, D. Pei, Ge Zhang, 2023, The Journal of Neuroscience.

Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis

Stephen J. Weiss, Duanqing Pei, S. Weiss, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of a novel cell penetrating peptide derived from human Oct4

B. Nordén, Vaibhav Jadhav, N. Borth, 2014, Cell Regeneration.

Intracellular Activation of Human Adamalysin 19/Disintegrin and Metalloproteinase 19 by Furin Occurs via One of the Two Consecutive Recognition Sites*

T. Kang, D. Pei, Q. Sang, 2002, The Journal of Biological Chemistry.

Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

K. Yuen, J. Ziebuhr, R. Hilgenfeld, 2005, PLoS biology.

Mechanism of physical force induced human slack channel desensitization

D. Pei, Yuanyue Shan, Mingfeng Zhang, 2023, bioRxiv.

The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity

Ying Lin, Siyuan Lin, Guan-Zheng Luo, 2021, Nature.

A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity

D. Pei, C. Cox, Yuanyue Shan, 2023, Nature communications.

Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells.

G. Pan, N. Wong, T. Zeng, 2015, Gastroenterology.

Fluidic and air-stable supported lipid bilayer and cell-mimicking microarrays.

G. Veglia, Yini Wang, A. Guo, 2008, Journal of the American Chemical Society.

UBE2O and USP7 co‐regulate RECQL4 ubiquitinylation and homologous recombination‐mediated DNA repair

M. Vermeulen, D. Pei, Dajiang Qin, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling

Lin Guo, Xiaoshan Wang, Shangtao Cao, 2020, Nature Cell Biology.

Mouse embryonic stem cells resist c-Jun induced differentiation when in suspension

Dongwei Li, Jing Liu, D. Pei, 2018, Cell regeneration.

2008: year of the rat for stem cell research

D. Pei, 2009, Cell Research.

Generation of tooth–periodontium complex structures using high-odontogenic potential dental epithelium derived from mouse embryonic stem cells

D. Pei, Jinglei Cai, Shicheng Wei, 2017, Stem Cell Research & Therapy.

The NuRD complex cooperates with SALL4 to orchestrate reprogramming

J. Kuang, He Liu, Jing Liu, 2023, Nature communications.

Simple and versatile synthetic polydopamine-based surface supports reprogramming of human somatic cells and long-term self-renewal of human pluripotent stem cells under defined conditions.

G. Pan, D. Pei, Shicheng Wei, 2016, Biomaterials.

Regulation of MT1‐MMP activity by β‐catenin in MDCK non‐cancer and HT1080 cancer cells

Ping Liu, J. Pei, D. Pei, 2010, Journal of cellular physiology.

SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells

D. Pei, Dajiang Qin, Xiaodong Shu, 2013, Cell Regeneration.

BMI1 enables interspecies chimerism with human pluripotent stem cells

G. Pan, Shilong Chu, Hong Song, 2018, Nature Communications.

Looking Back: Epigenomics.

D. Pei, 2017, Cell stem cell.

Cryo-EM structures of kalium channelrhodopsins KCRs

D. Pei, Yuanyue Shan, Liping Zhao, 2022, bioRxiv.

c-JUN is a barrier in hESC to cardiomyocyte transition

A. Hutchins, J. Kuang, Dongwei Li, 2023, Life Science Alliance.

Establishing extended pluripotent stem cells from human urine cells

Shilong Chu, D. Pei, Guangming Wu, 2023, Cell & Bioscience.

ZBTB7A regulates primed‐to‐naïve transition of pluripotent stem cells via recognition of the PNT‐associated sequence by zinc fingers 1–2 and recognition of γ‐globin −200 gene element by zinc fingers 1–4

Yunyu Shi, Jing Liu, D. Pei, 2023, The FEBS journal.

Epigenetic reshaping through damage: promoting cell fate transition by BrdU and IdU incorporation

Jing Liu, D. Pei, Chen Li, 2023, bioRxiv.

Identification and characterization of a new splicing variant of vascular endothelial growth factor: VEGF183.

Jianxun Lei, D. Pei, A. Jiang, 1998, Biochimica et biophysica acta.

Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune response

G. Pan, D. Pei, Jinglei Cai, 2014, Science China Life Sciences.

Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in β-Thalassemia Induced Pluripotent Stem Cells (iPSCs)*

G. Pan, Nansheng Chen, D. Pei, 2015, The Journal of Biological Chemistry.

Modeling of hemophilia A using patient-specific induced pluripotent stem cells derived from urine cells.

G. Pan, Juan Du, D. Pei, 2014, Life sciences.

Vitamin C enhances the generation of mouse and human induced pluripotent stem cells.

H. Redl, D. Cai, Lingwen Zeng, 2010, Cell stem cell.

Mitochondrial fusion provides an ‘initial metabolic complementation’ controlled by mtDNA

D. Pei, Liang Yang, Haite Tang, 2015, Cellular and Molecular Life Sciences.

An Efficient Synthesis of ABT-263, a Novel Inhibitor of Antiapoptotic Bcl-2 Proteins

D. Pei, K. Ding, Hu-Shan Zhang, 2008 .

Three-dimensional molecular architecture of mouse organogenesis

Xiaoping Zhou, D. Pei, Jiekai Chen, 2023, Nature communications.

Rapid inactivation of alpha-1-proteinase inhibitor by neutrophil specific leukolysin/membrane-type matrix metalloproteinase 6.

D. Pei, J. Nie, 2004, Experimental Cell Research.

Chapter 169 – Membrane-type Matrix Metalloproteinase 6

D. Pei, 2013 .

Expression and purification of membrane-type MMPs.

D. Pei, J. Nie, 2010, Methods in molecular biology.

Membrane-type Matrix Metalloproteinase 6

D. Pei, 2004 .