S. Quaratino

发表

A novel antibody targeting ICOS increases intratumoural cytotoxic to regulatory T cell ratio and induces tumour regression

Hanif Ali, R. Sainson, A. Thotakura, 2019 .

Celiac Disease: a model autoimmune disease with gene therapy applications

L. Maiuri, S. Quaratino, M. Londei, 2003, Gene Therapy.

Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease

V. Raia, L. Maiuri, S. Auricchio, 2003, The Lancet.

Split activity of interleukin‐10 on antigen capture and antigen presentation by human dendritic cells: Definition of a maturative step

D. Douek, S. Quaratino, M. Londei, 1997, European journal of immunology.

Inhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosis

V. Raia, L. Maiuri, S. Auricchio, 2005, Thorax.

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

A. Ballabio, E. Masliah, N. Brunetti‐Pierri, 2010, Nature Cell Biology.

Lysosomal accumulation of gliadin p31–43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARγ downregulation in intestinal epithelial cells and coeliac mucosa

V. Villella, L. Maiuri, M. Pettoello‐Mantovani, 2009, Gut.

Prognosis of stage II and III colon cancer treated with adjuvant 5-fl uorouracil or FOLFIRI in relation to microsatellite status : results of the PETACC-3 trial †

C. Bokemeyer, J. Tabernero, B. Melichar, 2014 .

Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice

D. Kioussis, L. Maiuri, S. Quaratino, 2004, Nature Medicine.

Anti tumour necrosis‐α therapy increases the number of FOXP3+ regulatory T cells in children affected by Crohn’s disease

S. Quaratino, M. Londei, I. Ricciardelli, 2008, Immunology.

Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fc epsilon receptor by a recombinant human autoantibody Fab converted to IgE.

S. Quaratino, M. Londei, B. Rapoport, 1996, Journal of immunological methods.

Interleukin 15 mediates epithelial changes in celiac disease.

L. Maiuri, S. Auricchio, S. Quaratino, 2000, Gastroenterology.

Fully competent dendritic cells as inducers of T cell anergy in autoimmunity

S. Quaratino, M. Londei, LP Duddy, 2001, Proceedings of the National Academy of Sciences of the United States of America.

miR-19–Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer

G. Thomas, A. Mirnezami, R. Mitter, 2015, Molecular Cancer Research.

Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial.

C. Bokemeyer, E. Van Cutsem, J. Tabernero, 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

Non-small Cell Lung Cancer, NSCLC

S. Quaratino, U. Forssmann, Jens-Peter Marschner, 2014 .

A search for the holy grail: non-toxic gluten for celiac patients.

L. Maiuri, S. Quaratino, M. Londei, 2005, Gastroenterology.

Gliadin as a stimulator of innate responses in celiac disease.

L. Maiuri, S. Quaratino, M. Londei, 2005, Molecular immunology.

Innate and adaptive immune responses to the major Parietaria allergen Par j 1 in healthy subjects.

C. Di Sano, P. Colombo, S. Quaratino, 2013, Immunobiology.

FAS engagement drives apoptosis of enterocytes of coeliac patients

V. Raia, L. Maiuri, S. Auricchio, 2001, Gut.

Blockage of T-cell costimulation inhibits T-cell action in celiac disease.

L. Maiuri, S. Auricchio, S. Quaratino, 1998, Gastroenterology.

Activation-induced cell death of self-reactive regulatory T cells drives autoimmunity

S. Quaratino, O. Cexus, E. Badami, 2019, Proceedings of the National Academy of Sciences.

Phenotypic and Functional Heterogeneity of Double Negative (CD4-CD8-) αβ TcR+ T Cell Clones

S. Quaratino, M. Londei, J. Murison, 1991 .

Expression of the identical V beta gene in human T-cell clones does not confer the same pattern of responsiveness to bacterial enterotoxins.

S. Quaratino, M. Londei, A. Verhoef, 1993, Immunology.

ICOS-Positive Regulatory T Cells in Hepatocellular Carcinoma: The Perspective from Digital Pathology Analysis

Chih-Hung Hsu, R. Sainson, A. Cheng, 2022, Oncology.

P. Travers, S. Quaratino, M. Londei, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Unexpected role of surface transglutaminase type II in celiac disease.

V. Raia, L. Maiuri, S. Quaratino, 2005, Gastroenterology.

Fully competent dendritic cells as inducers of T cell anergy in autoimmunity.

S. Quaratino, M. Londei, L. Duddy, 2000 .

Human CD4- CD8- alpha beta+ T cells express a functional T cell receptor and can be activated by superantigens.

S. Quaratino, M. Londei, A. Verhoef, 1991, Journal of immunology.

Human Autoantibodies Modulate the T Cell Epitope Repertoire but Fail to Unmask a Pathogenic Cryptic Epitope1

S. Quaratino, M. Londei, B. Rapoport, 2005, The Journal of Immunology.

This information is current as Pathogenic Cryptic Epitope Epitope Repertoire but Fail to Unmask a Human Autoantibodies Modulate the T Cell

S. Quaratino, M. Londei, B. Rapoport, 2004 .

SUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation1

V. Villella, V. Raia, L. Maiuri, 2009, The Journal of Immunology.

Definition of unique traits of human CD4− CD8−αβ T cells

S. Quaratino, M. Londei, A. Verhoef, 1993 .

Down-Regulation γ via PPAR Modulates Inflammation in Cystic Fibrosis Tissue Transglutaminase Activation

V. Villella, L. Maiuri, S. Quaratino, 2008 .

A first-in-human study of KY1044, a fully human anti-ICOS IgG1 antibody as monotherapy and in combination with atezolizumab in patients with selected advanced malignancies.

