D. Whittaker

发表

Properties of polymeric zirconium phosphates as Friedel-Crafts catalysts

M. Costa, R. Johnstone, D. Whittaker, 1995 .

Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor.

Peter Ballard, Simon J Brown, Nathaniel G. Martin, 2014, Journal of medicinal chemistry.

Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation.

Jon Winter, David Whittaker, Gareth Davies, 2012, Journal of medicinal chemistry.

Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors.

Matthew Grist, C. Chuaqui, Qing Cao, 2017, Journal of medicinal chemistry.

Process Development of a Suzuki Reaction Used in the Manufacture of Lanabecestat

Rebecca E. Meadows, D. Whittaker, M. C. Evans, 2018, Organic Process Research & Development.

An efficient one-pot synthesis of 2-bromo-6-aryl[5H]pyrrolo[2,3-b]pyrazines

Rafal P. Wiewiora, D. Whittaker, S. St-Gallay, 2015 .

Conformational studies of monoterpenes. II–conformational studies of bicyclo[3.1.1]heptane derivatives by 13C NMR

D. Whittaker, C. M. Holden, 1975 .

The NMR spectra and conformations of cyclic compounds: IX—conformational studies of bicyclo(3,1,0)hexane derivatives by 13C NMR

R. J. Abraham, D. Whittaker, C. M. Holden, 1974 .

Online monitoring of a photocatalytic reaction by real-time high resolution FlowNMR spectroscopy.

S. Coombes, D. Whittaker, A. Codina, 2018, Chemical communications.

Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153).

C. A. Roberts, A. Rabow, M. Waring, 2016, Journal of medicinal chemistry.

The global characterisation of a drug-dendrimer conjugate - PEGylated poly-lysine dendrimer.

D. Buttar, Tony W. T. Bristow, N. Mahmoudi, 2022, Journal of pharmaceutical sciences.

Catalysis of terpene rearrangements by zirconium phosphates and zirconium organo-substituted phosphonates

M. Costa, R. Johnstone, D. Whittaker, 1998 .

Heterogeneous catalysis of nucleophilic substitution

D. Whittaker, T. M. Parker, Lisa F. Hodson, 1993 .

Metal(IV) phosphate catalysed retro-Prins reaction involving an oxetane intermediate

R. Johnstone, D. Whittaker, Ling Lu, 1999 .

The mechanism of gas-phase dehydration of cyclohexanol and the methylcyclohexanols catalysed by zirconium phosphate and zirconium phosphite

M. Costa, R. Johnstone, D. Whittaker, 1999 .

Kinetics of the Meerwein-Ponndorf-Verley reaction

D. Whittaker, V. J. Shiner, 1969 .

Hydrogenation of alkenes over palladium and platinum metals supported on a variety of metal(IV) phosphates

R. Johnstone, D. Whittaker, Ling Lu, 2003 .

Asymmetric substitutions of 2-lithiated N-boc-piperidine and N-Boc-azepine by dynamic resolution.

D. Whittaker, D. Leonori, I. Coldham, 2010, Chemistry.

Efficient Radical Coupling of Organobromides Using Dimanganese Decacarbonyl

D. Whittaker, B. C. Gilbert, C. Lindsay, 1999 .

Radical cyclisations promoted by dimanganese decacarbonyl: A new and flexible approach to 5-membered N-heterocycles

D. Whittaker, B. C. Gilbert, C. Lindsay, 1999 .

The mechanism of formation of 8,8-dimethyl[4.2.1.03,7]nonan-6-yl acetate (fortesyl acetate) during acetolysis of nopyl toluene-p-sulfonate

A. Fortes, R. Johnstone, D. Whittaker, 1999 .

Heterogeneous liquid phase catalysis by metal (IV) phosphates of cyclic ether formation and a reverse Prins reaction

R. Johnstone, D. Whittaker, Ling Lu, 2000 .

The Mechanism of the Meerwein-Ponndorf-Verley Reaction

D. Whittaker, V. J. Shiner, 1963 .

The Structures of Some Aluminum Alkoxides

D. Whittaker, V. J. Shiner, V. Fernandez, 1963 .

The Structures of Complexes of Ethylenediamine with Some Aluminum Alkoxides

D. Whittaker, V. J. Shiner, 1965 .

Initiation of radical cyclisation reactions using dimanganese decacarbonyl. A flexible approach to preparing 5-membered rings

D. Whittaker, B. C. Gilbert, C. Lindsay, 2000 .

Dynamic resolution of N-Boc-2-lithiopiperidine.

D. Whittaker, D. Leonori, I. Coldham, 2008, Chemical communications.

Asymmetric lithiation-substitution of amines involving rearrangement of borates.

H. Adams, D. Whittaker, V. Aggarwal, 2008, Organic letters.

Dynamic kinetic and kinetic resolution of N-Boc-2-lithiopiperidine.

D. Whittaker, I. Coldham, Jignesh J. Patel, 2007, Chemical communications.

Asymmetric deprotonation of N-Boc-piperidines

P. O’Brien, D. Whittaker, I. Coldham, 2007 .

A basic acetato complex of tungsten

D. Whittaker, T. A. Stephenson, 1969 .

Efficient Radical Coupling of Organobromides Using Dimanganese Decacarbonyl.

