I. Kirby

发表

A novel antibody targeting ICOS increases intratumoural cytotoxic to regulatory T cell ratio and induces tumour regression

Hanif Ali, R. Sainson, A. Thotakura, 2019 .

High resolution structures of HIV-1 RT from four RT-inhibitor complexes.

D. Stuart, R. Esnouf, E. Garman, 1996 .

Adenovirus Type 9 Fiber Knob Binds to the Coxsackie B Virus-Adenovirus Receptor (CAR) with Lower Affinity than Fiber Knobs of Other CAR-Binding Adenovirus Serotypes

B. Sutton, I. Kovesdi, T. Wickham, 2001, Journal of Virology.

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

S. Furlan, Jeffrey S. Miller, B. Blazar, 2017, Science Translational Medicine.

Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor

N. Hooper, Sue E. Hutchinson, I. Kirby, 2009, The Biochemical journal.

The Human HLA-A*0201 Allele, Expressed in Hamster Cells, Is Not a High-Affinity Receptor for Adenovirus Type 5 Fiber

T. Elliott, I. Kirby, G. Santis, 1999, Journal of Virology.

Adenovirus type 5 uptake by lung adenocarcinoma cells in culture correlates with Ad5 fibre binding is mediated by αvβ1 integrin and can be modulated by changes in β1 integrin function

I. Kirby, I. Hart, G. Santis, 2001, Journal of Gene Medicine.

High resolution structures of HIV-1 RT from four RT–inhibitor complexes

Yvonne Jones, Elspeth Garman, Graham Darby, 1995, Nature Structural Biology.

Identification of Contact Residues and Definition of the CAR-Binding Site of Adenovirus Type 5 Fiber Protein

Andrew J. Beavil, Brian J. Sutton, A. Beavil, 2000, Journal of Virology.

An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression

Hanif Ali, R. Sainson, A. Thotakura, 2020, Cancer Immunology Research.

Molecular determinants of adenovirus serotype 5 fibre binding to its cellular receptor CAR.

J. Bergelson, M. Mehtali, R. Finberg, 1999, The Journal of general virology.

Anti-pd-l1 et cytokines il-2

I. Kirby, S. D. Gillies, Tom Gallagher, 2017 .

Analysis of the interaction between RGD-expressing adenovirus type 5 fiber knob domains and alphavbeta3 integrin reveals distinct binding profiles and intracellular trafficking.

Maddy Parsons, James Hunt, Andrew Beavil, 2006, The Journal of general virology.

Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR

A. Beavil, B. Sutton, I. Kovesdi, 1999, Journal of Virology.

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery

Anneliese O. Speak, A. Speak, A. Bradley, 2014, Nature Biotechnology.

3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes.

D. Stuart, R. Esnouf, A. Hopkins, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Crystals of HIV-1 reverse transcriptase diffracting to 2.2 A resolution.

R. Esnouf, D. Stammers, J. Ren, 1994, Journal of molecular biology.

Adenovirus type-5 entry and disassembly followed in living cells by FRET, fluorescence anisotropy, and FLIM.

M. Martin-Fernandez, D. Clarke, M. Tobin, 2004, Biophysical journal.

Anticorps anti-pd-l1

S. Arkinstall, M. Kosmač, J. Campbell, 2017 .