R. Sainson, A. Thotakura, Simon J. Henderson, 2019, Journal of Clinical Oncology.

This information is current as Inflammation Link between Oxidative Stress and SUMOylation of Tissue Transglutaminase as

V. Villella, V. Raia, L. Maiuri, 2009 .

Models of autoimmune thyroiditis

S. Quaratino, 2004 .

Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases define the migratory characteristics of human monocyte‐derived dendritic cells

S. Quaratino, M. Londei, M. Tortorella, 2002, Immunology.

Prospects for combining targeted and conventional cancer therapy with immunotherapy

Jeffrey A. Engelman, G. Dranoff, J. Engelman, 2017, Nature Reviews Cancer.

T-cell activation by treatment of cancer patients with EMD 521873 (Selectikine), an IL-2/anti-DNA fusion protein

R. Stupp, D. Speiser, C. Sessa, 2013, Journal of Translational Medicine.

Thrombotic Microangiopathy of the Miscellaneous Secondary Type Responding to Plasma Exchange in a Liver Transplant Recipient

S. Quaratino, U. Valente, M. Valbonesi, 1988, The International journal of artificial organs.

Plasma Exchange for the Management of Cyclosporin A-Induced Hypertriglyceridemia

S. Quaratino, D. Occhini, M. Valbonesi, 1988, The International journal of artificial organs.

New Approaches in Immunotherapy for the Treatment of Lung Cancer.

S. Quaratino, U. Forssmann, Jens-Peter Marschner, 2014, Current topics in microbiology and immunology.

IL-15 drives the specific migration of CD94+ and TCR-γδ+ intraepithelial lymphocytes in organ cultures of treated celiac patients

L. Maiuri, S. Auricchio, S. Quaratino, 2001, American Journal of Gastroenterology.

Human self-reactive T cell clones expressing identical T cell receptor beta chains differ in their ability to recognize a cryptic self-epitope

M. Feldmann, O. Acuto, S. Quaratino, 1996, The Journal of experimental medicine.

Basic Mechanisms in Autoimmunity

S. Quaratino, 2007 .

An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression

Hanif Ali, R. Sainson, A. Thotakura, 2020, Cancer Immunology Research.

OX40L Inhibition Suppresses KLH‐driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof‐of‐Pharmacology for KY1005

M. Moerland, S. Quaratino, J. Burggraaf, 2022, Clinical pharmacology and therapeutics.

High incidence of spontaneous autoimmune thyroiditis in immunocompetent self-reactive human T cell receptor transgenic mice.

L. Maiuri, S. Quaratino, E. Badami, 2005, Journal of autoimmunity.

ProteinImmune Responses to Prion Protein Conformation Significantly

Marco Londei, H. Hawke, Graham Stuart Jackson, 2013 .

Protein Conformation Significantly Influences Immune Responses to Prion Protein1

J. Collinge, A. Clarke, G. Jackson, 2005, The Journal of Immunology.

Tissue Transglutaminase Activation Modulates Inflammation in Cystic Fibrosis via PPARγ Down-Regulation1

V. Villella, V. Raia, L. Maiuri, 2008, The Journal of Immunology.

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy

D. de Ruysscher, J. Laurent, M. Verheij, 2015, Journal of Translational Medicine.

Abituzumab combined with cetuximab plus irinotecan versus cetuximab plus irinotecan alone for patients with KRAS wild-type metastatic colorectal cancer: the randomised phase I/II POSEIDON trial.

C. Bokemeyer, E. Van Cutsem, J. Tabernero, 2015 .

Definition of unique traits of human CD4-CD8- alpha beta T cells.

S. Quaratino, M. Londei, A. Verhoef, 1993, Clinical and experimental immunology.

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy

D. de Ruysscher, J. Laurent, J. Haanen, 2015, Journal of Translational Medicine.

Human Autoreactive T‐Cell Clones Show Flexibility in Recognizing Overlapping Microepitopes, but Inflexibility in T‐Cell Receptor Usage a

M. Feldmann, O. Acuto, S. Quaratino, 1995, Annals of the New York Academy of Sciences.

33781 Sustained and durable response up to 24 weeks after last dose observed in a phase 2a study (NCT03754309) of amlitelimab (KY1005, SAR445229) a novel nondepleting anti-OX40Ligand (OX40L) mAb in patients with moderate to severe atopic dermatitis (AD)

T. Bieber, M. Cork, S. Weidinger, 2022, Journal of the American Academy of Dermatology.

Correction: SUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation

V. Villella, V. Raia, L. Maiuri, 2014, Journal of Immunology.

SUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation1

V. Villella, V. Raia, L. Maiuri, 2009, Journal of Immunology.

Safety and efficacy of amlitelimab, a fully human, non-depleting, non-cytotoxic anti-OX40Ligand monoclonal antibody, in atopic dermatitis: results of a phase IIa randomised placebo-controlled trial.

T. Bieber, M. Cork, S. Weidinger, 2023, The British journal of dermatology.