D. Whittaker, B. C. Gilbert, C. Lindsay, 1999 .

Reactions of some cyclic ethers in superacids

D. Whittaker, D. V. Banthorpe, G. Carr, 1989 .

The NMR spectra and conformations of cyclic compoundsV: Proton couplings and chemical shifts in bridged cyclobutanes

R. J. Abraham, D. Whittaker, M. A. Cooper, 1972 .

Stable carbocations. 220. Carbon-13 NMR spectroscopic study of potential tris- and bishomocyclopropenyl cations

G. Olah, G. Prakash, D. Whittaker, 1979 .

Electrochemistry of ITO and gold electrodes covalently modified with dithizone and the effect of Cu(II) and Pb(II) ions

D. Whittaker, D. Schiffrin, Fakhradin Mirkhalaf, 1998 .

Radical Cyclizations Promoted by Dimanganese Decacarbonyl: A New and Flexible Approach to 5‐Membered N‐Heterocycles.

D. Whittaker, B. C. Gilbert, C. Lindsay, 1999 .

Rearrangements of pinane derivatives

D. Whittaker, D. V. Banthorpe, 1966 .

Reactions of bis(trifluoromethyl)phosphine with some organocobalt complexes

D. Whittaker, R. Dobbie, 1974 .

The reaction of iron carbonyl complexes with bis(trifluoromethyl)-phosphine and tetrakis(trifluoromethyl)diphosphine

D. Whittaker, M. J. Hopkinson, R. Dobbie, 1972 .

Mechanism of heterogeneous gas phase dehydration of 1-methylcyclohexanol catalysed by metal(IV) phosphates

R. Johnstone, D. Whittaker, Jun-Yao Liu, 2001 .

Catalysis of gas and liquid phase ionic and radical rearrangements of α- and β-pinene by metal(IV) phosphate polymers

M. Costa, R. Johnstone, D. Whittaker, 1996 .

The NMR spectra and conformations of cyclic compounds–VIII. Car-3-ene†

R. J. Abraham, D. Whittaker, M. A. Cooper, 1973 .

The Preparation and Stereochemistry of Pinane Derivatives

D. Whittaker, D. V. Banthorpe, 1966 .

The NMR spectra and conformations of cyclic compounds—VII: The conformations of β-pinene, pinocarvone and the cis- and trans-pinocarveols†

R. J. Abraham, D. Whittaker, H. Indyk, 1973 .

Stereochemistry of the verbenols

D. Whittaker, M. Cooper, U. Scheidegger, 1967 .

The NMR spectra and conformations of cyclic compounds–III: The conformations of some pinane derivatives

R. J. Abraham, D. Whittaker, M. A. Cooper, 1969 .

Ring opening of α-pinene epoxide

D. Whittaker, G. Carr, A. P. Millar, 1994 .

The conformations of bicyclo[3.1.0]hexane derivatives by 1H and 13C NMR

D. Whittaker, J. Rees, 1981 .

Rearrangements of pinane derivatives. Part III. Solvolysis of the 2-pinanyl p-nitrobenzoates

D. Whittaker, J. Salmon, 1971 .

The molecular structures of cis- and trans-3-chloro-bicyclo[3,1,0]-hexane

D. Whittaker, R. Seip, P. Bakken, 1984 .

Chemistry of thujane derivatives

D. Whittaker, D. V. Banthorpe, 1972 .

Pyrolysis of Esters of Borneol and isoBorneol

D. Whittaker, C. A. Bunton, K. Khaleeluddin, 1961, Nature.

Cross-resistance studies on two K562 sublines resistant to diaziridinylbenzoquinones.

T. Ward, T. Howard, D. Whittaker, 1995, Biochemical pharmacology.

Potent and selective bivalent inhibitors of BET bromodomains.

A. Dulak, A. Rabow, M. Waring, 2016, Nature chemical biology.

Structure-based design of peptidomimetic antagonists of p56lck SH2 domain

I. E. Smith, N. Borkakoti, D. Banner, 2002 .

452. Intermediates in the decomposition of aliphatic diazo-compounds. Part III. Thermal decomposition of diphenyldiazomethane in acetonitrile

D. Whittaker, D. Bethell, J. D. Callister, 1965 .

The acid catalysed hydration of sabinene and α-thujene

D. Whittaker, M. Cooper, C. M. Holden, 1973 .

Intermediates in the decomposition of aliphatic diazo-compounds. Part VIII. The mechanism of ether formation from diarylmethylenes and alcohols

D. Whittaker, D. Bethell, A. Newall, 1971 .

Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis.

Mark Cockerill, J. Debreczeni, S. Guichard, 2015, Journal of medicinal chemistry.

Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction

Lucinda V. Jackson, Chris D. Parsons, D. Whittaker, 2020, Organic Process Research & Development.

A binuclear dihydride of iron, H2Fe2(CO)6[P(CF3)2]2

D. Whittaker, R. Dobbie, 1970 .

Modulators of the human CCR5 receptor. Part 3: SAR of substituted 1-[3-(4-methanesulfonylphenyl)-3-phenylpropyl]-piperidinyl phenylacetamides.

Simon J Brown, D. Whittaker, J. G. Cumming, 2006, Bioorganic & medicinal chemistry letters.

ZWEIKERNIGES EISENDIHYDRID, H2FE2(CO)6(P(CF3)2)2

D. Whittaker, R. Dobbie, 1970 .

38. The structure of the “nitrenes.”

D. Whittaker, J. Owen, T. W. Taylor, 1938 .

Modulators of the human CCR5 receptor. Part 2: SAR of substituted 1-(3,3-diphenylpropyl)-piperidinyl phenylacetamides.

D. Whittaker, J. G. Cumming, K. Grime, 2005, Bioorganic & medicinal chemistry letters.

Stereochemistry and mechanism

P. Atkins, D. Whittaker, 1973 .